Cvid000182.1
Basic Information
- Insect
- Cryptus viduatorius
- Gene Symbol
- topi
- Assembly
- GCA_964006125.1
- Location
- OZ023220.1:1518689-1520973[-]
Transcription Factor Domain
- TF Family
- zf-C2H2
- Domain
- zf-C2H2 domain
- PFAM
- PF00096
- TF Group
- Zinc-Coordinating Group
- Description
- The C2H2 zinc finger is the classical zinc finger domain. The two conserved cysteines and histidines co-ordinate a zinc ion. The following pattern describes the zinc finger. #-X-C-X(1-5)-C-X3-#-X5-#-X2-H-X(3-6)-[H/C] Where X can be any amino acid, and numbers in brackets indicate the number of residues. The positions marked # are those that are important for the stable fold of the zinc finger. The final position can be either his or cys. The C2H2 zinc finger is composed of two short beta strands followed by an alpha helix. The amino terminal part of the helix binds the major groove in DNA binding zinc fingers. The accepted consensus binding sequence for Sp1 is usually defined by the asymmetric hexanucleotide core GGGCGG but this sequence does not include, among others, the GAG (=CTC) repeat that constitutes a high-affinity site for Sp1 binding to the wt1 promoter [1].
- Hmmscan Out
-
# of c-Evalue i-Evalue score bias hmm coord from hmm coord to ali coord from ali coord to env coord from env coord to acc 1 16 0.043 3.9 8.5 1.0 1 23 258 280 258 280 0.96 2 16 0.01 0.94 10.4 0.9 2 23 287 309 286 309 0.95 3 16 1.6 1.4e+02 3.5 0.1 2 20 316 334 315 336 0.91 4 16 1.1e-05 0.001 19.8 0.8 1 23 343 365 343 365 0.97 5 16 1.1e-06 9.7e-05 22.9 1.5 1 23 371 393 371 393 0.98 6 16 5.2 4.7e+02 1.9 1.5 2 23 405 426 404 426 0.72 7 16 0.71 63 4.7 2.6 1 23 440 462 440 462 0.95 8 16 4.2 3.8e+02 2.2 0.2 1 12 468 479 468 490 0.78 9 16 0.0037 0.33 11.9 1.8 1 23 500 524 500 524 0.90 10 16 0.29 26 5.9 0.0 1 19 539 557 539 560 0.94 11 16 0.026 2.3 9.2 0.0 1 23 565 587 565 587 0.98 12 16 2.4e-06 0.00022 21.8 3.1 1 23 593 615 593 615 0.98 13 16 0.00016 0.014 16.2 0.4 1 23 621 644 621 644 0.97 14 16 0.059 5.3 8.0 0.7 1 23 650 672 650 672 0.89 15 16 3.6e-07 3.2e-05 24.5 0.8 1 23 678 700 678 700 0.99 16 16 7.5e-06 0.00067 20.3 4.9 1 23 706 729 706 729 0.96
Sequence Information
- Coding Sequence
- atgaACGATTTTAAAgacgaatcgatcgatacatTGAGCGAAATGGAGGATGAAATTGACGAACTCGACGAGGAGAGTATCATATGGTCGCAAGAAGAACTTTTATCGTCGTGCGAAACGATGGAACCGGAAGTAAAAACAGAATCGAGCGGAGACTGTTCTTCCGGATCTCTCTGCCGTTTGTGCGCTGCTCGCGTCGTCGATCCTATATACATTTACTCCGAATTTGGAGAATCGATGAAACTTGCGCACAAAATAAATAGCTGTTTAAGCGTCAagatcagaaaaacggatcACCTTCCGAAGCAACTCTGTTCGGTTTGCGTCGAGAAGATAAATTGGTGCGACGCATTCGACGCGCAATGTATCGAAGCCGAAGAAACGCTGCAAGCGATGTTTCGCGACACGAAAGAACCTTCCGATTTAACGGACGTCGTTACGCGCGAAATTCtttccgacgaaaaatcgtgtcCTCTGTGTGTCGAAGGACACATGCAAACGAGTTGCTTAAACGAGCCGACGAGCAGCGGATCGCCGATGGAAGGTATTTTCTACGAAAGCGATATAGTTATCGACAGTAGCGACGAGGAAAAAGCATTGGAGGATCTCGAATTTTCGACGGAAAATCGCGATCCCAACTCTATAATACTAAAATGTTTGGGAAACAGCGAAGAATATCTAAAATGCGGCGCGTGTATGAATCTCTATCACACGCGGGAAAATCTGGACGATCACAAATGCAAACCGAATATTCAGAGCACTTCGCGACCCTATAAATGTCCCGTATGCACCGCTATATTTACCTTTGAGGAACGACTGAATTTTCATATGAAATTTCACAACGGCGCGAAAGAACTTTATTGCAACATTTGCGATGTTACTTTCGCGAAGGAATTGAAGTTATTTTATCATTACAAGCGATATCACTGCGAAAATAACTCGGTGTCGTGTCTGCAATGCGGTAAATTATTGGAAGGTCAGCAGGAGCTGAGGGTTCACGTGTGTTTGGACGGCAAAACGCGTCCGCACGTCTGCGAGGTATGTAACAAAGGATTTTCCGACGGTTACACCTTAAAACGTCACATCGTAACCCATTTGCCGGAAAAACCTTACAAATGTTCGGAATGTGCGAAAAGTTTCACGCAAAAATCGCGACTCAACAAACACATCGCGAGTCACGGTCTCGTAATAGAAAAAACTCAAAACGCATGGAAATGTGCCGAATGCGGTGAGATATTTGATTGTCATGCGAAAGCCGaagatcacgaaaaaaaacacgcgaaaaaatcgatcgcggaaatttcggtatcgaaaatttatcattGCGAATTTTGCAACCGTTATTTCGACGATACGGAGATTCTTCGGGGTCATCAGACTCGTCACGTGATCGAAAATCCGTATACGTGCAATGATTGCGCGAATGTATATAAATCGTTTGCCGAAGCCGTTCCGCATTGGAAGGAACACTCGACGGGGTTTCGTGTCGCGACTTTTTACCTTTGCGATGTTTGCGGCAAAGAGACGAAAGAATTATCATTGCTTCACAAACACAAGCGGAAACGCGAACATTTAACGGCGAGAAAATCggagattaatgaaaatgacgAGAAATTCGTTTGCGAACTTTGCGCTCGGGGATTCGGGAGTATCGAGGAGTTAAGAATTCACGGACAGGAGCAATGCACGAAATTTCCGTGCGATGTTTGCGGCAGTTTATTACCGACTGCGAATTCGCTTTTGGCTCACAAAAGACGACACAGCGGTCTGCGACCGTATGTTTGCAATATTTGCGGCAAAAGTTACACGCAGTCGAGTCACATGTGGACTCACAAGAGATTTCATATGGGGGTAAAACCTTATGCGTGCGAATACTGCGATCAGCGATTCACGATAAAACCCGATTTGGCCGatcatacgagaaaaaaacacacgagaGAACGTCCCTTCAAGTGCGATGTTTGCAATAAGGCGTTTTTAACGGGTTCGGTGTTCTATCAGCATAGACTCATTCATCGGGGGGACAGAAGATACAAGTGCAGTTATTGCGAAAAAGCTTTCACGAGAACCGAAGCATTGAATAATCACATCAAGATACACACGGGCGAGAAACCGCATGCGTGCGATGTGTGCGGACGATGCTTCAGGCAAAAGGGCGATATGCGCAAACATCGACGAACTCAGCACTCGCTTccgaaaaacgaattttcgtga
- Protein Sequence
- MNDFKDESIDTLSEMEDEIDELDEESIIWSQEELLSSCETMEPEVKTESSGDCSSGSLCRLCAARVVDPIYIYSEFGESMKLAHKINSCLSVKIRKTDHLPKQLCSVCVEKINWCDAFDAQCIEAEETLQAMFRDTKEPSDLTDVVTREILSDEKSCPLCVEGHMQTSCLNEPTSSGSPMEGIFYESDIVIDSSDEEKALEDLEFSTENRDPNSIILKCLGNSEEYLKCGACMNLYHTRENLDDHKCKPNIQSTSRPYKCPVCTAIFTFEERLNFHMKFHNGAKELYCNICDVTFAKELKLFYHYKRYHCENNSVSCLQCGKLLEGQQELRVHVCLDGKTRPHVCEVCNKGFSDGYTLKRHIVTHLPEKPYKCSECAKSFTQKSRLNKHIASHGLVIEKTQNAWKCAECGEIFDCHAKAEDHEKKHAKKSIAEISVSKIYHCEFCNRYFDDTEILRGHQTRHVIENPYTCNDCANVYKSFAEAVPHWKEHSTGFRVATFYLCDVCGKETKELSLLHKHKRKREHLTARKSEINENDEKFVCELCARGFGSIEELRIHGQEQCTKFPCDVCGSLLPTANSLLAHKRRHSGLRPYVCNICGKSYTQSSHMWTHKRFHMGVKPYACEYCDQRFTIKPDLADHTRKKHTRERPFKCDVCNKAFLTGSVFYQHRLIHRGDRRYKCSYCEKAFTRTEALNNHIKIHTGEKPHACDVCGRCFRQKGDMRKHRRTQHSLPKNEFS
Similar Transcription Factors
Sequence clustering based on sequence similarity using MMseqs2
- 100% Identity
- iTF_00841315;
- 90% Identity
- iTF_00397536;
- 80% Identity
- -