Basic Information

Gene Symbol
-
Assembly
GCA_901521435.1
Location
CABEGB010000618.1:299007-307656[-]

Transcription Factor Domain

TF Family
zf-C2H2
Domain
zf-C2H2 domain
PFAM
PF00096
TF Group
Zinc-Coordinating Group
Description
The C2H2 zinc finger is the classical zinc finger domain. The two conserved cysteines and histidines co-ordinate a zinc ion. The following pattern describes the zinc finger. #-X-C-X(1-5)-C-X3-#-X5-#-X2-H-X(3-6)-[H/C] Where X can be any amino acid, and numbers in brackets indicate the number of residues. The positions marked # are those that are important for the stable fold of the zinc finger. The final position can be either his or cys. The C2H2 zinc finger is composed of two short beta strands followed by an alpha helix. The amino terminal part of the helix binds the major groove in DNA binding zinc fingers. The accepted consensus binding sequence for Sp1 is usually defined by the asymmetric hexanucleotide core GGGCGG but this sequence does not include, among others, the GAG (=CTC) repeat that constitutes a high-affinity site for Sp1 binding to the wt1 promoter [1].
Hmmscan Out
# of c-Evalue i-Evalue score bias hmm coord from hmm coord to ali coord from ali coord to env coord from env coord to acc
1 32 1.1e-05 0.0021 19.3 1.0 1 23 208 230 208 230 0.98
2 32 0.007 1.3 10.5 3.7 1 23 251 274 251 274 0.96
3 32 0.00047 0.089 14.2 0.5 2 23 281 303 280 303 0.96
4 32 0.0022 0.42 12.0 0.1 1 21 323 343 323 344 0.95
5 32 0.0051 0.96 10.9 0.2 2 23 440 461 439 461 0.95
6 32 0.00071 0.13 13.6 0.5 1 23 466 489 466 489 0.97
7 32 0.00015 0.027 15.8 0.2 1 23 562 585 562 585 0.96
8 32 0.079 15 7.2 2.8 1 23 591 614 591 614 0.92
9 32 0.34 65 5.2 1.6 1 23 627 649 627 649 0.97
10 32 1.1e-05 0.0021 19.3 1.8 1 23 692 715 692 715 0.96
11 32 2.3 4.3e+02 2.6 0.4 1 23 748 771 748 771 0.92
12 32 0.075 14 7.2 0.7 2 23 778 801 777 801 0.94
13 32 0.7 1.3e+02 4.2 0.0 2 23 810 832 810 832 0.90
14 32 0.02 3.8 9.0 0.0 2 23 839 861 838 861 0.93
15 32 6.9e-05 0.013 16.8 3.2 1 23 869 891 869 891 0.97
16 32 0.02 3.8 9.0 1.3 2 23 928 951 927 951 0.94
17 32 0.00019 0.036 15.4 1.6 1 23 954 977 954 977 0.97
18 32 0.00053 0.1 14.0 0.1 2 23 984 1006 983 1006 0.96
