Basic Information

Transcription Factor Domain

TF Family: zf-GAGA
Domain: zf-GAGA domain
PFAM: PF09237
TF Group: Zinc-Coordinating Group
Description: Members of this family bind to a 5'-GAGAG-3' DNA consensus binding site, and contain a Cys2-His2 zinc finger core as well as an N-terminal extension containing two highly basic regions. The zinc finger core binds in the DNA major groove and recognises the first three GAG bases of the consensus in a manner similar to that seen in other classical zinc finger-DNA complexes. The second basic region forms a helix that interacts in the major groove recognising the last G of the consensus, while the first basic region wraps around the DNA in the minor groove and recognises the A in the fourth position of the consensus sequence [1].
Hmmscan Out: # of c-Evalue i-Evalue score bias hmm coord from hmm coord to ali coord from ali coord to env coord from env coord to acc

1 10 0.025 32 4.1 0.0 21 45 39 63 36 70 0.86

2 10 0.0016 2 8.0 0.0 20 46 66 92 59 98 0.80

3 10 0.16 2.1e+02 1.5 0.3 21 30 95 104 91 109 0.85

4 10 0.14 1.8e+02 1.7 0.0 21 44 151 174 144 178 0.80

5 10 0.018 23 4.6 0.1 21 43 179 201 170 206 0.86

6 10 0.046 59 3.3 0.0 20 47 206 233 201 239 0.80

7 10 0.17 2.1e+02 1.5 0.0 22 45 236 259 232 266 0.83

8 10 0.0013 1.7 8.2 0.0 22 47 264 289 255 294 0.84

9 10 0.19 2.4e+02 1.3 0.0 21 46 291 316 288 318 0.89

10 10 0.83 1.1e+03 -0.7 0.4 27 45 325 343 322 349 0.53

#	of	c-Evalue	i-Evalue	score	bias	hmm coord from	hmm coord to	ali coord from	ali coord to	env coord from	env coord to	acc
1	10	0.025	32	4.1	0.0	21	45	39	63	36	70	0.86
2	10	0.0016	2	8.0	0.0	20	46	66	92	59	98	0.80
3	10	0.16	2.1e+02	1.5	0.3	21	30	95	104	91	109	0.85
4	10	0.14	1.8e+02	1.7	0.0	21	44	151	174	144	178	0.80
5	10	0.018	23	4.6	0.1	21	43	179	201	170	206	0.86
6	10	0.046	59	3.3	0.0	20	47	206	233	201	239	0.80
7	10	0.17	2.1e+02	1.5	0.0	22	45	236	259	232	266	0.83
8	10	0.0013	1.7	8.2	0.0	22	47	264	289	255	294	0.84
9	10	0.19	2.4e+02	1.3	0.0	21	46	291	316	288	318	0.89
10	10	0.83	1.1e+03	-0.7	0.4	27	45	325	343	322	349	0.53

Coding Sequence: ATGGGTCCAACCATGAAAGGAGCACTGAACAATGCCTGTACGAGACTTTGCGAGGTGTGCGGTAAAACTTTTACCAGAGCTGCACATTTTAAAACGCACCAACTTGTTCATACGGGGGAAAAACCCTTTAAGTGCTCAGTATGTCATAAAGGTTTCACATCTTCTAGTAACATTACAGAGCATATGAGGACCCATACAGGGGAGAAACCCTTTGAGTGCCCAGTGTGTCGAAAAGGTTTTATATCTTCTAGTAACATCACGAAGCACATGCGGACCCATACTGGGGAGAAACCCTTTGAGTGCCCAGTGTGTCGAAAAAGTTTTATATCTCTTGGTGACCGCACAAAGCACATGATAACACACACGGGGGATAAACCCTTCGAGTGCTCAACTTGTTCTCAAGCgtttagcaaaaaaatcaatcttataACACACATACGGTCTCACACTGGGGAAAAACCCTTTAAATGCTCAGTGTGTCAGAAAGGTTTTACATCTTCTAGTGATGTCACGAAGCACATGCGGACCCATACGGGAGAGCGTCCTTACAAGTGCTCGGTGTGTCAAATGGGTTTTAAATCTTCTAGTAACCTCACATCCCACAGGAGGACCCATACAGGGGAGAAACCATTTAAGTGCTCAGTATGTCATAAAGGTTTTACATCTTCTAGTAATCGCACAAATCACATGTGGATCCACACGAGGGAGAAACCCTTCAAATGCTCGGTATGTCAAATGGGTTACAAATCTTCTAGTTACCTCACATCCCACATGAGGACCCATACAGGGAAAAAACCCTTGGAGTGTTCAGTATGTCAAAAAGGTTTTACATCGTCTAGAAATCTCACAAAGCACATGTGGATCCACACGGGGGAGAAACCCTTCAAATGCTCAGATTGTCCAGAATCCTTCCGTGAAAAATGGAATCTTACGAACCACATGAGCATCCACACGGGGAtacttgataataattgtaCCATCTGCCAAAGGCCGTATATCCACCGAAGCAGTCTCAAAAGGCACATGAGAACCCATATAGAGAAAAAACTTTAA
Protein Sequence: MGPTMKGALNNACTRLCEVCGKTFTRAAHFKTHQLVHTGEKPFKCSVCHKGFTSSSNITEHMRTHTGEKPFECPVCRKGFISSSNITKHMRTHTGEKPFECPVCRKSFISLGDRTKHMITHTGDKPFECSTCSQAFSKKINLITHIRSHTGEKPFKCSVCQKGFTSSSDVTKHMRTHTGERPYKCSVCQMGFKSSSNLTSHRRTHTGEKPFKCSVCHKGFTSSSNRTNHMWIHTREKPFKCSVCQMGYKSSSYLTSHMRTHTGKKPLECSVCQKGFTSSRNLTKHMWIHTGEKPFKCSDCPESFREKWNLTNHMSIHTGILDNNCTICQRPYIHRSSLKRHMRTHIEKKL

Sequence clustering based on sequence similarity using MMseqs2