Csec007198.1


Basic Information
Transcription Factor Domain
Sequence Information
Similer Transcription Factors

Basic Information

Insect
Cryptotermes secundus
Gene Symbol
MBD-R2
Assembly
GCA_002891405.2
Location
NW:147224-226191[-]

Transcription Factor Domain

TF Family
MBD
Domain
MBD domain
PFAM
PF01429
TF Group
Unclassified Structure
Description
The Methyl-CpG binding domain (MBD) binds to DNA that contains one or more symmetrically methylated CpGs [2]. DNA methylation in animals is associated with alterations in chromatin structure and silencing of gene expression. MBD has negligible non-specific affinity for DNA. In vitro foot-printing with MeCP2 showed the MBD can protect a 12 nucleotide region surrounding a methyl CpG pair [2]. MBDs are found in several Methyl-CpG binding proteins and also DNA demethylase [1].
Hmmscan Out
# of c-Evalue i-Evalue score bias hmm coord from hmm coord to ali coord from ali coord to env coord from env coord to acc
1 2 3.8e-19 7.8e-16 57.0 0.1 6 71 631 696 626 702 0.84
2 2 2.9 6e+03 -3.6 0.0 50 74 1269 1293 1267 1295 0.84

Sequence Information

Coding Sequence
ATGGGTCACCATTGTTGCGTTCCACACTGTGGCTCTAATAGCCGCAGTTCTGGGAATGGAGCAGTCACATTTCATACTTTTCCCATTGACCCAAAGGAACGGAAGTTGTGGATTCTTAGTGTAAGAAGAGCTGATTACAAAAAACTCACAGTTAATAAGCACACTAAAATCTGTTCCAAACATTTTCGGGATGAGGATTTTGTACAGTCCCAGTATTCAAAGCGACGGATGTTGAAGAAGGGTATAGTGCCATCTGTGTTTGCTTTGACTAAAGGGAACCAGGAGGCACCTCAGtgtgaaaagaaaactgaaCATTCTTCACGTGATTCTGGAGACAAAACTTCGAAAGAAGAGGCCAGATCTCAGGCATCTCGTGAGAACAGTTCAAATGCTAGTCAGACTGTTCCACCTGAGATAAAGGAAGCTGATAGGGATCTTTCAGGAAAGACGAAAGTTGGATCTTCTACTTCTAAACACTCTGTGGTTACTGTGGAAAGAAAAGTCAAAGATAAAATTGCCAAGAAAGAGATGAACATTTCAAGTGACAACGCTGCTCATTTACTATCATCAAACTCCACATGTGAGTCTCCTACCAAATCAGATGATTCAGAACAAGGGAGTGTTAGTGACATGACACCTACAAATGGTAGCAGTCCCGCCAACAGTAGCAATGGCACTCCTAGCAGAAGACAGTCCTCTGCACTCAACTTCCAGATTGGCAACAGACTGGAAGCTAAAGACCTAGGAAGTGAAATATGGTATCCTGTCAAAATTGTAGAAGTGGACTGGGATGATGAAGAGATTCTCATACATTTTGAAAAGTGGTCTCAGCGCTACGATGAATGGATCCCAATGGACAGCTCTCGACTTAGACCCATTGAAAATCCAACTCCGCAAAATGATGGTAAGAATGTGTCAAAAGTATTCAATATTGGGGACCGAGTGATGGCAAAATGGAATGACAGCAGACGATATCCAGCCAAAGTCAAAGCTGTGTTGGGGAATGACATGTATGAAGTACTGTTCTTTGATGGTTTTACCAAAAATATAAAGGGAATACGAATGTCAAAACTTGAAAGTGATGCGGATAATATGGCCGAGATAGGTCCTGGACTGTCAGAAAAattgctttcttcaacaataaTTACACCTATCGTGAGGAATGAAGTAATTTCCGAAGCCATTGGCACGAAACAGGAGAGACGAGAacgcaaaaggaaaataaacgtTGTTGAATTGTTTCATCCAAAGAAACGCCAGAAACTTGATCCTGATGCATCATCTTCAAAGTCTTCCTCAGAAGTAGAAAGACGAAAGAAAGCAGAGAAAGGAAAAAGGTGCAAAGAGAGTGACAGTGCTGTCAGTGATGGTCATGGCAATGAAGGTGAGAAGAAGTATATCAACGTGGATACAAATGGGACTGTTCATGAGGCAATTGAGGGTTCAAAAATAGATGAGACAGTGGAGGGAAGACAGGTTGATGAGGATTCTCTGGCTAGGCCAAAGAAGAAGATTGTGCGAAGATCAGGAGGAGGTGCAGATGAGAATGCAGACAAGCCCCGACGTGGCTTGCAGCAGGGAGAGCCTCAAGGGAAAGCTAAGTCTCTTGAAGTGAAATCCTACACAAGGAAAATTCCAGGCAAGATTCCCCTTGGGGGTCAAGAATATCCTTCCACACCCTCAAAGTCAAGACAGGACTCTAGCAAGGGGAATGCAGAAGATGAAGAAGCTCCACGCAGGAGGAGGAAGGATTTTTCAAACAATTCATCCAAATCTGCTAATAGGTCTAATCGTAAGGAGAGTGACAGAGAAGAAACAGTGAAATGGGAAAGTGATGGACAGGCTGGTTTCATTGTGGAAAGTCCAGATGGGCCCAGGAAGACCACTGTTGTTCCTGATAAGAACCTTCCCAGAGGTTGGAGTAAGCATACAATccaacgcaaacatggcaatTCAGCAGGGAAATGGGATGTTATCCTTGtgaatcctcaGGGACGCAGGTTCCGTTCTCGTAATGAGTTGCGACTGTTCTTTGAAGAAAATGGAGAATCTTTCAAGGCAGATATGTTTGACTTTTGCCTCAGTGGTAAAAGGCGCATGTCTCGAACACCTGATGATAGCATTCCAAGTGGAAGGAAAATGTCTCGTGGTCCTGGAGGCAAGGCTAAGGGAATAATAGGTCCTGGTGATGGTGATATGGGAGAACACCAGTCTGTGCCGCAACAGCAGAAACAACAGTTGCAGCCTCAGCGCCGGGTCAAAACATTACTGCCCAAGATCAGGCGCACATCAGCATCTCAGTGTGAAGATGTTGACCGTGAGAAAAATGTTGACCCAACGCCACCTCCCCCACCCTACACTGCAGCTGTAATGTCGGTACCTGCCATCAGAATGGAGACTGAAATGCTTGAAGGTGAAGttctTGTTGGGGGCTtgaaaattcaaatggaaaacaATACATTCAAGTGTCCCAAAGATGGttgtggcaagaattttcgCAAAGAAAATTTGCTACAGATGCATCTCAAACATTATCATCCAGAGTACAACAAATTTATGGGTTCAACTCCAAACGTGGCAGATCTGGCATATGCTCGAACAGTTGGTGAATCAATAGATGACCTCATACCTAAATCACGATATAGTGGTGTTGGTGCCTTTGCTATGGGTAGCACATCATATTCAGAAAAGACAAATCGTTTTGAACCAAGCCGTAAATCTAAAACTGGGCCATCCTTTGGTGTTGGAAGTGGTAAGAGTGGAGGAGTAGGAGGAAATGGAGGTGGTGGAGATTGCAGCACAGCATTGGAAAAAAAGAAGGGAACATCCAAAGAAAAACAATCTTCAGTAGCCACTAAGAAGCCTGGAAAAGGAATGATTGGTGATGGTGATGGACGAGCATCAGCTGATGATGTGTCTGGCGAGAGCAAGGTGCCAAGTGAAGAGAAGTTGACAGTTGTTGAAAATACATCTGCCCCTGTTACTGATATTGCAGCAATAACAACACACAAGGAAGAGAAAAAGGAACCACAGACAACAATTAAAACTCTAATGCCAGTAATTCGATCACCCTCACATGCTCAGGAAATATCAGCAACAGAGCGGTTGAAGAGTAAATTCCCTGCAGTTGAGGAAGGTGAAGAGTATATTGAGGTAATTGATGTGGGACCTCAGCAGATACCACCTACTCATACCACTAGTCtgcagttcatgcctcagtcATCAGTTTCAAACACACAGAGCACCACCAGTTCAACAAAATCTCTTCGTACTATTCGTCGTCGCCGTCTGTCAGACTTCCATTTTGAGCCTTTACATAAGAGGCGTAAGATAGCATCAACATCAAAATTGGATATGTCAGAAGATGCGGCGGATGTAGTGGATGACAGTGGTGGATCCCCGGTGGATGTGAAAACCCCAACAACAGGAACAGTTGGAAGTGGGAGAAGTACTACTACAACATATCGCTACAGCAAGAAAAAGACACCTATTGTTCACCTGGAAAAGTTAAATGTTGTCACAGACAGTAATGGTCGCATCATTTTGTCTCCCTCCGTCCAGGACCAACGAGAATGCAAGTTGCTTGAAACTCCAGCAGCAGAACAGCCTGCAGTGGATCATTTACGGAAGGAGGAACTGATTAACTGCACATGCGGTTTTATGGAGGAGGATGGACTCATGATTCAGTGTGACCTATGTTTATGCTGGCAGCATGGAATATGTAATAATAttgaaaaggaaacagaagtaccAGAAAAATATGTGTGCCCTATTTGCTTAAATCCATATCGCCAGCGCAAGTCAAAGAAATATTTGCATGATCAGGATTGGCTTAAAGAAGGGAAACTGCCAAGtttatCTTTCCGTTCAAAGAATGAATCAAATATTCTTGAAAGGGAAGCCATATTAAAGAGATCTCATGATCTGACAGGATCCTTGCTGCAAATCCAACAGGTTCTTCATAGTCTCAGGGTAAAAGTTAATATCGCAGGGAAATCTGATCACCCAAAATTATATCTATGGGCCAAAAGTTGGGAGAAGGAAGGAGAAAGTTCTTCAGCACAATTGACCTCTGTATCTCAGCAACATGTAGCTGCTGAAGATGAGTTCAAGCCGCAACTTGAAAACAATGCATCATGCAGTCATAACGAGGAGAAAGCAGCATCAGACACCAGCACTGTTGTTCCACCAAAAATGACAGACCAGAAAGATGCCGTGCCTATCCCTGTACCCTCTGAACTTGGACGAGTCGAACATCCTGATGGTAGTAAACAAGATACAAAAACAGGAGACAGAGAGGTGAATTTGGAACAGCAGGTTCAGAAAGAAACTGTAGTAGCTGAAAGAGAAACGTCTGAAGTACATTCTTTATCTGATAAAATAAAAGATGAGAACAGGTTAGATAGAAGAACCTCTGAAAAGAAGCATGAAACAGAAATTGAAGCAGTTACTACTGAGAATGTTGATGGTGTGGAGTCTTCTTTAAGCAATGAACAACATCCTTCATCCACCAATGATCAAAATAATTCTGATTCTAATGCTCCTCCTTCAAATGAAGATCAAGGTACGAAGATAGATCAACTACAGTTACAGTTTGAAGGTACAGCAGACAAACCAGTTTCACCACGTGCACTTGGGAATGTGCACAGACATGACTGTGAAGCATACCCTGCTGCAGAAAAAGTACAAGCAAAAGAAGAAATTTCTGATGCTGGTTCTGAAAATCAGGTAGTGCAGTCTGAAAAGAAAGAAGGTTGCATCAGTGAAGTTTGTTCAGAAGAGAAGTTAGAAGTAACTGACATGTGCAGTTCCTCAGAAGATGTCCCTAAGCAGCTAGATCCAGGCCCAACTGAAGAAACAGTGAAGTCCAATAGTGAGAAGAAACCTGATGAGACCATGTCACGACTGGAGAGTCCTGGGTTGTTGCATCAGACTATAACAAATGCAAATCCTCTAAATAATGGTGGTATAGGAGGTCAGTTGGATACTTCAGGTCATCCCATGTTGCAGCTACCAATCTGTCAGTCGGAGCTCATGCAGTTTGCCAGTACCATAGCAGATAATCTGAGTGCAACAGAACCAGGTCGCCCCGCTGCATCAGGCCCGGTTCCTGTGGCTGAACCTCCAAGAGCACCTCAACCTGAGGCACCCATTGACCCTGTTGAGTGTCGGTCATGTCTACTTGATCACATTGACCACTTCCAAACACAGATTGACACAAGGCTGACAATGCTTGAGGAGCAAGTTGCAGCTCTCGAATCTCAGGATCCAGATGCTGCAAAAGATGAAGGACCCGACTTCTATCCACAAACGAAACAGACAATTCAGATGCTGCTTCGTGATCTTCAAACCATGCGTAAAATTGCTGCCCTTAACTAA
