Basic Information

Insect: Cochliomyia hominivorax
Gene Symbol: L
Assembly: GCA_004302925.1
Location: PYHX01003216.1:2616332-2627627[+]

Transcription Factor Domain

TF Family: zf-C2H2
Domain: zf-C2H2 domain
PFAM: PF00096
TF Group: Zinc-Coordinating Group
Description: The C2H2 zinc finger is the classical zinc finger domain. The two conserved cysteines and histidines co-ordinate a zinc ion. The following pattern describes the zinc finger. #-X-C-X(1-5)-C-X3-#-X5-#-X2-H-X(3-6)-[H/C] Where X can be any amino acid, and numbers in brackets indicate the number of residues. The positions marked # are those that are important for the stable fold of the zinc finger. The final position can be either his or cys. The C2H2 zinc finger is composed of two short beta strands followed by an alpha helix. The amino terminal part of the helix binds the major groove in DNA binding zinc fingers. The accepted consensus binding sequence for Sp1 is usually defined by the asymmetric hexanucleotide core GGGCGG but this sequence does not include, among others, the GAG (=CTC) repeat that constitutes a high-affinity site for Sp1 binding to the wt1 promoter [1].
Hmmscan Out: # of c-Evalue i-Evalue score bias hmm coord from hmm coord to ali coord from ali coord to env coord from env coord to acc

1 18 7.4e-06 0.00038 20.7 1.7 1 23 263 285 263 285 0.98

2 18 0.59 31 5.2 5.7 1 23 291 313 291 313 0.98

3 18 3.2e-07 1.7e-05 25.0 3.1 1 23 319 341 319 341 0.99

4 18 1.5e-05 0.00077 19.7 0.3 1 23 347 369 347 369 0.98

5 18 3.6 1.9e+02 2.8 0.8 2 23 434 457 433 457 0.85

6 18 0.0033 0.17 12.3 0.3 2 23 484 506 483 506 0.96

7 18 0.039 2 9.0 0.7 1 23 607 629 607 629 0.97

8 18 0.43 22 5.7 2.0 2 23 637 658 636 658 0.95

9 18 0.00054 0.028 14.8 0.6 1 23 666 690 666 690 0.94

10 18 1.5 80 3.9 0.0 2 19 696 713 695 715 0.92

11 18 0.0019 0.1 13.1 2.9 1 23 787 809 787 810 0.96

12 18 4.2 2.2e+02 2.6 0.9 1 23 977 1001 977 1001 0.89

13 18 0.0011 0.058 13.8 4.8 2 23 1010 1032 1009 1032 0.97

14 18 0.16 8.4 7.0 0.1 1 23 1038 1060 1038 1060 0.92

15 18 0.014 0.72 10.4 0.4 2 23 1068 1089 1067 1089 0.96

16 18 1 54 4.5 0.5 2 23 1179 1200 1179 1200 0.94

17 18 0.0023 0.12 12.8 0.0 1 23 1210 1232 1210 1232 0.97

18 18 0.014 0.72 10.4 0.7 1 23 1239 1261 1239 1261 0.95

#	of	c-Evalue	i-Evalue	score	bias	hmm coord from	hmm coord to	ali coord from	ali coord to	env coord from	env coord to	acc
1	18	7.4e-06	0.00038	20.7	1.7	1	23	263	285	263	285	0.98
2	18	0.59	31	5.2	5.7	1	23	291	313	291	313	0.98
3	18	3.2e-07	1.7e-05	25.0	3.1	1	23	319	341	319	341	0.99
4	18	1.5e-05	0.00077	19.7	0.3	1	23	347	369	347	369	0.98
5	18	3.6	1.9e+02	2.8	0.8	2	23	434	457	433	457	0.85
6	18	0.0033	0.17	12.3	0.3	2	23	484	506	483	506	0.96
7	18	0.039	2	9.0	0.7	1	23	607	629	607	629	0.97
8	18	0.43	22	5.7	2.0	2	23	637	658	636	658	0.95
9	18	0.00054	0.028	14.8	0.6	1	23	666	690	666	690	0.94
10	18	1.5	80	3.9	0.0	2	19	696	713	695	715	0.92
11	18	0.0019	0.1	13.1	2.9	1	23	787	809	787	810	0.96
12	18	4.2	2.2e+02	2.6	0.9	1	23	977	1001	977	1001	0.89
13	18	0.0011	0.058	13.8	4.8	2	23	1010	1032	1009	1032	0.97
14	18	0.16	8.4	7.0	0.1	1	23	1038	1060	1038	1060	0.92
15	18	0.014	0.72	10.4	0.4	2	23	1068	1089	1067	1089	0.96
16	18	1	54	4.5	0.5	2	23	1179	1200	1179	1200	0.94
17	18	0.0023	0.12	12.8	0.0	1	23	1210	1232	1210	1232	0.97
18	18	0.014	0.72	10.4	0.7	1	23	1239	1261	1239	1261	0.95

