Basic Information

Gene Symbol
Aef1
Assembly
GCA_009176525.2
Location
NW:3103392-3109186[-]

Transcription Factor Domain

TF Family
zf-GAGA
Domain
zf-GAGA domain
PFAM
PF09237
TF Group
Zinc-Coordinating Group
Description
Members of this family bind to a 5'-GAGAG-3' DNA consensus binding site, and contain a Cys2-His2 zinc finger core as well as an N-terminal extension containing two highly basic regions. The zinc finger core binds in the DNA major groove and recognises the first three GAG bases of the consensus in a manner similar to that seen in other classical zinc finger-DNA complexes. The second basic region forms a helix that interacts in the major groove recognising the last G of the consensus, while the first basic region wraps around the DNA in the minor groove and recognises the A in the fourth position of the consensus sequence [1].
Hmmscan Out
# of c-Evalue i-Evalue score bias hmm coord from hmm coord to ali coord from ali coord to env coord from env coord to acc
1 4 0.0034 5.9 6.7 0.1 21 48 23 50 14 54 0.86
2 4 0.00026 0.45 10.3 0.1 21 47 51 77 49 82 0.86
3 4 0.014 25 4.7 0.0 21 47 79 105 77 110 0.84
4 4 7.9e-05 0.14 12.0 0.1 21 52 107 138 102 140 0.89

Sequence Information

Coding Sequence
atgaacGTGAAGTTGGAGTCGCATATGTCTAGAGCCCTAAGTCGTGCAATCACAATGACTGTCAGCGCTGAAAAGCCCTTCCAATGTGCTGTATGCGAAAAACAATTCCGTCAGCTTAGTACGCTCACAAACCATTATAAAATCCATACCGGAGAAAAGCCATTCAAATGTCATatATGCGATAAACGATTCAGGCAATCGAGTACGTTGACAAACCATGCAAAAATCCATACAGGAGAGAAACCGTTCAGTTGCAATTATTGCGCAAAACTATTCCGACAACTAAGCACACTAATCAATCATACAAAGATCCACACGGGCGAAAAACCTTTTGAATGCGCTGTGTGCAAAAAACAATTTAGACAGTCTAGTACTCTAAATAATCATATTAAAATCCATGTATCGGATAAGCCATTCTTGCAAGAGTTGCAGGAAGCCCACAGTCGATTTAAGCAGGAGCCACAACAAGACGCAACTATGTGA
Protein Sequence
MNVKLESHMSRALSRAITMTVSAEKPFQCAVCEKQFRQLSTLTNHYKIHTGEKPFKCHICDKRFRQSSTLTNHAKIHTGEKPFSCNYCAKLFRQLSTLINHTKIHTGEKPFECAVCKKQFRQSSTLNNHIKIHVSDKPFLQELQEAHSRFKQEPQQDATM

Similar Transcription Factors

Sequence clustering based on sequence similarity using MMseqs2

100% Identity
iTF_01351110;
90% Identity
iTF_01351110;
80% Identity
iTF_00367579;