Basic Information

Transcription Factor Domain

TF Family: zf-GAGA
Domain: zf-GAGA domain
PFAM: PF09237
TF Group: Zinc-Coordinating Group
Description: Members of this family bind to a 5'-GAGAG-3' DNA consensus binding site, and contain a Cys2-His2 zinc finger core as well as an N-terminal extension containing two highly basic regions. The zinc finger core binds in the DNA major groove and recognises the first three GAG bases of the consensus in a manner similar to that seen in other classical zinc finger-DNA complexes. The second basic region forms a helix that interacts in the major groove recognising the last G of the consensus, while the first basic region wraps around the DNA in the minor groove and recognises the A in the fourth position of the consensus sequence [1].
Hmmscan Out: # of c-Evalue i-Evalue score bias hmm coord from hmm coord to ali coord from ali coord to env coord from env coord to acc

1 6 0.5 9.3e+02 0.4 0.2 26 47 117 138 100 143 0.82

2 6 0.038 71 3.9 0.0 22 47 141 166 138 171 0.84

3 6 0.00043 0.8 10.2 0.0 22 45 169 192 165 199 0.86

4 6 0.0047 8.6 6.9 0.1 21 45 196 220 192 223 0.87

5 6 0.026 49 4.5 0.0 21 43 224 246 212 252 0.82

6 6 0.0011 2 8.9 0.7 26 45 313 332 300 335 0.89

#	of	c-Evalue	i-Evalue	score	bias	hmm coord from	hmm coord to	ali coord from	ali coord to	env coord from	env coord to	acc
1	6	0.5	9.3e+02	0.4	0.2	26	47	117	138	100	143	0.82
2	6	0.038	71	3.9	0.0	22	47	141	166	138	171	0.84
3	6	0.00043	0.8	10.2	0.0	22	45	169	192	165	199	0.86
4	6	0.0047	8.6	6.9	0.1	21	45	196	220	192	223	0.87
5	6	0.026	49	4.5	0.0	21	43	224	246	212	252	0.82
6	6	0.0011	2	8.9	0.7	26	45	313	332	300	335	0.89

Coding Sequence: ATGCTTACGTGCGGCACCAGCAAACAGGGCAATCCGCCTTGTGTCCAGCCAACCTCTGCGAGCGCCTACTTACAGGGCGATCCACCTCGTTCCCCGGACGACCTCCGCCTCCCGCACGCATCCGGCGGCTTCCACGACCCGCTGGTCGGATCGCTGAGGAATATCTGCCAGCGATGTACGTCGCGCTACGAACGCTTCCATGGCTACATTGACCGGTGCAAGAGCAACGAGACCATCGTCGAGTCGATCCTCGCCGCCGTCACGATCAAACCTGAACCACAGATCGACACCGAGTACCACCACCCGATCAAGACGGAGGGATCGACGCTCGCCGATCCCTCCCGACCGGAgtgcccgcactgcggcaagaccttcgcccgttcgagcgcgctcctcgtccacctacgcctccatacgggcgagagaccgttcgagtgcccgcagtgcggcaagacgttcgcccgttcgaacgacctcaacctacacatgcacgtccacacgggcgacaagccgttcgcgtgtccgcactgcgacaagacgttctcgcagtcgtcgaacctgaagagccacgtgcggacgcacacgggcgagaaaccgttcgagtgtccgcactgctacaagacgttcgctcggcccggcacgttgaagacccatctaccgatacacacgggcgagaggccgttcggttgctcgaagtgcgacaagacgttcgcccggtccggcaacttgaggagccacgagcgggtccactggggcgaggagcgtttcgaatgtacctactgcgacaggacctacgctcacttcagtacgttgaagatccatctgcgggcgcactccggcggtgaacctttcaagtgttcgagctgcggcgagaccttcgcctcattcgatcgtctcaaggatcacttgcgggttcacgacgacgcgaagcgtttcaagtgttcacagtgcgataaggccttcactcaatcgtgtaacttgaggaggcacttgcggaaacataaccagtga
Protein Sequence: MLTCGTSKQGNPPCVQPTSASAYLQGDPPRSPDDLRLPHASGGFHDPLVGSLRNICQRCTSRYERFHGYIDRCKSNETIVESILAAVTIKPEPQIDTEYHHPIKTEGSTLADPSRPECPHCGKTFARSSALLVHLRLHTGERPFECPQCGKTFARSNDLNLHMHVHTGDKPFACPHCDKTFSQSSNLKSHVRTHTGEKPFECPHCYKTFARPGTLKTHLPIHTGERPFGCSKCDKTFARSGNLRSHERVHWGEERFECTYCDRTYAHFSTLKIHLRAHSGGEPFKCSSCGETFASFDRLKDHLRVHDDAKRFKCSQCDKAFTQSCNLRRHLRKHNQ

Sequence clustering based on sequence similarity using MMseqs2