Sequence Information

Coding Sequence: ATGATggctttaaaaatgttataccgTGGACCCAGTTCaagattagaaaatttaattgaaaaaattcaagCCACCAAAGAGATTGTTAATGCCgacATGTACTCGACGCATACATCTTCAAGTTATTCACCTTCAATATCAGATGGTACCATAACACCAAATTCtttacatcatcatcatcaccatcagcATTTAAATGTGCCACCACCAACACAAACAACACAATTACCATTTTCCAATTCCTCGGCTGGTTATGAAGAAGACACAACATCTTCGTTGGCTCTACAGACACAACGTCTGCAACGACAAAAAACCAATGGCTCTTTGGATGGCGCTGACTATGAAGAGAACGCTAATGACAATGACAATGACAATAACAACGACGATAACGACAACAACAGCGAAAGGATTCACAAAAATGATACAAAATTATGTGAAGACAATGACACAATTGTTGCAGACAATAAGACAACAACCGAAAAAATTCACGAAAGTGGCGAAgaacatcatcatcagcagcatcaTCATCAACTTAAACGTCATGGCCGTCATCATCGTTATGCTGAACATGCCTTAAGAATTCCTTCAAAATTACGTAAAATCGATAGGGATTCAACGGTGGGTAATGGTACTGGTGTCGGCGGTATTGCTACTACATCTACTGTTGCTGCCGCATcaagtggtggtggtggtgctgGTAGTGTAGCAACAAATGCAGTCAAGTTTGATAAGTTGACAGGAGATGGCATTAAAAGTGGTAACAATGCTTCAAGTGCCGACGGATCCTATCAATGTCAATTCTGTGATAAATCATTTCCGCGTCTTGGTTATTTGAAAAAACACGAACAGaGTCATGCTGAACATTTACCTTTTAAATGTGAATATTGTGCTCGTCTCTTCAAGCACAAACGTTCTCGTGATCGTCATACTAAACTGCATACAGGTGATCGTCGCTATCGTTGTCCTCATTGCGAAGCAGCTTTTTCAAGAAGTGATCATTTAAAAATCCATATGAAAACTCATGATAACCAAAAACCTTTTCAATGTACCATTTGTAATCGTGGTTATAATACTGCTGCTGCTCTCACTTCTCACatgcaaaatcataaaaaacagGCTGCACTTTTGGCTGCTGGAGGCAACCCACAAGCTTTAAACTACAGCCCCCGTTCTACGGGTTCAGCTTCTAGTAATGGCAGTTTACAAAAGAGACGTTATGGCCTTGCTGGAGCATCTGAACAAAGTCCTAACCGTCTTGATTATCCAAAACGCGGTCGTTCTTCCTCAACGAATATGCTCAAGTGTACATTTTGTTCAAAGTCCGATTTTACTGCAGTGGAACAGCTAAACAATCATTTGCAGACACAACATGAAAAGGAATTGGCTCATTCCATGACACCTCCCACCACTAATAGTCATCCACCAATGGATAATCCTACTTTTCAATTGTCGTGTGAATATTGTACCATGAAATTTCCTAACATTGCTGCCATGTTTCAACACATGCGTTCATCCCATTTGGATCGTTTAACTAGCCCCAATTCCTATTTCGAACACTTTAATCGTCTAGCTGCCTCGGGTACATTTAGTCCCCGCTTGCTAACAGGACCTCCTCTACGAAATACTCTCAGCGTGGAGGACAATTCTATTAAAGTAGAACATAATATATCAAGTCCAAAGTCCGTAGAAGCCATTACAAGGCAAAGTGAAGATGAACCTACGGATCTCAGCCAAAATAATCGCAGATCTATGACACCTACAAATACTCCTCAAAATTCTCcccaagaaaattttcaacctACCGAAAAACCGGGTTTATTCTTTTGTAATCAATGTAATGCTGGTTTACCCGACTTTGAATCATTCCGCAATCATTTAAAAACACATATTGCACAAGGCCTCAATTTGGTGTGTCATCATTGTGGTCTTCTTCTTAGGGAACATGCAGAATATGAGAGACATGTTATATCACATTTTCTCATAACAAATTCAGAATACAATTGTTCGGGAAACTGCCAAAAGTCTTTTGGAAAATCAGAGGAATTACAAAAACATCTTATGGATCAACATGCCATAACGATGATTAAATGTGGACTCTGCAGTGAAATGTTTGAATCGAAAGTTGCCATACAGGTGCATTTTGCCTGTACTCACTCGGCTGAAACCAAGATCCTTAGATGTTCAGCCTGCATGGATGTATTTAGAACAGAAACTGATTTCAACTTACACGTTAAATCACGTCATCAAGCTGTAAATAACAATCCTGCTCCCGTAAACACTTTGCAATGTATGTTTTGCCGTACGGTGTGTTCCTCAGACTTGGAAATGCAATTCCATTTAGCTGCACATGCAAGGCAATTTCGTTGTCCTTCTTGCCCAGAAACTTTCCATGTAGAATTTTTACTCGATCGTCATATGCAAACACATCATGGTGGTTTGGAACGACCACCACCACCGCCTCCGCCACAAGCTTTGACAGAGGAACACACATCACCAATAGCTAATCCAAATCCCATATCTCCTATGAATTCTCTGTATGTCAATGCTCTATTTGGCAAGTCACCTTTAATGCCACTAGCagcacaaaataataacaacagcattTTGGATTACAACATGGCTTTTGCTTCTCATCTTAATAAGGGCCTATTTCCCAATACCACGACAAACAAATTCTACAATCCTCTGCAAATCGACACAAATGCCATGAAACACTCAGCTCTCATGTACGGTTTATCGCAAAGATATTTTGATACAAATCGCACAGTTATGGAAAtgtaccaacaacaacaacagcagcaacaacaacaccaccCGGAAAATAAAACTCCAGGAAACTATTTCATAAGTCCCAAACAACCAACTGCACCAACTCACGACATACATCACCGAACTGAGGTAACACCTTCGCCAATCAACAATACTGGTTTTAGTTGTGGAATATGCGAACGTAACGATTTTCGTACAGAATCGGAAGTTCATTCACATCGTAAGATTGTGCATAATTTAAAAACGGGAGTTAGTTTAAAGTGTGCTTATTGTTCGGGTAACTTTAAGTCACGTAGTGAATTGGAGCATCATATGAAAACTTGTCATAATTCCACCGGCAAACACAAGTGTTTAATATGTGATGAAATCTTTCCTTCGCCTGCCATATTGGCTGAACATAAACTGCAACATTCCAAGGTGGGACAATCAGGAAAATGTTCTCATTGCTCAAAGGCTTTAGCAGATGTTAGTGCATTCAAAGCTCATCTATCCGAACACAATACAGAGGGACAAATGCCGGTACAATGTATATGTTGTCGCCAATCATTACACTCGGAATTTGAGATTGGACTACATGCAAAatTCCATGTTAAAAATTCCATCGTTCAAGAAAATGTTTGTGCTCTTTGCTTGGAGCCCATTACCAATTCTCCCACTGAAGCCAAAGTATGTGAGAAATGTTGCCGTAAACATAatctaaataacaaatttaagcaACGCGATCACTATGATCGTCCTGCTGAACTAAGGCAATATATTGAGAATCGTTGTAATCTTTGTAAAATGATCTTACCACATGCCCAAAAACTACAAGAGCACTTGGTGGAACACACTTTTGCTGGTTGCGAAGATCGTGGTTTCAATTGTTACATCTGTTCGGCAGTGTTTACGGCACCCAGTGGTCTACTTAACCATATGCTGGAACATGGCATCAACTCAAAACCGTACGATTGCAATCTATGTCCCGAAAAATTCTATTTCCGTGCTGAATTAGATCATCATCTTATCGATCATGATCTCAGAGAATCACCGGCGGCTGTTAAAAATGAACAAGAGCATTTGgcaaataaagaagaaaatcttAACAATATGAAATCGGAGAAACCTCAAAGTGGTTTAAATGAAGTAAAACAAGAAGTTATAGAAACTGATCACAATTCCAATATTGCCGAAGAAGACGAATACATAGAGGTGGAaaagataaatgaaaataataacaataacaacaacagcaatccATTAAATACTGCATCAGCGGATAAAACTAAAGACACTAAAGAGAAATCCACTGaatga
Protein Sequence: MMALKMLYRGPSSRLENLIEKIQATKEIVNADMYSTHTSSSYSPSISDGTITPNSLHHHHHHQHLNVPPPTQTTQLPFSNSSAGYEEDTTSSLALQTQRLQRQKTNGSLDGADYEENANDNDNDNNNDDNDNNSERIHKNDTKLCEDNDTIVADNKTTTEKIHESGEEHHHQQHHHQLKRHGRHHRYAEHALRIPSKLRKIDRDSTVGNGTGVGGIATTSTVAAASSGGGGAGSVATNAVKFDKLTGDGIKSGNNASSADGSYQCQFCDKSFPRLGYLKKHEQSHAEHLPFKCEYCARLFKHKRSRDRHTKLHTGDRRYRCPHCEAAFSRSDHLKIHMKTHDNQKPFQCTICNRGYNTAAALTSHMQNHKKQAALLAAGGNPQALNYSPRSTGSASSNGSLQKRRYGLAGASEQSPNRLDYPKRGRSSSTNMLKCTFCSKSDFTAVEQLNNHLQTQHEKELAHSMTPPTTNSHPPMDNPTFQLSCEYCTMKFPNIAAMFQHMRSSHLDRLTSPNSYFEHFNRLAASGTFSPRLLTGPPLRNTLSVEDNSIKVEHNISSPKSVEAITRQSEDEPTDLSQNNRRSMTPTNTPQNSPQENFQPTEKPGLFFCNQCNAGLPDFESFRNHLKTHIAQGLNLVCHHCGLLLREHAEYERHVISHFLITNSEYNCSGNCQKSFGKSEELQKHLMDQHAITMIKCGLCSEMFESKVAIQVHFACTHSAETKILRCSACMDVFRTETDFNLHVKSRHQAVNNNPAPVNTLQCMFCRTVCSSDLEMQFHLAAHARQFRCPSCPETFHVEFLLDRHMQTHHGGLERPPPPPPPQALTEEHTSPIANPNPISPMNSLYVNALFGKSPLMPLAAQNNNNSILDYNMAFASHLNKGLFPNTTTNKFYNPLQIDTNAMKHSALMYGLSQRYFDTNRTVMEMYQQQQQQQQQHHPENKTPGNYFISPKQPTAPTHDIHHRTEVTPSPINNTGFSCGICERNDFRTESEVHSHRKIVHNLKTGVSLKCAYCSGNFKSRSELEHHMKTCHNSTGKHKCLICDEIFPSPAILAEHKLQHSKVGQSGKCSHCSKALADVSAFKAHLSEHNTEGQMPVQCICCRQSLHSEFEIGLHAKFHVKNSIVQENVCALCLEPITNSPTEAKVCEKCCRKHNLNNKFKQRDHYDRPAELRQYIENRCNLCKMILPHAQKLQEHLVEHTFAGCEDRGFNCYICSAVFTAPSGLLNHMLEHGINSKPYDCNLCPEKFYFRAELDHHLIDHDLRESPAAVKNEQEHLANKEENLNNMKSEKPQSGLNEVKQEVIETDHNSNIAEEDEYIEVEKINENNNNNNNSNPLNTASADKTKDTKEKSTE

Similar Transcription Factors

Sequence clustering based on sequence similarity using MMseqs2

100% Identity: iTF_01237143;
90% Identity: -
80% Identity: -