Basic Information

Gene Symbol
-
Assembly
GCA_018150985.1
Location
JAECWU010000379.1:4296221-4301629[-]

Transcription Factor Domain

TF Family
zf-C2H2
Domain
zf-C2H2 domain
PFAM
PF00096
TF Group
Zinc-Coordinating Group
Description
The C2H2 zinc finger is the classical zinc finger domain. The two conserved cysteines and histidines co-ordinate a zinc ion. The following pattern describes the zinc finger. #-X-C-X(1-5)-C-X3-#-X5-#-X2-H-X(3-6)-[H/C] Where X can be any amino acid, and numbers in brackets indicate the number of residues. The positions marked # are those that are important for the stable fold of the zinc finger. The final position can be either his or cys. The C2H2 zinc finger is composed of two short beta strands followed by an alpha helix. The amino terminal part of the helix binds the major groove in DNA binding zinc fingers. The accepted consensus binding sequence for Sp1 is usually defined by the asymmetric hexanucleotide core GGGCGG but this sequence does not include, among others, the GAG (=CTC) repeat that constitutes a high-affinity site for Sp1 binding to the wt1 promoter [1].
Hmmscan Out
# of c-Evalue i-Evalue score bias hmm coord from hmm coord to ali coord from ali coord to env coord from env coord to acc
1 14 0.0022 0.17 12.4 0.4 1 23 164 186 164 186 0.97
2 14 3.3 2.7e+02 2.4 3.8 1 23 192 215 192 215 0.95
3 14 0.00095 0.076 13.6 2.6 1 23 432 454 432 454 0.98
4 14 0.045 3.6 8.3 1.6 1 23 506 529 506 529 0.97
5 14 0.0094 0.75 10.4 2.4 5 23 795 813 792 813 0.91
6 14 0.0095 0.75 10.4 0.7 1 23 819 842 819 842 0.96
7 14 2.6 2.1e+02 2.7 0.2 2 20 882 901 882 903 0.94
8 14 0.0026 0.21 12.2 0.4 1 23 922 945 922 945 0.97
9 14 0.015 1.2 9.8 1.8 1 23 1142 1165 1142 1165 0.96
10 14 7e-05 0.0056 17.1 2.4 1 23 1180 1202 1180 1202 0.99
11 14 7.8e-06 0.00062 20.1 0.4 1 23 1207 1229 1207 1229 0.99
12 14 0.00017 0.013 15.9 5.6 1 23 1235 1260 1235 1260 0.97
13 14 0.0003 0.024 15.2 0.5 1 23 1265 1289 1265 1289 0.96
14 14 0.00068 0.055 14.0 0.8 1 23 1295 1318 1295 1318 0.97

