Basic Information

Transcription Factor Domain

TF Family: zf-GAGA
Domain: zf-GAGA domain
PFAM: PF09237
TF Group: Zinc-Coordinating Group
Description: Members of this family bind to a 5'-GAGAG-3' DNA consensus binding site, and contain a Cys2-His2 zinc finger core as well as an N-terminal extension containing two highly basic regions. The zinc finger core binds in the DNA major groove and recognises the first three GAG bases of the consensus in a manner similar to that seen in other classical zinc finger-DNA complexes. The second basic region forms a helix that interacts in the major groove recognising the last G of the consensus, while the first basic region wraps around the DNA in the minor groove and recognises the A in the fourth position of the consensus sequence [1].
Hmmscan Out: # of c-Evalue i-Evalue score bias hmm coord from hmm coord to ali coord from ali coord to env coord from env coord to acc

1 6 0.3 5.9e+03 -0.8 0.1 27 44 83 100 79 104 0.81

2 6 0.0001 2 10.2 0.2 21 46 105 130 101 133 0.90

3 6 0.005 97 4.9 0.2 21 44 133 156 130 160 0.90

4 6 0.00046 9.1 8.1 0.2 21 47 161 187 159 194 0.87

5 6 0.14 2.7e+03 0.2 0.1 23 51 191 219 189 220 0.83

6 6 4.3e-06 0.085 14.6 0.1 23 47 219 243 216 250 0.90

#	of	c-Evalue	i-Evalue	score	bias	hmm coord from	hmm coord to	ali coord from	ali coord to	env coord from	env coord to	acc
1	6	0.3	5.9e+03	-0.8	0.1	27	44	83	100	79	104	0.81
2	6	0.0001	2	10.2	0.2	21	46	105	130	101	133	0.90
3	6	0.005	97	4.9	0.2	21	44	133	156	130	160	0.90
4	6	0.00046	9.1	8.1	0.2	21	47	161	187	159	194	0.87
5	6	0.14	2.7e+03	0.2	0.1	23	51	191	219	189	220	0.83
6	6	4.3e-06	0.085	14.6	0.1	23	47	219	243	216	250	0.90

Coding Sequence: ATGTATAGAGATGATTTTGATAATGTCAGACCTGAAGACCAAGCAATTGATTACGTTACCATAACAGATGTAACAAACTCGCCTGATAATTTTTCCAGTACTTCTTTTGACACTTCAACAGATGTCTTTATTAACACAACAGATAATTGCTCTTTAAATGACCACAACTactcaaataatgtaaatactcAAATGCCCACTTATAACGTAAATCTTGCGTTGCTACTAAGAAATGCTAGcCATAAATGTGGGTTTTGTGACCAGCTTTTTGTTAATGTTACTTCGCTGCGAAGGCATGTAAGGTGTCATACAAAGGAACAACCATTTAAGTGCCAAATCTGTGGTAAATGCTTTTCACAACAAAGCAACTTATGGAAACATATTCGGATTCATACAggaGAACGTCCTTTCGAATGTCCAGAGTGCAAAAGGAAATTCTCACAAAGAGCAAATATGCAGAAACATATGTTGATtcattctggtgaaaaaccgtatGAATGCCCATACTGCTGGCGAACGTTCAGTCAATTAGCTAATCGTAACAAACATGTGCAACTCCACTTAGGCACTCGACCTCACAAATGTAAATACTGTGCCAAAGCTTTTTCCCAGCGTTCAAACATGCTTAAGCATCAGTATCTACATGAGGGAATCAAACCTTTTACTTGTCAGATTTGCCATGTCTCATTTTCTCAGCAGAACAATCTACAAAAACACTTAGCGTTGCATACTGATGAAAAATTGTGTGTTTGTAGAGGCTGTGGAAAAGCttatgtacaaaaaattaaccTAACTATGCACAAGCAACAATGTTCAGAACAGATATTGCAAACCATCGAAAGTCTGTTGGATACAGGGGCAAATACCTACCTCACAATTATTCAGCTAGAtggtaaacaaaacaattattatattaatgaaCATAATGAGCTGATCAAATTAGAAGAAGATGCTGAAACACCGGAAATAGAAGGGAGTAATTCAAATGACTCAAGTTTTTTCTCCAGTgcctaa
Protein Sequence: MYRDDFDNVRPEDQAIDYVTITDVTNSPDNFSSTSFDTSTDVFINTTDNCSLNDHNYSNNVNTQMPTYNVNLALLLRNASHKCGFCDQLFVNVTSLRRHVRCHTKEQPFKCQICGKCFSQQSNLWKHIRIHTGERPFECPECKRKFSQRANMQKHMLIHSGEKPYECPYCWRTFSQLANRNKHVQLHLGTRPHKCKYCAKAFSQRSNMLKHQYLHEGIKPFTCQICHVSFSQQNNLQKHLALHTDEKLCVCRGCGKAYVQKINLTMHKQQCSEQILQTIESLLDTGANTYLTIIQLDGKQNNYYINEHNELIKLEEDAETPEIEGSNSNDSSFFSSA

Sequence clustering based on sequence similarity using MMseqs2