Cdil026947.2


Basic Information
Transcription Factor Domain
Sequence Information
Similer Transcription Factors

Basic Information

Insect
Creontiades dilutus
Gene Symbol
RHOBTB1
Assembly
GCA_031894815.1
Location
JAVIWC010005959.1:3540638-3565829[-]

Transcription Factor Domain

TF Family
BTB
Domain
zf-C2H2|ZBTB
PFAM
PF00651
TF Group
Zinc-Coordinating Group
Description
The BTB (for BR-C, ttk and bab) [6] or POZ (for Pox virus and Zinc finger) [1] domain is present near the N-terminus of a fraction of zinc finger (Pfam:PF00096) proteins and in proteins that contain the Pfam:PF01344 motif such as Kelch and a family of pox virus proteins. The BTB/POZ domain mediates homomeric dimerisation and in some instances heteromeric dimerisation [1]. The structure of the dimerised PLZF BTB/POZ domain has been solved and consists of a tightly intertwined homodimer. The central scaffolding of the protein is made up of a cluster of alpha-helices flanked by short beta-sheets at both the top and bottom of the molecule [2]. POZ domains from several zinc finger proteins have been shown to mediate transcriptional repression and to interact with components of histone deacetylase co-repressor complexes including N-CoR and SMRT [5, 3, 4]. The POZ or BTB domain is also known as BR-C/Ttk or ZiN.
Hmmscan Out
# of c-Evalue i-Evalue score bias hmm coord from hmm coord to ali coord from ali coord to env coord from env coord to acc
1 3 6.7e-06 0.003 19.0 0.0 10 44 263 296 257 315 0.83
2 3 0.0031 1.4 10.4 0.2 51 100 401 457 385 466 0.76
3 3 1.2e-17 5.5e-15 56.8 0.0 5 107 490 591 485 594 0.92

