Basic Information

Insect: Coenonympha arcania
Gene Symbol: -
Assembly: GCA_036785405.1
Location: CM072059.1:2709163-2752780[+]

Transcription Factor Domain

TF Family: MBD
Domain: MBD domain
PFAM: PF01429
TF Group: Unclassified Structure
Description: The Methyl-CpG binding domain (MBD) binds to DNA that contains one or more symmetrically methylated CpGs [2]. DNA methylation in animals is associated with alterations in chromatin structure and silencing of gene expression. MBD has negligible non-specific affinity for DNA. In vitro foot-printing with MeCP2 showed the MBD can protect a 12 nucleotide region surrounding a methyl CpG pair [2]. MBDs are found in several Methyl-CpG binding proteins and also DNA demethylase [1].
Hmmscan Out: # of c-Evalue i-Evalue score bias hmm coord from hmm coord to ali coord from ali coord to env coord from env coord to acc

1 7 3.7e-13 2e-09 37.8 0.1 7 48 342 388 338 395 0.93

2 7 3.7e-13 2e-09 37.8 0.1 7 48 410 456 406 463 0.93

3 7 3.7e-13 2e-09 37.8 0.1 7 48 478 524 474 531 0.93

4 7 3.7e-13 2e-09 37.8 0.1 7 48 546 592 542 599 0.93

5 7 3.7e-13 2e-09 37.8 0.1 7 48 614 660 610 667 0.93

6 7 3.7e-13 2e-09 37.8 0.1 7 48 682 728 678 735 0.93

7 7 7.2e-17 3.9e-13 49.6 0.0 7 70 750 814 746 818 0.94

#	of	c-Evalue	i-Evalue	score	bias	hmm coord from	hmm coord to	ali coord from	ali coord to	env coord from	env coord to	acc
1	7	3.7e-13	2e-09	37.8	0.1	7	48	342	388	338	395	0.93
2	7	3.7e-13	2e-09	37.8	0.1	7	48	410	456	406	463	0.93
3	7	3.7e-13	2e-09	37.8	0.1	7	48	478	524	474	531	0.93
4	7	3.7e-13	2e-09	37.8	0.1	7	48	546	592	542	599	0.93
5	7	3.7e-13	2e-09	37.8	0.1	7	48	614	660	610	667	0.93
6	7	3.7e-13	2e-09	37.8	0.1	7	48	682	728	678	735	0.93
7	7	7.2e-17	3.9e-13	49.6	0.0	7	70	750	814	746	818	0.94

