Basic Information

Transcription Factor Domain

TF Family: zf-GAGA
Domain: zf-GAGA domain
PFAM: PF09237
TF Group: Zinc-Coordinating Group
Description: Members of this family bind to a 5'-GAGAG-3' DNA consensus binding site, and contain a Cys2-His2 zinc finger core as well as an N-terminal extension containing two highly basic regions. The zinc finger core binds in the DNA major groove and recognises the first three GAG bases of the consensus in a manner similar to that seen in other classical zinc finger-DNA complexes. The second basic region forms a helix that interacts in the major groove recognising the last G of the consensus, while the first basic region wraps around the DNA in the minor groove and recognises the A in the fourth position of the consensus sequence [1].
Hmmscan Out: # of c-Evalue i-Evalue score bias hmm coord from hmm coord to ali coord from ali coord to env coord from env coord to acc

1 12 0.53 9.4e+03 -1.7 0.0 30 36 3 9 2 15 0.83

2 12 0.0046 81 5.0 0.2 25 36 19 30 12 35 0.87

3 12 0.0051 89 4.8 0.2 25 36 40 51 35 55 0.87

4 12 0.0047 82 4.9 0.2 25 36 61 72 54 76 0.87

5 12 0.0049 87 4.9 0.2 25 36 82 93 77 99 0.88

6 12 0.0045 79 5.0 0.1 25 36 103 114 95 118 0.87

7 12 0.0045 79 5.0 0.1 25 36 124 135 116 139 0.87

8 12 0.0044 77 5.0 0.2 25 36 145 156 137 162 0.87

9 12 0.0045 79 5.0 0.1 25 36 166 177 158 181 0.87

10 12 0.0047 82 4.9 0.2 25 36 187 198 180 203 0.87

11 12 0.0046 81 5.0 0.2 25 36 208 219 201 224 0.87

12 12 0.0061 1.1e+02 4.6 1.8 39 39 243 243 222 266 0.60

#	of	c-Evalue	i-Evalue	score	bias	hmm coord from	hmm coord to	ali coord from	ali coord to	env coord from	env coord to	acc
1	12	0.53	9.4e+03	-1.7	0.0	30	36	3	9	2	15	0.83
2	12	0.0046	81	5.0	0.2	25	36	19	30	12	35	0.87
3	12	0.0051	89	4.8	0.2	25	36	40	51	35	55	0.87
4	12	0.0047	82	4.9	0.2	25	36	61	72	54	76	0.87
5	12	0.0049	87	4.9	0.2	25	36	82	93	77	99	0.88
6	12	0.0045	79	5.0	0.1	25	36	103	114	95	118	0.87
7	12	0.0045	79	5.0	0.1	25	36	124	135	116	139	0.87
8	12	0.0044	77	5.0	0.2	25	36	145	156	137	162	0.87
9	12	0.0045	79	5.0	0.1	25	36	166	177	158	181	0.87
10	12	0.0047	82	4.9	0.2	25	36	187	198	180	203	0.87
11	12	0.0046	81	5.0	0.2	25	36	208	219	201	224	0.87
12	12	0.0061	1.1e+02	4.6	1.8	39	39	243	243	222	266	0.60

Coding Sequence: ATGGTTCTTTATGCAGTGATAAGGAATGTTGAAAGTGCCCCTGCATGCAGCAGGAACACGTGCATGGTTCTTTATGCAGTGATAAGGAATGTTGAAAGTGCCCCTGCATGCAGCAGGAACACGTGCATGGTTCTTTATGCAGTGATAAGGAATGTTGAAAGTGCCCCTGCATGCAGCAGGAACACGTGCATGGTTCTTTATGCAGTGATAAGGAATGTTGAAAGTGCCCCTGCATGCAGCAGGAACACGTGCATGGTTCTTTATGCAGTGATAAGGAATGTTGAAAGTGCCCCTGCATGCAGCAGGAACACGTGCATGGTTCTTTATGCAGTGATAAGGAATGTTGAAAGTGCCCCTGCATGCAGCAGGAACACGTGCATGGTTCTTTATGCAGTGATAAGGAATGTTGAAAGTGCCCCTGCATGCAGCAGGAACACGTGCATGGTTCTTTATGCAGTGATAAGGAATGTTGAAAGTGCCCCTGCATGCAGCAGGAACACGTGCATGGTTCTTTATGCAGTGATAAGGAATGTTGAAAGTGCCCCTGCATGCAGCAGGAACACGTGCATGGTTCTTTATGCAGTGATAAGGAATGTTGAAAGTGCCCCTGCATGCAGCAGGAACACGTGCATGGTTCTTTATGCAGTGATAAGGAATGTTGAAAGTGCCCCTGCATGCAGCAGGAACACGTGCATGGTTCTTTATGCAGTGATAAGGAATGTTGAAAGTGCCCCTGCATGCAGCAGGAACACGTGCATGGTTCTTTATGCAGTGATAAGGAATGTTGAAAGTGCCCCTGCATGCAGCAGGAACACGTGCATGGTTCTTCTGTTTGCAGAATCTGTAATGGTTAGGAGGTGTGAAGATCTTGTTGTGCAAGGATATAAAAGAGTAGGATGA
Protein Sequence: MVLYAVIRNVESAPACSRNTCMVLYAVIRNVESAPACSRNTCMVLYAVIRNVESAPACSRNTCMVLYAVIRNVESAPACSRNTCMVLYAVIRNVESAPACSRNTCMVLYAVIRNVESAPACSRNTCMVLYAVIRNVESAPACSRNTCMVLYAVIRNVESAPACSRNTCMVLYAVIRNVESAPACSRNTCMVLYAVIRNVESAPACSRNTCMVLYAVIRNVESAPACSRNTCMVLYAVIRNVESAPACSRNTCMVLYAVIRNVESAPACSRNTCMVLLFAESVMVRRCEDLVVQGYKRVG*

Sequence clustering based on sequence similarity using MMseqs2