Basic Information

Transcription Factor Domain

TF Family: zf-GAGA
Domain: zf-GAGA domain
PFAM: PF09237
TF Group: Zinc-Coordinating Group
Description: Members of this family bind to a 5'-GAGAG-3' DNA consensus binding site, and contain a Cys2-His2 zinc finger core as well as an N-terminal extension containing two highly basic regions. The zinc finger core binds in the DNA major groove and recognises the first three GAG bases of the consensus in a manner similar to that seen in other classical zinc finger-DNA complexes. The second basic region forms a helix that interacts in the major groove recognising the last G of the consensus, while the first basic region wraps around the DNA in the minor groove and recognises the A in the fourth position of the consensus sequence [1].
Hmmscan Out: # of c-Evalue i-Evalue score bias hmm coord from hmm coord to ali coord from ali coord to env coord from env coord to acc

1 9 0.049 30 5.0 0.0 24 46 101 123 95 127 0.90

2 9 0.011 6.7 7.1 0.0 27 48 131 151 124 156 0.84

3 9 0.035 21 5.5 0.0 18 52 150 184 149 184 0.87

4 9 0.00056 0.34 11.3 0.0 21 52 181 212 179 213 0.88

5 9 0.85 5.1e+02 1.1 0.0 20 44 208 232 205 236 0.84

6 9 4.5e-05 0.027 14.8 0.0 21 45 237 261 226 267 0.91

7 9 0.37 2.2e+02 2.2 0.1 20 44 264 288 261 292 0.86

8 9 0.84 5.1e+02 1.1 0.0 22 49 294 321 289 325 0.81

9 9 0.076 46 4.4 0.0 20 46 320 346 304 352 0.80

#	of	c-Evalue	i-Evalue	score	bias	hmm coord from	hmm coord to	ali coord from	ali coord to	env coord from	env coord to	acc
1	9	0.049	30	5.0	0.0	24	46	101	123	95	127	0.90
2	9	0.011	6.7	7.1	0.0	27	48	131	151	124	156	0.84
3	9	0.035	21	5.5	0.0	18	52	150	184	149	184	0.87
4	9	0.00056	0.34	11.3	0.0	21	52	181	212	179	213	0.88
5	9	0.85	5.1e+02	1.1	0.0	20	44	208	232	205	236	0.84
6	9	4.5e-05	0.027	14.8	0.0	21	45	237	261	226	267	0.91
7	9	0.37	2.2e+02	2.2	0.1	20	44	264	288	261	292	0.86
8	9	0.84	5.1e+02	1.1	0.0	22	49	294	321	289	325	0.81
9	9	0.076	46	4.4	0.0	20	46	320	346	304	352	0.80

Coding Sequence: ATGACTTATGTGTTAGGGGGTCCAGCCTTGGCATCCCGTAAGGATATCTGCGAGAAGTGTAAGTCTTGCTATGAGGAATTCTCGGTATATGTAGAGACTTGCAAGGCCCATGCGTCCATCGTAGACAGGGCACGGACTCCTGGGCAAGTCGAAGACGGACCTTCGATCGATGCCGTGTGTTTCCCGTCAATCaaggaagaaattttaacgGAAGATAAGTCGGGTCAGTCTTTTAAGTCACCACGCCGTGATGAGGTGTATGCTGCGCCCGGTGATTCGGGAAAGCGTATGCTCGTTCGTCCTTATGAATGTTCCATATGTAATAAGGCTTTCGCTTCGTCCGGTAATTTGAAgacgcacatgcgcattcatacaggtgagtCTTTTCGATGTTTCACCTGTGATAAGGTTTTTACTCAGTCGGGTGCTTTAAAACGACACCTGCGCCGccatacgggcgagaagccctttaaatgttccgtcTGCGGTAAGAGTTTCAGCGAATCTGGTAGCTTGAAGtcgcacatgcgccttcacacGGGCGAAAAGCCTTATAAATGTTCGATCTGTAACAAATCGTTTACTTTGTCCGGTAATTTGAGGAAGCACGTGCGCGTCCACGCTAGCGAAAAGCCCGTTAAATGTTCACACTGCGACAAGGCTTATACCCACGCTGGTGATTTGAAAAACCATATGCACACTCATACCGGCGAGGAACCCTACAAATGCCCCGTTTGTACTAAGACTTTTACTTTGTCTCGTAACTTGAAGACGCACCTGCGCGCGCATACGAGCGAAAAGTCCTTCGAATGTTCCATATGTACTAAGACTTTCGCTGTGTGTGGTAATTTGAAGACGCACATGCGCACTCATACGGgggaaaagtcttttaaatgcaccgcctgtaataaggcttttagtCAAGCTGGTGGcgtgaaaaggcacatgcgcgtTCACACAGgagagaagccttttaaatgttccatctgtaataagccCTACGCTTGGTCTGGTGATTTGAAAAAGCATATGCTTGTACACGCAGGTGAAAAACCTTTCTAA
Protein Sequence: MTYVLGGPALASRKDICEKCKSCYEEFSVYVETCKAHASIVDRARTPGQVEDGPSIDAVCFPSIKEEILTEDKSGQSFKSPRRDEVYAAPGDSGKRMLVRPYECSICNKAFASSGNLKTHMRIHTGESFRCFTCDKVFTQSGALKRHLRRHTGEKPFKCSVCGKSFSESGSLKSHMRLHTGEKPYKCSICNKSFTLSGNLRKHVRVHASEKPVKCSHCDKAYTHAGDLKNHMHTHTGEEPYKCPVCTKTFTLSRNLKTHLRAHTSEKSFECSICTKTFAVCGNLKTHMRTHTGEKSFKCTACNKAFSQAGGVKRHMRVHTGEKPFKCSICNKPYAWSGDLKKHMLVHAGEKPF

Sequence clustering based on sequence similarity using MMseqs2