Basic Information

Insect: Cryptophagus acutangulus
Gene Symbol: Hr39
Assembly: GCA_963556235.1
Location: OY744559.1:8980684-8984246[-]

Transcription Factor Domain

TF Family: SF-like
Domain: zf-C4|SF-like
PFAM: AnimalTFDB
TF Group: Zinc-Coordinating Group
Description: The ligand binding domain of nuclear receptor steroidogenic factor 1 (SF-1): SF-1, a member of the nuclear hormone receptor superfamily, is an essential regulator of endocrine development and function and is considered a master regulator of reproduction. Most nuclear receptors function as homodimer or heterodimers, however SF-1 binds to its target genes as a monomer, recognizing the variations of the DNA sequence motif, T/CCA AGGTCA. SF-1 functions cooperatively with other transcription factors to modulate gene expression. Phospholipids have been determined as potential ligands of SF-1. Like other members of the nuclear receptor (NR) superfamily of ligand-activated transcription factors, SF-1 has a central well conserved DNA binding domain (DBD), a variable N-terminal domain, a flexible hinge and a C-terminal ligand binding domain (LBD). [1, 8, 3, 11, 6, 5, 12, 10, 9, 2, 4, 7]
Hmmscan Out: # of c-Evalue i-Evalue score bias hmm coord from hmm coord to ali coord from ali coord to env coord from env coord to acc

1 5 4 3e+04 -7.3 10.2 42 160 146 212 65 277 0.43

2 5 0.65 4.8e+03 -2.7 3.4 48 113 210 279 196 321 0.51

3 5 4.9e-08 0.00036 20.8 0.0 1 24 395 418 395 429 0.87

4 5 0.017 1.2e+02 2.6 0.0 69 119 437 485 416 508 0.62

5 5 2.5e-73 1.8e-69 235.8 0.1 205 408 526 724 505 724 0.96

#	of	c-Evalue	i-Evalue	score	bias	hmm coord from	hmm coord to	ali coord from	ali coord to	env coord from	env coord to	acc
1	5	4	3e+04	-7.3	10.2	42	160	146	212	65	277	0.43
2	5	0.65	4.8e+03	-2.7	3.4	48	113	210	279	196	321	0.51
3	5	4.9e-08	0.00036	20.8	0.0	1	24	395	418	395	429	0.87
4	5	0.017	1.2e+02	2.6	0.0	69	119	437	485	416	508	0.62
5	5	2.5e-73	1.8e-69	235.8	0.1	205	408	526	724	505	724	0.96

