Basic Information

Insect: Coccinella septempunctata
Gene Symbol: Baz2b
Assembly: GCA_907165205.1
Location: OU015574.1:52464359-52500341[+]

Transcription Factor Domain

TF Family: MBD
Domain: MBD domain
PFAM: PF01429
TF Group: Unclassified Structure
Description: The Methyl-CpG binding domain (MBD) binds to DNA that contains one or more symmetrically methylated CpGs [2]. DNA methylation in animals is associated with alterations in chromatin structure and silencing of gene expression. MBD has negligible non-specific affinity for DNA. In vitro foot-printing with MeCP2 showed the MBD can protect a 12 nucleotide region surrounding a methyl CpG pair [2]. MBDs are found in several Methyl-CpG binding proteins and also DNA demethylase [1].
Hmmscan Out: # of c-Evalue i-Evalue score bias hmm coord from hmm coord to ali coord from ali coord to env coord from env coord to acc

1 2 1.3e-10 1.1e-06 29.4 0.0 4 51 675 724 673 733 0.90

2 2 0.012 1e+02 3.8 0.0 50 73 745 767 739 771 0.90

#	of	c-Evalue	i-Evalue	score	bias	hmm coord from	hmm coord to	ali coord from	ali coord to	env coord from	env coord to	acc
1	2	1.3e-10	1.1e-06	29.4	0.0	4	51	675	724	673	733	0.90
2	2	0.012	1e+02	3.8	0.0	50	73	745	767	739	771	0.90

