Cmar014200.1


Basic Information
Transcription Factor Domain
Sequence Information
Similer Transcription Factors

Basic Information

Insect
Clunio marinus
Gene Symbol
l(2)dtl
Assembly
GCA_900005825.1
Location
CVRI01000054.1:969546-977188[+]

Transcription Factor Domain

TF Family
zf-C2H2
Domain
zf-C2H2 domain
PFAM
PF00096
TF Group
Zinc-Coordinating Group
Description
The C2H2 zinc finger is the classical zinc finger domain. The two conserved cysteines and histidines co-ordinate a zinc ion. The following pattern describes the zinc finger. #-X-C-X(1-5)-C-X3-#-X5-#-X2-H-X(3-6)-[H/C] Where X can be any amino acid, and numbers in brackets indicate the number of residues. The positions marked # are those that are important for the stable fold of the zinc finger. The final position can be either his or cys. The C2H2 zinc finger is composed of two short beta strands followed by an alpha helix. The amino terminal part of the helix binds the major groove in DNA binding zinc fingers. The accepted consensus binding sequence for Sp1 is usually defined by the asymmetric hexanucleotide core GGGCGG but this sequence does not include, among others, the GAG (=CTC) repeat that constitutes a high-affinity site for Sp1 binding to the wt1 promoter [1].
Hmmscan Out
# of c-Evalue i-Evalue score bias hmm coord from hmm coord to ali coord from ali coord to env coord from env coord to acc
1 12 0.00044 0.033 14.9 1.3 3 23 737 758 735 758 0.95
2 12 1.6e-05 0.0012 19.4 1.3 1 23 951 973 951 973 0.98
3 12 1.5e-07 1.1e-05 25.8 0.3 1 23 979 1001 979 1001 0.99
4 12 1.2e-07 8.9e-06 26.1 1.3 3 23 1009 1029 1008 1029 0.99
5 12 4e-07 2.9e-05 24.5 3.3 1 23 1035 1057 1035 1057 0.99
6 12 0.002 0.15 12.8 1.6 3 23 1065 1085 1063 1085 0.96
7 12 6.6e-06 0.00049 20.6 1.2 1 23 1091 1113 1091 1113 0.97
8 12 2e-07 1.5e-05 25.4 2.7 1 23 1119 1141 1119 1141 0.99
9 12 1.2e-05 0.0009 19.8 1.5 1 23 1147 1169 1147 1169 0.99
10 12 7.1e-08 5.3e-06 26.8 1.9 1 23 1175 1197 1175 1197 0.99
11 12 6.4e-08 4.8e-06 27.0 0.8 1 23 1203 1225 1203 1225 0.98
12 12 1.6e-06 0.00012 22.5 4.4 1 23 1231 1253 1231 1253 0.98

