Basic Information

Transcription Factor Domain

TF Family: zf-GAGA
Domain: zf-GAGA domain
PFAM: PF09237
TF Group: Zinc-Coordinating Group
Description: Members of this family bind to a 5'-GAGAG-3' DNA consensus binding site, and contain a Cys2-His2 zinc finger core as well as an N-terminal extension containing two highly basic regions. The zinc finger core binds in the DNA major groove and recognises the first three GAG bases of the consensus in a manner similar to that seen in other classical zinc finger-DNA complexes. The second basic region forms a helix that interacts in the major groove recognising the last G of the consensus, while the first basic region wraps around the DNA in the minor groove and recognises the A in the fourth position of the consensus sequence [1].
Hmmscan Out: # of c-Evalue i-Evalue score bias hmm coord from hmm coord to ali coord from ali coord to env coord from env coord to acc

1 7 6.5e-06 0.078 13.5 0.6 5 49 22 70 20 74 0.82

2 7 0.046 5.5e+02 1.2 0.0 14 36 82 104 77 106 0.77

3 7 0.038 4.6e+02 1.5 0.0 14 36 117 139 114 141 0.79

4 7 0.036 4.3e+02 1.5 0.0 14 36 152 174 147 176 0.80

5 7 0.036 4.3e+02 1.5 0.0 14 36 187 209 182 211 0.80

6 7 0.04 4.7e+02 1.4 0.0 14 36 222 244 219 246 0.79

7 7 0.037 4.4e+02 1.5 0.0 14 36 257 279 253 281 0.80

#	of	c-Evalue	i-Evalue	score	bias	hmm coord from	hmm coord to	ali coord from	ali coord to	env coord from	env coord to	acc
1	7	6.5e-06	0.078	13.5	0.6	5	49	22	70	20	74	0.82
2	7	0.046	5.5e+02	1.2	0.0	14	36	82	104	77	106	0.77
3	7	0.038	4.6e+02	1.5	0.0	14	36	117	139	114	141	0.79
4	7	0.036	4.3e+02	1.5	0.0	14	36	152	174	147	176	0.80
5	7	0.036	4.3e+02	1.5	0.0	14	36	187	209	182	211	0.80
6	7	0.04	4.7e+02	1.4	0.0	14	36	222	244	219	246	0.79
7	7	0.037	4.4e+02	1.5	0.0	14	36	257	279	253	281	0.80

Coding Sequence: ATGGGAGGGAATGAGGATAGGGAAAGAGAGGATGGGTCTACAAAGGAGTTTGTAGAATATTGCAGGAAGCGACATCCATCAACAACGTGGAATTACTTTCTAAAATCCAGCGACCAACAGTCTGCTAAGTGCAAGATATGTTCTCGAGTTATAAAAACCACCGGATCATCCACTAGTGGGTTACATGCACATTTGCGGTCGAGACATAAGATCAAATTGGAATTTGCTGAAAAATGTTCTGGAAAGACCTCGTCACGAGTGCAGAGTGAAGAACATACGACTCTAGATACAAATTTAGTAATAGTTAAACAAGAACCAATTACTGTCGAGATCTCGTTTGAAGGTGGAAAGGCCTCGTCACGAGTCCAGAGTGAAGAACATACGACTATAGATACAAATTTAGTAATAGTTAAGCAAGAACCAATTACTGCCGAGAACTCGTTTGAAGGTGGAAAGGCCTCGTCACGAGTCCAGAGTGAAGAACATACGACTATAGATACAAATTTAGTAATAGTTAAGCAAGAACCAATTACTGCCGAGAACTCGTTTGAAGGTGGAAAGGCCTCGTCACGAGTCCAGAGTGAAGAACATACGACTATAGATACAAATTTAGTAATAGTTAAGCAAGAACCAATTACTGCCGAGATCTCGTTTGAACGTGGAAAGGCCTCGTCACGAGTCCAGAGTGAAGAACATACGACTATAGATACAAATTTAGTAATAGTTAAGCAAGAACCAATTACTGCCGAGGACTCGTTTGAAGGTGGAAAGGCCTCGTCACGAGTCCAGAGTGAAGAACATACGACTATAGATACAAATTTAGTAATAGTTAAGCAAGAACCAATTACTGCCGAGATCTCGTTTGAAGGTGAAGTACAAAACGATGAATATATTTATGATAGCATATTGCAAAGCAAATAA
Protein Sequence: MGGNEDREREDGSTKEFVEYCRKRHPSTTWNYFLKSSDQQSAKCKICSRVIKTTGSSTSGLHAHLRSRHKIKLEFAEKCSGKTSSRVQSEEHTTLDTNLVIVKQEPITVEISFEGGKASSRVQSEEHTTIDTNLVIVKQEPITAENSFEGGKASSRVQSEEHTTIDTNLVIVKQEPITAENSFEGGKASSRVQSEEHTTIDTNLVIVKQEPITAEISFERGKASSRVQSEEHTTIDTNLVIVKQEPITAEDSFEGGKASSRVQSEEHTTIDTNLVIVKQEPITAEISFEGEVQNDEYIYDSILQSK

Sequence clustering based on sequence similarity using MMseqs2