Basic Information

Insect: Cryptocephalus primarius
Gene Symbol: Baz2b
Assembly: GCA_963576515.1
Location: OY754946.1:1565600-1581227[-]

Transcription Factor Domain

TF Family: MBD
Domain: MBD domain
PFAM: PF01429
TF Group: Unclassified Structure
Description: The Methyl-CpG binding domain (MBD) binds to DNA that contains one or more symmetrically methylated CpGs [2]. DNA methylation in animals is associated with alterations in chromatin structure and silencing of gene expression. MBD has negligible non-specific affinity for DNA. In vitro foot-printing with MeCP2 showed the MBD can protect a 12 nucleotide region surrounding a methyl CpG pair [2]. MBDs are found in several Methyl-CpG binding proteins and also DNA demethylase [1].
Hmmscan Out: # of c-Evalue i-Evalue score bias hmm coord from hmm coord to ali coord from ali coord to env coord from env coord to acc

1 1 4.8e-16 1.6e-12 47.0 0.0 5 75 684 755 681 757 0.89

#	of	c-Evalue	i-Evalue	score	bias	hmm coord from	hmm coord to	ali coord from	ali coord to	env coord from	env coord to	acc
1	1	4.8e-16	1.6e-12	47.0	0.0	5	75	684	755	681	757	0.89

