Basic Information

Insect: Columbicola columbae
Gene Symbol: Hr39
Assembly: GCA_016920875.1
Location: JADMLL010000010.1:11609195-11626438[-]

Transcription Factor Domain

TF Family: SF-like
Domain: zf-C4|SF-like
PFAM: AnimalTFDB
TF Group: Zinc-Coordinating Group
Description: The ligand binding domain of nuclear receptor steroidogenic factor 1 (SF-1): SF-1, a member of the nuclear hormone receptor superfamily, is an essential regulator of endocrine development and function and is considered a master regulator of reproduction. Most nuclear receptors function as homodimer or heterodimers, however SF-1 binds to its target genes as a monomer, recognizing the variations of the DNA sequence motif, T/CCA AGGTCA. SF-1 functions cooperatively with other transcription factors to modulate gene expression. Phospholipids have been determined as potential ligands of SF-1. Like other members of the nuclear receptor (NR) superfamily of ligand-activated transcription factors, SF-1 has a central well conserved DNA binding domain (DBD), a variable N-terminal domain, a flexible hinge and a C-terminal ligand binding domain (LBD). [1, 8, 3, 11, 6, 5, 12, 10, 9, 2, 4, 7]
Hmmscan Out: # of c-Evalue i-Evalue score bias hmm coord from hmm coord to ali coord from ali coord to env coord from env coord to acc

1 3 0.015 1.3e+02 1.7 2.0 93 173 197 301 118 379 0.59

2 3 3.3e-09 2.7e-05 23.6 0.0 1 32 495 528 495 548 0.80

3 3 1.5e-71 1.3e-67 229.0 0.0 160 408 551 806 540 806 0.91

#	of	c-Evalue	i-Evalue	score	bias	hmm coord from	hmm coord to	ali coord from	ali coord to	env coord from	env coord to	acc
1	3	0.015	1.3e+02	1.7	2.0	93	173	197	301	118	379	0.59
2	3	3.3e-09	2.7e-05	23.6	0.0	1	32	495	528	495	548	0.80
3	3	1.5e-71	1.3e-67	229.0	0.0	160	408	551	806	540	806	0.91

