Basic Information

Transcription Factor Domain

TF Family: zf-GAGA
Domain: zf-GAGA domain
PFAM: PF09237
TF Group: Zinc-Coordinating Group
Description: Members of this family bind to a 5'-GAGAG-3' DNA consensus binding site, and contain a Cys2-His2 zinc finger core as well as an N-terminal extension containing two highly basic regions. The zinc finger core binds in the DNA major groove and recognises the first three GAG bases of the consensus in a manner similar to that seen in other classical zinc finger-DNA complexes. The second basic region forms a helix that interacts in the major groove recognising the last G of the consensus, while the first basic region wraps around the DNA in the minor groove and recognises the A in the fourth position of the consensus sequence [1].
Hmmscan Out: # of c-Evalue i-Evalue score bias hmm coord from hmm coord to ali coord from ali coord to env coord from env coord to acc

1 9 0.46 3.1e+02 2.0 0.0 20 43 31 54 20 59 0.78

2 9 0.79 5.3e+02 1.2 0.0 21 43 60 82 57 90 0.83

3 9 0.072 48 4.6 0.1 25 43 92 110 86 116 0.85

4 9 0.0071 4.8 7.8 0.1 21 44 116 139 113 143 0.90

5 9 0.055 37 4.9 0.0 21 43 144 166 139 171 0.87

6 9 0.028 19 5.9 0.1 21 44 172 195 167 203 0.86

7 9 0.14 92 3.7 0.1 21 44 200 223 197 231 0.80

8 9 0.11 74 4.0 0.0 21 46 228 253 221 259 0.82

9 9 0.91 6.1e+02 1.0 0.3 21 32 256 267 251 281 0.76

#	of	c-Evalue	i-Evalue	score	bias	hmm coord from	hmm coord to	ali coord from	ali coord to	env coord from	env coord to	acc
1	9	0.46	3.1e+02	2.0	0.0	20	43	31	54	20	59	0.78
2	9	0.79	5.3e+02	1.2	0.0	21	43	60	82	57	90	0.83
3	9	0.072	48	4.6	0.1	25	43	92	110	86	116	0.85
4	9	0.0071	4.8	7.8	0.1	21	44	116	139	113	143	0.90
5	9	0.055	37	4.9	0.0	21	43	144	166	139	171	0.87
6	9	0.028	19	5.9	0.1	21	44	172	195	167	203	0.86
7	9	0.14	92	3.7	0.1	21	44	200	223	197	231	0.80
8	9	0.11	74	4.0	0.0	21	46	228	253	221	259	0.82
9	9	0.91	6.1e+02	1.0	0.3	21	32	256	267	251	281	0.76

Coding Sequence: ATGTTATTCGAAAGGAAATCATTTGGGAGATTAGTCTCCATTAAAAAATATACTCGACAAAGTACTTTAAAAAAACATAAACGTATTCACACCGGAGAAAAACCATTTTCATGTGATGTTTGTAATAAAACATTTACTTATCAACATAATTTAGTTGTACATAAACTAATTCATAGCGGAGAAAAACCATTTTCATGTGATGTTTGTAATAAAACATTTACTTATCAACATAATTTAGTTGTACATAAACTAATTCATAGCGGAGAAAAACTATTTTCATGTGATGTTTGTAATAAAACATTTACTCAACAACATAATTTAGTTAGACATAAACTAATTCATAGCGGAGAAAAACCATTTTTATGTGATATTTGTAATAAAAGATTTACTCAACAAAGTAATTTAGTTAGACATAAACGTATTCACAGCGGAGAGAAACCATTTTCATGTGATGTTTGTAATAAAACATTTACTCAACAAAATAATTTAGTTGTACATAAACTAATTCATAGCGGAGAGAAACCATTTTCATGTGATGTTTGTAATAAAACATTTACTCAACAACATCATTTAGTTAGACATAAACTAATTCATAGCGGAGAAAAACCATTTTCATGTAATATTTGTAATAAAACATTTAGTCAACGAAATACTTTAGTTAGCCATAGACGGGTTCATACTGGAGAAAAACCATTTTCATGTGATGTTTGTAATAAAACATTTACTCAGAAAGGTGATTTAGTTAAACATAAACGAATTCACACCGGAGAGAAACCATTTTCATGTGAAATTTGTAATAAAACATTTACTCGACAATATTGTGTAGTTAAACATAAACGTATTCACAATCGATAA
Protein Sequence: MLFERKSFGRLVSIKKYTRQSTLKKHKRIHTGEKPFSCDVCNKTFTYQHNLVVHKLIHSGEKPFSCDVCNKTFTYQHNLVVHKLIHSGEKLFSCDVCNKTFTQQHNLVRHKLIHSGEKPFLCDICNKRFTQQSNLVRHKRIHSGEKPFSCDVCNKTFTQQNNLVVHKLIHSGEKPFSCDVCNKTFTQQHHLVRHKLIHSGEKPFSCNICNKTFSQRNTLVSHRRVHTGEKPFSCDVCNKTFTQKGDLVKHKRIHTGEKPFSCEICNKTFTRQYCVVKHKRIHNR

Sequence clustering based on sequence similarity using MMseqs2