Canc009063.1
Basic Information
- Insect
- Conomelus anceps
- Gene Symbol
- ZNF219
- Assembly
- GCA_948455865.1
- Location
- OX418224.1:39779886-39787701[+]
Transcription Factor Domain
- TF Family
- zf-C2H2
- Domain
- zf-C2H2 domain
- PFAM
- PF00096
- TF Group
- Zinc-Coordinating Group
- Description
- The C2H2 zinc finger is the classical zinc finger domain. The two conserved cysteines and histidines co-ordinate a zinc ion. The following pattern describes the zinc finger. #-X-C-X(1-5)-C-X3-#-X5-#-X2-H-X(3-6)-[H/C] Where X can be any amino acid, and numbers in brackets indicate the number of residues. The positions marked # are those that are important for the stable fold of the zinc finger. The final position can be either his or cys. The C2H2 zinc finger is composed of two short beta strands followed by an alpha helix. The amino terminal part of the helix binds the major groove in DNA binding zinc fingers. The accepted consensus binding sequence for Sp1 is usually defined by the asymmetric hexanucleotide core GGGCGG but this sequence does not include, among others, the GAG (=CTC) repeat that constitutes a high-affinity site for Sp1 binding to the wt1 promoter [1].
- Hmmscan Out
-
# of c-Evalue i-Evalue score bias hmm coord from hmm coord to ali coord from ali coord to env coord from env coord to acc 1 12 8.3e-06 0.0041 19.9 0.9 2 23 687 708 687 708 0.97 2 12 2.7e-07 0.00013 24.6 1.7 1 23 714 736 714 736 0.98 3 12 1.4e-05 0.007 19.1 4.4 1 23 742 764 742 764 0.99 4 12 1.6e-05 0.0079 19.0 0.7 2 23 771 792 770 792 0.96 5 12 4.4e-05 0.021 17.6 0.2 1 20 798 817 798 819 0.95 6 12 0.0025 1.2 12.1 1.9 1 23 825 848 825 848 0.91 7 12 2.8e-05 0.014 18.2 1.4 3 23 856 876 855 876 0.97 8 12 5.8e-06 0.0028 20.4 1.2 1 23 882 904 882 904 0.98 9 12 4.7e-05 0.023 17.5 1.4 1 23 910 932 910 932 0.98 10 12 4.1e-06 0.002 20.8 1.1 1 23 938 960 938 960 0.98 11 12 0.87 4.2e+02 4.1 1.3 2 23 968 986 967 986 0.91 12 12 1.3e-05 0.0062 19.3 0.3 1 23 992 1015 992 1015 0.97
Sequence Information
- Coding Sequence
