Basic Information

Insect: Chrysops caecutiens
Gene Symbol: spopl
Assembly: GCA_963971475.1
Location: OZ020569.1:2788747-2793161[-]

Transcription Factor Domain

TF Family: BTB
Domain: zf-C2H2|ZBTB
PFAM: PF00651
TF Group: Zinc-Coordinating Group
Description: The BTB (for BR-C, ttk and bab) [6] or POZ (for Pox virus and Zinc finger) [1] domain is present near the N-terminus of a fraction of zinc finger (Pfam:PF00096) proteins and in proteins that contain the Pfam:PF01344 motif such as Kelch and a family of pox virus proteins. The BTB/POZ domain mediates homomeric dimerisation and in some instances heteromeric dimerisation [1]. The structure of the dimerised PLZF BTB/POZ domain has been solved and consists of a tightly intertwined homodimer. The central scaffolding of the protein is made up of a cluster of alpha-helices flanked by short beta-sheets at both the top and bottom of the molecule [2]. POZ domains from several zinc finger proteins have been shown to mediate transcriptional repression and to interact with components of histone deacetylase co-repressor complexes including N-CoR and SMRT [5, 3, 4]. The POZ or BTB domain is also known as BR-C/Ttk or ZiN.
Hmmscan Out: # of c-Evalue i-Evalue score bias hmm coord from hmm coord to ali coord from ali coord to env coord from env coord to acc

1 3 0.0075 4 9.0 0.0 3 31 135 163 133 197 0.79

2 3 5.1e-17 2.8e-14 54.6 0.0 21 107 808 895 802 898 0.95

3 3 3.5 1.9e+03 0.4 0.0 79 109 899 929 895 930 0.88

#	of	c-Evalue	i-Evalue	score	hmm coord from	hmm coord to	ali coord from	ali coord to	env coord from	env coord to	acc
1	3	0.0075	4	9.0	3	31	135	163	133	197	0.79
2	3	5.1e-17	2.8e-14	54.6	21	107	808	895	802	898	0.95
3	3	3.5	1.9e+03	0.4	79	109	899	929	895	930	0.88

