Basic Information

Transcription Factor Domain

TF Family: zf-GAGA
Domain: zf-GAGA domain
PFAM: PF09237
TF Group: Zinc-Coordinating Group
Description: Members of this family bind to a 5'-GAGAG-3' DNA consensus binding site, and contain a Cys2-His2 zinc finger core as well as an N-terminal extension containing two highly basic regions. The zinc finger core binds in the DNA major groove and recognises the first three GAG bases of the consensus in a manner similar to that seen in other classical zinc finger-DNA complexes. The second basic region forms a helix that interacts in the major groove recognising the last G of the consensus, while the first basic region wraps around the DNA in the minor groove and recognises the A in the fourth position of the consensus sequence [1].
Hmmscan Out: # of c-Evalue i-Evalue score bias hmm coord from hmm coord to ali coord from ali coord to env coord from env coord to acc

1 5 2.9 1.1e+04 -3.0 0.1 26 32 171 177 169 190 0.73

2 5 0.58 2.2e+03 -0.8 0.1 26 47 224 245 213 250 0.77

3 5 0.00056 2.1 8.8 0.1 21 44 247 270 240 274 0.89

4 5 0.001 4 8.0 0.2 22 44 276 298 270 302 0.87

5 5 3.1e-06 0.012 16.1 0.2 21 46 303 328 300 334 0.90

#	of	c-Evalue	i-Evalue	score	bias	hmm coord from	hmm coord to	ali coord from	ali coord to	env coord from	env coord to	acc
1	5	2.9	1.1e+04	-3.0	0.1	26	32	171	177	169	190	0.73
2	5	0.58	2.2e+03	-0.8	0.1	26	47	224	245	213	250	0.77
3	5	0.00056	2.1	8.8	0.1	21	44	247	270	240	274	0.89
4	5	0.001	4	8.0	0.2	22	44	276	298	270	302	0.87
5	5	3.1e-06	0.012	16.1	0.2	21	46	303	328	300	334	0.90

Coding Sequence: ATGAACATGGAAGTTTTGCCATTTGAAACAGTGGTCATAAAAATTGAAAAAAATGATGAGGAATGGCGAATAAATGAAGTTCTGGAAAATCCTTTAGATATTGGAAAATTAGAAGATGAGCCTGAAGAAAATTCAGTGACTTTAAAAGATACTATTGATGTACCTGATGTCGAAGTTATTGACAGTGTAAATTTTACGTTTGGAGGATCAGCATCAGTTTTAAATGTTCAAAAAATTGACGACGAGTTAAAAGGAAATCGAGATTATCCAATAGATATTGAAGAAATCAAGATCGAAGAAAATGAAGATCCAATTTATCCAAATATTACTGATGTATCAAAGGCAAAAATCAGAAAAATTGCAGCAAAAGATCTCCAGGAAATTCCTACTGAAGAAGCTCCAAAAAATGAATCCATGTGGAAAACATTCAAGTGTGATAAATGCGCAATGGAATTTGTCAACGAAAGTTCTCTGGCGACTCACGCGAAGAAATACAAATTCAACTGCGACGTCTGTCCAAAGTGTTTCATATCAAGACAAGGATTATGGTACCACCTGAAATCGCATTACGGTCCCAAACCATTTAAATGCGAAGTATGTCCGGCTGACTTTGAATTAAAATCCGGGTTGATAGAGCACTCAAGGACTCACGCAGGAGACATGAGCTTCGCTTGTACCCTTTGTGCCTACAAAACTCGGTACAAAAGTTCCTTGAACAGACACGCTCGTGTTCATACCAGAGAGAAGCCCTTTGCTTGTGACCTCTGTTCCGCGACCTTCCGGGAACAAGGTCACTTAAAGCGACACAGTCGGATTCATACTGGAGAGAAGCGCTACACCTGTGATGTCTGTTCTGCAAAGTTCAGGGAAAAAAGCACCTTAAGGCAGCATATTATTATTCACACTGGGGAAAAACCTTACACTTGTCCTGTTTGTGCGATTAATTTTAGGCAGCAGACTCATTTGGATAGACATATGGTCATGCACAATGGAGAAAAAAGTTTTGCTTGTCAATTTTGTCCCTTGGAGTTTCATAGATTGAGTAGTTTTGCTAACCACGTGCTCACTCACAATCTCGAAAAAAAATAA
Protein Sequence: MNMEVLPFETVVIKIEKNDEEWRINEVLENPLDIGKLEDEPEENSVTLKDTIDVPDVEVIDSVNFTFGGSASVLNVQKIDDELKGNRDYPIDIEEIKIEENEDPIYPNITDVSKAKIRKIAAKDLQEIPTEEAPKNESMWKTFKCDKCAMEFVNESSLATHAKKYKFNCDVCPKCFISRQGLWYHLKSHYGPKPFKCEVCPADFELKSGLIEHSRTHAGDMSFACTLCAYKTRYKSSLNRHARVHTREKPFACDLCSATFREQGHLKRHSRIHTGEKRYTCDVCSAKFREKSTLRQHIIIHTGEKPYTCPVCAINFRQQTHLDRHMVMHNGEKSFACQFCPLEFHRLSSFANHVLTHNLEKK

Sequence clustering based on sequence similarity using MMseqs2