Sequence Information

Coding Sequence: ATGGATAAAGAGAATGGAAAGAGTAGCGAAGGTAACTCAGGCTCCAATAAACATTCTAACCAATCGGATCCGGCCTCTCTGCTCGATGCAGCCAGCTTATTTGGAGCTTACTGGCCCCGAGGAGATGCAGCAGCGGCCGCCAACCTGTTCGCGGCTGGAGGCGGTTTCGGCATTCCCCAGCATCCGGCGGCTGCCGCGGCCGCCGCATCCGGCATGCCCTTCGGCCTCATGCCGCCCAGTTCGCCGGGAGGCAGGGGCGCGATGCCCAACTTCCCGACCTCGTCGGTGGCGGCGGCATACAGCAACGCGTACACCAACACGCTGTCGGTCGCGGCCAGTCAAGCGGCTAGCCTCGGCATACCGGCTGCAAGTGCAGCATGGTGGTCGATGGCCTCCCACCTGGCGGCCCAGGACTACCTCGCCCGCCTCCAGGCGTCCGGCCTGAACTTCCCCTCGTTGGCGGACCCCTACGCCTCCCTGGCCGGCCTACCCTCCCTCTCCGGCTCCTCGCACCACGGCCAGGGCAAGTCGAAGAACTCCAAGGGCGGCTCCAAGTCGCACGGCAACGCCAAAGACAAATCCTCGCCCTTCTCGCACCACCACCAGCAGCAGCAGCGATCCTCGCCCTCGCTGAAGATGAGCTCTAGTCCGGCGCCGACGTCGTCGAAGGCCTCCTCCAAGAACTCCCCCGGCCTGACCATCCAGCCCGCCTCCGCCGGGCGCTACCAGCAGCAGCAGGAGAAGAAGGCGTCCAAGTCGGCTGCGTCCGCGCTGAACGACATGACCTACAACATGAAGCAGCTGGAGAAGCTGAAGAACAGCGGCAACAACGTGAGCATCAGCTCGAGCGATTCGATGGGAGGGAAGATGTCGACGTCGTCGAGCATCTTCAGCAGTCCGATGAACATGGTGAGCGGGTCGGATAAGGGCGCCGTGACGTCGGCGGTGTCGAGCGCCAATTCGATCAGCAGCGTCGGCTTGCCTTCCAGTATTTTAAGCGATCCAAATTCGATACTAGGCGGCGTTCGCCTACCTCCAGATACAGAAATAATCAAATATACCTCATCGATAGTCGGCCCTAAGGTACCCGGTACCACCAACCGAGGTAGAAAAAAGACAATATCTCTAGATCCTCCCTTGGTGAGCGTTCATCCCTCAACTTCCCTGGACAGATCCAACAAACGACTGAAATTGAACGATTCTCAAGAGGACCATCAGCAAATGAACTCGCACGATAGAATAGAACTGATAAAACTGCCACCGACCAACGGCAGTCCTTCGGGTATGTCGGGATCGCCGTACAGCAGCAATAACGGCTCGGAGTCGACGGGGGAAGCCCCGCTCAATCTGTCCCTCAAATCGTCGACGCCTACCTCGTGCAGCACGAATCCATCCCTCAACTCCCTGAGCAACATGTCGGCCAGCATAGGCATGGACAGAGTTTCGCGAAGGAAGCCCGGCCCGAAACCCAGACGGGTGATACCGGCGGCGTCCCAGCCGCCGCCCGCGACGCCCAGCTCCTCCCTGATCCAGATGTTCGCGTCCGCCGATTCCCCGCGACCTCCGAGTCGCAACGAGGGTTCCGACGGCGGCAGTTCCACCTCGTCGACGTCGGCCACGGCCGCGAACGCGGGCGGCTCCTCCTCCTCCAACCACAAGGAGGGCAGACCGAGGAACCTGGGTAGGGGCGTGAGCAAGCCGAAGAAGAACACCGTGGCTTCCCTCCTGGCTCAGAGCAGGGCTTTAGGGATAAAGCCCATGCCCATGTTGGACCCTAACACTTCGATGAACCAGCAGCTCAGCTACCTGAAATCGAACATACTGGCCGCGCAGCAGTACATCAACGAGGCCGGCGGCGACGAGAAGATGTTCAACAAGCTGCTCCAGGAAAAGTTCAAGGGTACCCTGAGCGATTCCAGCACGGTGGACGCTTCCACTGACTCGGACAACATGTCCGATTCCAATCACACCGATTCGGAGATGGAGGTCGAGCTGCCGGTCAAGAAGCAGAAGCAGTACGACGAGAGGGCGCTGCGCGTGCCGCTGGAGTTAGGTTGGAAACGTGAAACTGTGATCAGGGGACTGACCAAAAACGGCGGTTTGAAAGGCGACGTTACTTACTCGGCACCCGAGTGCTCCAATAAATTCAAACAAATGTCAGATGTCACTCAGGTAAGTGGTATGATCGCGGATCATGGATGGATTTTGGAACCTAACGAAACGGTATTTTCTGCGCAGTATCTAGATAGTCAGAACATCACGGAATTATCCAGAGAAAACTTCACCTTCAGCTGTAGGGTTATCCTGGGCAACTACCTCCAACCCATGCCTCCCGAGATGGCTGTGGATAGCGAATATGTCCAACTGACCGAAGAGGATGTCACAAAAAGATTGGAGGAGTTAAAATCGGCCATGAGAACAAACCTGTCGGTAGAACAACGAATAGAATTGGCCAGGAAACAACAGGCCGTCAGGGCAGCTGCTAGGTTGGATAGGGAGCAGGCCAGGATAGCCAAGGAGATCGAGAGGTCCGAGCGTCAGGAGGCCGCCAGGAGGGACAGGGAGATACGATCTCAACAAATGATGGAGGCTAAGAGAAAACGTCAAGAGGAAATGGAGAGACAGAAACAGGAAGAACAGCAAAGGAAACAACAGGAACGGGAACGGCGAAGACAGCACATGGCCCTTGTGAAATCGCTGGAGAGCAGGAGGAAACTGGAGGAGAGGGAGAAGAAGAAACAGCAACTGCTGGCCGAGAAACAGGCCAACAAGGAGAAGAAGATGGAGCAGAGGCGGATGGAGATGGAGATCTTGAGCGAACTGAGGAAACCCTGCGAAGACCTGGAACTGGACCAGAAGCCTCTGCCGGAACTGGAGAGGATACCCGGATTGAAACTACCCGGGCAGGCTTTCGGGAACGTCCTCATGGTGTTCGAGTTTCTGCACAACTTCGGGGAGACCCTGGGCTTTGACATGGACTCCCTGCCCACCCTGGACTCCCTCCAGCAGGCGCTGATGCCCAACGAACACTCTTTCGAGGCGGAAGAAGAACTGTTCTCGATCATGACCCATCTGCTGGTCTGCGCCATCGAAGATCCGGGTATTCCTAACCCGGCCAGACACACCACCATCCTGGGACAGAGCCTGAGACAGGCGGACATAACCCACGTCAACCTCTCGGAGATCCTGAGGATATATCTTTACGCGAACGCGACGGGGGAGGTTAAGGCCCTGACGGGGGTGCATTTCGAGAGGGAGCGCGAGAAGAGGATAGCCGACCACCATCAGAACGACGACGAGATGCAGGTCACGCAGCAGGGCAAGAACTCGCAGTACTACGAGATCCTGCACGACAACGAGACGTGGAAGCTGTCCAACATGCTCAAGGACAAACCCTTCATGGCCCTATCGCCGACCCGGAAGTCCGAGATACTGGCCTACATATGCAACGAGCTGCTCCAGAACAAGGCGGTGATCCGGCAGATCGAGGGTTCGCTGGAGCAGGTGGCCCAGCTGAAGAAGGAGAAGTGGCTGTTGGATAACAAGATCAGAAAGTTGAAATTGTTGCATGGGAAGAAGGTCAGGTCGGAGGCCGTGGAGAAGGTGCATAAGATTGGGGATATGGACGGTTCAGAGTCGGCGGTGGACTCCCCGTCTTTGCATAAAGATGACCTATTGGACGACGAGGACAACGAGATGAGCGACAACGAGAGTCTTGCCACCCAACCCGAAGAGGAGGAAGACGCCAAGCTGAGCGGCGAAGAGCTCGGCAAGAAACTGGAGAAACTGATAAAAACGTCGGAGAGCCAACTCCAAGCCCTGAACATCTCCACCCAACAGCTGAGGGCCACCTGCTTCGGCCAGGACAGGTTCTGGAGGCGGTACTGGCACTTCCCCAAGGCGGGCGGCATCTACGTCGAAGCCATGGAGTCCGCCGAGCCAGACCTCCTCCAGCAGATCTCCGACGAGGAGAGCAAGACGCACGACATAATCGACACCGCTCACCTGGTCGACTGCCAGGAGAGGACGGAAGAGGCTCGGCTATGCGACGAAGAAAACGACGAGAACGAACACAGGAAGACGCCGAACAGATTGGAGAGCGTGGAGAACGGCAACGCGCTGCCGGACGGGGACGACAACAACCTGGTGGAGTTGCAGAAGAGCGTGGACGACGTCGTCCAGAGCTTGGAGAAGGAGCGGGAGATGAAACGGGAGGAAGAGGAGGAACCGTTGAGCAGCAGGAAGTTCAACCTGTTCGAGAAGCTGGGCCAGTGCATGGAGAGGGAGAACAAGACGGAGGAGGATCTCAGGGCCGACGTCAAGGCCGAGGTGAAGGAGGAGCTCAAGAACGAGATACTGAACGAGCTCAAGTGCGAGATAAAGACGGAGTGTGTGAAGGACGAGGAGGACGCCAAGGGGGAGACGGAGACCAAGTGGTTCAGCGTGCTGAGCAGGGAGGGCACTTGCGAGGAGGTGCATCTGACGGCTGGCAACAAGTGGGACAACGGCGCCGTCACCAGGGACAACGTGACCGAACTGAAGATACCGGTGTTTCCGCATCCGAACTCGGCGGCAGGGGGCGGCGGTTCCGCGTCCTCCGGCTATACGAACGCGGAGAACTGCGACAATCTGCCGCCGCTGCTGATAACGGCGGAGGAGAGCGCCCAGCTGGAGTACATCAAGAAGCACGGCATGCCGAAGTCTTGCCCGAAGAAGAGCGTGCCGGTGGAGAAGCGGTACGGTTGGTGGAAGGTCACGAAGATCGACGAGTTAAAAGAAATCCTGGAGAACTTGCACGTCCGCGGCATACGCGAAAGGGAACTGAAGAGAAATTTCAACAGTATCATGCAAGCGATGTATCCCACGCTGAGGATACACATAGAAGAGGGTAACAAGGAATTGACGGAGCTGTCCACGGAACACATCGACGACGTCATGTTCATGGAAGGCGGGGCGCCGTATCCCGATCAGAAGGACGCCTGGAACAAGGCCATCGCGGAGAGAGTGGACGCGTCTCTGCTAGAACAGGTAGAAGCTCTCGAGGAGAAAGTGGCCAACGCCAGTATGCAGGTGAAGGGGTGGAAACCGCCGGGCAGGGACGGCCCACCCGTACCCCCCGAATACATGATATACACCATCAGGGAGCGACTGGCCTCGTTGGAATTGAACATCGAAAGGAGATACCTCAAGCCACCGCTGGGAGTCAACACCGGCGATCCCAACCTGGCGGCGATCGCTCAAGAGACCACGGGCGCCTCGTCGTCGACGTCGTCGTCCCAGCCGCCCACCCCGGGCGTGGACGACATACCGAAGGGTCTGGCAACGTGGCGCGAGGCCCTCAACCGTAGCCAGACCTCGGCGCAGCTCGCGATGTGCCAATATTCCTTGGAGGCGTCCATCGCGTGGGACAAGAGCATCATGAAAGCTAACTGTCAATTCTGCCATAGTGGGGACAATGAGGACAAACTGTTACTTTGCGACGGTTGTGATCGAGGTTATCACACCTATTGCTTCAAACCCAAGATGGAAAACATTCCAGAGGGAGATTGGTACTGTCACGAATGCATGAATAAGGCTACAGGTGAGAGGAACTGTATCGTGTGTGGTAAAAAACAGGCCACGACCGGTACGAAACTCGTGCTTTGCGATCTGTGCCCGCGCGCCTACCATCTGGACTGTCTGCAGCCGCCCATAACGAAGATCCCCCGCGGTAAATGGTACTGCCTCAATTGCATCTCGAAGAAACCCCAGAAGAAGGTCAAGAAGAACAATAACAAGACGCCGAAAGAAGCTGAATCGACTGAACATCCTCCTCCACCTAGCCCTGCCCCGTCTCACAGCTCCGTGGCGACGAACGAAGACCAGTCGACGATAACGAACTGCAACCAGAGCGACATCTCCAACTCCAGCATGTGCAACACCATGTCGCCGTCTTCCCAAACGCCCAAAAAAGACAGGCAGTCCAAGAAATTGATAAAGGAACTGGCCCCCTGCAAGGCGATCCTGGAAGATCTAGAGTGCCACGACGACGCTTGGCCTTTCTTGTTGCCAGTCAACACCAAACAATTCCCCACGTATAAGAAGATAATAAAGACCCCGATGGACCTGTCCACCATCAAGAAAAGGTTGCAGGATATGTACTATAAGAGCAAGGAGGAGTTTATCGCGGACGTGAGACAGATATTCAACAATTGCGAAATATTCAACGAGGACGACAGTCCGGTAGGTAAGGCCGGCCACATGATGAGGCAGTTCTTCGAGGCCCGTTGGAACGAGATGTGTCTGAACCACAGTTGA
