Basic Information

Transcription Factor Domain

TF Family: zf-GAGA
Domain: zf-GAGA domain
PFAM: PF09237
TF Group: Zinc-Coordinating Group
Description: Members of this family bind to a 5'-GAGAG-3' DNA consensus binding site, and contain a Cys2-His2 zinc finger core as well as an N-terminal extension containing two highly basic regions. The zinc finger core binds in the DNA major groove and recognises the first three GAG bases of the consensus in a manner similar to that seen in other classical zinc finger-DNA complexes. The second basic region forms a helix that interacts in the major groove recognising the last G of the consensus, while the first basic region wraps around the DNA in the minor groove and recognises the A in the fourth position of the consensus sequence [1].
Hmmscan Out: # of c-Evalue i-Evalue score bias hmm coord from hmm coord to ali coord from ali coord to env coord from env coord to acc

1 7 0.61 4.1e+02 1.6 0.0 22 49 128 155 123 160 0.82

2 7 0.089 60 4.2 0.1 21 47 155 181 148 188 0.83

3 7 4.5 3e+03 -1.2 0.0 21 40 183 202 178 210 0.74

4 7 7e-05 0.047 14.2 0.1 21 47 211 237 203 244 0.84

5 7 1.5 1e+03 0.3 0.0 21 42 267 288 261 294 0.78

6 7 0.035 24 5.6 0.0 21 45 295 319 289 326 0.80

7 7 0.065 44 4.7 0.0 21 43 323 345 318 349 0.87

#	of	c-Evalue	i-Evalue	score	bias	hmm coord from	hmm coord to	ali coord from	ali coord to	env coord from	env coord to	acc
1	7	0.61	4.1e+02	1.6	0.0	22	49	128	155	123	160	0.82
2	7	0.089	60	4.2	0.1	21	47	155	181	148	188	0.83
3	7	4.5	3e+03	-1.2	0.0	21	40	183	202	178	210	0.74
4	7	7e-05	0.047	14.2	0.1	21	47	211	237	203	244	0.84
5	7	1.5	1e+03	0.3	0.0	21	42	267	288	261	294	0.78
6	7	0.035	24	5.6	0.0	21	45	295	319	289	326	0.80
7	7	0.065	44	4.7	0.0	21	43	323	345	318	349	0.87

Coding Sequence: ATGGCAAATAATTCATTTAATAATATAAATAATTATTTTTTAATCAAAGAAGAAAATATTAAATTTGAAAATAAGTTACATACATCAGAATTAATTATAAAAAATGAAACATTAAATGAATGTAAAGTTACAATGGAAGTTGGACGAATTAAAAAAGAAATATCAGAAAATGAAGAAGACGAATACTGCAATGATATTAATAGTGAAAGTGTTATAAGTGTTAAACATGAACCTCTTGTTGAAAATGATAAACAATTGTGTACAATTAATTACGAAAATATTAAACTTGAAAATGAATTACATACAGAAGTGATTATTAAAGATGAAATTTTAAATGAAAATTCTATTTTAGAATCACATGGGAATCATGCTGGAAGTACAAACCAATCATTTTTGTGTGATATTTGTAATAAAACATTTACCAAAAAACATCATTTAGTTAGACATAAACAGATTCATAGTGGTGAAAAACCATTTTCTTGTGATATTTGTAATAAAAGTTTTAGTGATCAACAAAATTTAGTTGCACATAAACGAATTCATAGTGGAGAAAAACCATTTTCGTGTGATTTTTGTAACAAAAGATTTACTCAACAAGGTGCTTTAGTTTCACATAAACGTATTCACAGTGGTGAAAAACCATTTTCATGTGATATTTGTAATAAAATATTTGCTCAAAGTAGTAATTTAAATAAACATAAACGAATTCATAGTGGTGAAAAACCGTTTCCATGTGATTTTTGTAATAAAACATTTACTCATCGAAGTTCTTTGATTGTACATATGCGGCTTCATAGTGGGGAAAAACCATTTTCATGTGATATGTGTAATAAAACATTTACTCAACGCACTTCTTTGATTGTACATAAACGGATTCATAGCGGAGAACAATCACTATTTTGTGATATTTGTTATAAAACATTTTCCACATCATCTAGTTTAGTTGCACATAAACGAATTCATAGCGGAGAAAAACCATTTGCATGTGAAGTTTGTAATAAAACATTTACTCAGAAAAGTAATTTAGTTACACATAAACGAATTCATAGTTGA
Protein Sequence: MANNSFNNINNYFLIKEENIKFENKLHTSELIIKNETLNECKVTMEVGRIKKEISENEEDEYCNDINSESVISVKHEPLVENDKQLCTINYENIKLENELHTEVIIKDEILNENSILESHGNHAGSTNQSFLCDICNKTFTKKHHLVRHKQIHSGEKPFSCDICNKSFSDQQNLVAHKRIHSGEKPFSCDFCNKRFTQQGALVSHKRIHSGEKPFSCDICNKIFAQSSNLNKHKRIHSGEKPFPCDFCNKTFTHRSSLIVHMRLHSGEKPFSCDMCNKTFTQRTSLIVHKRIHSGEQSLFCDICYKTFSTSSSLVAHKRIHSGEKPFACEVCNKTFTQKSNLVTHKRIHS

Sequence clustering based on sequence similarity using MMseqs2