Sequence Information

Coding Sequence
atgactaaaataaataacataacAGCTAGACTAATTAATAGGCAATATGGAAAATATTATGAAAAATCTTATGATAATGCTCTAGTAAGACTGATGGTGAGACCATGGGATAACTGGAGAGGAATAAATCCTTCAGGAATAGGAGCAGACTTTAATCCAGATCCGCCAATATTTGCGGCAAAATTTGCAAATACTGAAAACTATAATCACATTCTTGCGGTTGCCAACGAGGATGGAAGAATTGCACTACAAAATACTTTTGTTAAGAACTCTACAAGTGAAGATTTATCACTTGAAGGCGATCAATGCCATTACaaTGCAGTTTTTGATATCGCATGGATGCCTTATCATTTAAAGTTAATCAGTGCAAGTGGGGACCATACTGCCCGATTATGGGACGTTACAGAAAGCAAACTTATTAATATCCGAGAGTTTTGTGGACATTCACGATCAGTTAAAGTTGCTGCCTTTAGGAAGAACGATTGTTCTGTGTTCTCAACAGGTGGACGTGATGGAGCAATTCTTATCTGGGATTTGAGAAGTAACACAAACAACGAAGTTCAAAAAATTGACAATCGCATTTATAATGCACACATTGGTGGCGGTCCAACAACTCCATCAACAAGACGAAGAGGAAACAGATATGCAACTCCAAAGAATCAAACAAATGTCAGCAATTCGAGTGTGACTGGACTGATCTTTCAAAATGAGAACACTTTGGTGTCTTGTGGACCTGCAGACGGCGTCATCAAAATGTGGGACCTTCGAAGATGTTATTCAACACTTAAAAAAGAACCAGTAGCAAAGCATAGTTTGCCTTATGCTGGAAATTCCACATTAAAAGGCTtcacaaatttaattgttgatGATTCAGAAACGAGACTTTTCGCCAGTTGTATGGACAGCAAAATTTACAGCTACAACATCTCAGCTTATTCAAAAGAGCCGACAATGATTTATTCCGGTCTTCAAATTAATTCGTTTTATATAAAATCATGTTTAAGTCCTGATGGACGTTATCTGTTGAGCGGAAGTAGTGATGAAAAAGCTTACATTTGGAACATTGAAAATCCTCATCCTGTTGCATCATTGGTTGGACATAATTTTGAAGTAACTTGCGTTGCTTGGAGtaatcatcaaaataatttggATGGAGGAAATATGTGCATTGTCACTTGTTCAGATGATGCTTGTCACAAAGTATGGCGTGTTGGTCCGGAGTTTCTTCCAGAAGACGAAAGACTTTCTTTACGTGGTCATAGTGAACTTggtgaaaaatattatcagtATGAAAAGTCTAAACAAGttttaagaagaaagttaaaaGATTTAAGTCCTCGAACTTCGAATgcacaaaacaaacaaatcagAATGACTCCAACAAAAGCTGAAATCTCATCattgaaaagaagttttcaggAAATGTGCGCCGATGATCCAGAAATTGTTattgaaggaaatgaaagaaaacgacCGAATATTGAAGCTAAAGGAAGAAGACTTTTCCCTTCATCGCCATCTTCATGTATAGATCATTATTCAACTACTTCAGCTTCAAGACCACTTGAGACACTTTTTGAAGAGTTGAGTTCAACACAAAgccaaaattttcaaaatcttgtATCGTCTCCAGTTAAACGTCAAATAAACATCATAAAGTCACCGGAAAATTTACGTGTGAGTAAATCCAAGTCGCTAAATAAAGATCGAATGGAACCTTCCGTGAATTCTCCTACGATGAATCTTCCAAATTTTGTGATTGATGGTGATGCACCACATTTGAGTTTAATGTCACCCCATCGAAAaactaagaaagaaaatgtagATTGGTTGACAAAAATGCGTAAACAAAAATTACTGTCATTAAATAATGCATTGGAAAAAGCGACCACTGCCACAGAAATACAAAATGATCAGAACGATAAACTTCTCAAATctatagaaaataaaagtgaaagtcaagagaaaaagaaaagtcaaaagaaaacagaagCGACTATCTTAAAtaATGCGAttcgcaaaaaaaaactaactTGCGAATCGCGAGTGATGCAAAAGTTCGAAGCACAAAAACAAATGCAGAATTTTGGCTTTCCAACTGGCTCAAGAATTATTCTTTATGGAGGCAAAACCTGCGTTATTGCACCAGAACAAAAGACAAACACATCTACACCGACTGTAATTGGAACTATTGAGAGCCCTCAAATATGTCATTTATGCCAAAAAGAGTTTTCTTCGATAGAGACTCTTCAAAACCACATCAAGGAGCAGCATGTTGATAGTAAATTTTACCGCAATATTATCGCAGTTTCGACTGTAGGTAATCAAGTTACAATGATTCCAACTCCACTTCAACAATATCAAATAGGAACAAGTgcagtgaaaattgaaaaagatttccatCCAATACATGCAAAGTTGATTCCAGAAATTATAAAACCAAGCAATTCCGAGTTTGCCAACTCAGTTACTAATTTAAATATAGCTCATCCTGTAATTCAACATATTCAAATACAACcgagggaaaaagaaaaagcgaaCGTTGTGCAAGTCATAAAACAGAATCCAGTTGAATATCACATACAGCAACAGGAACATGCTGCCATGGTGGTTGCATCGATGAGCCAAAAATCAGGTGTTTGTAATCCATTTTTAAATAGTACCATTAAGTATGAACTTCATGGACAACCAGTTCAACTTGTATCAGAAGTGTATCCTCAAATGTTAGCTGAAGCTCCGAAATCCGACGACTTAAATTCACAGTCATCAGTGTCATCACCAGGATCTTCAGTTAATGTTCAAAATGCAACTGGCCCAATGCTTAGCAATGGTGAAACCATGGAAAAGCAACATAAATGTTTGGTCtgtgataaatttttcacGACTGTTGGAAACCTAAATATTCATCTAAAAATACATGCAGGAGAAAAACCTTACAaATGCACTGTGTGTGGGAAAGGATTCATTCAATCTAATAATCTTGCAACTCATATGAAGATTCATACAGGAGAAAAACCTCATGGTTGCCAGATATGTGGAAAAAGATTCAGTCAatctaataatttaaaaactcaCATAcGAACACACACAGGAGAAAAGCCATTCAAATGTACGCTTTGTGAGAAAAgctttaatcaaaaaaataatctcaCAACACATTTGAGAACTCACAGTGATTATCATCCTTCAAACTGTAGCATGTGCAATCAAACCTTTATGTCATTTAATGAGCTGTTTTCACATATGAGGGATCATGCTGAAGAGAAGCCTCACGTTTGCAGCGTTTGTAATAAAGTTTTCAGTgttcaaaatgatttaaatgatCACATGAAACAGCATTCGAATCCTAAGCCCTATAAATGTGATATTTGCCAAAAGCAATTTACACAATCTAACAATTTAAAAACTCACATCAAAACTCATATTTATCAAGATCCATTTAAATGCAGTATGTGCACAAGATCGTTTCAAGATCAAGAAGAATATCAATTGCACATgAGAGTTCATACTTTTGATAAACCTTACGAATGTACATATTgtggaaagaaattcattcaaagtaataatttaaaaactcaTGTGAGAACACATACTGGAGAGAAACCTTACGctTGTACTGTTTGTGGAAAGTCATTTAATcagaagaataatttaaatacgcaCTTGAGAGTTCACACAGGCGAGAAACCTTTCGAGTGTCATTTATGTGATCGACGATTTAAccaatcaaataatttaaataaacactTAAAGACACATGGACAAGAGAAGGAAATCAGTAAAGCTATGGAAacagaaatggaaaaaatgatgaacaacgtcattcaacaacaataa
Protein Sequence
MTKINNITARLINRQYGKYYEKSYDNALVRLMVRPWDNWRGINPSGIGADFNPDPPIFAAKFANTENYNHILAVANEDGRIALQNTFVKNSTSEDLSLEGDQCHYNAVFDIAWMPYHLKLISASGDHTARLWDVTESKLINIREFCGHSRSVKVAAFRKNDCSVFSTGGRDGAILIWDLRSNTNNEVQKIDNRIYNAHIGGGPTTPSTRRRGNRYATPKNQTNVSNSSVTGLIFQNENTLVSCGPADGVIKMWDLRRCYSTLKKEPVAKHSLPYAGNSTLKGFTNLIVDDSETRLFASCMDSKIYSYNISAYSKEPTMIYSGLQINSFYIKSCLSPDGRYLLSGSSDEKAYIWNIENPHPVASLVGHNFEVTCVAWSNHQNNLDGGNMCIVTCSDDACHKVWRVGPEFLPEDERLSLRGHSELGEKYYQYEKSKQVLRRKLKDLSPRTSNAQNKQIRMTPTKAEISSLKRSFQEMCADDPEIVIEGNERKRPNIEAKGRRLFPSSPSSCIDHYSTTSASRPLETLFEELSSTQSQNFQNLVSSPVKRQINIIKSPENLRVSKSKSLNKDRMEPSVNSPTMNLPNFVIDGDAPHLSLMSPHRKTKKENVDWLTKMRKQKLLSLNNALEKATTATEIQNDQNDKLLKSIENKSESQEKKKSQKKTEATILNNAIRKKKLTCESRVMQKFEAQKQMQNFGFPTGSRIILYGGKTCVIAPEQKTNTSTPTVIGTIESPQICHLCQKEFSSIETLQNHIKEQHVDSKFYRNIIAVSTVGNQVTMIPTPLQQYQIGTSAVKIEKDFHPIHAKLIPEIIKPSNSEFANSVTNLNIAHPVIQHIQIQPREKEKANVVQVIKQNPVEYHIQQQEHAAMVVASMSQKSGVCNPFLNSTIKYELHGQPVQLVSEVYPQMLAEAPKSDDLNSQSSVSSPGSSVNVQNATGPMLSNGETMEKQHKCLVCDKFFTTVGNLNIHLKIHAGEKPYKCTVCGKGFIQSNNLATHMKIHTGEKPHGCQICGKRFSQSNNLKTHIRTHTGEKPFKCTLCEKSFNQKNNLTTHLRTHSDYHPSNCSMCNQTFMSFNELFSHMRDHAEEKPHVCSVCNKVFSVQNDLNDHMKQHSNPKPYKCDICQKQFTQSNNLKTHIKTHIYQDPFKCSMCTRSFQDQEEYQLHMRVHTFDKPYECTYCGKKFIQSNNLKTHVRTHTGEKPYACTVCGKSFNQKNNLNTHLRVHTGEKPFECHLCDRRFNQSNNLNKHLKTHGQEKEISKAMETEMEKMMNNVIQQQ

Similar Transcription Factors

Sequence clustering based on sequence similarity using MMseqs2

100% Identity
iTF_00347201;
90% Identity
iTF_00347201;
80% Identity
iTF_00347201;