Sequence Information

Coding Sequence: ATGGCGGTTGGTGATAAGACTCCAAGCGAAGAGAGTAAAGTTGGCGGCGATGAATTGGAGACGGAGCCCACTGACGTCGCGGCGGCCTCGGAGATCCCCTCGGAGACTGCGACGCCCGAGCCCCAACAATTCTCTGCGCCTGTGGAAGAACCACCACCGAGTACTTCCGAGAAAGATCTTCCAGAAACAATAGCAGCGATCATAGAAGAACTAGGCAAAGATGATACAATAGACCAAAGTGACACCATGGGAAACAATGATGACTTGCAAAACGACATTGAAATGAGAAACGTGATTGACATTAAGAATGACCCTGATGTTAAAGACGAAGACATATACAATGACGTCAAACGAGGCAATGAGCTActgaaaatgaaacaaaatgcGAAAAAAGCTGCAGAGGTGGACTCTGAAGTGAAGAAATTGGAAGATGAGGCTGCCCCTCCAGTGGAAGCGGCGAAAGGCGTGAAGCGCAGAGCATCCGCTGCTTTCAGTGACGATGGGATGGAGGAGTTCAAAGGTTTTGAGACTTGTGAGTCAAGCGGCCTGGCTGACTACAGTCGCATTGTTGACGAGGTGGAGAGGAGAGTTAAGCGCAGGCCCTCTGAGTGCAGTGAGCCTGAGGATGGGTTCAAAGGTTTCGACCTGAACCAACAGAGCAACTTGACTGGGTACTGTCAGGTCTTAGAGCGCTTGGAAGCGGAGGTGTCAGCGGCCGTGAAGACTTACAAGCCTCTAAAGACGGTGATGGCCGCGCCCACGCCCCGGGCTCGCAAGCGAGCGCGGCAGGACACAGGTGGGTGCAAATGGTCCGAACACCTCGAGGAAGAGGTCTCCGCTGCAGTGCAGAGCTTCCAGGATGAAGGCCAGCCGGCCCCCAGGCCGCGCCAACCCACCGACGGCTCGAGACCATCCTCAGCTTTATCATCGAGATCTGACGACATGGCGATATCCACGGATGCGTCGTCTTCGCCGGCGACCCGTGGCGGGCGCCGCGCCACCGCGGAGATGTCGTCCCCGCTGCTGCGCGTGCCGCTCGAGCGCGGCTGGAAGCGCGAGCTGGTGTACCGCGCGGCCGGCGCCACGGCCGACCAGCCCAACCGACGCAGCGCGGACATCTACTACTACACGCCGCAGGGCAAGAAACTGCGCTCCACCCGCGAGGCGTCGTCTTCGCCGGCGACCCGTGGCGGGCGCCGCGCCACCGCGGAGATGTCGTCCCCGCTGCTGCGCGTGCCGCTCGAGCGCGGCTGGAAGCGCGAGCTGGTGTACCGCGCGGCCGGCGCCACGGCCGACCAGCCCAACCGACGCAGCGCGGACATCTACTACTACACGCCGCAGGGCAAGAAACTGCGCTCCACCCGCGAGGCGTCGTCTTCGCCGGCGACCCGTGGCGGGCGCCGCGCCACCGCGGAGATGTCGTCCCCGCTGCTGCGCGTGCCGCTCGAGCGCGGCTGGAAGCGCGAGCTGGTGTACCGCGCGGCCGGCGCCACGGCCGACCAGCCCAACCGACGCAGCGCGGACATCTACTACTACACGCCGCAGGGCAAGAAACTGCGCTCCACCCGCGAGGCGTCGTCTTCGCCGGCGACCCGTGGCGGGCGCCGCGCCACCGCGGAGATGTCGTCCCCGCTGCTGCGCGTGCCGCTCGAGCGCGGCTGGAAGCGCGAGCTGGTGTACCGCGCGGCCGGCGCCACGGCCGACCAGCCCAACCGACGCAGCGCGGACATCTACTACTACACGCCGCAGGGCAAGAAACTGCGCTCCACCCGCGAGGCGTCGTCTTCGCCGGCGACCCGTGGCGGGCGCCGCGCCACCGCGGAGATGTCGTCCCCGCTGCTGCGCGTGCCGCTCGAGCGCGGCTGGAAGCGCGAGCTGGTGTACCGCGCGGCCGGCGCCACGGCCGACCAGCCCAACCGACGCAGCGCGGACATCTACTACTACACGCCGCAGGGCAAGAAACTGCGCTCCACCCGCGAGGCGTCGTCTTCGCCGGCGACCCGTGGCGGGCGCCGCGCCACCGCGGAGATGTCGTCCCCGCTGCTGCGCGTGCCGCTCGAGCGCGGCTGGAAGCGCGAGCTGGTGTACCGCGCGGCCGGCGCCACGGCCGACCAGCCCAACCGACGCAGCGCGGACATCTACTACTACACGCCGCAGGGCAAGAAACTGCGCTCCACCCGCGAGGCGTCGTCTTCGCCGGCGACCCGTGGCGGGCGCCGCGCCACCGCGGAGATGTCGTCCCCGCTGCTGCGCGTGCCGCTCGAGCGCGGCTGGAAGCGCGAGCTGGTGTACCGCGCGGCCGGCGCCACGGCCGACCAGCCCAACCGACGCAGCGCGGACATCTACTACTACACGCCGCAGGGCAAGAAACTGCGCTCCACCCGCGAGGTCTCAGAACACTTGTCCGGAACTGGTCTGACGATAGACAACTTCTCATTCTTCAAAGAGCCGCTAGGAATCGATGATCCTGATAAGGAAATCATACGGGATGCGAAAGTGAATCGACGCGTGGAGTCCCCGGTGCCGGTAGCGCCGCCGCTCACGGTGGAGGGCAAGCGAACGCCGAAGCCCAAACCGCCAAAAGGCGCCAGCCCCGAGCCCAGCACTCCCAAGTCTCCGCCGGCTAAAATTAAAGTAAAGTCTATGGGCTCCCGTCTAAGCAGCAACGGGGCAACACCAAAGAGCGGGAAAAAACAACCACAACCGCAGTCCGCAGCGCAACCGCAGTCCGCGCTGACGCAACCGCAGTCCGCAACCACGCCGGCCGACAACAACAACACAGCCGCGTGGAAGAAACCCAGGGGCccgccgccgctgcagccgcgccccccgcccgccgcgccgcccgcgcacgagccgcacgcgcacgctgcgcacgccgcgcacgccgccgctcAGCACCGACAGCTGGGTCGCCAAGTGCAGCAGCCGTGCTCCATGAcgtgcgggcgcggcgtgccCTCGCTCGCGTGCGCGACGTGCCTCTGCCTCTACCACCCGCCGTGCGTGGGCTTCGTGGTCGTCGCGCCGCCGGACAGGTTCATATGCAAGaaCTGTCGCAAATCGTCGTCCCCACCTCTCGAACCGCCCCCTCTCATCCACAAATCGGGGGTGACAACCACCGCGCACCACCCTCAACTGCCAAGTATACCCAGCATGTCAGCAAACGTCGCCAATGTGTCGGCCAATGTACCCGCCAACGCATCTTCCAACACACCGCCATCAACAGCTAGACGCCTGCCCGTACCTGTGCCCGTGCCCGCTAAAGTGCCGAAAAGTGATAAACGGGTCCTTTTGAGAATGAAGGTGGCAGGCGGCGGTCCAGACGGCGAGCGAGTGTGGGCGGTCGCTAAGCCAACACCGACAGCTCCCGTCGCCtcggcgcccgcgccgccgcccgtcCCAACCCCCCCTGCCGCCCCGCCCCCTCCGGCACCTGTCCTAGTTCCCGCGCCGCCGGTTGCCGCCCCTCCTGTTCTGGCGCCCGCACCTATACCCGTGCCAGTCCCGGTGCCAGTGTGCCGACCGACCCTGCCACAGTCGCTGGCGATACTCAACGGCAGGAAGTTCATTGTGGTCTCGAGAGCACTGCATCGCGAAGCCGGCAAGACGCTCCGGAGTCGTATCGCGAACGGCGCCGCGtccccgcccgcgcccgcgcagtcgccgcgccgccgcggccgCTCCAGGGTCGACGACACGGACCACTTCACGGCGTTCCACAGCAGGGCGCAGGAGAACAACTACAACATCGCCGTGCAGATCTTCCAGTACCTGGGCATGCGCGACCTAGCACGTGCGGCGCGCGTGTGCAAGCTGTGGCAGCAGCTCGCCGCCACGCCTGCGCTCTGGAGGCACGTGCGCATGAAGAACTCGCACGTGAGCGACTGGGCGGGGCTGTGCGGCGCGCTCAAGCGCCACGGCACGCGCTGGCTGGACCTGCGCAAGATGCTGCTGCCGCCCAACGACACGCTGTTCTGGGACCACTTCGCGCAGCACATCGGCTCCGTCGACACGCTCGAAAGGTTAGAGCTGTGCCGCTGCCCGGCGCGCGCGGTGCAGGCGGCGTGCGAGAGGCTGcccggcctgcgcgcgctggccgcgcccgcCATACGCGACGCGCGCCTCGACCCCTCCCCGCTCGCCGGCCTGCCGCGCCTGGAGCTGCTGCGGCTCAAGAGCTGTGCCGCTGCCCGGCGCGCGCGGTGCAGGCGGCGTGCGAGAGGCTGcccggcctgcgcgcgctggccgcgcccgcCATACGCGACGCGCGCCTCGACCCCTCCCCGCTCGCCGGCCTGCCGCGCCTGGAGCTGCTGCGGCTCAAGGTCAGTGCTGTCCAGTGTAGAGCTGTGCCGCTGCCCGGCGCGCGCGGTGCAGGCGGCGTGCGAGAGGCTGcccggcctgcgcgcgctggccgcgcccgcCATACGCGACGCGCGCCTCGACCCCTCCCCGCTCGCCGGCCTGCCGCGCCTGGAGCTGCTGCGGCTCAAGGTCAGTGCTGTCCAGTGTAGAGCTGTGCCGCTGCCCGGCGCGCGCGGTGCAGGCGGCGTGCGAGAGGCTGcccggcctgcgcgcgctggccgcgcccgcCATACGCGACGCGCGCCTCGACCCCTCCCCGCTCGCCGGCCTGCCGCGCCTGGAGCTGCTGCGGCTCAAGAGCTGTGCCGCTGCCCGGCGCGCGCGGTGCAGGCGGCGTGCGAGAGGCTGcccggcctgcgcgcgctggccgcgcccgcCATACGCGACGCGCGCCTCGACCCCTCCCCGCTCGCCGGCCTGCCGCGCCTGGAGCTGCTGCGGCTCAAGGCGGCGTGCGAGAGGCTGcccggcctgcgcgcgctggccgcgcccgcCATACGCGACGCGCGCCTCGACCCCTCCCCGCTCGCCGGCCTGCCGCGCCTGGAGCTGCTGCGGCTCAAGAGCTGTGCCGCTGCCCGGCGCGCGCGGTGCAGGCGGCGTGCGAGAGGCTGcccggcctgcgcgcgctggccgcgcccgcCATACGCGACGCGCGCCTCGACCCCTCCCCGCTCGCCGGCCTGCCGCGCCTGGAGCTGCTGCGGCTCAAGGTCAGTGCTGTCCAGTGTAGAGCTGTGCCGCTGCCCGGCGCGCGCGGTGCAGGCGGCGTGCGAGAGGCTGcccggcctgcgcgcgctggccgcgcccgcCATACGCGACGCGCGCCTCGACCCCTCCCCGCTCGCCGGCCTGCCGCGCCTGGAGCTGCTGCGGCTCAAGGTCAGTGCTGTCCAGTGTAGAGCTGTGCCGCTGCCCGGCGCGCGCGGTGCAGGCGGCGTGCGAGAGGCTGcccggcctgcgcgcgctggccgcgcccgcCATACGCGACGCGCGCCTCGACCCCTCCCCGCTCGCCGGCCTGCCGCGCCTGGAGCTGCTGCGGCTCAAGAGCTGTGCCGCTGCCCGGCGCGCGCGGTGCAGGCGGCGTGCGAGAGGCTGcccggcctgcgcgcgctggccgcgcccgcCATACGCGACGCGCGCCTCGACCCCTCCCCGCTCGCCGGCCTGCCGCGCCTGGAGCTGCTGCGGCTCAAGGTCAGTGCTGTCCAGTGTAGAGCTGTGCCGCTGCCCGGCGCGCGCGGTGCAGGCGGCGTGCGAGAGGCTGCCCGGCCTGCGCCCGCCATACGCGACGCGCGCCTCGACCCCTCCCCGCTCGCCGGCCTGCCGCGCCTGGAGCTGCTGCGGCTCAAGGTCAGTGCTGTCCAGTGTAGAGCTGTGCCGCTGCCCGGCGCGCGCGGTGCAGGCGGCGTGCGAGAGGCTGcccggcctgcgcgcgctggccgcgcccgcCATACGCGACGCGCGCCTCGACCCCTCCCCGCTCGCCGGCCTGCCGCGCCTGGAGCTGCTGCGGCTCAAGAGCTGTGCCGCTGCCCGGCGCGCGCGGTGCAGGCGGCGTGCGAGAGGCTGcccggcctgcgcgcgctggccgcgcccgcCATACGCGACGCGCGCCTCGACCCCTCCCCGCTCGCCGGCCTGCCGCGCCTGGAGCTGCTGCGGCTCAAGAGCTGTGCCGCTGCCCGGCGCGCGCGGTGCAGGCGGCGTGCGAGAGGCTGcccggcctgcgcgcgctggccgcgcccgcCATACGCGACGCGCGCCTCGACCCCTCCCCGCTCGCCGGCCTGCCGCGCCTGGAGCTGCTGCGGCTCAAGGTCAGTGCTGTCCAGTGTAGAGCTGTGCCGCTGCCCGGCGCGCGCGGTGCAGGCGGCGTGCGAGAGGCTGcccggcctgcgcgcgctggccgcgcccgcCATACGCGACGCGCGCCTCGACCCCTCCCCGCTCGCCGGCCTGCCGCGCCTGGAGCTGCTGCGGCTCAAGGTCAGTGCTGTCCACTGTAGAGCTGTGCCGCTGCCCGGCGCGCGCGGTGCAGGCGGCGTGCGAGAGGCTGcccggcctgcgcgcgctggccgcgcccgcCATACGCGACGCGCGCCTCGACCCCTCCCCGCTCGCCGGCCTGCCGCGCCTGGAGCTGCTGCGGCTCAAGAGCTGTGCCGCTGCCCGGCGCGCGCGGTGCAGGCGGCGTGCGAGAGGCTGcccggcctgcgcgcgctggccgcgcccgcCATACGCGACGCGCGCCTCGACCCCTCCCCGCTCGCCGGCCTGCCGCGCCTGGAGCTGCTGCGGCTCAAGAGCCTCGCGGGGCTATCCCTCACGCGGGACCTGCGCCCCCTGGCCGAGCTGACGCGCCTGCAGCACCTGTCGCTGACGTCCATCAAGGAGCTGGGCTGGTGCGCGTGTGAGGTGGTCGGTCAGCTGGAGAACCTCGAGTCTCTAGAGCTGGGCGAGTGCTCCTTCGGCGGCTCCTTCGCGACCGCGTTAGGCAAGCTGGTGAAGTTGCGGCGGCTGCGGCTGGAGCGCGGCGTGGCGCACTGCGCGGCGCCGGCGTTactgcgcgcgctcgccgcgctgcccaAGCTCACGAGGCTCGAGCTGGTCAACTTTGACGTCAAGGTAGGCTTCGATGACGCGCTCGCGGAGTGCAAGAATATCCAGAGGCTGCTCATCATACCCACCTACGTGTCGCAGTCCGCCACCACCAACAAACAGGTGCTAAGCGGCGTGCTGAGACTAAAAGAGACGCTCACGCACCTGATGTGGGGCGTCACCATCGAGCTGCTGCGAGTCACGGAGCTGTTCATCGACCAATGCGAGGCGGGCGAGGGGGACAGCAAGAGGCGCGACGTGGGCGAGTGCATCCCCGTGCTGAAGCCGGTGCCGGGCTGCAGGCTGCCCGACGACCACCGCACCGTCGCCGGCCCGCCGCAGGTGGAGATCCTGCCGATCCCGACGCTGCAGCGCCTGCTGTCGGCGCAGCTGCCCAACACCAAGCTGAAGCTGCTGCGCATCCCGTTCCACGCCACGTGGCGCCAGTCGCTCGCCGACTTCCAGTAG
Protein Sequence: MAVGDKTPSEESKVGGDELETEPTDVAAASEIPSETATPEPQQFSAPVEEPPPSTSEKDLPETIAAIIEELGKDDTIDQSDTMGNNDDLQNDIEMRNVIDIKNDPDVKDEDIYNDVKRGNELLKMKQNAKKAAEVDSEVKKLEDEAAPPVEAAKGVKRRASAAFSDDGMEEFKGFETCESSGLADYSRIVDEVERRVKRRPSECSEPEDGFKGFDLNQQSNLTGYCQVLERLEAEVSAAVKTYKPLKTVMAAPTPRARKRARQDTGGCKWSEHLEEEVSAAVQSFQDEGQPAPRPRQPTDGSRPSSALSSRSDDMAISTDASSSPATRGGRRATAEMSSPLLRVPLERGWKRELVYRAAGATADQPNRRSADIYYYTPQGKKLRSTREASSSPATRGGRRATAEMSSPLLRVPLERGWKRELVYRAAGATADQPNRRSADIYYYTPQGKKLRSTREASSSPATRGGRRATAEMSSPLLRVPLERGWKRELVYRAAGATADQPNRRSADIYYYTPQGKKLRSTREASSSPATRGGRRATAEMSSPLLRVPLERGWKRELVYRAAGATADQPNRRSADIYYYTPQGKKLRSTREASSSPATRGGRRATAEMSSPLLRVPLERGWKRELVYRAAGATADQPNRRSADIYYYTPQGKKLRSTREASSSPATRGGRRATAEMSSPLLRVPLERGWKRELVYRAAGATADQPNRRSADIYYYTPQGKKLRSTREASSSPATRGGRRATAEMSSPLLRVPLERGWKRELVYRAAGATADQPNRRSADIYYYTPQGKKLRSTREVSEHLSGTGLTIDNFSFFKEPLGIDDPDKEIIRDAKVNRRVESPVPVAPPLTVEGKRTPKPKPPKGASPEPSTPKSPPAKIKVKSMGSRLSSNGATPKSGKKQPQPQSAAQPQSALTQPQSATTPADNNNTAAWKKPRGPPPLQPRPPPAAPPAHEPHAHAAHAAHAAAQHRQLGRQVQQPCSMTCGRGVPSLACATCLCLYHPPCVGFVVVAPPDRFICKNCRKSSSPPLEPPPLIHKSGVTTTAHHPQLPSIPSMSANVANVSANVPANASSNTPPSTARRLPVPVPVPAKVPKSDKRVLLRMKVAGGGPDGERVWAVAKPTPTAPVASAPAPPPVPTPPAAPPPPAPVLVPAPPVAAPPVLAPAPIPVPVPVPVCRPTLPQSLAILNGRKFIVVSRALHREAGKTLRSRIANGAASPPAPAQSPRRRGRSRVDDTDHFTAFHSRAQENNYNIAVQIFQYLGMRDLARAARVCKLWQQLAATPALWRHVRMKNSHVSDWAGLCGALKRHGTRWLDLRKMLLPPNDTLFWDHFAQHIGSVDTLERLELCRCPARAVQAACERLPGLRALAAPAIRDARLDPSPLAGLPRLELLRLKSCAAARRARCRRRARGCPACARWPRPPYATRASTPPRSPACRAWSCCGSRSVLSSVELCRCPARAVQAACERLPGLRALAAPAIRDARLDPSPLAGLPRLELLRLKVSAVQCRAVPLPGARGAGGVREAARPARAGRARHTRRAPRPLPARRPAAPGAAAAQELCRCPARAVQAACERLPGLRALAAPAIRDARLDPSPLAGLPRLELLRLKAACERLPGLRALAAPAIRDARLDPSPLAGLPRLELLRLKSCAAARRARCRRRARGCPACARWPRPPYATRASTPPRSPACRAWSCCGSRSVLSSVELCRCPARAVQAACERLPGLRALAAPAIRDARLDPSPLAGLPRLELLRLKVSAVQCRAVPLPGARGAGGVREAARPARAGRARHTRRAPRPLPARRPAAPGAAAAQELCRCPARAVQAACERLPGLRALAAPAIRDARLDPSPLAGLPRLELLRLKVSAVQCRAVPLPGARGAGGVREAARPAPAIRDARLDPSPLAGLPRLELLRLKVSAVQCRAVPLPGARGAGGVREAARPARAGRARHTRRAPRPLPARRPAAPGAAAAQELCRCPARAVQAACERLPGLRALAAPAIRDARLDPSPLAGLPRLELLRLKSCAAARRARCRRRARGCPACARWPRPPYATRASTPPRSPACRAWSCCGSRSVLSSVELCRCPARAVQAACERLPGLRALAAPAIRDARLDPSPLAGLPRLELLRLKVSAVHCRAVPLPGARGAGGVREAARPARAGRARHTRRAPRPLPARRPAAPGAAAAQELCRCPARAVQAACERLPGLRALAAPAIRDARLDPSPLAGLPRLELLRLKSLAGLSLTRDLRPLAELTRLQHLSLTSIKELGWCACEVVGQLENLESLELGECSFGGSFATALGKLVKLRRLRLERGVAHCAAPALLRALAALPKLTRLELVNFDVKVGFDDALAECKNIQRLLIIPTYVSQSATTNKQVLSGVLRLKETLTHLMWGVTIELLRVTELFIDQCEAGEGDSKRRDVGECIPVLKPVPGCRLPDDHRTVAGPPQVEILPIPTLQRLLSAQLPNTKLKLLRIPFHATWRQSLADFQ

Similar Transcription Factors

Sequence clustering based on sequence similarity using MMseqs2

100% Identity: -
90% Identity: -
80% Identity: -