Cpip017256.1


Basic Information
Transcription Factor Domain
Sequence Information
Similer Transcription Factors

Basic Information

Insect
Culex pipiens
Gene Symbol
Rfx7
Assembly
GCA_016801865.2
Location
NC:158559339-158596122[+]

Transcription Factor Domain

TF Family
RFX
Domain
RFX domain
PFAM
PF02257
TF Group
Basic Domians group
Description
RFX is a regulatory factor which binds to the X box of MHC class II genes and is essential for their expression. The DNA-binding domain of RFX is the central domain of the protein and binds ssDNA as either a monomer or homodimer [1]. It recognize X-boxes (DNA of the sequence 5'-GTNRCC(0-3N)RGYAAC-3', where N is any nucleotide, R is a purine and Y is a pyrimidine) using a highly conserved 76-residue DNA-binding domain (DBD) [2].
Hmmscan Out
# of c-Evalue i-Evalue score bias hmm coord from hmm coord to ali coord from ali coord to env coord from env coord to acc
1 2 1e-31 3.3e-28 98.6 0.0 3 77 214 288 212 290 0.97
2 2 6.4 2.1e+04 -3.3 0.1 28 44 512 529 511 530 0.77

Sequence Information

Coding Sequence
ATGTCCACACCGAACCCGTTCCAGCCGTGGAAGCAGCAAAACCGGCCTCCCGGAATACCCCCCAACCTGTCCACGAACAACAGCTATGGAAAATTACCCGCCGTCGCCCATCAGAATCAAATGCAATCgattcaacagcagcagcagcagcatcttcTGCTAAGCCACTCAGCGCCGGTGATCCAGTCGGCCCCATCGCCATCCTCGTCGGCCATTTCGTCGAGCACGGGAGGATCGGCCATGGGGACGGCCGGGATGAGTGAATTTCTGTCTCAGCTGGGGGCCAACAAGCTGATGCTGAGCAAACTTAGTGCCAGCTACGGGTTGGCGGTGGCGCCATCCGCCGGTGATCAGCACCAGCAGAACCATCACCAGCAGCTGatgcaacaacagcagcagcatctcTCCCCGCCGGATGATTGTGCCAGCGACAAGGAGCGCGAGCAGCGAATTCAGCAGATTTTTGAAAGTGCGATTGGGGACAACTCCAAAAAGCAAATCGTGGACATTCTGGAGAAGATTTCCTCGCTCAGGCCACCCGAGCGATTACTGTTGTACCTGCGAATGCCCGGCGGCTATCCTGAAACTGATCCCCTGCGACAGTCCCAGAACCCGCTGGGTACCCGTTCCGAGATCAACCACACCATCAACTGGGTCCGGTCGCACCTGGAGCACGATCCGAACGTGTCCATTCCGAAGCAGGAGGTGTACGAAGATTACATTGCCTTCTGCGAACGGATCGACATCAAGCCGCTGTCGACGGCAGACTTCGGCAAGGTGATGAAGCAGGTCTTTCCGGGCATTCGACCCCGGCGGCTCGGTACGCGTGGCCACTCGCGCTACTGCTACGCGGCCATGCGCAAAGCCACCAAACTGGCAGCCCCCAAGTTGCCCGATCTCAGCACGCCCAGCGCCGCGGGCAGCAGCACCGGCCACAGTGGCGGCGAGAAGAACTCCGATGACCCGGAGGAGCACGTGCCAACGGACGAGGAAGCGTGGAAGGTGATCAAGGTGTGGGCGGAGGCGATGCTGCCGAGTTCGTTCGGCACGATCAACGAGCTGGCCGGGTTCATCAACAAGAACAATCTCAACTCGCCGACCAGCATCGCCAGCCGGCAGCTGCTGCAGAAGAAGCTGATGCAGCGCGAGCTCAAGGAGCGGAAGAAGCTAACCGCGGCCGCCATGAAAAAGCGACGAAAGAAGCGCCGGAAAACGCTCTCCACCAGCGTCGattccgagcagcagcagcagcaggacccTTCCGAAGCAACCCCCGGCGGCAACTCGTCGTCGCTCACCTCAGCCTCCACCACCGAGGCCGCCGAAAATCTGCTCCAGCAAATGATCAAACACGAACCGGAGGTAGATTTCACCGACGaggacaacaacaacacaaccgTCGCCCCAGGAGTTGGCGCCACAAGTGTCATTACACTCAAGCAGCAAAGTACAAACGTCGTCTGTGATACCGGTGGTGGTGTCGTGGGTCATCAGACTCCGGCCGGTGGCCGGGAGATGCGAAGCCCGGCGGAGGAGTACACGATATTCTGTAAGAAGGTGCGCCAGGCGCAGCAGCTGAAGGCGGCGGCTCAGTTGCAGCAGCAAATGCCACAGCCGGCGGTGCCTCCGCCGccgcagcagcatcagcaggtTGTGCCGAGTCCGTTGAGGATTCCGAGTGCCGCGGCGAAGCGGGCCGCCTCGATAGCGCACATGACGCGCCAGAAGCGGTTGAGAttgttgcagcagcagcagcagcgctcGCTGGAAGCGCAGAATAACAGTGCGCCGCGGTATGACGAGTTGGGGAATTTGATTTTGATCGAGAGTCAGGACTTGGTGACGAGTAGCAGCAAGGAGGACTTTATCATACCGAGGGAGCGGGTTATTAGCATTTGCAACATGGACAAGAACGCGTTGGACGATTACTTGAACTGTGACGAGGAGAACTCGCAGGATCAGGACCAGGAGCTGCTGCAGTACTTTCCGGAGGAGAATCAGGGTGCgggacagcagcagcaacatcaaCAGCATCAACAGGGTAGTGTTGACTCGGGGAGTGCCGGGTACGGTGGGATGTTTGAGGATAGTGAGCAGAACTTGAAGTTGTCGCAGCTTCGTAGCATGTTGGAACTGAATATGGCGCAGAGCAGTGGTGCGATGGACAAACCGCAGCATCAGCAGCTTCAGATTGGAGGTCAGTTGGACGGGTTTGATGGCGCGGGGGTGAGTCAACAGCAGATGAGTTTGCAGCCGGGTTCGGCTGCGGCTTCGTTGGCGATGCTGTCCCAGCGTCATCATGGTGGGAGTTTGAGTGCTGGTGGAGCTTCTGAAGGTAAGAAAGCAAACGTTGAAGGGTTCAACAGTTTAGGAAACTGTAGCGGGCAGGCAGGTCCGTCGCAGAGTCCAAACGGAAGACGCAAAAATTGTAGCTTTGTGCCCATTTCTGCGGGTCCTCAATCTCCGCGAGTTCAACCTGCAAGCAAACCGCAAAACAACAACAGTACGCCGAACGCTAGTCCATTCGTGAGTCCACGGAACACTCCGATTCATCGGAAAAGCAAGGCCATCAACAATGGTCTCACCTTGAGCATTTTGCAGCATAACCAGTCCGGCTTTCATCAGCCCCAGCGAGCTCCATTCATGAAGAACGAGCTGTCCGCTTCGGCGCCGCCAAGCCCGTCGCTCGTACAGAGTTACAGATTCTCCATGAATTCGGGCATGCACGGCAACCAGAACGCTCCTCTGCCCTCGTTCCAGCCGATTTGTGGCCCATCCTCTCAAATGCAGAACATGCCCGGCGGCGGTTCGCTCGAGTCGCGATCCAGCAGTGTTCCGTTGATCCCCAACTACGACGGGTACAGCCATTCCAACTTTACCTCCATCTCGCAAACCCCGGTTCCGTCCGAGTGTGACGACTTCTCCGACCCGAACAACATCCTGGACATGCTGAACGAACCgccgtcctcgtcgtcgtccaaCGTCGTCCGCCCGGCCATCAAACTCGAAGACCAGGAGCCATCCATCGCGGACATCCTCGACCAACACGAggaaatgttcaacaaatcttcCATCCCGTACAACAGCCTGTCCCGGTCGGTCCCGTCGACGCCACTTCCACACCACATGCCATCGAACCAGCACTGCGGTGGACCCGCACTCAACTCCAACGGGTTCTCCTCCAAGTCCCTGTTCGAGCTGCCCAAGTCGGTGCCCTCCACTCCCATCAGCAACGGCCGAACCGCCGAGTCCCTGTTCCAGTACAGCCCGGAGACGTCGCGCGATTACCTCATCAACGGTAACTCGGTCGAACGCGCCACAGGTAAGCTAACCTCCTTCTACCAAAACCAGTCGGTCGGAAACAACGGCACCGTTGGAATCACCAACAATCCCGTCAACCAACCCGGCACGACGAACGGAACTGCGGGTGGCCCCCAAACAACCACAATTCCCAGTGGACCCTCGTCCGCGTCCGGTCCGGAAATGTCCATGCTGAGCGATGGAATCGATAGCTTCACCGACGCCCTGATCGGTTCCGACCCGCTGCGGTTCCTGTAG
Protein Sequence
MSTPNPFQPWKQQNRPPGIPPNLSTNNSYGKLPAVAHQNQMQSIQQQQQQHLLLSHSAPVIQSAPSPSSSAISSSTGGSAMGTAGMSEFLSQLGANKLMLSKLSASYGLAVAPSAGDQHQQNHHQQLMQQQQQHLSPPDDCASDKEREQRIQQIFESAIGDNSKKQIVDILEKISSLRPPERLLLYLRMPGGYPETDPLRQSQNPLGTRSEINHTINWVRSHLEHDPNVSIPKQEVYEDYIAFCERIDIKPLSTADFGKVMKQVFPGIRPRRLGTRGHSRYCYAAMRKATKLAAPKLPDLSTPSAAGSSTGHSGGEKNSDDPEEHVPTDEEAWKVIKVWAEAMLPSSFGTINELAGFINKNNLNSPTSIASRQLLQKKLMQRELKERKKLTAAAMKKRRKKRRKTLSTSVDSEQQQQQDPSEATPGGNSSSLTSASTTEAAENLLQQMIKHEPEVDFTDEDNNNTTVAPGVGATSVITLKQQSTNVVCDTGGGVVGHQTPAGGREMRSPAEEYTIFCKKVRQAQQLKAAAQLQQQMPQPAVPPPPQQHQQVVPSPLRIPSAAAKRAASIAHMTRQKRLRLLQQQQQRSLEAQNNSAPRYDELGNLILIESQDLVTSSSKEDFIIPRERVISICNMDKNALDDYLNCDEENSQDQDQELLQYFPEENQGAGQQQQHQQHQQGSVDSGSAGYGGMFEDSEQNLKLSQLRSMLELNMAQSSGAMDKPQHQQLQIGGQLDGFDGAGVSQQQMSLQPGSAAASLAMLSQRHHGGSLSAGGASEGKKANVEGFNSLGNCSGQAGPSQSPNGRRKNCSFVPISAGPQSPRVQPASKPQNNNSTPNASPFVSPRNTPIHRKSKAINNGLTLSILQHNQSGFHQPQRAPFMKNELSASAPPSPSLVQSYRFSMNSGMHGNQNAPLPSFQPICGPSSQMQNMPGGGSLESRSSSVPLIPNYDGYSHSNFTSISQTPVPSECDDFSDPNNILDMLNEPPSSSSSNVVRPAIKLEDQEPSIADILDQHEEMFNKSSIPYNSLSRSVPSTPLPHHMPSNQHCGGPALNSNGFSSKSLFELPKSVPSTPISNGRTAESLFQYSPETSRDYLINGNSVERATGKLTSFYQNQSVGNNGTVGITNNPVNQPGTTNGTAGGPQTTTIPSGPSSASGPEMSMLSDGIDSFTDALIGSDPLRFL

Similar Transcription Factors

Sequence clustering based on sequence similarity using MMseqs2

100% Identity
iTF_00401446;
90% Identity
iTF_00401446;
80% Identity
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