Sequence Information

Coding Sequence: ATGGACAAGGAAAATGGTAAGGGCAACGAAGGAAATTCCGGCTCTAGCAAAGTATCCAATCCGCAGGACACCGCCGCGTCCCTGCTCGACGCGGCCAGTCTCTTCGGAGCTTATTGGCCGCGGGGCGAGGCGGCGAACCTGTTCGCCGCCGGGGGCGGCTTCGCGCTTCCGCCCCACCCGGGGCTGCCCTTCGGGATGCTGCCGCCCGGGGCGGCCTCCGGACGGTCCTACGCCCCGACGGCGACGTCGTCGGCCGCCTACAACGCAGCCGCCTACACGAACACGCTGTCGGTCGCCGCGAGCCAGGCGGCCAGCCTCGGCATACATGCAACTAGCGCGGCATGGTGGTCGATGGCCTCTCACCTGGCAGCTCAGGACTACCTGGCGAGACTGCAGGCGTCGGGCCTAAACCTCACGGGCCTGGGAAACCCCGCTGACCCGTACTCGACCCTCGGCCTGCCGTCGCTCTCCACGCATCACAAGTCGAAGAACTCCAAGGGCTCGTCTTCATCGAGGTCGCAGCTCAACTCGAAGCAATCGTCGTCGGACTCGGTCAAGTCCACGGCCCAGAACTCCTCGTCGACGTCGACGCGTctctcgtcctcctcctccacgATCACCTCCTCGTCATCGTGCCACCTTCCGTCACAGACCTCCCTCAAGTACTCGTCGGGCCTGACGATCAAGCCGACGATGAAACTGCCTCCTTCGGGCGAGAAACAGCACCGCGGCCAGAAGGGCGCATCGTCGAACTGCGACCTGAATTACCTGCCCGGCAAACAGAAGACTGCCAGTAGCAACTCGAACGCGAACGTCACCAGCTCGAGGTCGGGCTCGCCCTCGCCGAGCATCTTCAGCAGCCCGCTGAGCCTCGCCAGCAACAATGGCGGCTCGTCCGAGAAGGTGAACGAGCAGGGCGGAGGGAGCGGCGCCGGACTGCCTGCCAGTATTCTTAGTGCCGCCCTTGAAGGCAGCAGTGATCCTAATTCAATTTTGGGCGGTGTTAGGTTACCACCCGACACAGAGATCATCAAGTACACATCCTCGATAGTCGGGCCTAAGATACCCGGCACGACGAACAGGGGCAGGAAGAAGACGATCTCGCTAGATCCGCCCTCGGTGAGCGTCCACCCGTCTCACTCCAGCACCGGGCTGCTCATCGAACGTACAACGAAACGACCCAAGCTGACGGAGCAGGAGCTCTCGCCGCCGTCGACGCCGTCCGGGGACAGGGTCGAGGTGATCAAGCTGCCGGCGACGAACGGCACCCCGGCCGGGCTCGCGTCGACCTACAACAGCGCCGATTCCGGCAGCGAGGCTCCACTCAACCTCTCGCTCAAGCCGAGCACCTCGAGCTGCAGCACGTCGTCCCTCACGTCCCTCAGCAACATGTCGGCCAGTATCGGAACGGATCGAATATCCCGCAGGAAGCCGGGCCCGAAGCCCCGGCGGGTGGTCCCGTCCTCGACGGCGTCCTCGCCGTCGCCGTCCCACGGCGCTCAGGCGGCGGCGCCCCCGGGGGCGCCGAGCGCCTCTCTCAACCAGCTGTTCGCGCAGGCGGACTCGCCGAGGCCCCCTAGTCGGAACGAGGGCTCGGACGGCGGCAGCTCGACGTCCTCGACGTGCGCCTCTTCGTGCACGATAGCCGGGGGTAGCACGACGATCAGCCCCGTCGGCCAGAAGGAGGGCAGGCCGAGGAACCTCGGCAGAGGCGTCAGCAAGCCGAAGAAGAACACCGTCGCTTCGTTGCTCGCGCAGAGCAGGGCGTTAGGTATAAAACCGATGCCGATGCTGGACCCGAGCATCTCTATGAACCAGCAGATGAATCTGCTCAAGTCGAACATCCTCGCCGCCCAGCAGTACATCCAGGAGGTAGGCGGCGACGAGAAGACCCTCAACAAATTCCTCCAGGATAGGTTAAGGGGTACGCTCAGTGATTCCAGTACGGTAGACGCGACGTCCGATTCAGATAACTTAACTGATTCTAATTATACTGATTCAGAGATGGAAGTCGAAGTCGCCGCTAAGAAGCAGAAGCAGTACGATGAAAGGCTGCTCAGGGTACCATTAGAAAAAGGTTGGAGACGGGAGACAATAATCAGGGGCTTGACCAAGAACGGTGGGATCAAGGGGGACGTTACCTATGTCGCCCCAGAGTCGTCCAATAAATTCAAGCAGATGTCCGACGTGACACAGTACCTGGAGTACCAGAAGAGCATCGAACTGTCAAAAGATAACTTCACATTCAGCTCCAGGGTGATAATAGGAGATTATCTCCAGCCGGTTCCCCTCGAAATGCAAGCCGACGGTCTGGAGTTCATACATCTCAGTGAGGAGGATGTACTACGAAGACTGGACGAATTGAAATCGTCGATGCGCACTAGCCTGCCGGTGGAGCAGCGTATCGAGATGGCTCGCAAGCAGCAGGCGGCGAGGGCCGCGGCGAGACTCGACAGGGAGCAGGCGAGGCTCACGAAGGAGCTCGAGAGGAGCGAGAGGCAGGAGCAGGCGAGGCGCGAGAAGGAGGCGAGGTCCCAGCAGATGCTCGAGGCAAAGAGAAAAAGACAAGAAGAGATGGAGAGGCATAAGCAGGAAGAGCAACAACGAAAACAACAGGAGAGAGAACTGAAAAGACAGCAGGCCGCGTTATTGAAGGAACAGATGTACATACAGGAGATCAGTAAACAACGAGAAATGCTCTACACTGTTGAGTTGGAGAAGGAGCGTAGGAGGCAGCACATGGCGCTGGTGAAGTCGCTGGAGAGCAGGCGGAAGCTCGAGGAGCGCGAGCGGAAGAAGCAGCAGCTCCTCGCCGAGAAGCAGGCGAACAAGGAGAAGAAGCTCGAGCAGCGCAGGCAGGAGCTGGAGATCCTCGCCGAGATCCGGAAGCCGTGCGAGGACCTCGAGCTCGAGCAGCGCGAGCTGCCCGAGTACGGGCGCGTCCCGGGGCTGAGGCTGCCCGGCAAGGCGTTCGGCGAGGCGCTGATGGTGTTCGAGTTCCTCCACACGTTCGGCGAGACGCTGGGCTTCGACATGGAGTCGCTGCCGACGCTCGACTCGCTCCAGCAGGCGCTCATGCCGAACGAGCACACGCTCGAGGCCGAGGAGGAGCTGTTCTCGGTGATGACGCACCTGCTGGTGTGCGCGATCGAGGATCCGGGCATCCCGAACCCGGCGAGGTACACGACGATACTCGGCCAGAGCCTGCGCACGGCCGACATCACCCACGCGAACCTCTCCGAGATACTCAGGATATACCTGTACGCTAACGCGACCGGCGAGGTCAAGGCGCTCACGGGGGTGCACTTCGAACGGGACAGGGAGAAGCGCGTCGCCGATCACCACCAGAACGAGGACGAGATGCAGGTGACGCAGATCGGCAAGAACGCGCAGTACTACGAGCACCTCCACAACAACCCGACGTACAAGCTCTCGGACCTGCTCAAGGACAAGCCCTTCATGGCGCTCTCGCCGAGCAACAAGGCCGAGATACTCGCCTACGTGTGCAACGAGCTGCTGCAGAACAAGGCGGTCATCAGGCAGATCGAGAGCTCGCTGGAGACGGTCGCGCAGCAGAAGAAGGAGAAGTGGCTGCTCGACATGAAGATCAGGAAGTTGAAGATGTTACATAACAGAAAGCTGAGGGCCGAGGCGGTCGAGAGGGTCCAGACGAAGATCGACGGCGAGGACTCGAACGTCGACTCGCCGTCCCTGCACAAGGACGATCTCCTCGACGAGGACGAGAACGACATCAGCGAGAACGAAAGCGTCGGCACGCAGCCGGAGGAGGAGGAAGACATCAAGCTGTCCTGCGAGGAGCTTTCGAAGAAACTGGAGAAGCTCATCCGTCAGTCGGACGCCCACCTGAACTCGTTGAACACGGCGACGTGCCAGCTGAGGGCGACCTGCTTCGGCCAGGACCGTTTCCATCGGCGCTACTGGTCGTTCCCGAAGACGGGCGGCGTCTGGGTCGAGGCGATGGAGAGCGCCGACCCGGACGAGCTCGAGGAGCAGTCTCGCCTCGACAACCTCGAAATATCCAACAAGGGCATCAAGTGCCTCAACGACCTGAACAACATACTCGACAAGGTCGAGAGGATCAACGACAGCACCGTCGACAAGGAGGTGAGCAGCATCGTCGACAGGATGGACGGTCGGGCGGCCGACGACGAGGAGTACGAAGAGGATGACAACGAGCACCGGAAGACGCCGAACAGATCGGCCGGCGTGGCGTTCGAGAACGGCGAGGCGGTGCTCGACAAGAACGAGCGCAACCTCGCCGAGCTGAAGAAGAGCGTCGACGACATAGTACAAAACCTCGAGAGGAACCTCGAGATGGAGAAGCAGCAgaggaaggaggaggaggaagagggaTCTCAAGTGACAGCGAATCACGTCAAGACGGAGGAAGAAGAGGCGACGGCCGAACCGTTCGGCAGCAAAAAGTTCAACCTGTTCGAGCGTCTCGGGCAGTGCATGGAGCGCGAGAACAAGACCGAGGAGGACCTCAAGGCCGAGGTCAAGGCGGAAGTGAAGGAGGAGCTCAAGAACGAGATCTTGAACGAACTCAAGTCGGAGGCGAGTATCAAGGCCGAAATGAAGAACCCCGGGGAGGAGTCGGAACAGAAGTGGTTCAGCATACTGGACAGAGAAGGTGTCACCTGCGACGGGATACACCTCACCTCGGGTCAGAACGGCATAGGCAGTTGCGGCAGGGACATCACCGAGCTGAAGATCCCGGTATTCCCGCCGCCGAACTCCAACTACCACCACAACTGTGATAGCCCGGCTCCGTTGCAGATGACGCACGAGGAGAGCGTCCAGCTCGAGCACATAAAGAAGCACGGCATGCAGCCGCCGCTGGAGAGGAGACTCGTGCCTTCCGACAAGCAGTACGGCTGGTGGCGGATCGGCGACACCTCCCAGCTGAGGGAGGTGCTGGACAAGCTCCACGTCAGAGGTGTGCGGGAGCGTGAACTGAAGAGATCGTTCATCAACGTCATGCAGACGATGTACGAAGGACAAGGCAGGCTGGTGATAGAGGAAGGTTTTAAGGAGCTAACGGAGCTGAACGGTGAGATTTTGGATCCGGTGACGTACGTCCCCGGGGGCGCCCCGGCGCCCGATTTGCCGGGAGCCTGGAACGCTTCCATAGCGCACCGGGTCGACTTGTCCCTCTTGGAACAGGTCGAAGCTCTCGAGGATAAAGTTGCAAACGCCAGCATGCAAGTAAAGGGCTGGAAGATACCCAATAGGGACTCTTCGGACGTAGCTTACAAGCACGTCGTGCCTCTGGTTAAACAACGTTTAGCCTCCTTGGAACAGAACATCGAAAGACGGTACCTCAAGCCGCCCCTCGGCGTCAATACGGGTGACCCGAACCTGGCGGCGATAGCCCAGGAGGCGGCGAGCGGGGGCTCTTGCGGGACcgcctcgtcgtcgtcgtcgtcgtcgacaTCGAACGCAGCCTCGACCTCGTCGTCCGCCTCGACGTCGGCCTCTTCCTCCTCGGcctcggcggcggcggtggcggtcGCGCCCCAGCCGCTCCCGAGCCTCGACGACGTCCCGAAGGGCCTGGCGACGTGGCGGGAGGCGGTCAACCGCTGCCAGACGTCCGCCCAGCTGGCGATGTGCCTCTACCAGCTGGAGTCGTCGATAGCATGGGACAAGAGCATCATGAAAGCTGTGAGCGCCTTTAATAAACAGACAGCCCGCAAATATAACAGCAAGCTGAGTAACTGCCAGTTCTGCCACAGTGGCGACAACGAAGACAAATTGCTGTTATGCGATGGCTGCGATAAAGGCTACCACACTTACTGCTTCAAACCTAAGATGGAGAACATCCCCGACGGGGACTGGTACTGCCATGAGTGCATGAACAAGGCGACGGGGGAGCGCAACTGCATAGTTTGCGGCAAGAAGGCCTCCACGTCCGGCACCAAGTTGGTACTGTGCGACCTGTGCCCCCGTTGCTATCACACGGACTGCCTCCAGCCGCCGTTGGGCAAGGTGCCTAGGGGCAAGTGGTACTGCTCGAATTGCATAACGAAGAAACCCCAGAAGAGGCCAGTGAGGAAGAACCACAACAATAAGGTCGCCAGGGACAGCGAGTCTTCCGACCACCCACCGTCTAGTCCGGCGCCGTCGCACAGTTCGGCTACTACGAACGAGGACGTCCCCTCGTCGGCGAACTGCACGCAGAGCGACGTCTCGAACTCGAGCCTCGCGAACGTCGGCTCGCCGTCGACGCCGCAGGCCGTCGCTGCGGCCGCCGCCTTCGCGAAGAAGGAGAACAAGACGAACAAGAAGCTGCTGAAGGAGCTCGCGCCCTGTAAGGCGCTCCTCGAGGATCTCGAGTGCCACGACGACGCGTGGCCCTTCCTGCTGCCGGTGAACACGAAGCAGTTCCCGACCTACAAGAAGATCATCAAGGTGCCCATGGACCTGTCGACGATCAAGAAGAGGTTGCAGGACGTGCATTACAAATCTAAAGAGGAGTTTTGCGCGGACGTGAGGCAGATCTTCAACAACTGCGAGACGTTCAACGAGGACGACAGCCCCGTAGGCAAGGCGGGCCACTGCATGCGACAGTTCTTCGAGGCGAGGTGGAACGAGATCTGCTCGTCGCACAGTTGA
