Basic Information

Gene Symbol
-
Assembly
GCA_013340265.1
Location
BLKM01000432.1:1012552-1021897[-]

Transcription Factor Domain

TF Family
zf-C2H2
Domain
zf-C2H2 domain
PFAM
PF00096
TF Group
Zinc-Coordinating Group
Description
The C2H2 zinc finger is the classical zinc finger domain. The two conserved cysteines and histidines co-ordinate a zinc ion. The following pattern describes the zinc finger. #-X-C-X(1-5)-C-X3-#-X5-#-X2-H-X(3-6)-[H/C] Where X can be any amino acid, and numbers in brackets indicate the number of residues. The positions marked # are those that are important for the stable fold of the zinc finger. The final position can be either his or cys. The C2H2 zinc finger is composed of two short beta strands followed by an alpha helix. The amino terminal part of the helix binds the major groove in DNA binding zinc fingers. The accepted consensus binding sequence for Sp1 is usually defined by the asymmetric hexanucleotide core GGGCGG but this sequence does not include, among others, the GAG (=CTC) repeat that constitutes a high-affinity site for Sp1 binding to the wt1 promoter [1].
Hmmscan Out
# of c-Evalue i-Evalue score bias hmm coord from hmm coord to ali coord from ali coord to env coord from env coord to acc
1 22 5.7e-05 0.0028 17.5 0.7 1 23 284 306 284 306 0.96
2 22 0.0002 0.0096 15.8 1.1 1 23 312 334 312 334 0.94
3 22 2.1e-06 0.0001 22.0 3.5 1 23 339 361 339 361 0.96
4 22 1.9e-05 0.00091 19.1 2.7 3 23 369 389 367 389 0.93
5 22 3.4e-05 0.0017 18.2 0.9 2 23 396 417 395 417 0.97
6 22 7.8e-06 0.00038 20.3 3.1 1 23 423 445 423 445 0.96
7 22 4.9e-06 0.00024 20.9 0.4 3 23 453 473 452 473 0.97
8 22 4.6e-05 0.0022 17.8 1.1 3 23 481 501 479 501 0.90
9 22 0.0005 0.024 14.6 0.5 1 23 507 529 507 529 0.95
10 22 5.1e-06 0.00025 20.8 8.3 1 23 535 557 535 557 0.96
11 22 0.01 0.49 10.5 4.9 3 23 565 585 563 585 0.94
12 22 1.6e-06 7.6e-05 22.4 4.6 1 23 591 613 591 613 0.95
13 22 4.6e-06 0.00022 21.0 1.9 1 23 619 641 619 641 0.96
14 22 2.5e-05 0.0012 18.7 2.6 1 23 647 669 647 669 0.96
15 22 0.00016 0.0075 16.2 3.3 3 23 677 697 675 697 0.94
16 22 4e-06 0.00019 21.2 2.5 1 23 703 725 703 725 0.96
17 22 2.3e-06 0.00011 21.9 0.4 1 23 731 753 731 753 0.93
18 22 9e-07 4.3e-05 23.2 2.9 1 23 759 781 759 781 0.96
19 22 0.00042 0.02 14.8 5.3 1 23 787 809 787 809 0.97
20 22 6.4e-08 3.1e-06 26.8 0.9 1 23 815 837 815 837 0.98
21 22 1.4e-06 6.9e-05 22.6 0.2 1 23 843 865 843 865 0.98
22 22 4e-05 0.002 18.0 2.2 1 23 871 894 871 894 0.96

