Basic Information

Insect: Coenonympha glycerion
Gene Symbol: Hr39
Assembly: GCA_963855885.1
Location: OY979630.1:3743335-3753948[-]

Transcription Factor Domain

TF Family: SF-like
Domain: zf-C4|SF-like
PFAM: AnimalTFDB
TF Group: Zinc-Coordinating Group
Description: The ligand binding domain of nuclear receptor steroidogenic factor 1 (SF-1): SF-1, a member of the nuclear hormone receptor superfamily, is an essential regulator of endocrine development and function and is considered a master regulator of reproduction. Most nuclear receptors function as homodimer or heterodimers, however SF-1 binds to its target genes as a monomer, recognizing the variations of the DNA sequence motif, T/CCA AGGTCA. SF-1 functions cooperatively with other transcription factors to modulate gene expression. Phospholipids have been determined as potential ligands of SF-1. Like other members of the nuclear receptor (NR) superfamily of ligand-activated transcription factors, SF-1 has a central well conserved DNA binding domain (DBD), a variable N-terminal domain, a flexible hinge and a C-terminal ligand binding domain (LBD). [1, 8, 3, 11, 6, 5, 12, 10, 9, 2, 4, 7]
Hmmscan Out: # of c-Evalue i-Evalue score bias hmm coord from hmm coord to ali coord from ali coord to env coord from env coord to acc

1 3 5 2.8e+04 -6.7 11.2 49 170 187 311 128 356 0.49

2 3 7.2e-08 0.00041 20.5 0.1 1 21 437 457 437 468 0.91

3 3 6.4e-65 3.6e-61 208.4 0.0 152 408 490 755 465 755 0.83

#	of	c-Evalue	i-Evalue	score	bias	hmm coord from	hmm coord to	ali coord from	ali coord to	env coord from	env coord to	acc
1	3	5	2.8e+04	-6.7	11.2	49	170	187	311	128	356	0.49
2	3	7.2e-08	0.00041	20.5	0.1	1	21	437	457	437	468	0.91
3	3	6.4e-65	3.6e-61	208.4	0.0	152	408	490	755	465	755	0.83

