Chom008322.1


Basic Information
Transcription Factor Domain
Sequence Information
Similer Transcription Factors

Basic Information

Insect
Cochliomyia hominivorax
Gene Symbol
-
Assembly
GCA_004302925.1
Location
PYHX01003216.1:2680048-2684173[+]

Transcription Factor Domain

TF Family
zf-C2H2
Domain
zf-C2H2 domain
PFAM
PF00096
TF Group
Zinc-Coordinating Group
Description
The C2H2 zinc finger is the classical zinc finger domain. The two conserved cysteines and histidines co-ordinate a zinc ion. The following pattern describes the zinc finger. #-X-C-X(1-5)-C-X3-#-X5-#-X2-H-X(3-6)-[H/C] Where X can be any amino acid, and numbers in brackets indicate the number of residues. The positions marked # are those that are important for the stable fold of the zinc finger. The final position can be either his or cys. The C2H2 zinc finger is composed of two short beta strands followed by an alpha helix. The amino terminal part of the helix binds the major groove in DNA binding zinc fingers. The accepted consensus binding sequence for Sp1 is usually defined by the asymmetric hexanucleotide core GGGCGG but this sequence does not include, among others, the GAG (=CTC) repeat that constitutes a high-affinity site for Sp1 binding to the wt1 promoter [1].
Hmmscan Out
# of c-Evalue i-Evalue score bias hmm coord from hmm coord to ali coord from ali coord to env coord from env coord to acc
1 12 0.0041 0.21 12.0 0.4 1 23 364 387 364 387 0.96
2 12 0.00016 0.0084 16.4 2.4 2 23 390 411 389 411 0.97
3 12 0.00012 0.0061 16.9 0.1 1 23 418 440 418 440 0.98
4 12 4.3e-07 2.2e-05 24.6 1.2 1 23 446 468 446 468 0.99
5 12 0.00018 0.0091 16.3 2.5 1 23 475 497 475 497 0.98
6 12 1.9e-06 0.0001 22.5 1.5 1 23 503 525 503 525 0.97
7 12 4.7e-05 0.0025 18.1 0.2 1 23 531 553 531 553 0.97
8 12 2e-05 0.001 19.3 0.8 1 23 559 582 559 582 0.97
9 12 0.0043 0.22 12.0 2.7 1 23 588 611 588 611 0.93
10 12 1.8e-05 0.00092 19.5 1.6 1 23 617 639 617 639 0.98
11 12 0.0001 0.0054 17.0 0.5 1 23 645 667 645 667 0.96
12 12 0.0016 0.082 13.3 0.2 1 22 673 694 673 697 0.92