Protein Sequence: MDKENGKGNEGNSGSSKVSNPQDTAASLLDAASLFGAYWPRGEAANLFAAGGGFALPPHPGLPFGMLPPGAASGRSYAPTATSSAAYNAAAYTNTLSVAASQAASLGIHATSAAWWSMASHLAAQDYLARLQASGLNLTGLGNPADPYSTLGLPSLSTHHKSKNSKGSSSSRSQLNSKQSSSDSVKSTAQNSSSTSTRLSSSSSTITSSSSCHLPSQTSLKYSSGLTIKPTMKLPPSGEKQHRGQKGASSNCDLNYLPGKQKTASSNSNANVTSSRSGSPSPSIFSSPLSLASNNGGSSEKVNEQGGGSGAGLPASILSAALEGSSDPNSILGGVRLPPDTEIIKYTSSIVGPKIPGTTNRGRKKTISLDPPSVSVHPSHSSTGLLIERTTKRPKLTEQELSPPSTPSGDRVEVIKLPATNGTPAGLASTYNSADSGSEAPLNLSLKPSTSSCSTSSLTSLSNMSASIGTDRISRRKPGPKPRRVVPSSTASSPSPSHGAQAAAPPGAPSASLNQLFAQADSPRPPSRNEGSDGGSSTSSTCASSCTIAGGSTTISPVGQKEGRPRNLGRGVSKPKKNTVASLLAQSRALGIKPMPMLDPSISMNQQMNLLKSNILAAQQYIQEVGGDEKTLNKFLQDRLRGTLSDSSTVDATSDSDNLTDSNYTDSEMEVEVAAKKQKQYDERLLRVPLEKGWRRETIIRGLTKNGGIKGDVTYVAPESSNKFKQMSDVTQYLEYQKSIELSKDNFTFSSRVIIGDYLQPVPLEMQADGLEFIHLSEEDVLRRLDELKSSMRTSLPVEQRIEMARKQQAARAAARLDREQARLTKELERSERQEQARREKEARSQQMLEAKRKRQEEMERHKQEEQQRKQQERELKRQQAALLKEQMYIQEISKQREMLYTVELEKERRRQHMALVKSLESRRKLEERERKKQQLLAEKQANKEKKLEQRRQELEILAEIRKPCEDLELEQRELPEYGRVPGLRLPGKAFGEALMVFEFLHTFGETLGFDMESLPTLDSLQQALMPNEHTLEAEEELFSVMTHLLVCAIEDPGIPNPARYTTILGQSLRTADITHANLSEILRIYLYANATGEVKALTGVHFERDREKRVADHHQNEDEMQVTQIGKNAQYYEHLHNNPTYKLSDLLKDKPFMALSPSNKAEILAYVCNELLQNKAVIRQIESSLETVAQQKKEKWLLDMKIRKLKMLHNRKLRAEAVERVQTKIDGEDSNVDSPSLHKDDLLDEDENDISENESVGTQPEEEEDIKLSCEELSKKLEKLIRQSDAHLNSLNTATCQLRATCFGQDRFHRRYWSFPKTGGVWVEAMESADPDELEEQSRLDNLEISNKGIKCLNDLNNILDKVERINDSTVDKEVSSIVDRMDGRAADDEEYEEDDNEHRKTPNRSAGVAFENGEAVLDKNERNLAELKKSVDDIVQNLERNLEMEKQQRKEEEEEGSQVTANHVKTEEEEATAEPFGSKKFNLFERLGQCMERENKTEEDLKAEVKAEVKEELKNEILNELKSEASIKAEMKNPGEESEQKWFSILDREGVTCDGIHLTSGQNGIGSCGRDITELKIPVFPPPNSNYHHNCDSPAPLQMTHEESVQLEHIKKHGMQPPLERRLVPSDKQYGWWRIGDTSQLREVLDKLHVRGVRERELKRSFINVMQTMYEGQGRLVIEEGFKELTELNGEILDPVTYVPGGAPAPDLPGAWNASIAHRVDLSLLEQVEALEDKVANASMQVKGWKIPNRDSSDVAYKHVVPLVKQRLASLEQNIERRYLKPPLGVNTGDPNLAAIAQEAASGGSCGTASSSSSSSTSNAASTSSSASTSASSSSASAAAVAVAPQPLPSLDDVPKGLATWREAVNRCQTSAQLAMCLYQLESSIAWDKSIMKAVSAFNKQTARKYNSKLSNCQFCHSGDNEDKLLLCDGCDKGYHTYCFKPKMENIPDGDWYCHECMNKATGERNCIVCGKKASTSGTKLVLCDLCPRCYHTDCLQPPLGKVPRGKWYCSNCITKKPQKRPVRKNHNNKVARDSESSDHPPSSPAPSHSSATTNEDVPSSANCTQSDVSNSSLANVGSPSTPQAVAAAAAFAKKENKTNKKLLKELAPCKALLEDLECHDDAWPFLLPVNTKQFPTYKKIIKVPMDLSTIKKRLQDVHYKSKEEFCADVRQIFNNCETFNEDDSPVGKAGHCMRQFFEARWNEICSSHS

Similar Transcription Factors

Sequence clustering based on sequence similarity using MMseqs2

100% Identity: iTF_00391929;
90% Identity: iTF_00391929;
80% Identity: -