- ATGGACAAAACTAGTCGTCAGTTACAAAGTGACAAAGCTCAAGCCATGGAATCAGTTTCTATGCCTAATAACACTATTATGTCATCCTCTAACCTAACACAAGTGAACACTACTATGAGTGTTGGAAACATTCAACCTCCTGGGCAAACTAGTGGAAGTAATAATGTGTTCAATGGATTCTACAGCTCTGGATTCAACTCGTCCATCAACAATTTAGAGGCCAGTCTTCAGTGGTTATCTGAAACAAGAGTTCCAAATAATTCCTTGATGACTGACAAAAATTTGAACTGTAATGCCACACATTCAGTGCCATCGCATTCTTGCTGTGTAAATAGAATAGATAACTTAGGGATGTGTTCACCGCTTCCAGGAGAAACCTACAGATCAAGTTGTCGTGATAGTAATTTTCAAACCAGGCCATCAAGTCTATCTTTGAATGTCATGGATTCTGTCCAAAGCTGGTTCAACCTACAACCAATTCAATCAAATCAGCAATACAGTGGAAAATTTCCCGATCAGAATCTGAACTGTGCGCAAATGAACTTACCAGTCCTTGAACAATCAGATTTGAAACAGGCTGATATCAATATTACAATGCCAGATGCTTACTTCGAACCACATTTGAGTAGTAATGCCAATAAATCAATAGGACCTAATCTGAATGAAATCAGTGCCAAGATTCCTGACGTTAATGATGTTCAATCCAGTAGTATGAAAGTTCAAAACAATAATTTCCAATCAACCATATTACCTAGAGAATGGAAACAAACATCAAGTTTACAAGCTAACTACGTTTCTAGTCCAACTTTTTTTAATTCTATCAGTGATTCTCCAGATCATTTCATTTATTCCTTACCCCCACCGACTAGTTCATATTGTATGCCAACAACTGATAATATTGCTAGCTCTTCAAATAAGCAGCAGAACTGTTATCAGCAGCCTGATAAGCATCAAAACACTATTCCTCAATTAAATTGTAGACCGAATTATATTGATCAAACTTCACAGTTGAAAGTTCTTGGTTTGCCTCCCTTACAACAATCTACCGACAGAAATGAAAAGACCTTTTACGAGAAACCAGTCACAATGGAGGGTGTAATGAGTAGTAGTGATGTCATGAAAACTATTCAGTCGTCCTCATCTGCTCAGAAAGACAATGAAGTGAAAATGAACTCCACTAGAAAATTTCCCGATTCTTTAGCCAATTACACTTTGCCTTATTTACCGGATGTAGGAGCATCCAATGAGACAATAGTTCACAGTGGCATCAGTCAAAAGTTACCTGAACTCTCAAAAACCATTGAACAAAACTTGAACGATGACAGTTCGAGTGGATCGGATGAAAGTAACATCATTGTTGAGGAATCTGATGAAACTGAAGAAATGGAAAGCGTTACATCAATAGAAGAGATGAAAAAGAGTTTACTGTCTTCTGTTGAGTTGAGGTGTCTGGTGTGCAATGTGAAATCATCTCAGCAAACGCCGGCCACCCAGTTCATTCACATGAACGATTCGTTCCCTGTGACGTCAGCCTCACGCACTCCAGTCGCCTCCAAACTCATCCAGATCATCCCCGCCGATCTCAAACACTTCCTCAAGCTCCATAACAGTTTCATGTGCCGACGCTGTCTCAATCTAATTGAAACTGTCGAGGTGCTCGAGGTTAAACTGACCTCAGTAAAGCAGACACTTAGTGAGAACTTCTCAAAGACCATTCAGTGCTTCTTACCGGCAACACCAATTATTGAGATTGAGGACGGAAAAGCGGAAATTGTTGACAAAGAAATTATCAAATCGATTGAGAAGACTGGGTTGGAAGGTGCACTGGTCAACTTCAGTGAAACTACGCTCTATCTTGATATTCAGCCGGCAAAAAAGGTTTGTAGGTGCTCCAATGTAGTCACTTTGATTAAAACTCATAAAAGGGTCGCCTGTGTGATTGTAGACAATCTGGAAGAAGTAgacgatgtggatgatggtattgatgataatacagacacaagagatgatttttctgatgaaggtgatgaggctgatgatgatgacggtgaAAAAAGGACTTGCAACATCTGTGGTAAAACTCTATCAAGCGCTAAGACAttcaaaaggcacatggaaattcatacgggtgcctttagtttctactgtgaaacgtgtggcaagggatttaataagaaatcatctttagaaacgcatctacgaacgcatagtggggacaatcggtttcagtgtgagaagtgtgGTCAAACCTATAGTCAAAAACACCGGCTGGAAACGCATCTGCGAAAGCATGCGGCTGATTTCAGTCTGCATTGTGACGTGTGTGGCAAGGGCTTTGTACAGAAACGTTTGCTGGAAAAACATGCACTGACACACACTGACTATCGTCCGTTTGTTTGTGAGAGATGTGGTTTCACATTTTCTAAAAAATCCGGTTTGAAAGCACATCTGGATGTTTGTGAGAAGAAAGAATTCCCATGTGATTGTTGTTCGCAGGTTTTCACATCACAAGCGAATCTCAAAAAACACAAAGTTTCTGAACACTGTGACGAACCGCCTGCCTGCTGTGAAATCTGCGGTAAAATATTTGCTCAGCGCAAAGACTTGAAGCCACACATGCGTTCACATTCGGACGACAAACCGTTCCGTTGCGAAATCTGTGATAAATCGTACAAAACTCGAGGTGACCTGAACTATcattccaaaatacacaacgtcgacaaactgttcaaatgttcaatttgtgataaatccttcgcccggaaacaggtatatgacgatcacatgtcaaagcatgctggcaatcgcaactacaagtgtacagagtgcgacagggcgttctttgagaaaggtaaactccagaaacatatgtccattcataatggtgGTGTAAAGCGAAAGACATGTCCCGTTTGCAATAAGGAAGTGCAGCATATGAATGTTCATATGAGGATACATTCTGGTGAAAAGCCGTATGTGTGCAAGATCTGTGGCCTTGCTTTCAGTATTAACCGTACGTTGATGAGGCATATACAGAGTAAGCATTATACTTCAGCGTAG
- Protein Sequence
- MDKTSRQLQSDKAQAMESVSMPNNTIMSSSNLTQVNTTMSVGNIQPPGQTSGSNNVFNGFYSSGFNSSINNLEASLQWLSETRVPNNSLMTDKNLNCNATHSVPSHSCCVNRIDNLGMCSPLPGETYRSSCRDSNFQTRPSSLSLNVMDSVQSWFNLQPIQSNQQYSGKFPDQNLNCAQMNLPVLEQSDLKQADINITMPDAYFEPHLSSNANKSIGPNLNEISAKIPDVNDVQSSSMKVQNNNFQSTILPREWKQTSSLQANYVSSPTFFNSISDSPDHFIYSLPPPTSSYCMPTTDNIASSSNKQQNCYQQPDKHQNTIPQLNCRPNYIDQTSQLKVLGLPPLQQSTDRNEKTFYEKPVTMEGVMSSSDVMKTIQSSSSAQKDNEVKMNSTRKFPDSLANYTLPYLPDVGASNETIVHSGISQKLPELSKTIEQNLNDDSSSGSDESNIIVEESDETEEMESVTSIEEMKKSLLSSVELRCLVCNVKSSQQTPATQFIHMNDSFPVTSASRTPVASKLIQIIPADLKHFLKLHNSFMCRRCLNLIETVEVLEVKLTSVKQTLSENFSKTIQCFLPATPIIEIEDGKAEIVDKEIIKSIEKTGLEGALVNFSETTLYLDIQPAKKVCRCSNVVTLIKTHKRVACVIVDNLEEVDDVDDGIDDNTDTRDDFSDEGDEADDDDGEKRTCNICGKTLSSAKTFKRHMEIHTGAFSFYCETCGKGFNKKSSLETHLRTHSGDNRFQCEKCGQTYSQKHRLETHLRKHAADFSLHCDVCGKGFVQKRLLEKHALTHTDYRPFVCERCGFTFSKKSGLKAHLDVCEKKEFPCDCCSQVFTSQANLKKHKVSEHCDEPPACCEICGKIFAQRKDLKPHMRSHSDDKPFRCEICDKSYKTRGDLNYHSKIHNVDKLFKCSICDKSFARKQVYDDHMSKHAGNRNYKCTECDRAFFEKGKLQKHMSIHNGGVKRKTCPVCNKEVQHMNVHMRIHSGEKPYVCKICGLAFSINRTLMRHIQSKHYTSA
Similar Transcription Factors
Sequence clustering based on sequence similarity using MMseqs2
- 100% Identity
- iTF_01354019; iTF_00857886;
- 90% Identity
- -
- 80% Identity
- -