Basic Information

Transcription Factor Domain

TF Family: zf-GAGA
Domain: zf-GAGA domain
PFAM: PF09237
TF Group: Zinc-Coordinating Group
Description: Members of this family bind to a 5'-GAGAG-3' DNA consensus binding site, and contain a Cys2-His2 zinc finger core as well as an N-terminal extension containing two highly basic regions. The zinc finger core binds in the DNA major groove and recognises the first three GAG bases of the consensus in a manner similar to that seen in other classical zinc finger-DNA complexes. The second basic region forms a helix that interacts in the major groove recognising the last G of the consensus, while the first basic region wraps around the DNA in the minor groove and recognises the A in the fourth position of the consensus sequence [1].
Hmmscan Out: # of c-Evalue i-Evalue score bias hmm coord from hmm coord to ali coord from ali coord to env coord from env coord to acc

1 8 0.01 7.9 6.2 0.2 20 46 96 122 86 128 0.83

2 8 0.38 3e+02 1.2 0.3 22 44 126 148 121 153 0.83

3 8 0.0093 7.2 6.3 1.5 21 44 153 176 144 180 0.83

4 8 0.00031 0.24 11.1 0.4 21 44 181 204 176 209 0.90

5 8 0.018 14 5.4 0.7 21 44 209 232 204 236 0.85

6 8 0.0015 1.2 8.8 0.3 21 44 237 260 229 264 0.84

7 8 8e-05 0.063 12.9 0.1 21 44 265 288 260 292 0.90

8 8 0.0026 2.1 8.1 0.3 21 45 293 317 288 323 0.88

#	of	c-Evalue	i-Evalue	score	bias	hmm coord from	hmm coord to	ali coord from	ali coord to	env coord from	env coord to	acc
1	8	0.01	7.9	6.2	0.2	20	46	96	122	86	128	0.83
2	8	0.38	3e+02	1.2	0.3	22	44	126	148	121	153	0.83
3	8	0.0093	7.2	6.3	1.5	21	44	153	176	144	180	0.83
4	8	0.00031	0.24	11.1	0.4	21	44	181	204	176	209	0.90
5	8	0.018	14	5.4	0.7	21	44	209	232	204	236	0.85
6	8	0.0015	1.2	8.8	0.3	21	44	237	260	229	264	0.84
7	8	8e-05	0.063	12.9	0.1	21	44	265	288	260	292	0.90
8	8	0.0026	2.1	8.1	0.3	21	45	293	317	288	323	0.88

Coding Sequence: ATGAATTATACAACTTCAGAGAAATATGTACTGAATTCAtgtggtgagacatacccaatatctgatgatgcagatcaggccatgaatataaaagctgaggaagttTCAGACACAGAAAAAGAAGAGGAACTTGTCCCAATAACATTTGtggaaataaaggctgaacctgagAGCACTTTGAATGAACTTGAACCTGTACTTGGTGATGAGCAGCAATATTCTCATGATGAGTGTGATAAATCATTCAATGACAGGGGTAATCCGAAGAGGCATCCAAGCGTGCATAGTGGAGAGCAgcgattttgttgtgatgtgtgTGGTAAGTTATTCAATCAGCACAGAACTCTAAAGGAACATAAACACGTACACAGCGTGGAACGGCCATTTAGCTGTGATGTTtgcaataagtcattcagtgttcAGAGttatctgaagagacatcaacgCGTACATAGTagggagcagccattttgctgtCATGTGTGTAATATGTTATTCAGTCATCAGAATAGTCTCAAGAGACATCAACGtgtacatagtggggagcagccatttAGTTGTGATGTGTGCAGCAAGTCATTCCGTGTTCAGTgtaatctgaagagacatcaacgCACACATAGTGGAgagcagccattttgctgttATGTGTGCAATATGTCATTCAGTCATCAGAATAGTCTCAAGCGACATCACCGtgtacatagtggggagcagccatttAGTTGTGATGTGTGCAATATGTCATTCAGTattcagagtaatctgaagagacatcaacgcatacatagtggggagcagccattttcCTGTGAGGTGTGCAATACGACATTCACTGCTTCGAgtaatctgaagagacatcaacgCACACATACtggggagcagccattttcCTGTGAGGTGTGTAATATGTCATTCGGTCACCAGAATAGTCTCAGGAGACATCAACGCATGCATAGTCAGTCATCacagtcatctgaagacacatga
Protein Sequence: MNYTTSEKYVLNSCGETYPISDDADQAMNIKAEEVSDTEKEEELVPITFVEIKAEPESTLNELEPVLGDEQQYSHDECDKSFNDRGNPKRHPSVHSGEQRFCCDVCGKLFNQHRTLKEHKHVHSVERPFSCDVCNKSFSVQSYLKRHQRVHSREQPFCCHVCNMLFSHQNSLKRHQRVHSGEQPFSCDVCSKSFRVQCNLKRHQRTHSGEQPFCCYVCNMSFSHQNSLKRHHRVHSGEQPFSCDVCNMSFSIQSNLKRHQRIHSGEQPFSCEVCNTTFTASSNLKRHQRTHTGEQPFSCEVCNMSFGHQNSLRRHQRMHSQSSQSSEDT

Sequence clustering based on sequence similarity using MMseqs2