Protein Sequence
MGHHCCVPHCGSNSRSSGNGAVTFHTFPIDPKERKLWILSVRRADYKKLTVNKHTKICSKHFRDEDFVQSQYSKRRMLKKGIVPSVFALTKGNQEAPQCEKKTEHSSRDSGDKTSKEEARSQASRENSSNASQTVPPEIKEADRDLSGKTKVGSSTSKHSVVTVERKVKDKIAKKEMNISSDNAAHLLSSNSTCESPTKSDDSEQGSVSDMTPTNGSSPANSSNGTPSRRQSSALNFQIGNRLEAKDLGSEIWYPVKIVEVDWDDEEILIHFEKWSQRYDEWIPMDSSRLRPIENPTPQNDGKNVSKVFNIGDRVMAKWNDSRRYPAKVKAVLGNDMYEVLFFDGFTKNIKGIRMSKLESDADNMAEIGPGLSEKLLSSTIITPIVRNEVISEAIGTKQERRERKRKINVVELFHPKKRQKLDPDASSSKSSSEVERRKKAEKGKRCKESDSAVSDGHGNEGEKKYINVDTNGTVHEAIEGSKIDETVEGRQVDEDSLARPKKKIVRRSGGGADENADKPRRGLQQGEPQGKAKSLEVKSYTRKIPGKIPLGGQEYPSTPSKSRQDSSKGNAEDEEAPRRRRKDFSNNSSKSANRSNRKESDREETVKWESDGQAGFIVESPDGPRKTTVVPDKNLPRGWSKHTIQRKHGNSAGKWDVILVNPQGRRFRSRNELRLFFEENGESFKADMFDFCLSGKRRMSRTPDDSIPSGRKMSRGPGGKAKGIIGPGDGDMGEHQSVPQQQKQQLQPQRRVKTLLPKIRRTSASQCEDVDREKNVDPTPPPPPYTAAVMSVPAIRMETEMLEGEVLVGGLKIQMENNTFKCPKDGCGKNFRKENLLQMHLKHYHPEYNKFMGSTPNVADLAYARTVGESIDDLIPKSRYSGVGAFAMGSTSYSEKTNRFEPSRKSKTGPSFGVGSGKSGGVGGNGGGGDCSTALEKKKGTSKEKQSSVATKKPGKGMIGDGDGRASADDVSGESKVPSEEKLTVVENTSAPVTDIAAITTHKEEKKEPQTTIKTLMPVIRSPSHAQEISATERLKSKFPAVEEGEEYIEVIDVGPQQIPPTHTTSLQFMPQSSVSNTQSTTSSTKSLRTIRRRRLSDFHFEPLHKRRKIASTSKLDMSEDAADVVDDSGGSPVDVKTPTTGTVGSGRSTTTTYRYSKKKTPIVHLEKLNVVTDSNGRIILSPSVQDQRECKLLETPAAEQPAVDHLRKEELINCTCGFMEEDGLMIQCDLCLCWQHGICNNIEKETEVPEKYVCPICLNPYRQRKSKKYLHDQDWLKEGKLPSLSFRSKNESNILEREAILKRSHDLTGSLLQIQQVLHSLRVKVNIAGKSDHPKLYLWAKSWEKEGESSSAQLTSVSQQHVAAEDEFKPQLENNASCSHNEEKAASDTSTVVPPKMTDQKDAVPIPVPSELGRVEHPDGSKQDTKTGDREVNLEQQVQKETVVAERETSEVHSLSDKIKDENRLDRRTSEKKHETEIEAVTTENVDGVESSLSNEQHPSSTNDQNNSDSNAPPSNEDQGTKIDQLQLQFEGTADKPVSPRALGNVHRHDCEAYPAAEKVQAKEEISDAGSENQVVQSEKKEGCISEVCSEEKLEVTDMCSSSEDVPKQLDPGPTEETVKSNSEKKPDETMSRLESPGLLHQTITNANPLNNGGIGGQLDTSGHPMLQLPICQSELMQFASTIADNLSATEPGRPAASGPVPVAEPPRAPQPEAPIDPVECRSCLLDHIDHFQTQIDTRLTMLEEQVAALESQDPDAAKDEGPDFYPQTKQTIQMLLRDLQTMRKIAALN

Similar Transcription Factors

Sequence clustering based on sequence similarity using MMseqs2

100% Identity
iTF_00396344;
90% Identity
iTF_00396344;
80% Identity
iTF_00396344;