Cpra005408.1
Basic Information
- Insect
- Cryptocheilus praepositus
- Gene Symbol
- egg
- Assembly
- GCA_033815515.1
- Location
- JAWWQZ010000128.1:915461-922369[+]
Transcription Factor Domain
- TF Family
- MBD
- Domain
- MBD domain
- PFAM
- PF01429
- TF Group
- Unclassified Structure
- Description
- The Methyl-CpG binding domain (MBD) binds to DNA that contains one or more symmetrically methylated CpGs [2]. DNA methylation in animals is associated with alterations in chromatin structure and silencing of gene expression. MBD has negligible non-specific affinity for DNA. In vitro foot-printing with MeCP2 showed the MBD can protect a 12 nucleotide region surrounding a methyl CpG pair [2]. MBDs are found in several Methyl-CpG binding proteins and also DNA demethylase [1].
- Hmmscan Out
-
# of c-Evalue i-Evalue score bias hmm coord from hmm coord to ali coord from ali coord to env coord from env coord to acc 1 2 3.6 1.5e+04 -3.9 0.0 22 38 554 572 550 576 0.64 2 2 6.7e-13 2.8e-09 36.9 0.0 5 71 620 680 617 685 0.88
Sequence Information
- Coding Sequence
- ATGGAAGTTATCGAATTGGTATCGGACGAGGAAGCGTCGGAGGATAATTTTAAGGAAAACAAGGGTCCGAAAATGTATAGCAATAATTGTATTAACTTCAAGTGCAATTCTGGTCTCGACATGAAACCAGCGCCTTCGTTCGCGTGTGCATATTACGGTGTCAACACggacaagaagaagaagaggacaatatgcaaaaagtgttttgATGCTGCTCTAGAGCATCAGAAACAATTAGTATCTGCGCTCATAGATCGCAAGCCATTGTTGCATTGTGATTTTCCCGATCATACTATGGAAGTAGAAATCTCAGACAGTGATGATTCTGAtgacgaaaagaaaaaagtgatagAAGAAGATAAATATCTGCCGGAGGAAGTACTTTTAGATATAGAGGATAAATTGAACAACACGCTGCATTCAATtttcacagaatataatatCGATTATCAATTGAAAGAAACGCAGAAGATTCTTGAAAAGCAATGGGATAAAATAAATGAGGAAAATGAAGTTATGGATAAGGAGGTAAAGAATCTGATGCGTACCATGGATACGCTGCGTAACAGTTTGTATGCAGACTTCAGACCACAAATTCAAATGCTCCAAGAACTTCAAATAGAAGATAGCCCTGGACCAAACATGGTCTACCCACTTGTAGCAACGAAGAAAGTTACTCAAGTACGCCTTTCGCTGAACACCTTGTCACCGGACAATCAACCAGACGTATTATCAATTGAACGAGTTAATAAACAAGTAGTAGCTCTAGATTTACCGCCTAGTGGACCACTTGTGAAACCGCAGCCAGAAGTGGACACTATTGTATATGTTTGGAAGCATGCGCTCATGCCTTGGGTTAAAGGAAAGgtTCAAACTGTCATTTCAAGGATACCATTACATTGTCGTGTGAAATGGCTGCAGAAAAAGTACAATTCAGTAGTAAAGAATACAGTCGGCAAACATCTGGCAGTAGCTATTCCAAGTCAAGTATTAATTCCAGTCGGTACACGAGTCGTCGCGATATTTTATGATGTTCCAGCTAGCAACTTTTACAGTGGCGTTATTGCAGAACCACCAAAATCGACAAACAAATACAGATACCTAGTCTTTTTCGACGACGGGTATGCACAATATGTAACACATCAAAATATTTACGTGGTCGCAGAAAGTTCTACTCGCGTATGGGAAGACATCCCCAACGAATCCCGAGATTTTGTCAAGAAATACTTGGAAACTTATCCGGAGAGGCCGATGGTCAAATTACAGACCGGACAAGTAGTAAGAACGGAGTGGAATGGTAAATGGTGGATTGCAAGGGTTGTACAGGTCGATGCGAGTTTGGTGCAAATGCATTTCGATGCCGACGGAAGGACAGAGTGGATATACAGAGGGTCAGCGCGGCTGGGACCACTTTATTTCGAGTATCTGAAAGCCAATGCTAGACAGCAGGGACACCATGCTTTACTTAACACTCCCAGTCGTCACCGTATTCCGGCTGTTGCAAATAAAAGTAATTTGCCGTACGTCGAATATACGTCTAATAGAGAAACTGAAGACGAATCCACATCGAGTACACAGGCTGAAAAGGTTTCTTTGGGCGAAATATCCGGAAGCACGATCTCAACAGGTAGTAGTCAAACGCAGTCGCGTGCTGTTGCCAGGAAAAGCACCACTAAAAAGTCGCAGAGCACAGTGGACACTATTGCATACAGCCCTGCTACCGAAACGAAACCGTCGCACAGTATAGTTTATTATCAAACGCAAAACAAAATTCAGACGAAGAAGTTTGTACCCCATAAGTGCGGTCCTCAATGCGTTCAAGGGATATCGTTCACTCCTGATGATTTGAGAGGATATTCGCCACTTTCTATACCGTTACTTTGCGGCTGGAACAGACAACTTTGCAAGTATCCGAAggggaagaaaattacattgtaTCAAGCACCTTGTGGAGTGAGACTGCGAAATATGGAGGAATTACATCTCTATCTTCGTACAACAGGCAGCCCAATGTCCGTAGACCTCTTTGATTTTGATCATTGGGTACACTGCTTAGCGGAATTCGTTCTAGACAAGTGTTTCGTTAACATAAAGGACCTTAGTTACGGTGTGGAAAATGTACCGATACCGTGTGTCAATGAATTAGATCACGCTTTACCTGACACCATAAGATACAGCACCCAAAGGGAACCCACGGAAGGTGTTAATCTTAATTTAAATCCCAATTTCTTGTGCAGTTGCGACTGCGAAGACGATTGCCAGGATAAGGAAAAGTGTCAATGCTGGCAACTAACGATACAAGGTGCAACATTAGGCGGACGAGTACCAAATACAGCAGTCGGATACGTGTATAAGCGTTTGCCGGAACCCGTGATTACCGGTATATACGAATGCAATTCAGGATGCAAGTGCGCTGTGAAAACCTGCCTCAATAGAGTTGTGCAGCATCCATTGACGTTGAAGTTGCAAGTATTTAAAACGGCGCCTAGAGGCTGGGGAATACGTTGCCTCAACGATATACCTCTGGGAtcgtttatttgtatatatgccGGAAGATTGCTGACTGAACAGGGTGCCAACGAAGGTGGAAAAAATTACGGTGACGAGTATCTCGCAGAATTGGATTACGTCGAGGTGGTTGAAGGCATTAAAGAAGGATACGAAAGCGACGTCCTTGAGCCTGAAATGCCAATTGGAACGCCGGATGACAGCGAGAAACCTTCTACAGGGAGCGATGACGAagatagtacaaaaataaacgcgAACAATTCGGACGAAGATTTTAATATCGGCCAATACGTGAACTTTGATGTGGAATCCTCGGAACCATCGTCTATCAGgAAACGACTCAGAAAGCGTAAAAGAGAAGACACTCGTCCAGACGGTTCGGAAGACAACAGCGAAGACGGAAGTTTAACGAGGAACTCTGAACAACTAGCGAAACAGTCAGGTGAAAATCGTCCGATGGACACAGACACAATTACGGTTAGCGACGACGAAGAAAATCGAAGTGGCAGGCGAGAACCCAGCAGATTTGATCCAACCGTGGAGCCAACTCAGTTGGACAGACCAAAATTCAAGTCAGTAAGAGACTTCTTCGGCGAAGATGAAGCTGTATATATCATGGATGCAAAGACAACTGGAAATATTGGCCGCTATTTAAACCACTCGTGTGACCCGAACGTATTCGTACAAAACGTTTTTGTTGACACACACGACGTTCGCTTCCCGTGGGTCGCATTTTTTGCTCTGAACTATATAAGAGCCGGACAGGAGTTAACGTGGAATTACAGTTATGACGTAGGAAGTATACCGGGAAAAGTGATCATTTGCAAATGTGGTGCTTCGAACTGCAGGGGCCGTTTATTGTAA
- Protein Sequence
- MEVIELVSDEEASEDNFKENKGPKMYSNNCINFKCNSGLDMKPAPSFACAYYGVNTDKKKKRTICKKCFDAALEHQKQLVSALIDRKPLLHCDFPDHTMEVEISDSDDSDDEKKKVIEEDKYLPEEVLLDIEDKLNNTLHSIFTEYNIDYQLKETQKILEKQWDKINEENEVMDKEVKNLMRTMDTLRNSLYADFRPQIQMLQELQIEDSPGPNMVYPLVATKKVTQVRLSLNTLSPDNQPDVLSIERVNKQVVALDLPPSGPLVKPQPEVDTIVYVWKHALMPWVKGKVQTVISRIPLHCRVKWLQKKYNSVVKNTVGKHLAVAIPSQVLIPVGTRVVAIFYDVPASNFYSGVIAEPPKSTNKYRYLVFFDDGYAQYVTHQNIYVVAESSTRVWEDIPNESRDFVKKYLETYPERPMVKLQTGQVVRTEWNGKWWIARVVQVDASLVQMHFDADGRTEWIYRGSARLGPLYFEYLKANARQQGHHALLNTPSRHRIPAVANKSNLPYVEYTSNRETEDESTSSTQAEKVSLGEISGSTISTGSSQTQSRAVARKSTTKKSQSTVDTIAYSPATETKPSHSIVYYQTQNKIQTKKFVPHKCGPQCVQGISFTPDDLRGYSPLSIPLLCGWNRQLCKYPKGKKITLYQAPCGVRLRNMEELHLYLRTTGSPMSVDLFDFDHWVHCLAEFVLDKCFVNIKDLSYGVENVPIPCVNELDHALPDTIRYSTQREPTEGVNLNLNPNFLCSCDCEDDCQDKEKCQCWQLTIQGATLGGRVPNTAVGYVYKRLPEPVITGIYECNSGCKCAVKTCLNRVVQHPLTLKLQVFKTAPRGWGIRCLNDIPLGSFICIYAGRLLTEQGANEGGKNYGDEYLAELDYVEVVEGIKEGYESDVLEPEMPIGTPDDSEKPSTGSDDEDSTKINANNSDEDFNIGQYVNFDVESSEPSSIRKRLRKRKREDTRPDGSEDNSEDGSLTRNSEQLAKQSGENRPMDTDTITVSDDEENRSGRREPSRFDPTVEPTQLDRPKFKSVRDFFGEDEAVYIMDAKTTGNIGRYLNHSCDPNVFVQNVFVDTHDVRFPWVAFFALNYIRAGQELTWNYSYDVGSIPGKVIICKCGASNCRGRLL
Similar Transcription Factors
Sequence clustering based on sequence similarity using MMseqs2
- 100% Identity
- iTF_00684169;
- 90% Identity
- -
- 80% Identity
- -