Cdip000266.1
Basic Information
- Insect
- Cloeon dipterum
- Gene Symbol
- sptf-2
- Assembly
- GCA_949628265.1
- Location
- OX451259.1:2893683-2898388[-]
Transcription Factor Domain
- TF Family
- zf-C2H2
- Domain
- zf-C2H2 domain
- PFAM
- PF00096
- TF Group
- Zinc-Coordinating Group
- Description
- The C2H2 zinc finger is the classical zinc finger domain. The two conserved cysteines and histidines co-ordinate a zinc ion. The following pattern describes the zinc finger. #-X-C-X(1-5)-C-X3-#-X5-#-X2-H-X(3-6)-[H/C] Where X can be any amino acid, and numbers in brackets indicate the number of residues. The positions marked # are those that are important for the stable fold of the zinc finger. The final position can be either his or cys. The C2H2 zinc finger is composed of two short beta strands followed by an alpha helix. The amino terminal part of the helix binds the major groove in DNA binding zinc fingers. The accepted consensus binding sequence for Sp1 is usually defined by the asymmetric hexanucleotide core GGGCGG but this sequence does not include, among others, the GAG (=CTC) repeat that constitutes a high-affinity site for Sp1 binding to the wt1 promoter [1].
- Hmmscan Out
-
# of c-Evalue i-Evalue score bias hmm coord from hmm coord to ali coord from ali coord to env coord from env coord to acc 1 10 0.00022 0.016 15.7 0.2 3 23 385 407 384 407 0.95 2 10 0.02 1.4 9.6 5.3 1 23 413 437 413 437 0.98 3 10 0.0002 0.014 15.9 2.8 1 23 443 467 443 467 0.97 4 10 0.0097 0.7 10.5 0.4 3 23 475 497 474 497 0.94 5 10 0.0004 0.029 14.9 2.9 1 23 504 526 504 526 0.98 6 10 0.0002 0.014 15.9 1.1 3 23 535 557 534 557 0.93 7 10 0.00044 0.032 14.7 1.1 5 23 569 587 563 587 0.88 8 10 0.00021 0.015 15.8 0.6 1 23 593 617 593 617 0.98 9 10 0.0035 0.25 11.9 0.1 2 23 624 647 623 647 0.96 10 10 0.17 12 6.6 1.8 1 23 656 681 656 681 0.94
Sequence Information
- Coding Sequence
- ATGTCCTGGAAAGAGGTGTTGAAGCCGTCGATAGGCGAATTCGAGCGGCAGGTCTCGCTCAACAGACTGTCCGTGTGCTCGGACGGACAGGACAGCAACGAGGGCTTCAGCGAGGAGAAGCTGTGCATCGGCATGGAGATGCTGCCAGAGACGTCCGGCTCGACGTACGAGTTCGTCTGCGTGGACGAGTGGCTCAAGGGACGCACCGAGTCCATGTCGAGCATGGACATGGACGTGTCAATGACGGATGCGGCCAGCAAGGAGAACGCCAATCTGTCCGAGCTGGACCAGTTCCTCACGCCCAAAGGGGCCGTCGACCTGTGCATAGCCAACGAGTCGCAGGCCCTCAGCGAAGACGCCTCCAGCTTGTTGCTGTCCGACGATCTCCTCTGCAAGCCGGATAAACCCAATAAAACTCCACTAGATAATCAGCTGTTTCTGGCGGAGGACGAGTCGAGGCTGAAGGATGAGGACAGTTTGGTTGGGCGACGGGCAAGCTGGACTGAACAGTTGGAGAAAGACAAATCAAACTGGGACTTGATGTCCAACACGAGTCACAAGAGTCACGAGTTGGTTAAAGAGGTCGACTTCCCTGAATTCAATTTGGTTCCTCCGTTCGATCCGATTTGCTCGATCGAGATGCCAGACGGCAAGGAGCTGATTGAAGACCAGCTTTTGGACAAAGTTGTCGATTTGATTCCAAAGGATGATGAGCAAAACCGAGATCCTGTGATGACCAGTGTACAGGAAGAAGAGACTGTGCTTGTCGACTCGGTTTTGGACGCTAacgatgaattaaaaaatgaagaggaCCTGGCCATCATAGCAATTTCGGCTAACGCAGACAACACCGCCCAAATCATCATCAGCACCGGTCCGACGGTGTTTCAGGTCAAAGAAGACGGAGCTCAGAAAGAATCGCTGAACGTGCAGGTTATTGGAGATCAAAGAACTGATGAGCAAGTGATTTCGCTCAGAAATGGGACTGATGAGGATGAAGAAAATGATTTGACAATTGCCAAGTCtgacgaggaggaggaggaaacaAATGAAGAAGACGAACAGCCCTTGATTGAAGCTTTGGCTGCAATCGGCATCAAGGTCGACTCCCTCATGTACGTGAAGACGGACAGCCAGCATCGCATGTGGCTGTGCCCAGTTAAAGACTGCCGAAAAACCTACGCAAAGCAGAGCGCCCTAAAGGTCCACATACTTAGTCATTATGGCCTCAGACCCTTCAAGTGCGACTACGAAGGCTGTTTTTGGTCGTTTTACACGCATTTCAGACTTAAAAGACACAAAAACACTCATTTAAAGAAGAAAGATTTTGTGTGTACCTACGAGGGTTGCGATAGAAAGTTCACAACCATCTACAATTTGCACACGCACCAGAAGCTGCACGAGCGGCCTGCCGAAAACGTGTGCACAGTGGAAGGATGCAACGCGAGCTTCCAGACAAAGCGCAAGCTGGAGCTGCACCTGAAGCAACACGATTCAAGCCACGCCCCGTACAAGTGTCACTACTGCAAGAGAGGCTACTACTCGATCAACTCGCTCAACATGCATATCAGGGGCCATGAGCACAAAGAGGAGGAGGTCATTTGCCAATGGGACGGCTGTGGCAAAAGGTTTGACAAACCTTGCCGACTGAGAGCCCACATGCGATCTCACACTGGAGACAGACCCTACAAATGCATCTATGAGGGTTGCAAATGGTCATTCTCAACTGCAAGTAAACTGAGGAGACATTCGCAAAAGCACACGGACGAGAGGAATTTCAAATGCAACGTTGACGGATGCTCGAAAGCGTTTCTCAGACCTGAGCATCTGCGCGAGCATATTTTGACGCACGATGGAACCAAGAATTGGAAATGCCCTGTTCCAGGCTGTGAAGCTAGATTTACTGCCAAGAGTAGTTTGTACGTTCATGTTAAGAAACACAATTCTCCCTCAAACAAGGACACATTTGAGTGTCCGTTCGAGAATTGCAATCAAAAGTACCTGCGGAAGGCAAGTTTGCGACACCACGTGGTGAAAAATCACCAGGTTCCGACCACTGATGcTGATTCTTCAACAGAAAATTCAGTAGGATCGAGCAACTTCTTGGCTTTTGTTCCTTTGGATGGGCAGGAGATTTTGATTGGTCAAACCTACTCCGTGACTGAAGCAATGGACAACAATGTGGTTCTCTCTACAATAAACCCTGCGGATATAATGCTGACAAGCGATCATGAACTGCCAACTTTAGTTCCTGGAGACGATTCTCACACTAATCTGAACAGCCTCAATGTCACCAGTAATCTCTCAAATCTATCTGCTGAAGAATCTGAGGACGACAGCCACATAGGGTGTGCGCGAACTAacctgccgctgccgctggtTCCACGCAAAGCGAATCGAACCTCTGCCAATGTGCTGCCAGCGCCGGCGTTGCTGCCTGACGACATTTTTAACGACCCTCTGCTGGCCAATCCACAAGGTATCGAGTTCCAGATAATGCTGGACACGAGGCAGCGAGACTTCCCTGAGTCGACCATCAATCTGCGCGACTTAGAGTGA
- Protein Sequence
- MSWKEVLKPSIGEFERQVSLNRLSVCSDGQDSNEGFSEEKLCIGMEMLPETSGSTYEFVCVDEWLKGRTESMSSMDMDVSMTDAASKENANLSELDQFLTPKGAVDLCIANESQALSEDASSLLLSDDLLCKPDKPNKTPLDNQLFLAEDESRLKDEDSLVGRRASWTEQLEKDKSNWDLMSNTSHKSHELVKEVDFPEFNLVPPFDPICSIEMPDGKELIEDQLLDKVVDLIPKDDEQNRDPVMTSVQEEETVLVDSVLDANDELKNEEDLAIIAISANADNTAQIIISTGPTVFQVKEDGAQKESLNVQVIGDQRTDEQVISLRNGTDEDEENDLTIAKSDEEEEETNEEDEQPLIEALAAIGIKVDSLMYVKTDSQHRMWLCPVKDCRKTYAKQSALKVHILSHYGLRPFKCDYEGCFWSFYTHFRLKRHKNTHLKKKDFVCTYEGCDRKFTTIYNLHTHQKLHERPAENVCTVEGCNASFQTKRKLELHLKQHDSSHAPYKCHYCKRGYYSINSLNMHIRGHEHKEEEVICQWDGCGKRFDKPCRLRAHMRSHTGDRPYKCIYEGCKWSFSTASKLRRHSQKHTDERNFKCNVDGCSKAFLRPEHLREHILTHDGTKNWKCPVPGCEARFTAKSSLYVHVKKHNSPSNKDTFECPFENCNQKYLRKASLRHHVVKNHQVPTTDADSSTENSVGSSNFLAFVPLDGQEILIGQTYSVTEAMDNNVVLSTINPADIMLTSDHELPTLVPGDDSHTNLNSLNVTSNLSNLSAEESEDDSHIGCARTNLPLPLVPRKANRTSANVLPAPALLPDDIFNDPLLANPQGIEFQIMLDTRQRDFPESTINLRDLE
Similar Transcription Factors
Sequence clustering based on sequence similarity using MMseqs2
- 100% Identity
- iTF_01046585;
- 90% Identity
- -
- 80% Identity
- -