Basic Information

Gene Symbol
Aef1
Assembly
GCA_001014335.1
Location
JXOR01000784.1:172365-174438[-]

Transcription Factor Domain

TF Family
zf-GAGA
Domain
zf-GAGA domain
PFAM
PF09237
TF Group
Zinc-Coordinating Group
Description
Members of this family bind to a 5'-GAGAG-3' DNA consensus binding site, and contain a Cys2-His2 zinc finger core as well as an N-terminal extension containing two highly basic regions. The zinc finger core binds in the DNA major groove and recognises the first three GAG bases of the consensus in a manner similar to that seen in other classical zinc finger-DNA complexes. The second basic region forms a helix that interacts in the major groove recognising the last G of the consensus, while the first basic region wraps around the DNA in the minor groove and recognises the A in the fourth position of the consensus sequence [1].
Hmmscan Out
# of c-Evalue i-Evalue score bias hmm coord from hmm coord to ali coord from ali coord to env coord from env coord to acc
1 4 4.1e-05 0.12 11.9 0.5 11 48 61 102 52 106 0.79
2 4 5.7e-05 0.17 11.5 0.0 21 50 103 132 100 134 0.87
3 4 0.0023 6.7 6.3 0.0 21 52 131 162 129 163 0.88
4 4 0.00026 0.77 9.3 0.1 21 48 159 185 157 191 0.88

Sequence Information

Coding Sequence
ATGGCGCTAATAGTTAAAAATGCCAACACATTGAGCGATTCAAGATTAAAGAGTCCTGAATCATCAAGTTCTGGCGTCCGAAAGATTGAACCTGTGAAAATGTTGCAGCAAACAAAGGGTGAATTTTACACgacaattacaataaaaattccacCGAAGGAGCAAAAGAACCCAATTAAGTCAACGGCGAAACCTTCATCCCGTAACAGTAGCTCAGCGGTAGGCGAAAAACCATTTCAATGTGAGGTGTGCGAGAAACAATTTCGTCAACTCAGCACGttatcaaatcattttaaaatccatacaGGAGagaaaccatttaaatgtaCGATCTGTGAAAGGGAATTTCGGCAATCAAGTACTCTTACAAaccatatgaaaattcatactGgGGAAAAACCATTTAGTTGTAGTTACTGCGGGCAACAATTCCGGCAGTTGAGCACCCTAACGAACCACTTAAAAATACACACCGGTGAAAAACCATTTGAGTGTGTACTCTGTAAGAAACAGTTTCGTCAATCGAGTACTTTAaacaatcatattaaaatacattttggtGATAGGCAAGGATTCCCAATGAACGGACaaactattaaaattgaacaagtGGAAGCAAGTACATGA
Protein Sequence
MALIVKNANTLSDSRLKSPESSSSGVRKIEPVKMLQQTKGEFYTTITIKIPPKEQKNPIKSTAKPSSRNSSSAVGEKPFQCEVCEKQFRQLSTLSNHFKIHTGEKPFKCTICEREFRQSSTLTNHMKIHTGEKPFSCSYCGQQFRQLSTLTNHLKIHTGEKPFECVLCKKQFRQSSTLNNHIKIHFGDRQGFPMNGQTIKIEQVEAST

Similar Transcription Factors

Sequence clustering based on sequence similarity using MMseqs2

100% Identity
iTF_00348393;
90% Identity
iTF_00348393;
80% Identity
iTF_00348393;