Chom008753.1
Basic Information
- Insect
- Cochliomyia hominivorax
- Gene Symbol
- Hr39
- Assembly
- GCA_004302925.1
- Location
- PYHX01003114.1:519067-522704[+]
Transcription Factor Domain
- TF Family
- SF-like
- Domain
- zf-C4|SF-like
- PFAM
- AnimalTFDB
- TF Group
- Zinc-Coordinating Group
- Description
- The ligand binding domain of nuclear receptor steroidogenic factor 1 (SF-1): SF-1, a member of the nuclear hormone receptor superfamily, is an essential regulator of endocrine development and function and is considered a master regulator of reproduction. Most nuclear receptors function as homodimer or heterodimers, however SF-1 binds to its target genes as a monomer, recognizing the variations of the DNA sequence motif, T/CCA AGGTCA. SF-1 functions cooperatively with other transcription factors to modulate gene expression. Phospholipids have been determined as potential ligands of SF-1. Like other members of the nuclear receptor (NR) superfamily of ligand-activated transcription factors, SF-1 has a central well conserved DNA binding domain (DBD), a variable N-terminal domain, a flexible hinge and a C-terminal ligand binding domain (LBD). [1, 8, 3, 11, 6, 5, 12, 10, 9, 2, 4, 7]
- Hmmscan Out
-
# of c-Evalue i-Evalue score bias hmm coord from hmm coord to ali coord from ali coord to env coord from env coord to acc 1 3 0.63 5.3e+03 -3.6 10.2 76 178 275 397 233 434 0.53 2 3 2.2e-13 1.9e-09 37.4 18.0 1 154 501 705 501 716 0.77 3 3 3.7e-80 3.1e-76 257.3 0.6 185 408 701 912 697 912 0.95
Sequence Information
- Coding Sequence
- atgtcAACCATTAAAACGGAAAATATAACTGGCGGCGGAGGAGCTGTGGTGACCACTTCCAGTggtgttggtggtggtggtggcacAACATTTCAATTACCCATAAATATGAGCAATACAATGGGTGGAATAAATACCACAACTTGTACGACCACTACAACCAGGAATAATGTCTCTGTGACAAATATCAAATGTGAAGTGGATGAAGGAGGTAATTCTTCATCTTCAACCAATGGCAATATAGTATCGGTAGGTTTCTATAATGGCACCAGAGCAATAAGTGGGGGAAGTGTAATAACCGCGGGTCATGGCATAAGAATACCAGTGACTAAAGCGGAAGATTCAGATTCAGAAACGGAACtaacaaatatagaaaatttaaaggtAACACGCCGAGTGGCCAGTTCATCATCTAGTGCGGGTAATCATCATAATGGTCCCAGGCCCATGTCTTGGGAGGGTGAGCTGTCGGAAAATGAAGATACCAGAGAAGCAGAATTAATGGATACAGATACCACCATGAGTAATGGTGGCATGCAGCAGGAACCCTCAAATGCTGTGGCGGTAATTAAAAGTGAAGCCACTACCACCACGCCCTCAACAGCGGCAGGGAGTGGAGGATTAATAAAAAGCGATTCCGAACATTATATGTTAGATGCCCAACAAATGGCAGCTGGTGGCGGTGGTGGTATATATCATCCCAAATTAAAATTGGCACCCACACAAAGTGATcccattaatttgaaatatgagCCTCCTGATCATAATGCTCTAGTGAATTCACCGTTATTGGCCCGCCAAAAGTCTACCACAGCTTTGCCTCATTTACCTGCCAATCCAAGTCCAGATTCTGCCATACATTCCGTTTACACCCACAGTTCACCTTCACAATCTCCCCTGACTTCGAGGCATGCCCCCTACACTCCTTCTCTGTCACGTAACAATAGTGATGCTTCTCATAGCTCGTGTTATTCTTATTCGTCGGAATTTAGTCCCACCCATTCACCCATACAGGGAAGACATCCTGCACCACATGGTGTATATGGTAGTTTTAATGGAGCCACGGCCAACAGCTTACAACATTCCGCTTTACTCTATAGACCCATGATGGGTTCCGCACAAACGTCACAATCGGGAAAATTGGAGACAGCAACAAGTGAAGTGCAAAATTTGTCCATGGATGCCGCCACCTCTTCATCATCGTCTGCTACATTTAATATGACTAGTGATTCTTCGGGTTTACCCGCCTCTCCGGCTGCAGGCATTTCCCGACAACAACTTATTAATTCGCCTTGTCCCATCTGTGGTGATAAAATATCGGGTTTCCATTATGGCATCTTTTCTTGTGAATCTTGTAAGGGATTCTTCAAGCGTACCGTCCAAAATCGCAAGAACTATGTGTGTGTTCGAGGAGGACCTTGTGCCGTGAGTATTACCACACGTAAAAAGTGTCCTGCCTGTAGATTCGATAAATGTCTGCAGAAAGGCATGAAATTGGAAGCAATACGTGAAGATCGCACAAGAGGAGGACGCTCAACTTATCAATGCTCTTATACTTTACCCAATTCCATAATGAGTCCTTTACTCTCGCCcgagcaacagcagcaacaaaactCTTCTCAAAATCTTATGACAGGACAACAACATTCACAGCTACAACATCAACTTCAACAACGTCTCAATCCTCCTTTACAAACGGCGCATCAATCTAATGGCTATGGTGGGCCAGCTTCTAATTCAGCTGCTGGTAACACTGGAACCACAACCATAAAAACCGAACAAACGGATACGTATTTAAAGAACATACCTACAGCTGCTCATTCGCCACATTCATTGAATGGCTTGAATACATCATCAGCGTCACATCGCTCACATGCCCATACTACATCCTCCTGCTCCTCCACTTCCGCCTCTTCCTCCGCTTCCTCCAATTCACTGCATCACAACAGTATTCCCCAGcttttacaagaaattatggatgtTGAACATCTTTGGCAATATACCGATGCCGAACTGGCTCGTCTTAATCAGCCATTGACCTCATCCTCATCATCCACATctcttaattcaaattctacGGATTCATCTGCAGCTGCCAATCAAATGACCAATCCACTGCTGGCCAGTGCAGGTCTATCATCTAGCACCAATCCGGATTTGATTGCCCACTTGTGTAAAGTGGCCGACCATCGTTTGTATAAGATTGTGAAATGGTGCAAAAGTTTGCCCCTCTTCAAGAACATATCGATTGACGATCAAATTTGCCTGCTCATCAATTCTTGGTGTGAACTTTTACTTTTCTCCTGTTGCTATCGTTCCATAGATACACCGGGAgaaattaaaatgtctttagGCAAAACCATAACACTGCCTCAAGCTAAATTAACTGGTTTTCAGCCCTGCATTGAACGAATGCTGAATCTGACAGATCATTTAAGACGTTTACGTGTTGATCGTTATGAATATGTTGCGATGAAAGTCATTGTATTGCTGCAATCAGatACTTCCGAATTACAAGAACCTGTTAAGGTTAGAGAATGTCAAGAGAAGGCTTTGCAAAGTTTACAGGCCTATACATTGGCCCATTATCCAGAATGTCCATCGAAATTTGGCGAATTGTTATTACGTATACCCGATTTACAGAGAACTTGTCAGTTGGGCAAAGAAATGTTATCGATTAAATCCCGTGATGGCAATGATTTTAACTTATTAATGGAACTTTTAAGAGGAGAACATTGA
- Protein Sequence
- MSTIKTENITGGGGAVVTTSSGVGGGGGTTFQLPINMSNTMGGINTTTCTTTTTRNNVSVTNIKCEVDEGGNSSSSTNGNIVSVGFYNGTRAISGGSVITAGHGIRIPVTKAEDSDSETELTNIENLKVTRRVASSSSSAGNHHNGPRPMSWEGELSENEDTREAELMDTDTTMSNGGMQQEPSNAVAVIKSEATTTTPSTAAGSGGLIKSDSEHYMLDAQQMAAGGGGGIYHPKLKLAPTQSDPINLKYEPPDHNALVNSPLLARQKSTTALPHLPANPSPDSAIHSVYTHSSPSQSPLTSRHAPYTPSLSRNNSDASHSSCYSYSSEFSPTHSPIQGRHPAPHGVYGSFNGATANSLQHSALLYRPMMGSAQTSQSGKLETATSEVQNLSMDAATSSSSSATFNMTSDSSGLPASPAAGISRQQLINSPCPICGDKISGFHYGIFSCESCKGFFKRTVQNRKNYVCVRGGPCAVSITTRKKCPACRFDKCLQKGMKLEAIREDRTRGGRSTYQCSYTLPNSIMSPLLSPEQQQQQNSSQNLMTGQQHSQLQHQLQQRLNPPLQTAHQSNGYGGPASNSAAGNTGTTTIKTEQTDTYLKNIPTAAHSPHSLNGLNTSSASHRSHAHTTSSCSSTSASSSASSNSLHHNSIPQLLQEIMDVEHLWQYTDAELARLNQPLTSSSSSTSLNSNSTDSSAAANQMTNPLLASAGLSSSTNPDLIAHLCKVADHRLYKIVKWCKSLPLFKNISIDDQICLLINSWCELLLFSCCYRSIDTPGEIKMSLGKTITLPQAKLTGFQPCIERMLNLTDHLRRLRVDRYEYVAMKVIVLLQSDTSELQEPVKVRECQEKALQSLQAYTLAHYPECPSKFGELLLRIPDLQRTCQLGKEMLSIKSRDGNDFNLLMELLRGEH
Similar Transcription Factors
Sequence clustering based on sequence similarity using MMseqs2
- 100% Identity
- iTF_01259264;
- 90% Identity
- iTF_00350235;
- 80% Identity
- iTF_00350235;