Sequence Information

Coding Sequence: ATGGCTTTGGAACATACGTTTCTTGGGACGTGGGagaTAATAAGCTGCTCCTTTGAAGGGAAACAAGAAACGTCAGGTCTTGAAGGgaTCAAGTTTCGTTTGGATGAGACCGGCGATATAACATGGTACAATGACCTAATTAATCCCCTTCCCGAGTCAAAAGACTGTGATAGCTGCTGCGAATCAGCTAATGTCCTTTTTAGTTGCGAAACTTTTGATGTAAATGAAAACAACCCACGACTCATTTTTGGAGCATTTGCTGGACACAGTATTGAATTCAagacGCACACCTTGACGCCTGCTGATTCTTTGACTTTAGAATGTGAAAACTGGTATTCTTTATTATGTAAACGCCTTAAAGGAGACCAAGCCGTTGGACAGGAGACTGAATTTACTTTTGAGGCGGCATTAAATGAAGGCTACTTCAGTGATGTAGTTGTTAAAAGTTCTGATGGTGTCGATTATCATGTTCACTCAGCTATTCTTCGCCTTAATGGATTTGATTGCAGTATGTGTTGTCAATCTGCTCCAGCTTCAAATGCAGATAGTAGCAAGCGGAATGTGACAACAAATCAAGTTAAAATATCCATTACAATCCCCCATAAAACGAGTGATAGTTATAATGATCAGAAGTTACTGCCAAAATTGAATCTCTCGCCAATTTATCTTTTACCACCTACTGTGGATGTCTTGGGAGCACATAAAATGAGCAATCTATCAAGTTCTTTTAATTGCTTAGCAGCTTCTAGCAACAGTAAAGAAGAAATGGAAGAAAAAATCATTCGAAAATATCCAATGTCGTCATCTGATTCAAATTTGCAAACAAACAGCGCAAACAATATATTCAACTTTTCAAATGATCTATTTTTGAATCCGGTTGAAACAGTGTGCAGTAATCGCAAACCTCCTTTGTCACCTTATCGTGCCAGGAGTCCATCACCATTTCCTAGCTCTTTAGACACACCACCATCATCGCCACTCACCCCAATTGGTGTCCTGTACAGCTTGCCATCATTTATGCTGACTCCAATTTTCCATTGGTTGTATACGGAATCCTTGATGACTAACATGGAAGAAGACACATGTgaaaagttgatcaatttcgCCGAAACTCAACCACCACTTATAAAAATTGTGAATCCTTGTCGGAGGTATCTCAAATTGATACGAATGAGAAAATTTGTAATAGATGTTATTATGGATATGCATGATATtctcaacaaaataatttataccATTAATCCTGCAATAATTTCCCATGAACCAGCAACACTTTTTAATCTTTTTAAGGAATGCCTCAAAGAGGGTGCTGTGGgtTGTGCTAAAATTCTTCAATTctgtaatatttttattaaagatGCCACAGACATATCACGTTTTCAAAAGCACGAAATTATCAAATATGTGAGAACGAGGCTTCCAATTTTCATGTCACAGCTTCATCAACTACTGAAAAATGTATTGAGTGTTTTCATTAGCCTAAGCTTAGAGGAAAAATCTGAGCTAATCATTTACTTAGTACCTGAAATTGAAtctatattaaaaattttaacaaatgtGATAgaggaaatcaaaaattcacttgaaaaaATGTGTAAAGACTTGAAATGCTCACATTTAGATTTGTCTACAGTTGTAGATGAACCTGTTTACAGTCTCACAACAAATCAAGGAATTCAAGATGAAATGCATCGACTCCCCTTTACGAGGCCTACAGTGTATGATATGCCAAATGAAAAGCGTTTAATATCCGCTGAAAATGATCTAAAATTTGTTCTATATATGTATGAGGTACGAAAAATGCGAGACATATACGGTCGTATAGCAGCTGCTTTAGACATTATAAGGGATAAAAAaacGGCATTTTgcgaaatgaatttattaaataagaaGAGTACAATTCACCAAAATCTAGAACAACTAATCTTAGACATACCCACTTATATTttgataatagaaaatatatcaGATCGACTGGATGATAAAATCGGATGGAAAGAATTCAAGTTTTGCTTCAAATTAGCAACCAGCCAAATAAATGGTGTGATCATAAAGCTCCTTGATCATAAACCAGCTCTTCGAGATCCAATAAGTCATATATGCAAACTAGTTCAAAAGGAAGAATTTACGAAATCATTAATTGAAATGGGCCTTCTCGAGTCATCGAATATACTTCAAAACGATTTTAAAACACCAACAGTCAAAACTGCACTATATGACTATAAAAATGTAAagCTAAATTTGactaaaaatttatgtgaaccgCCTATAGTAGCAAACAGCGGTTTATCGAAAAATGCATTGCGTTTGCTACATTCTGGTCAATTATCTGATATGGAATTCGAAGTACATGTCCTGCAAAATAACCACGATCTAGTAGTGAAGGATGATCATAGTTATCAGTGCAGACCTAGCCAAGTTCATACATTTCGTGCTCATAGAGTAATTGTTTCAGCGAGATGTGAATGGTTTAAAAAGGCTCTACTATCTGGAATGCAAGAAAGTATTACTAGAAGAATTGCTATTTCTGATACGTCACCTGTGATATTTAGACGtttattactttatttataTGGTGCTCCAATAGATAAAACTGTTGGGGCCGAACAAATATGTGAATTGATGCTTTTGGCCGATCGATATTCAATAGACGATTTAAAGGAATTATGTGAAAACACTCTAAATGCTCTTATTGACGAAGATTCTGTGGTTTGTCTTCTTGGTATTGCTGATCGCTTTCTGGCATCGGCATTGAAATCAAATTGCTTATCTTTTATATCACAACACGCAAATTTAACAAAGTTAGAGATGTTCAGGGAATTACCGAAATCAATTCAGCTTGAAGTTCAGGATTTGATACATTGGTATGGAAGAGTACCAGATTCGTGGGGTGATGGTTTCAAGCCAAGAAGTAGTTCAAGACATAGTCTAAAAAGTCCATCGAAGCCAAGATCGCGATCACGAAAATCATCACCATCATTTATGTGA
Protein Sequence: MALEHTFLGTWEIISCSFEGKQETSGLEGIKFRLDETGDITWYNDLINPLPESKDCDSCCESANVLFSCETFDVNENNPRLIFGAFAGHSIEFKTHTLTPADSLTLECENWYSLLCKRLKGDQAVGQETEFTFEAALNEGYFSDVVVKSSDGVDYHVHSAILRLNGFDCSMCCQSAPASNADSSKRNVTTNQVKISITIPHKTSDSYNDQKLLPKLNLSPIYLLPPTVDVLGAHKMSNLSSSFNCLAASSNSKEEMEEKIIRKYPMSSSDSNLQTNSANNIFNFSNDLFLNPVETVCSNRKPPLSPYRARSPSPFPSSLDTPPSSPLTPIGVLYSLPSFMLTPIFHWLYTESLMTNMEEDTCEKLINFAETQPPLIKIVNPCRRYLKLIRMRKFVIDVIMDMHDILNKIIYTINPAIISHEPATLFNLFKECLKEGAVGCAKILQFCNIFIKDATDISRFQKHEIIKYVRTRLPIFMSQLHQLLKNVLSVFISLSLEEKSELIIYLVPEIESILKILTNVIEEIKNSLEKMCKDLKCSHLDLSTVVDEPVYSLTTNQGIQDEMHRLPFTRPTVYDMPNEKRLISAENDLKFVLYMYEVRKMRDIYGRIAAALDIIRDKKTAFCEMNLLNKKSTIHQNLEQLILDIPTYILIIENISDRLDDKIGWKEFKFCFKLATSQINGVIIKLLDHKPALRDPISHICKLVQKEEFTKSLIEMGLLESSNILQNDFKTPTVKTALYDYKNVKLNLTKNLCEPPIVANSGLSKNALRLLHSGQLSDMEFEVHVLQNNHDLVVKDDHSYQCRPSQVHTFRAHRVIVSARCEWFKKALLSGMQESITRRIAISDTSPVIFRRLLLYLYGAPIDKTVGAEQICELMLLADRYSIDDLKELCENTLNALIDEDSVVCLLGIADRFLASALKSNCLSFISQHANLTKLEMFRELPKSIQLEVQDLIHWYGRVPDSWGDGFKPRSSSRHSLKSPSKPRSRSRKSSPSFM

Similar Transcription Factors

Sequence clustering based on sequence similarity using MMseqs2

100% Identity: iTF_01432220;
90% Identity: -
80% Identity: -