Basic Information

Gene Symbol
ZNF219
Assembly
GCA_946251935.1
Location
CAMIUL010000163.1:689473-694243[+]

Transcription Factor Domain

TF Family
zf-GAGA
Domain
zf-GAGA domain
PFAM
PF09237
TF Group
Zinc-Coordinating Group
Description
Members of this family bind to a 5'-GAGAG-3' DNA consensus binding site, and contain a Cys2-His2 zinc finger core as well as an N-terminal extension containing two highly basic regions. The zinc finger core binds in the DNA major groove and recognises the first three GAG bases of the consensus in a manner similar to that seen in other classical zinc finger-DNA complexes. The second basic region forms a helix that interacts in the major groove recognising the last G of the consensus, while the first basic region wraps around the DNA in the minor groove and recognises the A in the fourth position of the consensus sequence [1].
Hmmscan Out
# of c-Evalue i-Evalue score bias hmm coord from hmm coord to ali coord from ali coord to env coord from env coord to acc
1 4 0.0011 2 8.9 0.1 26 52 108 134 104 136 0.87
2 4 0.0011 2.1 8.8 0.0 21 48 145 172 141 176 0.87
3 4 0.01 18 5.8 0.1 21 46 173 198 170 204 0.85
4 4 0.0024 4.5 7.8 0.0 21 44 201 224 194 228 0.88

Sequence Information

Coding Sequence
ATGAGCGACGCCATGAAGGCGACTACTTGCGATTGGTGCTTGTGCGAGGCACCGGTTCGCACGATCGAGGAGAGGTTATGGGGCTTCTGGGGGGTAATCAGCAATGAAGCGCCGCTCTTGGAATCCCTGAGAGACATCTGCGACGGATGCACGGCGCGCTACGACGGATTCTGCAAGTACATTGAAAGGTGTAAGAGCAACGAGTCAGTTGTCGAGAAGGTTCTCTCCGTCGGGACTGTCAAAGATGAACCGATGATTGACATTGAGTACAACCCGTTAACCATTGAGGGGGATGGAccggctgatatgggcgttcagctggcgtgttcgtgctgcggcaagatcttcggcaattcgaacaacctgaagaggcacctgcgggtccacaccggcgagaaacctcacttgaacatccacgtgcgcctccacacgggcgagaaaccgttcaagtgccctcagtgcgacaaggccttcactcagtccggcagcctgaacagccacctgcgcgtccatacgggcgagaagccgttcaagtgtccacgctgcgacaaggcgttcgccgagtccgcccacctgaggagccactcgcgcatccacactggcgagaaaccgttcaagtgtcccgagtgcgacaaggccttcgcccagtcgtactacctgaagagccacctacCGATTTTCGGGGACGACGGACTACGTGCCGAACGAAGGTCTCCGGATTTCGTCCAGTCGTTGGGTTTCGTGGGAACCCCCGCGAAATGGGAAGGCCCGGAGGAATCGTCACGGAGATTCGGCAAAACGGGAAAAAGGAGGACACTTCTGATTGTTGACGTGTCGCGCACGGTCGATATTTAG
Protein Sequence
MSDAMKATTCDWCLCEAPVRTIEERLWGFWGVISNEAPLLESLRDICDGCTARYDGFCKYIERCKSNESVVEKVLSVGTVKDEPMIDIEYNPLTIEGDGPADMGVQLACSCCGKIFGNSNNLKRHLRVHTGEKPHLNIHVRLHTGEKPFKCPQCDKAFTQSGSLNSHLRVHTGEKPFKCPRCDKAFAESAHLRSHSRIHTGEKPFKCPECDKAFAQSYYLKSHLPIFGDDGLRAERRSPDFVQSLGFVGTPAKWEGPEESSRRFGKTGKRRTLLIVDVSRTVDI

Similar Transcription Factors

Sequence clustering based on sequence similarity using MMseqs2

100% Identity
iTF_00392171;
90% Identity
iTF_00392171;
80% Identity
iTF_00392171;