Sequence Information

Coding Sequence
atgaatgaaaccATGGTTCTGAACTTCAGCAGAATATGTCGGTTGTGCTTGAGTGATCATAAAACACTCTTGCCTCTTTTTAATACTGCAGAGAAAGTACAAGAAAAGATACATACCATTTCACCCACAATAGAGGTATATGCTGGAGATGGCCTACCAGCCCAGATATGCAAGGAATGTGTCCATCAGGTTAACATATCTTACAAATTCATACTGCAGTGTGAGAGGTCAAATGCTACTCTGCGACACCACTTGAACAACCAGCGGCCACATGACACTCCAGTTCAGGTTGTTCTGAAAGAAGAGCCCTCACTGTGTGATGACACAGAGTCAACTAATGAACTACTTCAGTCAACTGGCAATGGAAaccaagaaaatGCCCTTGGCAGTGAAACAGATGTGACTGttgatgaagatggtgattcAGACTCAAGTGATGTAAGCCTTAAAGATGGTTCTGTGAGCCCTGATGAAGATGCTGTAGAGCCAGAGAATGAAGTGAATACTGACACAtgggacaaaactgaaacatgtgaCACATCACTGGGTAGGAAGTCATCACGGGTCATGAAGGATGAAGACATCATTGCGCCATACCCACACACGAAGGGCAGGAGAAACACTCCGCCAACAGACACTTCTGTGTACCACCTGAAACATGAAGACATCAGTGTGTCAGATCAATGCATTAAGAAGACCAGCAGTGGCAGCACACCAACACCAGCCACACTGACACAAGACATGAAACATGAAGACGTCAGTGTGCCAGATTCATGTATCAGTGCTGCAAAAAGCACTCTACCATCAAGCACATCTCATTATGTGGATAATAATGGGGAAACAGAACAGTACGCATGTGATGTATGCAACAAGTCATTCAACACTGAGAAAGATATGAAAAAGCATTCTCTTGTACACCCAGAAGACAAACCATACAGTTGTTCTGAGTGTGGGAGTTCTTTTCAGTATAAATCAAGCCTAACAAATCACACAGTATTACATTCCCAAGACTCTCATATGTGTACAGAATGTGGGAAAGTATTCCATTCCAAATCAAATCTCACTCAGCACCTTGCCTCCCATTCTGAGGCCAGGCCACATCTCTGTTCTCTGTGTGGTAAATCcttcaaatataaatcaaatCTCAGCCAACATACAGCTCTACATGCTAGAGACATGCCAGTACAGtgtaatgtttgtaacaaacacTTTGGCTCCAAGACTGATCTTATGATTCACATCCTTTCTCATTTAGAGGAAATGCCACACCAGTGTTCAGAGTGTGGCAAATGCTTCAACAGTGAATCTCAACTGTCTGATCATCAGGCTCTTCATGCAGAAACAAACCAACATGGTTGCTCTGTCTGtggtaaatatttcaaaacaaaatacaatctGACTGTCCATCAAGCATTGCACACCAAGGATAGGTCACACCTTTGTACTGTATGTGGTAAGGCTTTCAAGTACAAGTCTAACCTTTTGGAGCACAGCGCCCTACACACAGAAGACAAACCTTTCCTTTGTACTCAGTGTGGTAAAGCATTCGGCGGCAAATCCAAGTACTCTAGCCACCTTGCCACACACTCAGAAGACAGACCGTATCAGTGCTCCATATGTGGCAAGTGTTTCAAGCATAAGTCAAATCTGTGCAATCATAAAGCATTACATGTGGAGAATGGGCCCCACCTGTGTAATGTATGTGGTAAATCTTTCAGCTGCAAGTCTAAGTTCACAAGCCATGTTGCGTCCCATTCTGAAGAGAGACCACACCAATGCCCTGTATGTGGGAAAAGCTTCAAATACAAGTCAAATCTATGTAATCATAAAGCATTACATGTAGAAAATGGCCCCCATATGTGTACTTTCTGCAGTAAATCCTTTGGCACCAAGTCAAATCTCATAAAACACATTGCGATTCATTCTGAGGAGAGACCATTTCAGTGTTCTGTTTGTGGTAAGGGATTTAAATACATGTCTAATCTTTGTAATCATAAAGCATTACATGTAGAGAATGGTCCTCATCTTTGCACAGTGTGTGGTAAATCTTTCAGCTGTAAATCAAATCTaatgaaacatgtggcagtgcATTCAGAAGCAAGACCATACCAGTGTCCAATATGTGGCAAGGGATTTAAATATATGTCTAATCTTTGTAatcacaaaacattacacacacagaaaagtcCCTATCTCTGTGCAGTATGTGGGAAATCATTTAGCAGCAAGTCCAATCTGATGACCCATTCTGCATCTCATTCTGACGACAGGCGCCATCAGTGTTCCATATGTGGAAAGTCGTTCAAATTCAAGTCCAGTCTTACTTCACACCAAGCTCTGCATTCACAAGATAAGCCCCACAACTGTAGTGTGTGCGGTAAAGCTTTCAAATGCAGAAGCACCTTCATAAACCACATGAGAATGCACACTGGTGACCGGCCACACCAGTGTCCTGTTTGTGGCAAGCAGTTCACTACGCTGGGCAATCTTATTGTGCATAGGAGAACACACAGTGGAGAAAAACCATACAAATGTGAGACGTGCTTGAAAGCATTTAGTGACAAAGGTAACCTCACGGCACATCAGGCTGTTCACTCAGGAGAGAAACCTCACATCTGTTCGACATGTGCACAACCTTTTAAATATCCCAGCAGTTTGAAACGGCATATTAGAAAACGCCATGCAGGTGAAGGACTGCCCATTAATAAAGTAAACTTATACTAA
Protein Sequence
MNETMVLNFSRICRLCLSDHKTLLPLFNTAEKVQEKIHTISPTIEVYAGDGLPAQICKECVHQVNISYKFILQCERSNATLRHHLNNQRPHDTPVQVVLKEEPSLCDDTESTNELLQSTGNGNQENALGSETDVTVDEDGDSDSSDVSLKDGSVSPDEDAVEPENEVNTDTWDKTETCDTSLGRKSSRVMKDEDIIAPYPHTKGRRNTPPTDTSVYHLKHEDISVSDQCIKKTSSGSTPTPATLTQDMKHEDVSVPDSCISAAKSTLPSSTSHYVDNNGETEQYACDVCNKSFNTEKDMKKHSLVHPEDKPYSCSECGSSFQYKSSLTNHTVLHSQDSHMCTECGKVFHSKSNLTQHLASHSEARPHLCSLCGKSFKYKSNLSQHTALHARDMPVQCNVCNKHFGSKTDLMIHILSHLEEMPHQCSECGKCFNSESQLSDHQALHAETNQHGCSVCGKYFKTKYNLTVHQALHTKDRSHLCTVCGKAFKYKSNLLEHSALHTEDKPFLCTQCGKAFGGKSKYSSHLATHSEDRPYQCSICGKCFKHKSNLCNHKALHVENGPHLCNVCGKSFSCKSKFTSHVASHSEERPHQCPVCGKSFKYKSNLCNHKALHVENGPHMCTFCSKSFGTKSNLIKHIAIHSEERPFQCSVCGKGFKYMSNLCNHKALHVENGPHLCTVCGKSFSCKSNLMKHVAVHSEARPYQCPICGKGFKYMSNLCNHKTLHTQKSPYLCAVCGKSFSSKSNLMTHSASHSDDRRHQCSICGKSFKFKSSLTSHQALHSQDKPHNCSVCGKAFKCRSTFINHMRMHTGDRPHQCPVCGKQFTTLGNLIVHRRTHSGEKPYKCETCLKAFSDKGNLTAHQAVHSGEKPHICSTCAQPFKYPSSLKRHIRKRHAGEGLPINKVNLY

Similar Transcription Factors

Sequence clustering based on sequence similarity using MMseqs2

100% Identity
iTF_00396473;
90% Identity
-
80% Identity
-