Cfuc010689.1
Basic Information
- Insect
- Coboldia fuscipes
- Gene Symbol
- Mbd2
- Assembly
- GCA_001014335.1
- Location
- JXOR01000993.1:83127-84443[+]
Transcription Factor Domain
- TF Family
- MBD
- Domain
- MBD domain
- PFAM
- PF01429
- TF Group
- Unclassified Structure
- Description
- The Methyl-CpG binding domain (MBD) binds to DNA that contains one or more symmetrically methylated CpGs [2]. DNA methylation in animals is associated with alterations in chromatin structure and silencing of gene expression. MBD has negligible non-specific affinity for DNA. In vitro foot-printing with MeCP2 showed the MBD can protect a 12 nucleotide region surrounding a methyl CpG pair [2]. MBDs are found in several Methyl-CpG binding proteins and also DNA demethylase [1].
- Hmmscan Out
-
# of c-Evalue i-Evalue score bias hmm coord from hmm coord to ali coord from ali coord to env coord from env coord to acc 1 2 5.7e-18 1.1e-14 53.2 0.3 1 59 5 83 5 101 0.84 2 2 1.2 2.3e+03 -2.3 0.0 37 46 104 113 103 116 0.81
Sequence Information
- Coding Sequence
- ATGAATGTGACTATAGAGAGAAAGCGGACAGACTGCAATGCACTTCCGAAAGGATGGCAGCGAGAGGAGGTCCTCCGAAAGTCGGGTCTCTCCACAGGAAAAGTTGATGTATACTATTATAGCCGAGGTGTAAGATCCGATATTTCATTAGTACCACCAATCAGACAAACAGCATCAATATTTAAACAGCCAGTAACGGTGTATCGGAAATACAGTGATAGCAAACAAAAGTCTGATTTAAAACATGGTATTCAAGAGAAACCGAAACAAGTATTTTGGGAAAAAAGGCTTGAGGGATTACGCGCTTGTGATCCAACAGGCAGTGAATTTTCTGTAATTCAATTACCTAAGGGATTGAAAGCAGTAGGACCGGAGGTAGATAATAATACTTTATTACAATCAGTTGCTACGGCTTTGCATGTATCATCAGCGGCAGTAACAGGGCAAACCGAACCGAAAGCTGCCCTACAAACTAATTCTGGTGTATTTCTAAACCCCGACCAACCATTAATGTACAGCATCAATGTCACCGAAGATGATATTAGAAAGCAGGAGGAACGAGTGCAATTAGCGCGTCAACGATTACAAGAAGTATTGGATGCTTAA
- Protein Sequence
- MNVTIERKRTDCNALPKGWQREEVLRKSGLSTGKVDVYYYSRGVRSDISLVPPIRQTASIFKQPVTVYRKYSDSKQKSDLKHGIQEKPKQVFWEKRLEGLRACDPTGSEFSVIQLPKGLKAVGPEVDNNTLLQSVATALHVSSAAVTGQTEPKAALQTNSGVFLNPDQPLMYSINVTEDDIRKQEERVQLARQRLQEVLDA
Similar Transcription Factors
Sequence clustering based on sequence similarity using MMseqs2
- 100% Identity
- -
- 90% Identity
- -
- 80% Identity
- -