Sequence Information

Coding Sequence
ATGGATAATACTGAACATCACCAGGAGCTTGTCAAGTGTGTGGTGGTCGGTGACACGGCAGTGGGTAAAACTCGTCTCATCTGCGCGCGCGCCTGCAACAAGCAGCTTTCCCTGTCACAGCTCCTCACTACCCATGTGCCCACAGTCTGGGCAATAGATCAGTACCGGATCTACAAAGATGTGCTCGAACGATCCTGGGAAGTTGTTGATGGAGTGAACGTGTCCCTGAGGCTTTGGGACACTTTTGGCGACCATGAGAAAGATAGGAGATTCGCGTACGGCAGGTCCGACGTGGTTTTACTATGTTTCTCGCTCGCTTCCCCCAATTCGCTCCGCAACTGCAAAGCGATGTGGTACCCGGAAATCCGAAGGTTCTGTCCCAACACGCCCGTCATCCTCGTCGGTTGTAAAAATGACTTGAGGTTCATGTATAGGGATGAAGCCTACCTCGACTTCTTCAGGGAAAGAAGTCCATTCTTGAGgGCGATCAGAAAGTCGGACCTAGTCATGCCAGATCAAGCTAGGAGCATCGCTCGTGAGCTTGGTGTCACCTACTATGAAACTTCTGTTCTCACTTACTATGGTGTGAATGAAGTTTTCGAAAATGCTATTCGAGCGGCGTTGATTGCTCGGAGACAACAGCGTTTCTGGATGACCAACTTGAAGAAAGTTCAAAGACCTCTTCTTCAAGCACCATACTGCCCACCTAAACCAGTCGCTAGACCTGTTCAGGTGTGTGCCTCCACATTTGACGACTCGCTGCGCTGGTTGTTGACTAATCTTCCACACACGGACGTCATTTTCGTAGTGGGGACTATTTGTATTCCTGCCCATAGGTTTATGCTGGCTGCTGCTTCCCCTTCATTGCAAAGGTTACTGTGCACTGATCTTACAGGGGAACTCAACACTAGAAGCGCTAGCGAATCCTCGATGGTGTCATCATTTGGAGAAGCCACTTCAGGCGATTTCAATGAAGACACCGAATTCCTTATCAGGGTAGAAAAGCCATCCAGGGGAGGAGTGTGGGAGCAGCTGAAGAGGCGTTCTTCCTGCCAAGTGTTGACGTCAGCTTGCAATAACTCTCCCAACCAACGAGTTTGTGCCAATCGTGAACTTAATCATCCCGCGTTTTCGTCGATAAGAGTTCAACAGGTAGAAGATATGGACACACAAGGAAGATTGACAGCGTCCTTGCAGACTGTGATAACGTTGAGTAAGCTGGTGACACCACAAGCTATGCAACAAACCCTCATGTTTCTGTACACAGGAACCATAGACTCCAAATTTACACAGATTCAGaatTCTTCTCTCGGACTTTTAATGGAAATCCGGCAAGCAGCTGAGTTCATGGAGCTGCCAGAACTTCAAGTTTACGTTTCCAATATGCAGTCCCATGAAGAGTTTTTAAACCCAGAACTCAAACAACGCTATAAACAAGCCGTTCGAGTTAGGCTCAATGAGCTTTGCCTCAGCCAAGGTCTGTTTGCTGACGTCATATTCCAACTTGATGATGGCTGCATACCTGCTCACAAGCCCCTCCTCATGGCGAGATGTGACATGATGAGAGCCATGTTCTCTGGTGACTTCAGAGAAGGTTCGGCTAAAGTGATTCACTTCCCAGGTGTGAAATGTGAGGTGTTCCGGGTCCTTCTATGCTACTTGTACTGTGACGCTGTTGGGCCCCTCAGCCCTCATCGTTGCGTCGACCTCCTGGAATTGGCGAATCGACTGTGCCTCCCTCGTCTCATCAATTTAATAGAAAAGCGAGTCGTAGAAGAACTCGTACGGATTTGTGCCACTAACGACAATAACGACGTTGTTGAGGTTTGCTTGAAACTTCTTGAACCATGCAAGCTTCATAATGCGGACCAACTTGCTGACTGGTGCATGAGTCATCTGTGTACCAATTACAATAAACTGTGTAAGATGTCACCAAAACTCCTGCGCACGTTACATCCAGACAACCAAGAATACCTCATGGAAAACAGATGGCCTCCTGTCTGGTATCTCAAGGATTTTGACTATTATGACAAATGCGCATCGGAGCGGGAGCGAGAAGAGCGAGTCATGTTCAAACGTGGCTCAAATGGAGGGGGTTGCCTCTGTTTTGGCTCCTCGGCCCGAGGTGCCACAGTTGAAGTGGCGCCATCTTCGTGA
Protein Sequence
MDNTEHHQELVKCVVVGDTAVGKTRLICARACNKQLSLSQLLTTHVPTVWAIDQYRIYKDVLERSWEVVDGVNVSLRLWDTFGDHEKDRRFAYGRSDVVLLCFSLASPNSLRNCKAMWYPEIRRFCPNTPVILVGCKNDLRFMYRDEAYLDFFRERSPFLRAIRKSDLVMPDQARSIARELGVTYYETSVLTYYGVNEVFENAIRAALIARRQQRFWMTNLKKVQRPLLQAPYCPPKPVARPVQVCASTFDDSLRWLLTNLPHTDVIFVVGTICIPAHRFMLAAASPSLQRLLCTDLTGELNTRSASESSMVSSFGEATSGDFNEDTEFLIRVEKPSRGGVWEQLKRRSSCQVLTSACNNSPNQRVCANRELNHPAFSSIRVQQVEDMDTQGRLTASLQTVITLSKLVTPQAMQQTLMFLYTGTIDSKFTQIQNSSLGLLMEIRQAAEFMELPELQVYVSNMQSHEEFLNPELKQRYKQAVRVRLNELCLSQGLFADVIFQLDDGCIPAHKPLLMARCDMMRAMFSGDFREGSAKVIHFPGVKCEVFRVLLCYLYCDAVGPLSPHRCVDLLELANRLCLPRLINLIEKRVVEELVRICATNDNNDVVEVCLKLLEPCKLHNADQLADWCMSHLCTNYNKLCKMSPKLLRTLHPDNQEYLMENRWPPVWYLKDFDYYDKCASEREREERVMFKRGSNGGGCLCFGSSARGATVEVAPSS

Similar Transcription Factors

Sequence clustering based on sequence similarity using MMseqs2

100% Identity
iTF_00930474; iTF_01365612; iTF_00145727; iTF_01500479; iTF_01095911; iTF_01301706; iTF_01479518; iTF_00743888; iTF_01108562; iTF_00339985; iTF_00373241;
90% Identity
iTF_01365612;
80% Identity
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