Sequence Information

Coding Sequence: ATGGACGCGACTGCCACAAGCGCTAGTTGGGCTCAAACAGCAAGCAGACTTGTATCACAAAGCTCTCCGACAAATGGGGTAGTGTCAGTCGTTGTCGACTCGAGAAGCGAAGGTCCAAGTGTTTTCGCCGTCAAAGAGGAACATATCGTTGGTAGAGGCACTTCGATCACTTGCGGAGGAGTAACAGTTACTTCAATAAATGTCACTCAAGATGAGGAACAAGAGTTCGGACAAAACGTTAAAAATACGACATATTTCGAGAAGGACAAATCGGAAGTGGGCGTAAAATGTGAACCCCTTACTGCGAACAATTACAACGATGACGATTCCGGATCGGATTCGGAAGTGAGCAAGATTGATTTTAGCGGCGTTCACCTAAGAATAAAGAAAAAGAGGAGCAAGAAAAATGATGAAAAGTGTCAAGAAATGCTCGAAAGCGAAGAGCCGGAGAGGCCAATGTCTTGGGAAGGGGAGCTTTCAGATACTGAAATGTCAATTGTCACGGGAGGAAGGCACATGAGAGATGACCTGATGGGTGAAGTTCAGTTGTCACCGCAACGCTTGCCTAAAACTGAACACTTTAATGACACTATAATGGGGCCGGGAAGACTGAAACAGGAACCAGATGCCAGTGATTCAATGGGTGGTTATTCAGCAGCTTCCAGAGAATTACCTTTGCTTGTGGATAAACTTTTGGGTGGATACACCACTCCCTCGCAGAGTCCTATCCTTCAGCAAAGACAGCATCATACATTGACGAAACAGCATTCTCATTTGGGTGCTCTCCCTCCGAACCCATCTCCCGATTCAGCCATACATTCCGCGTATTCGTATTCGTCGCCGGCTGCTTCTCCAGCAGCCTCACGTCACCTCCCCTCAAGCGGATTTTCGTCCCCTTTCACTCCTTCACTGTCGCGAAACAATTCGGATGCGAGTCAGTATGGCGGATCCCAGCATTCTTCTTGCTACAGCTATAACAGTGAGAATTTCTCGAGTCCTACTCATTCTCCGATACAAAGCAGACATCTCCTTGGATACTCAAAAGTGGACAGTAGTCCCATGCACACTGTCGCAGGGAGTGTCGGGTACGGTTCCCGCGGAATGACATCCTCCCAAGGTGGAGTCGATGAATCTCCTCATTTAGATAGTGAAAGAGATGAGGAGAGGGATCCTTGCCTCGAAGAAAAAATGTCTTGCTTAGCATCTGATCTCTCTCAGCACTCCGCCTTGACCACTCCTCCCGGAATTTCAAGGCAACAGCTGATTAATAGCCCTTGTCCCATATGCAGTGACAAGATATCTGGATTTCATTACGGTATATTCAGCTGTGAGTCTTGTAAAGGATTCTTCAAAAGAACTGTTCAGAATAGAAAGAATTACGTTTGCTTGAGAGGATCCCAATGCCCGGTGACTATCGCAACCCGGAAGAAGTGTCCGGCTTGCAGGTTTGAAAAATGTCTGAAGATGGGAATGAAACTGGAGGCAATACGTGAAGACAGAACAAGAGGTGGACGAAGCACATATCAGTGTTCGTATAGTGTACCCTCTTCGTTGCTCCAGTCGAGTGACTCCATTCAAAAGCTGTCGAATAGTCTTGCAACTGGTGAAACTCTAGTCAAGCTAGAAACACCGCACTTAGGTTCGCCCAATTCGAATTTGGATTCAAGACTGTTGCCAGTTCCGCAACTATTGCAGGAAATCATGGATGTCGAACACTTGTGGCATTACAACGAGAGGGAAATGCTCGGGTCTCCGCTTAACAATCACCGTCAGTCTCCCTCATCGACCCCCTCTTCTCCATCTCAACCCAGCACGGATTCAAATCCCGACTTCCTTTCTAATTTGTGCAATATCGCTGATCATCGTCTGTACAAAATAGTTAAGTGGTGCAAGAGCTTGCCCCTGTTCAAAAACATATCGATCGATGATCAAATATCCTTGTTAATCAATTCGTGGTGCGAACTTCTCCTGTTTTCCTGCTGTTTTCGATCCATGTCTTCGCCAGGGGAAATTCGAGTTTCCCTAGGAAAATCCATTTCATTGTCGAAGGCAAAAGATCTTGGGTTCGGGCCATGCATCGAAAGGATGTTGAACTTTACTCAGCATCTTCGAAGACTCCGATTGGACAAATATGAATACGTTGCGATGAAGGTGATCGTCCTATTAACCAGTGATGTGAACGATTTGAGAGAACCCGAAAAGGTGAGAGCATCTCAAGAGAAAGCTCTTCAGGCTCTCCAACATTATACTCTTGCTCACTATCCTGACATCCCGTCAAAGTTTGGAGAATTGCTTCTGAGAATTCCAGAACTCCAGAGAACTTGTCAGGTTGGAAAGGAAATGCTGTCGATCAAAAACAGAGACGGTGAAGAAGGTCCCAGCTTCAACCTTTTGATGGAGCTGTTGAGAGGAGATCATTAA
Protein Sequence: MDATATSASWAQTASRLVSQSSPTNGVVSVVVDSRSEGPSVFAVKEEHIVGRGTSITCGGVTVTSINVTQDEEQEFGQNVKNTTYFEKDKSEVGVKCEPLTANNYNDDDSGSDSEVSKIDFSGVHLRIKKKRSKKNDEKCQEMLESEEPERPMSWEGELSDTEMSIVTGGRHMRDDLMGEVQLSPQRLPKTEHFNDTIMGPGRLKQEPDASDSMGGYSAASRELPLLVDKLLGGYTTPSQSPILQQRQHHTLTKQHSHLGALPPNPSPDSAIHSAYSYSSPAASPAASRHLPSSGFSSPFTPSLSRNNSDASQYGGSQHSSCYSYNSENFSSPTHSPIQSRHLLGYSKVDSSPMHTVAGSVGYGSRGMTSSQGGVDESPHLDSERDEERDPCLEEKMSCLASDLSQHSALTTPPGISRQQLINSPCPICSDKISGFHYGIFSCESCKGFFKRTVQNRKNYVCLRGSQCPVTIATRKKCPACRFEKCLKMGMKLEAIREDRTRGGRSTYQCSYSVPSSLLQSSDSIQKLSNSLATGETLVKLETPHLGSPNSNLDSRLLPVPQLLQEIMDVEHLWHYNEREMLGSPLNNHRQSPSSTPSSPSQPSTDSNPDFLSNLCNIADHRLYKIVKWCKSLPLFKNISIDDQISLLINSWCELLLFSCCFRSMSSPGEIRVSLGKSISLSKAKDLGFGPCIERMLNFTQHLRRLRLDKYEYVAMKVIVLLTSDVNDLREPEKVRASQEKALQALQHYTLAHYPDIPSKFGELLLRIPELQRTCQVGKEMLSIKNRDGEEGPSFNLLMELLRGDH

Similar Transcription Factors

Sequence clustering based on sequence similarity using MMseqs2

100% Identity: iTF_00362587;
90% Identity: iTF_00362587;
80% Identity: iTF_00362587;