Protein Sequence: MDKENGKSSEGNSGSNKHSNQSDPASLLDAASLFGAYWPRGDAAAAANLFAAGGGFGIPQHPAAAAAAASGMPFGLMPPSSPGGRGAMPNFPTSSVAAAYSNAYTNTLSVAASQAASLGIPAASAAWWSMASHLAAQDYLARLQASGLNFPSLADPYASLAGLPSLSGSSHHGQGKSKNSKGGSKSHGNAKDKSSPFSHHHQQQQRSSPSLKMSSSPAPTSSKASSKNSPGLTIQPASAGRYQQQQEKKASKSAASALNDMTYNMKQLEKLKNSGNNVSISSSDSMGGKMSTSSSIFSSPMNMVSGSDKGAVTSAVSSANSISSVGLPSSILSDPNSILGGVRLPPDTEIIKYTSSIVGPKVPGTTNRGRKKTISLDPPLVSVHPSTSLDRSNKRLKLNDSQEDHQQMNSHDRIELIKLPPTNGSPSGMSGSPYSSNNGSESTGEAPLNLSLKSSTPTSCSTNPSLNSLSNMSASIGMDRVSRRKPGPKPRRVIPAASQPPPATPSSSLIQMFASADSPRPPSRNEGSDGGSSTSSTSATAANAGGSSSSNHKEGRPRNLGRGVSKPKKNTVASLLAQSRALGIKPMPMLDPNTSMNQQLSYLKSNILAAQQYINEAGGDEKMFNKLLQEKFKGTLSDSSTVDASTDSDNMSDSNHTDSEMEVELPVKKQKQYDERALRVPLELGWKRETVIRGLTKNGGLKGDVTYSAPECSNKFKQMSDVTQVSGMIADHGWILEPNETVFSAQYLDSQNITELSRENFTFSCRVILGNYLQPMPPEMAVDSEYVQLTEEDVTKRLEELKSAMRTNLSVEQRIELARKQQAVRAAARLDREQARIAKEIERSERQEAARRDREIRSQQMMEAKRKRQEEMERQKQEEQQRKQQERERRRQHMALVKSLESRRKLEEREKKKQQLLAEKQANKEKKMEQRRMEMEILSELRKPCEDLELDQKPLPELERIPGLKLPGQAFGNVLMVFEFLHNFGETLGFDMDSLPTLDSLQQALMPNEHSFEAEEELFSIMTHLLVCAIEDPGIPNPARHTTILGQSLRQADITHVNLSEILRIYLYANATGEVKALTGVHFEREREKRIADHHQNDDEMQVTQQGKNSQYYEILHDNETWKLSNMLKDKPFMALSPTRKSEILAYICNELLQNKAVIRQIEGSLEQVAQLKKEKWLLDNKIRKLKLLHGKKVRSEAVEKVHKIGDMDGSESAVDSPSLHKDDLLDDEDNEMSDNESLATQPEEEEDAKLSGEELGKKLEKLIKTSESQLQALNISTQQLRATCFGQDRFWRRYWHFPKAGGIYVEAMESAEPDLLQQISDEESKTHDIIDTAHLVDCQERTEEARLCDEENDENEHRKTPNRLESVENGNALPDGDDNNLVELQKSVDDVVQSLEKEREMKREEEEEPLSSRKFNLFEKLGQCMERENKTEEDLRADVKAEVKEELKNEILNELKCEIKTECVKDEEDAKGETETKWFSVLSREGTCEEVHLTAGNKWDNGAVTRDNVTELKIPVFPHPNSAAGGGGSASSGYTNAENCDNLPPLLITAEESAQLEYIKKHGMPKSCPKKSVPVEKRYGWWKVTKIDELKEILENLHVRGIRERELKRNFNSIMQAMYPTLRIHIEEGNKELTELSTEHIDDVMFMEGGAPYPDQKDAWNKAIAERVDASLLEQVEALEEKVANASMQVKGWKPPGRDGPPVPPEYMIYTIRERLASLELNIERRYLKPPLGVNTGDPNLAAIAQETTGASSSTSSSQPPTPGVDDIPKGLATWREALNRSQTSAQLAMCQYSLEASIAWDKSIMKANCQFCHSGDNEDKLLLCDGCDRGYHTYCFKPKMENIPEGDWYCHECMNKATGERNCIVCGKKQATTGTKLVLCDLCPRAYHLDCLQPPITKIPRGKWYCLNCISKKPQKKVKKNNNKTPKEAESTEHPPPPSPAPSHSSVATNEDQSTITNCNQSDISNSSMCNTMSPSSQTPKKDRQSKKLIKELAPCKAILEDLECHDDAWPFLLPVNTKQFPTYKKIIKTPMDLSTIKKRLQDMYYKSKEEFIADVRQIFNNCEIFNEDDSPVGKAGHMMRQFFEARWNEMCLNHS

Similar Transcription Factors

Sequence clustering based on sequence similarity using MMseqs2

100% Identity: iTF_00020282; iTF_00998685; iTF_01023899; iTF_00965190;
90% Identity: -
80% Identity: -