Basic Information

Gene Symbol
zfy1
Assembly
GCA_963675405.1
Location
OY776253.1:10025980-10036217[-]

Transcription Factor Domain

TF Family
zf-C2H2
Domain
zf-C2H2 domain
PFAM
PF00096
TF Group
Zinc-Coordinating Group
Description
The C2H2 zinc finger is the classical zinc finger domain. The two conserved cysteines and histidines co-ordinate a zinc ion. The following pattern describes the zinc finger. #-X-C-X(1-5)-C-X3-#-X5-#-X2-H-X(3-6)-[H/C] Where X can be any amino acid, and numbers in brackets indicate the number of residues. The positions marked # are those that are important for the stable fold of the zinc finger. The final position can be either his or cys. The C2H2 zinc finger is composed of two short beta strands followed by an alpha helix. The amino terminal part of the helix binds the major groove in DNA binding zinc fingers. The accepted consensus binding sequence for Sp1 is usually defined by the asymmetric hexanucleotide core GGGCGG but this sequence does not include, among others, the GAG (=CTC) repeat that constitutes a high-affinity site for Sp1 binding to the wt1 promoter [1].
Hmmscan Out
# of c-Evalue i-Evalue score bias hmm coord from hmm coord to ali coord from ali coord to env coord from env coord to acc
1 13 1.9 1.3e+02 4.0 0.3 2 23 6 27 5 27 0.96
2 13 3.5 2.5e+02 3.2 0.0 1 23 1137 1159 1137 1159 0.94
3 13 2.4e-05 0.0016 19.4 0.8 2 23 1162 1183 1161 1183 0.96
4 13 0.00053 0.037 15.2 2.0 1 23 1189 1211 1189 1211 0.98
5 13 0.014 0.94 10.8 4.9 1 23 1217 1239 1217 1240 0.96
6 13 1.8 1.2e+02 4.1 0.4 5 23 1253 1271 1252 1271 0.96
7 13 0.018 1.3 10.4 0.7 3 23 1278 1299 1277 1299 0.96
8 13 0.0011 0.074 14.2 0.2 2 23 1317 1337 1316 1337 0.97
9 13 5e-05 0.0035 18.4 0.5 1 20 1343 1362 1343 1365 0.92
10 13 0.0095 0.66 11.3 2.1 1 23 1373 1395 1373 1395 0.99
11 13 0.0071 0.49 11.6 7.2 1 23 1401 1423 1401 1423 0.98
12 13 9.8e-06 0.00068 20.6 1.1 1 23 1429 1453 1429 1453 0.97
13 13 0.00064 0.044 14.9 5.5 1 23 1459 1481 1459 1482 0.96

