Basic Information

Insect: Cryptocephalus primarius
Gene Symbol: KLF2_3
Assembly: GCA_963576515.1
Location: OY754956.1:5937025-5939587[+]

Transcription Factor Domain

TF Family: zf-GAGA
Domain: zf-GAGA domain
PFAM: PF09237
TF Group: Zinc-Coordinating Group
Description: Members of this family bind to a 5'-GAGAG-3' DNA consensus binding site, and contain a Cys2-His2 zinc finger core as well as an N-terminal extension containing two highly basic regions. The zinc finger core binds in the DNA major groove and recognises the first three GAG bases of the consensus in a manner similar to that seen in other classical zinc finger-DNA complexes. The second basic region forms a helix that interacts in the major groove recognising the last G of the consensus, while the first basic region wraps around the DNA in the minor groove and recognises the A in the fourth position of the consensus sequence [1].
Hmmscan Out: # of c-Evalue i-Evalue score bias hmm coord from hmm coord to ali coord from ali coord to env coord from env coord to acc

1 14 4.2 2.5e+03 -1.1 0.1 26 46 107 127 91 132 0.71

2 14 0.0027 1.6 9.1 0.2 22 46 159 183 150 190 0.86

3 14 0.049 29 5.1 0.1 22 45 188 211 183 218 0.89

4 14 1.2 7e+02 0.6 0.0 22 51 216 245 211 246 0.83

5 14 0.00027 0.16 12.3 0.1 22 47 244 269 231 275 0.88

6 14 0.052 31 5.0 0.0 11 47 288 325 279 330 0.80

7 14 0.034 20 5.6 0.2 21 43 327 349 324 352 0.93

8 14 0.39 2.4e+02 2.2 0.1 13 48 443 482 441 486 0.71

9 14 0.0065 3.9 7.9 0.0 22 52 484 514 481 516 0.87

10 14 0.0045 2.7 8.4 0.1 21 51 539 569 527 571 0.86

11 14 0.23 1.4e+02 2.9 0.1 17 43 590 617 577 622 0.71

12 14 0.087 53 4.2 0.1 22 47 624 649 620 656 0.85

13 14 2.4 1.5e+03 -0.4 0.1 22 46 652 676 647 684 0.81

14 14 0.19 1.2e+02 3.1 0.6 22 46 680 704 663 709 0.89

#	of	c-Evalue	i-Evalue	score	bias	hmm coord from	hmm coord to	ali coord from	ali coord to	env coord from	env coord to	acc
1	14	4.2	2.5e+03	-1.1	0.1	26	46	107	127	91	132	0.71
2	14	0.0027	1.6	9.1	0.2	22	46	159	183	150	190	0.86
3	14	0.049	29	5.1	0.1	22	45	188	211	183	218	0.89
4	14	1.2	7e+02	0.6	0.0	22	51	216	245	211	246	0.83
5	14	0.00027	0.16	12.3	0.1	22	47	244	269	231	275	0.88
6	14	0.052	31	5.0	0.0	11	47	288	325	279	330	0.80
7	14	0.034	20	5.6	0.2	21	43	327	349	324	352	0.93
8	14	0.39	2.4e+02	2.2	0.1	13	48	443	482	441	486	0.71
9	14	0.0065	3.9	7.9	0.0	22	52	484	514	481	516	0.87
10	14	0.0045	2.7	8.4	0.1	21	51	539	569	527	571	0.86
11	14	0.23	1.4e+02	2.9	0.1	17	43	590	617	577	622	0.71
12	14	0.087	53	4.2	0.1	22	47	624	649	620	656	0.85
13	14	2.4	1.5e+03	-0.4	0.1	22	46	652	676	647	684	0.81
14	14	0.19	1.2e+02	3.1	0.6	22	46	680	704	663	709	0.89

