Basic Information

Gene Symbol
Bro
Assembly
GCA_037043745.1
Location
JBAMAX010003367.1:82993-83592[+]

Transcription Factor Domain

TF Family
CBF
Domain
CBF_beta domain
PFAM
PF02312
TF Group
Beta-Scaffold Factors
Description
Core binding factor (CBF) is a heterodimeric transcription factor essential for genetic regulation of hematopoiesis and osteogenesis. The beta subunit enhances DNA-binding ability of the alpha subunit in vitro, and has been show to have a structure related to the OB fold [1].
Hmmscan Out
# of c-Evalue i-Evalue score bias hmm coord from hmm coord to ali coord from ali coord to env coord from env coord to acc
1 1 8e-72 9.9e-68 227.4 0.5 1 153 29 177 29 188 0.96

Sequence Information

Coding Sequence
ATGCAACATCCAAATATTCCACCGGCATACGACAATATGGCTTTTGCGCTCTATGAGCAGCCCAAGCCGCGTTTTGTCTTCAAAATGCCACGTGTAGTGCCAGATCAGAAGCTTAAATTCGATAATGATGAATTATTTCGGCGTCTAAGTCGAGAAAGTGAAGTTCGCTACACAGGCTATCGAAAACGCGCTATGGACGAACGTAAACTGCATTTTGCCAACGATTGCCGTGAAGGGTATACGGAAATCTCATTTGTAGCAACTGGCACAAATCTGCAACTATATTTTAATGCCAATCACAATCCATACATGAAGGAACAGGAATGTGACTTTGAAAAGGAACCTGGTAAAGTCTATCTGCGTTCCAGCCTTATAATGAACGGCGTTTGTGTGCGTTTTCGTGGTTGGCTGCAGCTAGAGCGTCTGGATGGTGTAGGCTGTTTGGAATACGACGAACAGCGAGCTTTGCAAGAGGATGCACAACTAAAGCAATTGATCGACAGTCATACTCAACGCGTAGCGGATTCCAAAAGGATTTTTGCGCATACGCCAACTGAGGAAGTTATGCCACCCAATGGCAATGTGCGCATGGGTTGGTAG
Protein Sequence
MQHPNIPPAYDNMAFALYEQPKPRFVFKMPRVVPDQKLKFDNDELFRRLSRESEVRYTGYRKRAMDERKLHFANDCREGYTEISFVATGTNLQLYFNANHNPYMKEQECDFEKEPGKVYLRSSLIMNGVCVRFRGWLQLERLDGVGCLEYDEQRALQEDAQLKQLIDSHTQRVADSKRIFAHTPTEEVMPPNGNVRMGW

Similar Transcription Factors

Sequence clustering based on sequence similarity using MMseqs2

90% Identity
iTF_00338090;
80% Identity
-