Basic Information

Gene Symbol
-
Assembly
GCA_963931855.1
Location
OZ007554.1:99801953-99822364[+]

Transcription Factor Domain

TF Family
zf-C2H2
Domain
zf-C2H2 domain
PFAM
PF00096
TF Group
Zinc-Coordinating Group
Description
The C2H2 zinc finger is the classical zinc finger domain. The two conserved cysteines and histidines co-ordinate a zinc ion. The following pattern describes the zinc finger. #-X-C-X(1-5)-C-X3-#-X5-#-X2-H-X(3-6)-[H/C] Where X can be any amino acid, and numbers in brackets indicate the number of residues. The positions marked # are those that are important for the stable fold of the zinc finger. The final position can be either his or cys. The C2H2 zinc finger is composed of two short beta strands followed by an alpha helix. The amino terminal part of the helix binds the major groove in DNA binding zinc fingers. The accepted consensus binding sequence for Sp1 is usually defined by the asymmetric hexanucleotide core GGGCGG but this sequence does not include, among others, the GAG (=CTC) repeat that constitutes a high-affinity site for Sp1 binding to the wt1 promoter [1].
Hmmscan Out
# of c-Evalue i-Evalue score bias hmm coord from hmm coord to ali coord from ali coord to env coord from env coord to acc
1 18 4.2e-05 0.011 17.9 2.1 1 23 401 423 401 423 0.96
2 18 1.1e-05 0.0028 19.8 0.4 1 23 429 451 429 451 0.97
3 18 2.1e-05 0.0054 18.9 0.5 1 23 457 479 457 479 0.98
4 18 1.8e-05 0.0046 19.1 3.1 1 23 485 507 485 507 0.97
5 18 4e-05 0.011 18.0 4.7 1 23 513 535 513 535 0.99
6 18 7.3e-05 0.019 17.1 5.7 1 23 541 563 541 563 0.97
7 18 2e-07 5.3e-05 25.2 4.3 1 23 569 591 569 591 0.98
8 18 1.3e-07 3.4e-05 25.8 2.4 1 23 597 619 597 619 0.97
9 18 0.00017 0.045 16.0 5.7 1 23 625 647 625 647 0.97
10 18 2.1e-05 0.0056 18.8 6.5 1 23 653 675 653 675 0.98
11 18 3.6e-06 0.00095 21.2 4.5 1 23 681 703 681 703 0.98
12 18 8.4e-06 0.0022 20.1 8.1 1 23 709 731 709 731 0.98
13 18 2.1e-06 0.00054 22.0 7.9 1 23 737 759 737 759 0.98
14 18 7.7e-07 0.0002 23.4 7.7 1 23 765 787 765 787 0.98
15 18 0.00024 0.063 15.5 9.5 1 23 793 816 793 816 0.95
16 18 0.0002 0.053 15.7 0.5 1 23 822 844 822 844 0.97
17 18 0.0009 0.24 13.7 4.4 1 23 854 876 854 876 0.98
18 18 7.5e-06 0.002 20.3 1.7 1 23 882 905 882 905 0.96

Sequence Information

Coding Sequence
atgttacaGCAACATGTCCAGCAACACCATCACGAAAATACAGCTTGCGGTATTAGTGGAGTCATTCATCCTGTTGGCGGGATCGAGTCAGATGTTTCCAAACAACATCATTCACACCATCAGCCATCACACGTATCAGGTCCACAACAACATCTTGGAAAATACTGGGTTGTAACGAATCTTTTTCAGGGTCCAGGTCAGCCGCCATACAATATTGGTGTAACACCAACAACTTCAGCAGTTCCTTCAATACCTCCTCCGATATCTTCGCATTCTAGTGCTTCTGCAACCAAGGCAGCAAACTCTAAGCAGCAGCAGCAAGATCAACAACAGCAACTAGCACCAAATTCCCACACTCAATCGCCATCAGCACATATAGTTTCATCTGTTGGTGCTACATCCCTACAAATACCCAATCCGATGATAAATACAGGAATGAACCAGCATCAGCTTCCAAATGGCACAATAATTGCCGGCCCACGTCATCCTGATTCTTTACATGTTCATGGAACAATGTCCGGCGATGACAATCGACACGTGTCACATGGTATGCAGGACATAAAGGAGGAGAAACCTTTTGCCAATGGCAAGCCAAACATACATATGGCACATGTTAATCCAACATCTTCCATTTCGTCAAAAATGAATTCTGGAAGTGGTGGCAACAGTGTAAACAATGGGCAGTCAACTGATTCAGGAGGTAGTCAAATGGTCAAACTACAACCAGGGTCTGGTTCTGTTCCCGGTAGCAGTGGAGGAGGTAACGAACAAGAAAGCAAACCACCCCACGGCGTTGAAATGTATAAAGTCAATATTGAAGACTTGAGTCAATTTTTATCATATCACGAAGTCTTTGGTAAGATCCATGGGGAAGTAATAAATCAACAGCAAATATCGCACACGGTAACTCATCCTACTACGAATGTATCGACTTCCAATGCCGGTGGAAATACCTCAGTGAGTGGTACTGTTTCCGGTTCACTACCTCCACCACCGTCTACTAATGGAAACTCGATAGTGTCTACCAGTAGCCTAACCAATTCAGGAACTGGTGCCCAAACAGTTCCACCGACAGGCTCAGCCGGTGTACCTACTGCACCTGGTGAACTAATTCTACCCAAGATGGAAAATCAAGGGATTGGTGTTGATCAGAACACTCCATTGCTTGCACCGGACGGAACACCAATCATGGGTGGCACGCATATCTGTGACATTTGCGGCAAAATGTTCCAGTTTCGTTATCAGTTGATTGTGCATCGTCGTTATCACAGTGAACGCAAGCcatttaactgtcaagtttgcGGACAAGGATTCACCACATCGCAAGATCTCACACGACATGGTAAGATTCACATTGGTGGACCAATGTTCACATGTGTGATTTGTTTCAATGTGTTTGCTAATAACGCCAGTTTGGAGCGGCACATGAAACGACATTCTACGGATAAACCTTTTGCGTGTACCATATGCCAGAAGACATTTGCGCGTAAGGAACACCTGGATAATCACTTTCGGAGTCATACTGGAGAGACGCCGTTCCGTTGCCAGTATTGTGCTAAAACATTTACACGAAAAGAACACATGGTGAATCATGTTCGCAAGCATACTGGGGAGACGCCTCATCGTTGCGATATCTGTAAGAAATCTTTTACGAGGAAAGAACATTATGTTAATCATTACATGTGGCATACAGGTCAGACACCGCATCAGTGCGATATATGTGGAAAGAAATATACAAGGAAAGAGCACCTGGCCAATCATATGAGATCGCATACGAATGATACCCCATTTCGGTGTGAGATTTGTGGCAAGAGTTTTAgcagaaaagaacattttaccAACCACATTTTATGGCATACAGGAGAAACCCCTCATCGCTGTGATTTCTGTGCGAAGACGTTCACCAGGAAGGAGCACCTATTGAACCATGTCCGCCAGCATACGGGTGAGTCACCACATCGCTGCACCTATTGCTTGAAGACCTTCACTCGTAAGGAACATCTAGTGAATCACATTCGTCAACACACAGGCGAAACACCCTTCAAGTGCACCTACTGTACCAAGGCTTTCACACGGAAGGATCATATGGTAAATCACATCCGTCAACATACTGGAGAATCACCACATAAATGCACCTACTGCACGAAAACCTTCACCCGGAAAGAACATCTGACCAACCATGTGCGCCAACATACGGGTGAGTCGCCACATCGTTGCACCTATTGCAAAAAAACGTTTACACGCAAGGAACACCTAACCAATCACATACGGTTGCATACAGGCGATTCGCCCCATAAATGCGAATACTGCCAAAAGACGTTCACACGTAAAGAGCATTTGAACAATCATATGCGGCAGCATTCGAGTGATAATCCGCACTGCTGCAATGTGTGCAACAAGCCCTTTACACGCAAGGAACATCTTATCAATCATATGTCGCGTTGTCATACCGGTGACCGACCATTTGCTTGCGAGACTTGTGGTAAAAGTTTTCCCCTTAAAGGCAACTTGCTCTTCCATCAACGTAGCCACACCAAAGGTCAGGAGTGTGAACGTCCATTTTCTTGCGAAAAATGcccgaaaaattttatttgcaaagGCCATTTGGTGTCGCATATGCGATCCCACTCTGGAGAAAAGCCCCATGCTTGCACCATGTGCAGCAAAGCATTTGTGGAAAGAGGAAATCTTAAGCGTCACATGAAGATGAATCACCCGGATGCTGTAATGCCACCACCTCCAACACCTTTACCCGGGCTTCTGACGCAAATCAAACAAGAAATCAAGCCGATTATAATTCCTCATCAACCCCCAACTATGCATACGATACAACAAATCACTTCAACTGCAGGCAGCACAAGTGCAAATAATCCTGGCAACCCTACACTTTTGGCACCTGGTCTGGTTCCAATGGTTACATCTACAATAACTTCACACATAAAGCAGCAATCCCACttacaacaacagcagcaacagcaccaACATCAACATCAATTGCAACAACAACAGCTATTGCAGCTGTCGATTCAGCAAGCAGCTCAACATCAACAAGCTGAGCATcggcaacagcagcagcaacaacaacaacagcagcaacaacaacagcagcagcaacaacagcagcaacagcaacaagttcaacaacagcagcaacatcaGCAACAAAGCCATCAAcagcaccaacaacaacaacaatcgcAACAGCAATCACAACAGCATCAACAGCCTCAACCGCCTTCAGTGCCGTTAGCTCTCATTGGAGCCGATCCCTCAGCTATAGCTCGAGCTGCTATGCAACTTCAGCATTTGCCAACAAACGTTGAACAACATCCAGTTGTTTATTAG
Protein Sequence
MLQQHVQQHHHENTACGISGVIHPVGGIESDVSKQHHSHHQPSHVSGPQQHLGKYWVVTNLFQGPGQPPYNIGVTPTTSAVPSIPPPISSHSSASATKAANSKQQQQDQQQQLAPNSHTQSPSAHIVSSVGATSLQIPNPMINTGMNQHQLPNGTIIAGPRHPDSLHVHGTMSGDDNRHVSHGMQDIKEEKPFANGKPNIHMAHVNPTSSISSKMNSGSGGNSVNNGQSTDSGGSQMVKLQPGSGSVPGSSGGGNEQESKPPHGVEMYKVNIEDLSQFLSYHEVFGKIHGEVINQQQISHTVTHPTTNVSTSNAGGNTSVSGTVSGSLPPPPSTNGNSIVSTSSLTNSGTGAQTVPPTGSAGVPTAPGELILPKMENQGIGVDQNTPLLAPDGTPIMGGTHICDICGKMFQFRYQLIVHRRYHSERKPFNCQVCGQGFTTSQDLTRHGKIHIGGPMFTCVICFNVFANNASLERHMKRHSTDKPFACTICQKTFARKEHLDNHFRSHTGETPFRCQYCAKTFTRKEHMVNHVRKHTGETPHRCDICKKSFTRKEHYVNHYMWHTGQTPHQCDICGKKYTRKEHLANHMRSHTNDTPFRCEICGKSFSRKEHFTNHILWHTGETPHRCDFCAKTFTRKEHLLNHVRQHTGESPHRCTYCLKTFTRKEHLVNHIRQHTGETPFKCTYCTKAFTRKDHMVNHIRQHTGESPHKCTYCTKTFTRKEHLTNHVRQHTGESPHRCTYCKKTFTRKEHLTNHIRLHTGDSPHKCEYCQKTFTRKEHLNNHMRQHSSDNPHCCNVCNKPFTRKEHLINHMSRCHTGDRPFACETCGKSFPLKGNLLFHQRSHTKGQECERPFSCEKCPKNFICKGHLVSHMRSHSGEKPHACTMCSKAFVERGNLKRHMKMNHPDAVMPPPPTPLPGLLTQIKQEIKPIIIPHQPPTMHTIQQITSTAGSTSANNPGNPTLLAPGLVPMVTSTITSHIKQQSHLQQQQQQHQHQHQLQQQQLLQLSIQQAAQHQQAEHRQQQQQQQQQQQQQQQQQQQQQQQQVQQQQQHQQQSHQQHQQQQQSQQQSQQHQQPQPPSVPLALIGADPSAIARAAMQLQHLPTNVEQHPVVY

Similar Transcription Factors

Sequence clustering based on sequence similarity using MMseqs2

100% Identity
iTF_00426545;
90% Identity
iTF_00976727;
80% Identity
-