Sequence Information

Coding Sequence: ATGAACACGATTacctgcgattggtgcttgcaggAAGCGCCGGTACAGCCGACCGAGGAGAGGTTGTGGCGCTTTTGGAAAACCATCAGCAATGAGGATCCGCTAGTAGCGAGTGGCAGGAGCATGTGCGAGAAATGTAAGTCGTGTTACGAGGATTTCTCCACGTACATCGACAGGTGTAAGAGCAACGAGTCCATAATAGATAACGTAATGGTTCCGGGACATGTGAAAGAAGAACCTCTGGTCGACATCGAGTATCATCCCTTGGTTAAAGAGGAACGGTCGTTTTCTGATCGTCCCACGGTCGATAAACGCTTTAAGTGTTCGCGTTGCGGTAAGACTTTCTCCGAATCTTGCACGTTGAAGAGGCACTTTCGCATCCATTCGGGCGACAAACTGTTCAAGTGTACGTACTGCGGTAAGAGTTTCACACAGGTTTCTCACTTGAAGAGACATTCGGACATTCACACGGACGACAAGCCGTTGTCGTGTCCTCATTGCGGTAAGTGTTTCTCCAGTTCTTCCAACTTGAGGACGCACCTCTTGCGTGTCCACACGGGCGATAAACCTTTCGAGTGTCCGCACTGTACTAAGCCGTTCCGATATTCTAGCGACTTGAAAAGCCACTTGCGCACCCATACGGGCGACAGACCTTTCGAGTGTTCGGATTGCGGCAGGACCTTCTCCGACTCGACCACGTTGAAGAGGCACTTTCGTATCCACACGGGGAACAAACCTTTCGGATGCTCGACCTGCGATAAGACTTTCACTCAGTCGGCGAACTTGAAGAGACACTTGCGCCTCCACACCGGCGATAGACCTTTCAAATGTTCACAGTGCGATAAGGCTTTCGTCGAGTCCGGTACCTTGAAGACGCACGAACGTCtccacacgggcgagaagccgtTCAGGTGTTCGCTGTGCGATAAGACTTTCAACGAATCCGCCCATCTGAAGAGTCACCTGCTCATCCATACTGGTGAGAAGCCCTTCGCGTGCTCCCACTGCCATAGACGTTTCGCCAAGTCTTCCAATCTGAAGAGGCACTCACGGGATTCGAGCGACATGAACGTAAccacttgcgattggtgctcgCTGGAGGCTCCGGTGGAAGCAATCGAGGAGaggttatggcgcttctggGGAATAATCAGTAAGGAGAATCCGCCCGTCGCATCCCTCAGCAACATTTGCGTGAACTGCGTCGCCCGTTTCGAGGAATTCTCCGAGTACATCGACAGGTGCAGGAGCAACGAGTCCATAGTGGAGACGGTGCTCACCGCCGGAAGGATCAAGGAAGAACCTCTCGATTACAACCTTAAGGGAGAAACGCCAGGTGAACGTTCGACGGTTACAGAAAAACCTAATACCACTTTCGTATGTTCGTATTGCGATAAAACTTTCACTCGCTCCTCTCATTTGAAGGACCACTTGCGCATCCACACTGGCGACAAGCCGTTCGGTTGTACGCGATGCGCCAAGACGTTCGCCCAGTCGGGCAATTTAAAGAAGCACCTGCGAGTCCACGAGGGCGAGAAGCCGTTCAGGTGTTCTCACTGCGACAAGACCTTCACCACTGCCGGCGATCTGAAGGTCCACTTGCGCATCCACACCGGCGAGAAACCCTTCACGTGCCCGCTGTGCCGTAAAGCATTCACTCACTCGAGCACCATGAAGGCGCACGTGCGCGTCCACAGGGGCGACAAGCCCTACAAGTGTTCGCTGTGCGACAGGGCGTACACCTTCTACGGTTCGTTGCAGCTGCACTCGCGCACCCATACGGGCGACAAGCCGTTCACGTGCCCCTATTGCGATAAGCGGTTCCCGAGTTCTTCCAGTCTGGCTATTCACGTGCGCGTGCACACGGGCGACAGACCCTACGCGTGTGCGCAGTGCGATAAGACCTTCACCCAACAGAACTCCTTGAAGAGGCACCTGCGCGCTCACGCCGGCGACAAGCCTTTCGCGTGTTCGTATTGCGACAGACGGTTCCCCGGCCCGTCTAATTTGAGGGTTCACCTGCGCGTCCACACGGGCGACAGGCCTTTCGCGTGTGCGCAGTGCGATAGGACTTTCACGCAGCCCAACTCGTTGAAGAGGCACCTGCGCGTTCACGAAGGGGACAAGCGATAA
Protein Sequence: MNTITCDWCLQEAPVQPTEERLWRFWKTISNEDPLVASGRSMCEKCKSCYEDFSTYIDRCKSNESIIDNVMVPGHVKEEPLVDIEYHPLVKEERSFSDRPTVDKRFKCSRCGKTFSESCTLKRHFRIHSGDKLFKCTYCGKSFTQVSHLKRHSDIHTDDKPLSCPHCGKCFSSSSNLRTHLLRVHTGDKPFECPHCTKPFRYSSDLKSHLRTHTGDRPFECSDCGRTFSDSTTLKRHFRIHTGNKPFGCSTCDKTFTQSANLKRHLRLHTGDRPFKCSQCDKAFVESGTLKTHERLHTGEKPFRCSLCDKTFNESAHLKSHLLIHTGEKPFACSHCHRRFAKSSNLKRHSRDSSDMNVTTCDWCSLEAPVEAIEERLWRFWGIISKENPPVASLSNICVNCVARFEEFSEYIDRCRSNESIVETVLTAGRIKEEPLDYNLKGETPGERSTVTEKPNTTFVCSYCDKTFTRSSHLKDHLRIHTGDKPFGCTRCAKTFAQSGNLKKHLRVHEGEKPFRCSHCDKTFTTAGDLKVHLRIHTGEKPFTCPLCRKAFTHSSTMKAHVRVHRGDKPYKCSLCDRAYTFYGSLQLHSRTHTGDKPFTCPYCDKRFPSSSSLAIHVRVHTGDRPYACAQCDKTFTQQNSLKRHLRAHAGDKPFACSYCDRRFPGPSNLRVHLRVHTGDRPFACAQCDRTFTQPNSLKRHLRVHEGDKR

Similar Transcription Factors

Sequence clustering based on sequence similarity using MMseqs2

100% Identity: iTF_00392897;
90% Identity: iTF_00392897;
80% Identity: iTF_00392897;