Sequence Information

Coding Sequence
ATGGAATCTGTTCGCTGTTATTTGTGCGACCATGAATTCGTGGAAGGAGAAGAGCCATGGTTAATGTTTGAGCAGAGATTGCGAGAAGATGGTCAAGTGGAATGTTCCCTGGCCGATTTGTTAGGGtctatattagaaaaaaatttggaagaaaCACTTGCACATTCTACATTATTGTGTGACTCCTGTAATGCAGATGTTTTAGAATACGAGAGTCTTGAGAAGCGTTTCTCTCAGATAagagaaagaattttaaattcatatcgGGAAAATTTGACAATACAAAActtgaataatttaattcatgCAGCTGCCATTAATAATGAAACTTCCTCAAGTCAACAGCGTAATGAAGATTCtaataacaaattgttaaaagGAAATCCGGAAGATACGGGTAATATACAGAACTCTGAATTTGTTGGTATTGCTGACTTGGATTTAGTAGAAGAAGTTCAAGATGAAGAATTAGAAAGTGAAGGGAATGGGAATGAAAATGCTAATGTGTTAGACAGTGATCAAGTTTCTGTTCAGGGTGATGTTGGATATATTGATAATGTCAGTTCACCAATAATAACAGATCAATATGATTTTGCTGCTTTCAATGAACATGTTGCTCAAAATTCATTACCATCAGGAGTTCTGAATTTATCAGATGGTCTTGTCAATTTAGATGTATGTGAAAAGTCTGTCGATGTTCAAGACATACCCCTTGAAGGCCAAgataTAATTATATATGATGTCCACAGTGACCAAATGCAATCTGGCGAATTTATTATTCAGCCAGATAACGATAGCTGCGATTTGAAAACATATGATAGTACTGAAgctgatgatcttaatttcataattaacaAGGATATATTCACAATTGAAGGCAATAATGAGGAATCACAACAATCTGCTTTATCCGAAATTACAGCGAACGAAAACAATGGAAATAACAGTGATATAATTACTTCTGTTTCGCCTAAACCAGTGTGCAGGAAGGATGGTGATTTCTTTATTTGTCTTATTTGTGAAATATCTCAGCAATATGAACGTCATACCCTaatagaacattttcaaaatttccataattgcaaattttacaTGTGTGAACAGTGTCATGAAGGTTTTGAAATACGACAAGATTTAAAAACACATTTGGAAATCGGCCATGTAATAAAGTGCGAATTTTGTGAACGAACATTTACTACAAATCGGCTTTACAAAGTACATAAACGAATgcattttaacaataataaagccTTTGAATGCCCTGTGTGCCAGAAAATGTACGTATCCAAAGCAATTTTAGAGGAACATATGAATACACATACGGGCGTTAGACCCTTTAAATGTAGTGAATGTCCCAAAGATTTTGCTTCCAAATACACGTTGCAAACACATATGAAAATTCATAAGGAAAGGCCGCGTCCATACCAATGTGATCAATGTGATAAACGCTTCTTGAATCAACAAAATCTAAATCAACACAAAAAACTCCATGTTTCGGTAAAAGCTTTCCAATGCGATGTTTGCAATAAAGCTTTTACCACACAGCATAGTTTACAAGTTCATAAAATAGTACATTCGGGTCAGAGACCCTTTATATGTCGTATTTGCGGAAAATCGTTTGCGAGAAGACCCGAAATTAAAGATCATGAACGAATTCACACAGGAGAGAAACCATTTAAATGTGAATATTGTCCTATGGCATTTGCACAACGCACCAATTTGGCCAGTCACAAAAAATCAACGCACTTGAATGAGAAACTACACAAATGCGACATCTGTTTACGATCGTTTAAGCGCAAGCGGTTGTTAGATTATCACAAACAAGCAATTCATACGGGGGAACGGCCCCATAAGTGTCAAATATGCGGTGCAGGTTTTGTCTATCCAGAGCATTACAAAAAACACATGCTTATACACAGTGGCAAGAAACCCTATGCATGTGAAGTATGTGGCAAACAATTTAACAGTCGTGATAATCGTAATGCTCACCGTTTTGTACACAGTGATAAAAAACCTTACGAGTGTATGGAATGTGGAGCAGGTTTTATGAGAAAGCCTCTTCTTCTTACACATATGAAGCAAACGAAACATATAAACGATACCATTATCATAAATCAGCCTCAATTTACTCATCAGCAACCTATTCAAACACCCAACATTCCCACAACATCTTCAACTTCTGTAGATTATGGTAATTTACAGGAGGATGAATCAGAGATAGATGTTGACAATGATTTAAAGCCTCAAGATGTCTCTGATGAAGCATTTGAAAAGGTCTTATTCAAAGCTGATGATTTGTTGGCTGAAACAGTTTCTGTTTCTTCGAATATTAATAATGGCGTGAACGTTGATAGTAACGTAATAACAGTTGTTGCAGATCATTTAATCAAGGATCATTTAGATGATGTTAAATATTTAGGATTTGAAGACTTAGAACGTGATGGTCATCAAACATTAACATGGGTTGATATTAGTGGCGATGACAAagtttga
Protein Sequence
MESVRCYLCDHEFVEGEEPWLMFEQRLREDGQVECSLADLLGSILEKNLEETLAHSTLLCDSCNADVLEYESLEKRFSQIRERILNSYRENLTIQNLNNLIHAAAINNETSSSQQRNEDSNNKLLKGNPEDTGNIQNSEFVGIADLDLVEEVQDEELESEGNGNENANVLDSDQVSVQGDVGYIDNVSSPIITDQYDFAAFNEHVAQNSLPSGVLNLSDGLVNLDVCEKSVDVQDIPLEGQDIIIYDVHSDQMQSGEFIIQPDNDSCDLKTYDSTEADDLNFIINKDIFTIEGNNEESQQSALSEITANENNGNNSDIITSVSPKPVCRKDGDFFICLICEISQQYERHTLIEHFQNFHNCKFYMCEQCHEGFEIRQDLKTHLEIGHVIKCEFCERTFTTNRLYKVHKRMHFNNNKAFECPVCQKMYVSKAILEEHMNTHTGVRPFKCSECPKDFASKYTLQTHMKIHKERPRPYQCDQCDKRFLNQQNLNQHKKLHVSVKAFQCDVCNKAFTTQHSLQVHKIVHSGQRPFICRICGKSFARRPEIKDHERIHTGEKPFKCEYCPMAFAQRTNLASHKKSTHLNEKLHKCDICLRSFKRKRLLDYHKQAIHTGERPHKCQICGAGFVYPEHYKKHMLIHSGKKPYACEVCGKQFNSRDNRNAHRFVHSDKKPYECMECGAGFMRKPLLLTHMKQTKHINDTIIINQPQFTHQQPIQTPNIPTTSSTSVDYGNLQEDESEIDVDNDLKPQDVSDEAFEKVLFKADDLLAETVSVSSNINNGVNVDSNVITVVADHLIKDHLDDVKYLGFEDLERDGHQTLTWVDISGDDKV

Similar Transcription Factors

Sequence clustering based on sequence similarity using MMseqs2

100% Identity
iTF_01259368;
90% Identity
-
80% Identity
-