Sequence Information

Coding Sequence: ATGGCCGCCGATATGAGGTCTCCGAACGTATCAGTCACTCCAATAAACATGGAGCCATATCCACCGGCCTCATTGAGTACCAGCAGCACCAACGGTGCGGACCATATCCCGGTGGATCCGCCGCAACGTACGCGCAGTGCGCCTCATCCAGCCTCAGTGATCACCAACAACAACGGCACCAGCGACTTATTGGACAGTTCCGATGCTGAGGTCGCTCAGATCCAATTCCAATCCGTCAATATGCGAAATAAGAAGAAGCGCGATGATGTGCTACCAAGGCCGATGAGTTGGGAGGGTGAATTGTCGGATGGGGAACGCGATATGTGCGTCGATGAGGACACGTCGTCGACACAAGTGCCGGAAAACCTCTCGCTTCCATTGTCCAAGCAGACGTCGAACAGTGTGCTGGACTCGAAGGAGAGTCCAATTATGCGACTTAAGCAACAGCCACCGATGGGCACCTATTCGTTGCACAGCACACCCAGCAATTCGCCTTTGTTGAGTCAAAGGCATCCAGTGCCAATTATTAGCCACAAGGATCTCATGCATAAAGCCCTTAACGTTCCACCCACTCCAAGTCCAGATTCTGCCATTCATTCGGCATACAGTGTGTTCAGTTCACCAAATCAAAGTCCGCTAACGCAAAGACATATTACGCTTACGCCGAACTTAAGTAGGAACAATAGTGATGCTTCCCATTCGAGTTGTTGTAGTTATTCCAGTGTTTCGGTCTCGGTATCGCCCACGCAACAATTTTCACCTACTCACAGTCCTATCCAGGGTCGCCATATGCACAGTATTCACAGCAGCCCTTTGCACCACAACATCCTCTATCGTAGCCTGCAGGAAGACCCGACACTTCAATACAATCAGGATCACGATCCACTCGACGAAAGCGAAGACAAAAGTGGCTTGGTCCATACATCATTGCCAGCACAGCCCGGAATTTCCCGTCAGCAACTCATCAACAGTCCTTGTCCGATTTGCGGCGATAAAATCTCCGGCTTCCATTATGGCATCTTCAGTTGCGAGTCTTGCAAAGGCTTCTTCAAACGCACCGTGCAGAACCGCAAGAACTACGTCTGCCTAAGAGGGGCGCAATGTCCAGTGACGGTGGCCACTCGCAAAAAATGTCCCGCATGCCGATTCGACAAGTGTCTGCAATGCGGCATGAAACTCGAGGCGATACGAGAGGATCGGACGCGTGGCGGCAGATCAACGTATCAATGCTCGTATTCGCTTCCTCCATCGTTAACGAATCATGCTGAACTTCGCGCAAGTTCAACGGATCTTAGGTCGGGTATGAATGATGCCCATCATGGACTTACAGTAAAACTGGAACCTCCCGATTCCACTCAATCACATCACAAGCGAGCTGGTTTACCCGGTTCCAAAGGCGTCCCTCCGTTATTGCAAGAAATAATGGATGTGGAGCATCTTTGGCACTACAACGAAATGGAACTGCACAAGTTGAGTACCGAGGGACATTTGGGCAAAGAAGGTTCTAGTGGTGCTGTACATAATCTATCCACACATCCTTTATTAGCGGGTACCGCTCTGGCCGGTACGACCGACACTAATCCTGATTTCGTAGCGAATTTGTGCAATATCGCCGATCATCGACtgtataaaattgttaaatggTGTAAAAGTTTGCCCCTCTTCAAGAACATATCGATTGACGACCAGATATGTTTGCTGATAAATTCCTGGTGCGAGTTGCTCCTTTTCTCCTGTTGTTTTCGCTCGATGACTACACCGGGCGAAATTCGCGTGTCGCTTGGCAAAAGTATAACTTTGAGCCAGGCTCGCGAACTGGGAATGCAAGCCTGCATCGAACGGATGTTGAATTTTACAGAGCAATTACGAAGGCTCCGGGTGGATCAATACGAGTACATTGCGATGAAGGTCATCGTCCTGCTAACTTCTGATACTTCGGAGTTGCGAGAAGCAGAAAAAGTCAGAGCGTCGCAAGAGAAAGCGCTCAAAGCGTTACAAGACTACACTTTAACTCATTATCCTGAAAGTCCGGCGAAATTCGGTGAATTACTGCTGCGCATCCCGGAGTTACAACGAACTTGTCAGGTTGGAAAAGAAATGCTGacaataaaatcaaaagaCGGAGATGGACCAAGCTTTAATCTCCTGATGGAACTTCTTCGCGGGGACCACTAG
Protein Sequence: MAADMRSPNVSVTPINMEPYPPASLSTSSTNGADHIPVDPPQRTRSAPHPASVITNNNGTSDLLDSSDAEVAQIQFQSVNMRNKKKRDDVLPRPMSWEGELSDGERDMCVDEDTSSTQVPENLSLPLSKQTSNSVLDSKESPIMRLKQQPPMGTYSLHSTPSNSPLLSQRHPVPIISHKDLMHKALNVPPTPSPDSAIHSAYSVFSSPNQSPLTQRHITLTPNLSRNNSDASHSSCCSYSSVSVSVSPTQQFSPTHSPIQGRHMHSIHSSPLHHNILYRSLQEDPTLQYNQDHDPLDESEDKSGLVHTSLPAQPGISRQQLINSPCPICGDKISGFHYGIFSCESCKGFFKRTVQNRKNYVCLRGAQCPVTVATRKKCPACRFDKCLQCGMKLEAIREDRTRGGRSTYQCSYSLPPSLTNHAELRASSTDLRSGMNDAHHGLTVKLEPPDSTQSHHKRAGLPGSKGVPPLLQEIMDVEHLWHYNEMELHKLSTEGHLGKEGSSGAVHNLSTHPLLAGTALAGTTDTNPDFVANLCNIADHRLYKIVKWCKSLPLFKNISIDDQICLLINSWCELLLFSCCFRSMTTPGEIRVSLGKSITLSQARELGMQACIERMLNFTEQLRRLRVDQYEYIAMKVIVLLTSDTSELREAEKVRASQEKALKALQDYTLTHYPESPAKFGELLLRIPELQRTCQVGKEMLTIKSKDGDGPSFNLLMELLRGDH

Similar Transcription Factors

Sequence clustering based on sequence similarity using MMseqs2

100% Identity: iTF_00753059;
90% Identity: iTF_01014531;
80% Identity: iTF_00395342;