Sequence Information

Coding Sequence
ATGGACCAGCTCGTGCAGTGCCCCGTCTGCACACTCTTCCTGCACAATGGAATGAGCCTGGAGTCTCATCTCGACACACATCCCAAAGACCAAGTGATCAAAGCGCTCTGCAGCATCACCAAAACAAACACCAGCTGTGTCAGTAGCCGAACACCCACCCCTGCCAATTCTGAGAGATCTTATAGGAGCGGGTCCAGAACACCCATCACCGAAGACAGTGGAACTAATTCTTGGAATGGAGCCAAGGATCATGAACGCTACTGGGCTAGGACACCTAGTGGCTCCAGCCGGACCCCTAGTGGGACCTCCAGTCGTGGGCTCAGCCGAACACCCAGCAGGACCCCTAGTAGAACCCCCAGCAGGACCCCTAGTAGAACCCCTAGTAGAACAGCCAGATCTCAATCATCAGCTAACATTTCAAGAAACTGCACTCCTGATAttagattggttgataatttaGCGTTTGAAACTACAACACTTAGTAGTTCATCACAATCTCGTCATTCTATGTCACCTTCTGTGCTGAAATCTGACAAACCTCCACGAACGTACCCACCGGCCATTATACCAGATTATGATCAGCAGTTCATGGACTACTCGGACCAGCAAGATGACAGGGAAGTGAAGTATTCTCGGACTGCTGAATATAATGCCCTCGACGTCAACAATATGTATTCTTACAATGTGCCAATGATCGGAACCAGTGGCAAAATGCAATCATTACCGCCTCATGTGTCCCGGAAGAGACATGAATCAGTCAAGGTCAGCAGTGCTATGAAGTCAAACAACTTACTCAACCTTGTTAAGAACAACGTTGGTGGAATGCAGTGTTTACCTCCTTACGTGGCCAACCGTAGTGCTCCCTATCAGATAATGCCCAATGCTCCTACATTTGTTCAGAAAAATATGCAGAATAGTATGGTAATGACAAGTGGATTACCCAACACCCAAGTTCAAATTGAAACCAAAAGTGGACTTCCGTTAGTTCCGAACCATTTTAATCTGAGCTCTGGTTTCACCCCCGGAACAACTGTTGTTACTCAGAACTCTCAATACATCTATCAAGAAATGGTGCAAAATATTGATCCAAAGTCCTTTGTACCTACAATGCCTCCAGTATTCACGGGTCATGAGAATATAACAGCTAATGTTGCCCAAGCAAGTTCAGAATGTACAAGGATGTATCAGAATGTGATGCTAGTTGATCAGTTTGGGAATACTTCCTGTATGTATACTCCGCAGACAATACTGCCCAAAGCAACGTGTGCTCCTCCGCTGTTCACGGAGAGTACTTCTAGGTCGGTTAATACATTTGTCCAAAAACCAGGACCGGTAAAGAAAGATTCAAATATGTTCACAGAGAGTACATCTAAGTCAGTGAATACATTTGTGCATAAACCAGGACCAGCAAAAAAAGATTCAAGCAAGACACTAATCATAGAAATAGGACCCATAATGCCGTCACAGAGATCTACAAGCAAAATCTCTAACAGAGCATCTACGAGCACTGCGACACTACAGACGAGAGGTTTGATCCCCAATGTACCTGTAATACATCCACCTATACCGGAGGCTCCCAGTATTTCAATAACAGAAAAGATTGAGAAAACTGAAATCCCGTGCACTAGTAGGGGGTTAAAGATTCTGAGCAATATCAAGGTTGAAGTTCCAGTGCAACACATCAAAAGCATGATAAACACCGTGATGGATCTGACCGGTCCTGACGACGCTGTGTACCCGGAATGCAGGAGTCCCGAAAAGATCTTGCCGGATTTAAACGTTGGTAAAGAAAGGGTCGATGACTTCGCGCAGCCGCCGACACCCGGCGACGACAGTTCCCATTCGTTCGAACTGAAAAAGTTCGCAAGTGCTACCTCAATCAAAGACTTTAATAGTAAAACTAATAGCGTAGATAATAAACTAGAAAGTGATTTCGGCGATAGCTGTCCGGTACCGGATCTGATTTGTAACGAAAAGCCCTCTATCTCGCCCTGCAGCGAGCTCTCGGAGAGCGGAGAGAACTCTGTCGATCGCACCGTGTCCCCCAAGCCGCACTCCAGTGGAGTTATCGTAAGGAAGGAGAGCGACGTAGATTATAAAAGGAAAGCGCCGATGAAGATAAGACTGAACAACATTTTTGTCAAAAAGAGCAAAAAGATTCTGCAAATAAAGAATGTTAAAATGGCCGCGAGTCGAGAGAATACTCCAGTCGCGTGCTCGTCGAAAACAGTAGCGCCTGAGAATTTCGCAGCAGCGAAGGTAGCTCAATCTCCGAAGCGCACCGAAAAGACACGCACGACCATTTCAATCGAGGAGATCAAAGAGAAAAAAGAAGATGTGAATCCCGTGGAAGAAGTGAAGATGCCGCCGGCGCCTGCTAAGTCCGAGAGCGTTCCCGTGAAAGAAGAGTTCAGTTCTAGTAACGATTGCGCGTTCAGTAACGAGGCCCCCGGTCCGGCGCGGGACCTGGGCCCTCTGGACCCACTGCGCCCCACCACAGTCAGCTATGCAAACATGTCCCCTTCAGACTTCGACGACGAATCCAGCAACCGCGAGCTCTTAGACCTCGAAGGCGGGAAGAACAAGCAATTCGTCAGCATGATGAACGATAACTACTTCGGTGACAACATCTACGCGGATTACTTCACCCCGGACCGAGTTGAAGCGTTCGACGACAAAGGACCTACAGTTTTCAAAGATAATTCGAAAGAAGCGTTTTCATGCAACATTTGGGGAGAGCCGTCTTCTAAAGAGAACGAATTCGTCCTCCCCAATTTCATTCACGAGAGTTACAAGATTGCGGATAGTGGGGTAGAGTATGCCGATAGTGAGGATGCGAGAGATGACAACAAAGCGGATGTGCCGCCGTTGAATATTTGCGCCGATGAGCGGATGCCGCCGAGGGGCGAGATCAGCGGACAGGAGAGCAACGGAGACATGGAATCGTCATGGAATGGGATGTACCCAGAGGTGACTCCAGCGGAGCCCTACGACCTTATGGCGCGCGAGAGTTGGGTGTCCGACGGATCAGAACTTGATGTCACCGAGAAGAGAGACACCCTAGAGGAAGAGCTACTATTCCCAAAAGTGCGAATGTACGCCTGCATTACTTGCGGCTCCAAACACAACTCGCTCAAAGAGCTGCGCGCGCACAAGGCAGCCGAGCATGCCACGCCCACCAGCTCCAAGACTACCTACAGCAGACTGCTCACGGCACGCACCATCAAAAAGGAGGAGAAAGCTGACGGCTTGTCCTGCGCAGCCAACCTGCTCACAATAGACTCGAAAGAAAGTATATCTACATCTATACTACAAGTGTTCGATCCCGACGCGATAGAAGAAACTAAGCCAAAAGTCGGCAGTCTGCGCAGCCTGCTCAACAAGGAGCCCAAACGGAAACGGCGGGACTTCGTCTGTCCCACTTGTAAAGTGGACCAGGTGACGGAGCCAGCATTTACAGCTCATCTCAAAATCCACCCCCTGGAGTGTCTCACGTGCGGGAAGTTCTTCTACCGGCGCGCTAACCTTCAGCTCCACGTGAAGACGCATCTCGGCATCAAGGATTATAAATGTGACATTTGCGAGAAGCGCTTCGTGACGCGGCAGAAGCTTGGCGAGCACCACAACATCCACACGGGTCGCACTCCATACAAGTGCACCTTCTGCGACGACACCTTCCGCAGATACTCCAACATGGTGCAGCATCGGGACCGGCACCACCTGCACAAGCGCGTGAAGAGCCGCGACTTCGTGTGCCAGTGCGGCGCCGTGTTCCAGTCGCGCGCCAAGTTCCTGTGGCACAAGGAGACGCACGCCGAGCGGCCGCGCGCCTGCCTCTACTGCAGCGACAAGTTCGTGCACGCCGCCTCGCTCACGCGCCACGTGCGCCGCGCGCACAACGCGCTGTACCTGGCGCAGCACGCGGCCGGTCGCGCCGGCGAGAACGTCACCTGCCCCATCTGCAAGCAGGTGTACTTGCGCAGTAACCTGCGCGCGCATCTCCAAACGCACAGCGGCAAGCGTCCCTACGTGTGCGTGATCTGCAACAAGGCCTTCACCACCAAGTGGAACCTCAAACTACACCGCTGGACGCACATGTCACGGTCCGCCAAGCCTTTCAAATGCTCACTCTGCAAAGGAGCGTTCATCCGTCACACGGAGTACGTCTCACACATGAACTCGCACAAGTCCGTCCGCCCTTACACCTGCAACTACTGCGGCTGTCAGTTTATAAGGAAGTACAACTGTCAGCGGCACGTCAGAGAGCACGAAATGGCGAAGAAGTTCGTATGCAACGTCCCGGAGTGCGGCAAGTCTTTCCACCGGAGCTATTACCTCTCCGAGCATATGAAGGTGCATAGCGGCGTGAGGCCATTCTCCTGTGATATATGCGACAAAACATCCAGCAATAAATCTAATCATAATAAGCATATGAAAATTCACCATGCTAGGGAAATGGTCGCGTCAGAAGCCTAG
Protein Sequence
MDQLVQCPVCTLFLHNGMSLESHLDTHPKDQVIKALCSITKTNTSCVSSRTPTPANSERSYRSGSRTPITEDSGTNSWNGAKDHERYWARTPSGSSRTPSGTSSRGLSRTPSRTPSRTPSRTPSRTPSRTARSQSSANISRNCTPDIRLVDNLAFETTTLSSSSQSRHSMSPSVLKSDKPPRTYPPAIIPDYDQQFMDYSDQQDDREVKYSRTAEYNALDVNNMYSYNVPMIGTSGKMQSLPPHVSRKRHESVKVSSAMKSNNLLNLVKNNVGGMQCLPPYVANRSAPYQIMPNAPTFVQKNMQNSMVMTSGLPNTQVQIETKSGLPLVPNHFNLSSGFTPGTTVVTQNSQYIYQEMVQNIDPKSFVPTMPPVFTGHENITANVAQASSECTRMYQNVMLVDQFGNTSCMYTPQTILPKATCAPPLFTESTSRSVNTFVQKPGPVKKDSNMFTESTSKSVNTFVHKPGPAKKDSSKTLIIEIGPIMPSQRSTSKISNRASTSTATLQTRGLIPNVPVIHPPIPEAPSISITEKIEKTEIPCTSRGLKILSNIKVEVPVQHIKSMINTVMDLTGPDDAVYPECRSPEKILPDLNVGKERVDDFAQPPTPGDDSSHSFELKKFASATSIKDFNSKTNSVDNKLESDFGDSCPVPDLICNEKPSISPCSELSESGENSVDRTVSPKPHSSGVIVRKESDVDYKRKAPMKIRLNNIFVKKSKKILQIKNVKMAASRENTPVACSSKTVAPENFAAAKVAQSPKRTEKTRTTISIEEIKEKKEDVNPVEEVKMPPAPAKSESVPVKEEFSSSNDCAFSNEAPGPARDLGPLDPLRPTTVSYANMSPSDFDDESSNRELLDLEGGKNKQFVSMMNDNYFGDNIYADYFTPDRVEAFDDKGPTVFKDNSKEAFSCNIWGEPSSKENEFVLPNFIHESYKIADSGVEYADSEDARDDNKADVPPLNICADERMPPRGEISGQESNGDMESSWNGMYPEVTPAEPYDLMARESWVSDGSELDVTEKRDTLEEELLFPKVRMYACITCGSKHNSLKELRAHKAAEHATPTSSKTTYSRLLTARTIKKEEKADGLSCAANLLTIDSKESISTSILQVFDPDAIEETKPKVGSLRSLLNKEPKRKRRDFVCPTCKVDQVTEPAFTAHLKIHPLECLTCGKFFYRRANLQLHVKTHLGIKDYKCDICEKRFVTRQKLGEHHNIHTGRTPYKCTFCDDTFRRYSNMVQHRDRHHLHKRVKSRDFVCQCGAVFQSRAKFLWHKETHAERPRACLYCSDKFVHAASLTRHVRRAHNALYLAQHAAGRAGENVTCPICKQVYLRSNLRAHLQTHSGKRPYVCVICNKAFTTKWNLKLHRWTHMSRSAKPFKCSLCKGAFIRHTEYVSHMNSHKSVRPYTCNYCGCQFIRKYNCQRHVREHEMAKKFVCNVPECGKSFHRSYYLSEHMKVHSGVRPFSCDICDKTSSNKSNHNKHMKIHHAREMVASEA

Similar Transcription Factors

Sequence clustering based on sequence similarity using MMseqs2

100% Identity
iTF_00267528;
90% Identity
-
80% Identity
-