19 32 0.00071 0.13 13.6 3.9 1 21 1033 1053 1033 1054 0.95
20 32 0.0021 0.39 12.1 1.8 2 23 1068 1089 1067 1090 0.93
21 32 0.28 52 5.4 1.1 1 23 1093 1116 1093 1116 0.94
22 32 0.02 3.9 9.0 2.1 2 23 1123 1146 1122 1146 0.90
23 32 2.4 4.5e+02 2.5 0.2 2 23 1154 1176 1154 1176 0.94
24 32 2.5 4.8e+02 2.4 0.0 2 23 1183 1205 1182 1205 0.88
25 32 0.18 33 6.1 2.7 2 23 1214 1236 1214 1236 0.96
26 32 0.54 1e+02 4.5 0.5 2 23 1242 1264 1241 1264 0.91
27 32 0.013 2.4 9.6 0.1 1 23 1326 1349 1326 1349 0.95
28 32 0.00014 0.026 15.9 1.1 1 21 1376 1396 1376 1397 0.95
29 32 0.25 47 5.6 1.9 2 23 1497 1519 1496 1519 0.94
30 32 0.71 1.3e+02 4.2 0.4 2 23 1526 1548 1525 1548 0.94
31 32 0.54 1e+02 4.5 2.5 1 23 1559 1581 1559 1581 0.97
32 32 0.02 3.7 9.1 0.3 1 19 1586 1604 1586 1607 0.95

Sequence Information

Coding Sequence
ATGCACATATTCGGCCAGGAAGGCCAGAATCGTCAGCTCGTCGACAAGATCCAGACGTGCTTGCCGTTCAAGATAATGGAAGACGATTGTTTGCCTAAAGTCCTGTGTTACCGATGTATGTACaacttggaaaatttttatgactttAGGACTGCGTGTGTTAACGCAGCTGCTTGGTTGGAAAGAAACAGGCCAAAGGAAGGCGCGAACGATGACGGCGCAAATGACAGCGCACAATCTGGCGAAGTGCACGCGGAACTTCTTAAGGGAAAGGATAATATGCCAGTACTTATTCCAGAGGCACCCGTAGTCAATCCCAATGCGGCATTAGGTACACCACCGAGATTAAATTCGGATGGTGAAGCAGATCCAGAAATCGAAGAGATTCTCGACACAAGTGAAGGTACGGATGAAGcTACAATAATCGACGATTCGGAAGATCGGCGATCGGAATATGAGATGGCATACGAGATGGACATGGAGACGAATCCCAGCGACTTTTTAGAAATGACCCCTATGGTTACCGAGGAAAATGAAGAGGAATGCAGTACGAATGTCGCCAGTGTCGCGACTACTCAAGATACCACGGTCTTTCCACATACGTCGCAACAACATGAAGTCTATGTCTGTTCTCTTTGCAATAAAGCGTTTAGTTCCAAGGGTCACTTATCTTTGCACGCGAAAATTCACGGTGAGAGTGTGGTCGGTGAAAGAGTAATCACCGATGATCATACTTCGTACCAACGACCTTATCAATGTGATCTTTGTCATAAATCGTATTCTACTGCGAAACATCGCTGGGGACACGTTTCTACGACACATCGGGGTCATCCTGCGGTAACGTGTGCATACTGTTCTCGCATATACTCGACACGATATAATCTTGATGAGCATATAAAATCGCGACACGCTGGTCTACCGCCACCTCCAGAATTATCGGTTCCCCATTCGCGCACGGAAACTCGTTATCAGTGCCAAACATGTCCAATGGTGTACACGGATCTAGCAGATTTCAATGCGCATCGGCAGATATGTATCCTTGAACAACGTACAGATCAAACCGAAGCGCAGAACAATAAGATTTTCGCCGATGCGTCCGATATCTCGAGTGTAGACTCGGATGACGAGAACAAAGACTTCAAGAATGCCGAGGCTAAATTAGCGAAAAATCCACAGTTAACTATATTGAAACAGGCGCTGACTAAAGGAGATAGTTTAAAACGAGAGCATTTTGATGATGATGGTTCGACATCCAGCAGCAGGCcgaaaaaaatagttaagtcagAAGAGAGCGAGACGAATCCTCAGAAGAGGTTGTATTGTGAAGCTTGTCCACAAAGTTTCACATCGATGGATAGTTTAAAAGACCACGAGATTAGGCATACCGAGAAGCCgtttatttgcaaattatGCAAGAGAGATTTTGTTTTGAGAACTTCATTAATTAAACACATTATAACGTTACATAAAGTTGATCCTACTCCTATCATTGATAATGAAAAGTGTTTGAAGGCAACGGTAATACCTCAGAATTGGAACGATCGCGTGGACGTCAGTGTTTATGAGCAAAGTGAAACGAAAGAGCCACCAGATCTCTCGTCGTCACCTGAGGTAaagataaatttagaaaatgatGATAAAGATTATAAGAACAATCACGAGAACATAGAAATCGAAACGGTATTTGTATGTGAGACTTGTAAGAGAGACTTCAATGACCGAGCATCATTATGGCTACACATACGGGCGATGCATAAAGAATACGCTGCATTTACCTGTGGAGTTTGTTTAAAGATGTGCTTTAATAATACGCAACTTCAAAATCATGTCTATTTGTATCACGGAAGGTCTAAGCTTTCAATATCGGAACAAAGAAGGTACAGTTGTACGTTATGCGGTAGACAGCATGACTCGAGAAAAAAGCTAATCAGTCATGTCTCGATACATAATATTGATCCTGTCTTTGATCCTGCGAATTTTGTACaattaaatagtaattattatattgaaaacttGAATGGTAACGAAGGAAATGAACAAGTATTAGATTTTGACGGAGAAGATGGCGAGAAGTTTAATTGTTACATTTGTTACAAATCTTTTCCGACTGAGGATCATCTTATACGACATCAGAGAAATGCTCATAAGTCTGACCAGATAATTTCATTAGGAGACGCTGCGGGTAGTGGAAATACTCTTAGTGTCAATGGTAATGGTAATAGGGCGcagtatcatttattttttgtttgtgaGGTATGTGGTAGTTCACATTCGAGCAAATGGGAACGTTGGTTGCATATCAACAATACACATAACAACGAATCTTCTATTAAGTGTGAATGGGAGAATTGCGGAAAGATATTCGCAACGAAATTGTTACGCAATGAGCATCTCCAGCATCATGCGTTACAAGGACCCTCGCCGAACACCTGCGAAATATGTGGGAAATTGTGGCCTACTCGCGTCGATTATTGGAAACACGTGATGGGCGTACACGCGGACACAGTGCCTCTAATTTGCGGTGTTTGTCTGAAAGTATTTTCCGACGTTATGCAATTAAGCGCACATGTGAAGGCGAAACATTGGCCACTAACCAGTGGTGATTTCTGTTGTGATATTTGCGGTAGACCATATTCCAATAAATCGAAGATGTCTCGACATAGAAAGATCCATGGTTTGGAGGCGGCTATGGAGGCCGCGTGTGATAATAGCAGTTTTAATGAAACGACTAATGAATCGGTCAAGCCTGATCACAACAATGGCGTTTCGGAAATAGAGTTAAGTTGCGAGCAGTGTCCTGAGCTCAGCTTCACGACGTTGGACAGTTTGTGTAATCATCGGCGGATAACACATAATCTTTTTCCATGCGATTTGTGCAACAAATTCTATGGCAGAACGTCGCACCTGTGGAAGCATGTAAATAGGGTGCATAAAGGACACGCAGATGTAACTTGTCCTTATTGCGCAAAAACAAGCGCATCAAGGGATCATCTGGCAGCACATATCGCCAAAATTCATAGGTTTATGCCCATAATAGGTAAAGATAATCAGAACTGCGTCGCTTCCAAGTCCCTAAATGTAGAAGACGGTGTCTTacattattgtgaaaaatgtaACAAGGGATTCCATAAGCGCTATTTGCTTCGCCGTCACATGAAAGGCTGTCAAAACTATCGTAAAGATCCTGGTGCATTGTTGACTCGTTGCCGGGCCTGCGAGAGGATATTCAAGGATCGTGCGAGTCTACAGAAACACATTGAGAATCATCATAGCACATATACTTGCCACTTGTGTAACGAAACGATCACTTCCAAACTAGGCATCATGACACACAACCGCGTTAATCATATGGATCATCCGGATTTGACGTGCGATCATCCAAGTTGTAAAAAACTCTTCCGCACTAAAGAAGATCTAGAATCTCATCGAAAGGACCACAAGTATCATAGCAACCCAAATGTTTGTGATTTTTGCGGTGACACCGTGGAAAATAAGCTGAAACTGAAGATGCATGTGTTATCGTTGCATCGAAATGAGATCGGCGTATCCTGTGGCGTTTGTCTCATTCCTATGAAGGACCCCAAAGATTTGAAGAAACATGTCGAAGCGGAGCACAGCAGCGTCCTTTCCAATCCAAACACGTGTCAGGTATGTGGAAAGCAATATGCATCCAAGTGGAAGGCTTTTGATCACACAAAGAAATGTCATGGCAAGGTTTTCCTCACGTGTAAACAGTGTCTGGCGGTTTTCACAGATGAAAACGATATACGCGATCATTACGAACACATACATAACGTTCCGAAGGACCAATTAGCTGTTTTTGAATATAGAATGGATATTGGTGTAAAAAGAGAGGGTTACGAGACTCCCGACATTATTGTGAAGGAGGAACCGGATGACTTAGAGTTCGACGAAGAAATGTGCGACGAGAGTTCAAACGACTCTCGTAAACGTAGAAGATCGCCAAACGATACGTACGATTGCGAGATGTGTCCCGAGATCTTTCTAAATTCGGACACTCTTGCCAAACATTATCAGAACGTCCATAACACCGATCCTGTCCGTATGTTCAAGAAATTCAAAAAGGATAACGATGGCAAGCGCAAGATGAGAAACAGAAACAACTTTGAATGCAAGAATTGCAAAAAACAGTTCTCCACTAAGACCCTATTCTGGAATCACATCAATATATGTACACGGCGTAACTCGGTAAATAGATTTGACATGCCGAATAATGTTCCGACATCAATTCTAGAATCTCATCTGAAAAACAATCAGATTCAACGAGAAGAGGCATCGTTACCGCTGGCGAACGAATCCAACTTGAACATTCCCGACTTTAACCTATTCGAGGATATTAATTTGCAATTGTCGGCCCAGAAACCCGTGCCGAATCTTATGCCATTGTCGCAAGTGAAGGCGGGTAATGGCAAATGCTCGAGGAAAGATTCGCGCAAGGTGTATGATGAATCGACCAATACCGAGTGCACGTGTGAAGTCTGTGGTAAGCAATGGCCCGCCAAGAAACATCTATGGCAACACCTGATTCGTTTCCATCGCACTGAGGCTGCCGTTACGTGTGGTGTATGCTTGAAATTGTGTAAATCTTATCAAGATTTAGCCGATCACTTGAAGGCCGAGCATGCTCCTGTTTTGTCACCGGAGGGCAACAATTTCACTTGTAAGACATGTGGTAGATATCATAACGCGAGAAGCAAATTGTTGTTGCACATGAGCATCCATATTGGACACAACTTCCGGTGTCAAAAGTGCCAGCAAGGTTTTGTGAGCGAGGAAAAACTTAATGAACATGCAACGAACTGCAATGGCAAATCAGAGTTTGAGGATCACGCGGTAGTGGACGAAGATAATGCAAAGAACGACAATGACGAGAAGGGCAGTCTAATCGCCGACGAGACATCGGTCATCGAAGAAGCGGAGGAAGCAGAGGAAGCGGATTTCGAATCGGAAGGCGAAGGAAGTAGGGATATTCACGATGAAGACAATTCAGAAAATAGCGAAGAAGACAATTCGGAAAATAGCGACGATTCAGATAGCGATAGTAATAGTAGTTCGAGCGAAGACGAAAACGAGAACGAAGAGggggaagaagaggaggaagaaggaAATGAAAACGAAAATGAGTCTGATACAAGAACCACTAGTAGAGAGAGCGGTGATAGTGTATCATGCAATTCCGAAAGTGACGACGAATCTGATCTGAATGAAACGGAAGTGAACACGACGAAAAAGCTACAATTGAGCGATAAATTCAGGATAGCTGGTGACAATATTCAAGAGAATATGCCGATGAAGAATAACGTCCAGGACCAGAAAACCGCAATGACGGATGCAGACCAAAATAAACAAAGTAATTTGAATGATCTTTTGACGCACAGTACACCTGCAAACATGGACAAATTTGAAACATTTCATCTCGAGGAATCCGCTAAAGCTGCAGCGAGCGATATAGACTTATCTGATGATAATGAAGACGATGATGATAACGAGGAAGATGATgaggaaaataatgaaaatgaggaagaagaagaagatggtGAAGAAGGTGACGAAAATGAAGATGAGGATGAAGATGAAGGTGAGGCTGAGACTGAAAGTGAGAATGACAATGAGAATGAAGGTGAAGTTGCAGCCgagggagaggaagaagaggaagaagaagaagaggaggaggaggagagaggaggagagacaggaagaggaggaggaggaagaacaggaggatga