Sequence Information

Coding Sequence: ATGATGTCGACAAGCGAGGGGGAGGCGGTGAAAGTGGAGGGTGGGCATGTCTCCGTCACCACCATCAGCATGTCGGGCCCAGAAACCAGCAATGGTCGATTCTCGTACAGCTCGAGCGGCGTCCGCATCAGCGTGTCCTCCGAGCCGCACGATGAGGACTCCACTGACGCGGAGATATCCAAGATCGACTTCACGCAGCATCAGTACGAGGTGAACATGCGCAACAAAAAGAAGCGGTCGTCGAGCGGGCAGTGCGAGCAGGCCGTGGAGCAGGAGCGGCCCATGTCGTGGGAGGGGGAGCTCTCAGACTCCGAGATGGTCATCGACACCAGCGTCAACAACGATGAAAACAGCAGTTCCCTGGACTTGCAGTCGTCGCATGACTCCATAGACACTCTGCGAAATGTGACCATCAAGACGGAACCGCTCAAGACTGAGACCTTCCAGAGCTTGGATGACCAGCGGGTGCTGGATCTCAAGTACACGATGCCGCTGCAGTCGCaccagcggagtcttagtatgAACAGGATATCGGTGCTAACGGACAACGCGTCGCTGACGCTGGCCAGGCGGCCGTCCTCTCCCACGAGCAGTGCCAAGTCCGCCCACTCCGACCAGTACGAGGGGCAGCTCACGCAGAACCCCGCTGTAGAAGTTCAGAACTTGACTATTAAAAAGGAGCAACTATCTGAGCTGAAATGCGAGCCATCAGTGGGCATGGAGAAGCTGCTGGGGCTGCACGGCTCGCCGCTGCTGGGCCGGCTGCCGAGAGTGCAGTCCAGCGCCAGCACGGACTCCGCTGTACACTCTATGTACACGCATAGCGTGTACAGCAGCCCGTCGGCGAGCCCGCGCCCGTCGCGGCACTACACGCCGTCCCTGTCGCGCAACAACAGCGACGCCTCGCACTCTTCCTGCTACTCCTACAGCTCGGAGTTCTCGCCCACGCATTCCCCCGTTCAGAGTCGACATCCGCACGTAGTGTACCGCGAGGCTACTGTGTTCCCGGCCTCACCTGCTCACGATGAGGACACTGACGCGACGGACGACCGCCTCCATCATCACCAGGGTATCAGCAGGCAGCAACTCATCAACAGCCCGTGCCCAATCTGCGGTGACAAAATCAGCGGGTTCCACTATGGGATATTCTCCTGCGAGTCCTGCAAGGGCTTCTTCAAGCGCACCGTGCAGAACCGCAAGAACTACATGTGTCTCAGGGGTGGGAACTGCCCCGTCACGGTGGCCACCAGGAAAAAGTGTCCGGCCTGTCGGTTCGACAAGTGCCTGGGCTGTGGAATGAAACTCGAAGCGATAAGGGAAGACCGCACCCGCGGCGGTCGCTCCACGTACCAGTGCTCGTACACGCTGTCGGGCGCCGCGTCCACGGGCTCGCTGCTGTCTGCGCACGCGCCGACCACGCTGCGGCACGCCTCCAGCCTCACTTGCGTGAATGGCCCCGGATCGTACAGCAGTCGAGGGGAGTCAAGTAATAGCCGACTCACGCCTGACATACCGCCGTTATTGCAGGAAATAATGGATGTGGAACATTTATGGCAATACAACGAGTCGGAGCTCAGCCGCATGAGCAAGTCCACGGGCAGCCCCTCCGCCAACCCGCTGCTGGCGGCCAGCGGCATCACCGCGCAGAACAGCAGCGCCGACTTCCTCGCCGACCTGTGCAACATCGCCGACCACCGCCTCTACAAGATCGTCAAGTGGTGCAAGAGCCTGCCGCTCTTCAAGAACATATCCATCGACGACCAGATCTGCTTGCTGATCAACAGCTGGTGCGAGCTGCTGGTGCTGTCGTGCTGCTACCGCGGGGTCAGCACGCCGGGCGAGGTGCGCGTCGGCGGCGGCCGTGGCATCACGCTACACCAAAGTGCCAAATACGGTCTAACGCCATGTATAGAACGAATGCTCAGCTTCACGGACCACCTGAGGCGACTACGAGTTGACCGATACGAATATGTTGCGCTCAAGGTCATCGTGCTGCTCACTTCAGATGCTCCGGAACTTCGCGAAGCGGAAAAGGTGCGCGCGTCGCAGGAGAAGGCGCTCGCCGCGCTGCAGGCGTACACGGCGGCGCACTCGCCCGACACGCCCGCCAAGTTCGGCGAGCTGTTGCTGCGCATCCCCGAGCTGCAGCGGACTTGCCAGTTCTTCATGCAAGTCGGCAAGGAAATGCTCAACCCGGCCAACAAAGGCAAGGACGGCGAGGGGCCTAGCTTCAACTTGCTGATGGAGCTGTTGAGGGGCGACCACTGA
Protein Sequence: MMSTSEGEAVKVEGGHVSVTTISMSGPETSNGRFSYSSSGVRISVSSEPHDEDSTDAEISKIDFTQHQYEVNMRNKKKRSSSGQCEQAVEQERPMSWEGELSDSEMVIDTSVNNDENSSSLDLQSSHDSIDTLRNVTIKTEPLKTETFQSLDDQRVLDLKYTMPLQSHQRSLSMNRISVLTDNASLTLARRPSSPTSSAKSAHSDQYEGQLTQNPAVEVQNLTIKKEQLSELKCEPSVGMEKLLGLHGSPLLGRLPRVQSSASTDSAVHSMYTHSVYSSPSASPRPSRHYTPSLSRNNSDASHSSCYSYSSEFSPTHSPVQSRHPHVVYREATVFPASPAHDEDTDATDDRLHHHQGISRQQLINSPCPICGDKISGFHYGIFSCESCKGFFKRTVQNRKNYMCLRGGNCPVTVATRKKCPACRFDKCLGCGMKLEAIREDRTRGGRSTYQCSYTLSGAASTGSLLSAHAPTTLRHASSLTCVNGPGSYSSRGESSNSRLTPDIPPLLQEIMDVEHLWQYNESELSRMSKSTGSPSANPLLAASGITAQNSSADFLADLCNIADHRLYKIVKWCKSLPLFKNISIDDQICLLINSWCELLVLSCCYRGVSTPGEVRVGGGRGITLHQSAKYGLTPCIERMLSFTDHLRRLRVDRYEYVALKVIVLLTSDAPELREAEKVRASQEKALAALQAYTAAHSPDTPAKFGELLLRIPELQRTCQFFMQVGKEMLNPANKGKDGEGPSFNLLMELLRGDH

Similar Transcription Factors

Sequence clustering based on sequence similarity using MMseqs2

100% Identity: iTF_00642460;
90% Identity: iTF_01018623;
80% Identity: iTF_00354265;