Basic Information

Transcription Factor Domain

TF Family: PC4
Domain: PC4 domain
PFAM: PF02229
TF Group: Unclassified Structure
Description: This domain is found at the C-terminal end of Activated RNA polymerase II transcriptional coactivator p15 from humans, YdbC from Lactococcus lactis, and other PC4 family members. p15 has a bipartite structure composed of an N-terminal regulatory domain and a carboxy-terminal cryptic DNA-binding domain [1-4]. Activity is controlled by protein kinases that target the regulatory domain.
Hmmscan Out: # of c-Evalue i-Evalue score bias hmm coord from hmm coord to ali coord from ali coord to env coord from env coord to acc

1 3 0.62 8.7e+03 -4.0 0.9 31 37 24 30 21 30 0.77

2 3 0.45 6.3e+03 -3.6 1.6 28 37 40 50 38 50 0.75

3 3 1.5e-26 2.1e-22 78.0 0.2 1 51 63 115 63 116 0.97

#	of	c-Evalue	i-Evalue	score	bias	hmm coord from	hmm coord to	ali coord from	ali coord to	env coord from	env coord to	acc
1	3	0.62	8.7e+03	-4.0	0.9	31	37	24	30	21	30	0.77
2	3	0.45	6.3e+03	-3.6	1.6	28	37	40	50	38	50	0.75
3	3	1.5e-26	2.1e-22	78.0	0.2	1	51	63	115	63	116	0.97

Coding Sequence: ATGCCGAAAAAATCAAGAGAGTATGTTTCAAGCGACGAAAGTGAATCTGGTAGTAATTCCGAGTTGAAAGAAGAAAAACCAAAAAAGAAGCCAAAGCGCGACGAAAAAAAGTCTAAAAAGGAAGAGAAAGAGGACAAGCCTGCTAAAAAAGCGTCTTCCAGCAAGGCCGACGAGGAGGAGCCAACCTGGAGCATTGGTAACAAGAGACAGGTCACTGTTCGTACATTTAAGGGAAAATTGTACATTGACATTCGTGAGATGTATTTAGATCCCAACAGTGGTGATCTGAAGCCTGGTCGCAAAGGAATTTCTTTGACTCCTGAGAACTACAACAAGCTAAAAGATGTATTAGCAGAGGTTGATGAAGCAGTTGCTCGCAAGGCATAA
Protein Sequence: MPKKSREYVSSDESESGSNSELKEEKPKKKPKRDEKKSKKEEKEDKPAKKASSSKADEEEPTWSIGNKRQVTVRTFKGKLYIDIREMYLDPNSGDLKPGRKGISLTPENYNKLKDVLAEVDEAVARKA

Sequence clustering based on sequence similarity using MMseqs2