Protein Sequence
MHIFGQEGQNRQLVDKIQTCLPFKIMEDDCLPKVLCYRCMYNLENFYDFRTACVNAAAWLERNRPKEGANDDGANDSAQSGEVHAELLKGKDNMPVLIPEAPVVNPNAALGTPPRLNSDGEADPEIEEILDTSEGTDEATIIDDSEDRRSEYEMAYEMDMETNPSDFLEMTPMVTEENEEECSTNVASVATTQDTTVFPHTSQQHEVYVCSLCNKAFSSKGHLSLHAKIHGESVVGERVITDDHTSYQRPYQCDLCHKSYSTAKHRWGHVSTTHRGHPAVTCAYCSRIYSTRYNLDEHIKSRHAGLPPPPELSVPHSRTETRYQCQTCPMVYTDLADFNAHRQICILEQRTDQTEAQNNKIFADASDISSVDSDDENKDFKNAEAKLAKNPQLTILKQALTKGDSLKREHFDDDGSTSSSRPKKIVKSEESETNPQKRLYCEACPQSFTSMDSLKDHEIRHTEKPFICKLCKRDFVLRTSLIKHIITLHKVDPTPIIDNEKCLKATVIPQNWNDRVDVSVYEQSETKEPPDLSSSPEVKINLENDDKDYKNNHENIEIETVFVCETCKRDFNDRASLWLHIRAMHKEYAAFTCGVCLKMCFNNTQLQNHVYLYHGRSKLSISEQRRYSCTLCGRQHDSRKKLISHVSIHNIDPVFDPANFVQLNSNYYIENLNGNEGNEQVLDFDGEDGEKFNCYICYKSFPTEDHLIRHQRNAHKSDQIISLGDAAGSGNTLSVNGNGNRAQYHLFFVCEVCGSSHSSKWERWLHINNTHNNESSIKCEWENCGKIFATKLLRNEHLQHHALQGPSPNTCEICGKLWPTRVDYWKHVMGVHADTVPLICGVCLKVFSDVMQLSAHVKAKHWPLTSGDFCCDICGRPYSNKSKMSRHRKIHGLEAAMEAACDNSSFNETTNESVKPDHNNGVSEIELSCEQCPELSFTTLDSLCNHRRITHNLFPCDLCNKFYGRTSHLWKHVNRVHKGHADVTCPYCAKTSASRDHLAAHIAKIHRFMPIIGKDNQNCVASKSLNVEDGVLHYCEKCNKGFHKRYLLRRHMKGCQNYRKDPGALLTRCRACERIFKDRASLQKHIENHHSTYTCHLCNETITSKLGIMTHNRVNHMDHPDLTCDHPSCKKLFRTKEDLESHRKDHKYHSNPNVCDFCGDTVENKLKLKMHVLSLHRNEIGVSCGVCLIPMKDPKDLKKHVEAEHSSVLSNPNTCQVCGKQYASKWKAFDHTKKCHGKVFLTCKQCLAVFTDENDIRDHYEHIHNVPKDQLAVFEYRMDIGVKREGYETPDIIVKEEPDDLEFDEEMCDESSNDSRKRRRSPNDTYDCEMCPEIFLNSDTLAKHYQNVHNTDPVRMFKKFKKDNDGKRKMRNRNNFECKNCKKQFSTKTLFWNHINICTRRNSVNRFDMPNNVPTSILESHLKNNQIQREEASLPLANESNLNIPDFNLFEDINLQLSAQKPVPNLMPLSQVKAGNGKCSRKDSRKVYDESTNTECTCEVCGKQWPAKKHLWQHLIRFHRTEAAVTCGVCLKLCKSYQDLADHLKAEHAPVLSPEGNNFTCKTCGRYHNARSKLLLHMSIHIGHNFRCQKCQQGFVSEEKLNEHATNCNGKSEFEDHAVVDEDNAKNDNDEKGSLIADETSVIEEAEEAEEADFESEGEGSRDIHDEDNSENSEEDNSENSDDSDSDSNSSSSEDENENEEGEEEEEEGNENENESDTRTTSRESGDSVSCNSESDDESDLNETEVNTTKKLQLSDKFRIAGDNIQENMPMKNNVQDQKTAMTDADQNKQSNLNDLLTHSTPANMDKFETFHLEESAKAAASDIDLSDDNEDDDDNEEDDEENNENEEEEEDGEEGDENEDEDEDEGEAETESENDNENEGEVAAEGEEEEEEEEEEEEERGGETGRGGGGRTGG

Similar Transcription Factors

Sequence clustering based on sequence similarity using MMseqs2

100% Identity
iTF_01355612;
90% Identity
iTF_00885330;
80% Identity
-