Sequence Information

Coding Sequence
ATGCCACTCAGAAAGATAAAAGCCAGTGGCGAAATTGATTATAAATTAGCGTGTCGTTGTTGCCTCAAATCCGACGCGGAGTTTTACAAACTAGATTCTGTAATGGTGGCGCGCAATATTGGCTACGATGAAAGTAATGCGTTCGGCAGTGATGGTAGTGAAAAGATACCATTATTGCGTTGTTTGCTCTTTTGCATTCGTACCGAAAACGTTCCGGAGCTGCCGCAGTACATTTGTCTTGGCTGCAGCAAGAGTTTGCAAATAGCATATCATTTTCTACAAAATGCACTGCGTGCACATGAGATTCTATGCAATAAAATATGCCCTGATAAATCTAAAGGACAGCGTGCCGTGCGTTTAAATGGCCAGCAAAACCATATCATTGGGAACAACAGCAGCGCAAAGGAGCGCACTCTGCAAAAGCAGCAGCAGCAGCTTGAGGACTGCGGCAATGATGAGGGCTCATTAAAGCCGCGAAAAACCGTGCGTCACGAATGTAAAGTATGCGGCGCTGTTATATACAATCGATTGGAGCTTAAGCAGCATATTCGTTTGCATTCAGACGTAATTGCGCATAGCTGCACCATGTGTAGTTTTGTCACATTAAAGCAGTACCAGTTAATTCAGCACTACAAATCTTTTCACAACTTAACTGCAGCGCAATGTGAACGAAAACTAAAATCATCTATTATATATACATCGTCAACTGCTTCGCCACAACCAAAGCCGTCACAAACTGTAATATCCGAACAACCAGCAATCAAATCAGCTAATAGCAGCATGGGCGAGGAAAATTCGGTGGTGTGCACATTAGAAGATATGGAGATGCTAATACCAACCGTGTTGAGACCTGAAGACTATGAAACACCGCACATTGATGCAGAACATTTGCAAGAATTGGAAAAACAGTTGACTGAAAGTATAGAAACAGCGGCAGCCACAGCAACAGTTCTTGATGAAAGTCTTCCGGCATTAGAACTGCCTCGAAGTATCATCAATAAAACTACGTCTAGCAATGCACAAAACATTTGTGAAGGTGGTAGCAATTTGACTATAGGCACAGAGTTTTTAGTAATGCCTGATGGCTCGCTGCAACAGATAAACGGCAATGGTGTGGTCATAGAGTACATAAATGCCACGGATGGTGACGTTAAAAACAAAACAGATGAGGATTTGATTACAGCAGCAGAAAACAGCATTGTACCAATGGATATTGATGTTAATGAGCTCATTGTTGAAGAAGTGCAGCCAAATTCAAAAAGGACGAGAGGTGCACCTCGCGCCACCGTAAGATACAAATGCCAACAGTGTCCCAAAACCTTTGCAACAGCGGCGCGTCTTAAATGCCATCAGTTAACCCACAGCAATTTGCCCAAATTTTATTGTGATCAATGCGCCTTCTACTCGCTGCGCAGCTCGGAACTAATGCAACACCATAAGGAAATGCACAACGTTGAGTCCACAAGCGTGCTAAAGGATGGTCATGCTTCTGTACCAACAGATGAGAGTAAAATCTACTCATGCGATATGTGCCTCTTTGAGACCAAAAGCTCTGGCCAGTTGCGTTTGCATTATAACAAAAAGCATAGGACTGCAGCGTCAGATGTGGAGCTGCGGCCAAGTTGGTGCGTAGAAAATTCCAGTCCCGCTGACACTTCTACACAGACAGATGCAAACAGTGGCAAGCAGCAACACGTGCCAGAATTTCCGCTGGGAATCCAATATCCACGGCCGACAAACGTAGCAGTTAACATGGCAAGCCCAGAGCAATTGGCCGCTGCTGTAGCTACAAGTATGGAGAATGCTGTGCAGTTCACAACGGACACGACACTTCTTTGTAATTCCAGCTCGGGCGCGCAAGCAGCCGTTGCAAACGTGCCACCTGTTTTGGTCTCAGCTGCAACTAATCCATCGACCATTTTGCCGGTGGTTGACAGCGAAAACAATTTCTCAATATTTCCACAAATCTCAGCCAACATGGCAAGCAGCGCAGAGCAAATGGCAACGCTGCCCACTTCTACAGCCAATGTTGCTGTTTCCATAATAGGCGATATGCAGGATTTCATAGATGACACTGATGTGGCAGCTATATGCACTATACCTGCAGATGGTCTGCCTGTAGTCGATGGCGATGATATTGTCATAGACAACAACAATATTAACTTGGACTTTGATGCTGAAAATCTCTTTGAAGACTTNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNACAATCTCTACATTTACAAAAGCCCTATTGCATATTTTGTAATAAAAAGTTTACCAGTCAGTACAAGTTTGAGAATCACATGTTCTTGCATCGTGGCTTGGCTCCGTATCGTTGCGAGCTCTGCACCAATATTTATAACAAAAAACGAGCTCTTATACGGCATTACAAAGCCGTGCACAAGCGCATGCCCACGCGTGATATGGTACAGGCTAAAGGTGACAAAATATCTCTAAATCGTACGAATATTGAAAAGTTGCACCTGGACAAAGATAAAGCGCCCGCCTTAATGTGCGCCAAATGTCCTTTCGAGTGCGAACTGGAAACTGATATGCCCAAACATTTAAATGCTCATCATGGAATTAATGATGGTGTTACTTGTCATGCCAAAGAAGTTTTCATTATACGCAAACTGCCTTTTGAGTGCCCCCGTTGCATACGCTCATTTGCTGCAAAAGGTACGCTTACGCGACATTTACAGCGCAGTCATCTAGTGGACACAATAATCGAGCTACAATCTCCTCCAATGACCACAAGCTCCGCGACTACAAGTTCCGCGACCACAACCACCACTTCTACACCGACTACAACTTTACCAAATGCTAATGAAATTGCGTCAAACAAGGCGGTGCCTGAGCAGCTTGTGGCAGGCGAATGCGCAAGAACAGGCGTTTTGGCAAAGCCGCCACAAAGATATCAATATAAATTTCATGACACAACTGAGACGACCCCGATGACGACAAGCGCTGAGTTAACAACTAGTCTGCACATTAGTACTAACAGCAATGAACCCACAATGACGCCATTGCCTACAAATACAGCATCCACGCTTTTTCCTTCACCCACATTCCATTCGTTTGATTTTGATTACTATGATTTAATGGATGAGACGCATGCGGCTGTTCAGCACCTTGTTAAGCGCGAACCAGAGGCCAACAACAGCTATACGGACGTATTGACCAAATCCACTAACTACAGTCATGTGCTGCGAGATGATAAATTGCTGCCCACGGCACTGCTTTGTCAGGACACTTCGCCGGTTAAGGATTTGCGCAGTTATTTGCCACGAACGCCCATCTTTGTGTGCCGGCAATGCAATTACACCTGTGATGAACTGAGTAAACTTAACCAGCACCAAGCCATGGAACATGCCAATAATGGTGATACCACACTGCCGCGTCGTAACTATGACTACAAGTGCACTATCTGTAATAGCACATACCGAACAATTTCACTGCTCCAATACCATATGAAGCGTCATGCCAAGCGCAATTACAAATGTGACTTGTGCCCCAAAACGTTTGTTGTGCGTCCAGAGCTGACCAAACATAGGATAACACATAGCAAAGAGACGCCTTTTAAATGCAACGTTGAGGGCTGTCAAAAGGCCTTCAACTATAAGCATCATCTCAAGCGTCATTACATGTCCACGCACCTGCGCAAGCGTTATACATGTACTATGCCAGAATGCGGCAAAGAATTGGCATCCAGTTCGCAGCTGGCGCAGCACATGCATTTTCACAAGGGCACACATGCGTATAAATGCCCCAGGTGCACCCGTGCTTATACGCGACGCAAGCCTTTACGCTTGCACGCAATGCGTGAGCATCAGTTACAGCTTAGCGAGGATGATCTTGCGGACATATATCGTGCCAATGTGGGCTACACAAATCCCCATGACTTAAGAGTATTCACAGGAAATGGCGAGTTATTGCGGCGTTCCGCAGTTGAAGCTGCTGCAGCAAATAAACGGCGCGCTGAATTAGAGGAAGCCGTTGTAAATATTAGTATTTAG
Protein Sequence
MPLRKIKASGEIDYKLACRCCLKSDAEFYKLDSVMVARNIGYDESNAFGSDGSEKIPLLRCLLFCIRTENVPELPQYICLGCSKSLQIAYHFLQNALRAHEILCNKICPDKSKGQRAVRLNGQQNHIIGNNSSAKERTLQKQQQQLEDCGNDEGSLKPRKTVRHECKVCGAVIYNRLELKQHIRLHSDVIAHSCTMCSFVTLKQYQLIQHYKSFHNLTAAQCERKLKSSIIYTSSTASPQPKPSQTVISEQPAIKSANSSMGEENSVVCTLEDMEMLIPTVLRPEDYETPHIDAEHLQELEKQLTESIETAAATATVLDESLPALELPRSIINKTTSSNAQNICEGGSNLTIGTEFLVMPDGSLQQINGNGVVIEYINATDGDVKNKTDEDLITAAENSIVPMDIDVNELIVEEVQPNSKRTRGAPRATVRYKCQQCPKTFATAARLKCHQLTHSNLPKFYCDQCAFYSLRSSELMQHHKEMHNVESTSVLKDGHASVPTDESKIYSCDMCLFETKSSGQLRLHYNKKHRTAASDVELRPSWCVENSSPADTSTQTDANSGKQQHVPEFPLGIQYPRPTNVAVNMASPEQLAAAVATSMENAVQFTTDTTLLCNSSSGAQAAVANVPPVLVSAATNPSTILPVVDSENNFSIFPQISANMASSAEQMATLPTSTANVAVSIIGDMQDFIDDTDVAAICTIPADGLPVVDGDDIVIDNNNINLDFDAENLFEDXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXQSLHLQKPYCIFCNKKFTSQYKFENHMFLHRGLAPYRCELCTNIYNKKRALIRHYKAVHKRMPTRDMVQAKGDKISLNRTNIEKLHLDKDKAPALMCAKCPFECELETDMPKHLNAHHGINDGVTCHAKEVFIIRKLPFECPRCIRSFAAKGTLTRHLQRSHLVDTIIELQSPPMTTSSATTSSATTTTTSTPTTTLPNANEIASNKAVPEQLVAGECARTGVLAKPPQRYQYKFHDTTETTPMTTSAELTTSLHISTNSNEPTMTPLPTNTASTLFPSPTFHSFDFDYYDLMDETHAAVQHLVKREPEANNSYTDVLTKSTNYSHVLRDDKLLPTALLCQDTSPVKDLRSYLPRTPIFVCRQCNYTCDELSKLNQHQAMEHANNGDTTLPRRNYDYKCTICNSTYRTISLLQYHMKRHAKRNYKCDLCPKTFVVRPELTKHRITHSKETPFKCNVEGCQKAFNYKHHLKRHYMSTHLRKRYTCTMPECGKELASSSQLAQHMHFHKGTHAYKCPRCTRAYTRRKPLRLHAMREHQLQLSEDDLADIYRANVGYTNPHDLRVFTGNGELLRRSAVEAAAANKRRAELEEAVVNISI

Similar Transcription Factors

Sequence clustering based on sequence similarity using MMseqs2

100% Identity
iTF_00336198;
90% Identity
iTF_00338633;
80% Identity
-