Basic Information

Transcription Factor Domain

TF Family: zf-GAGA
Domain: zf-GAGA domain
PFAM: PF09237
TF Group: Zinc-Coordinating Group
Description: Members of this family bind to a 5'-GAGAG-3' DNA consensus binding site, and contain a Cys2-His2 zinc finger core as well as an N-terminal extension containing two highly basic regions. The zinc finger core binds in the DNA major groove and recognises the first three GAG bases of the consensus in a manner similar to that seen in other classical zinc finger-DNA complexes. The second basic region forms a helix that interacts in the major groove recognising the last G of the consensus, while the first basic region wraps around the DNA in the minor groove and recognises the A in the fourth position of the consensus sequence [1].
Hmmscan Out: # of c-Evalue i-Evalue score bias hmm coord from hmm coord to ali coord from ali coord to env coord from env coord to acc

1 6 0.37 2.5e+02 2.3 0.0 22 44 98 120 95 124 0.86

2 6 0.032 22 5.7 0.0 21 47 125 151 120 156 0.85

3 6 0.047 32 5.1 0.0 21 44 153 176 148 180 0.88

4 6 0.012 7.9 7.1 0.0 21 47 181 207 177 212 0.86

5 6 0.14 93 3.7 0.0 21 47 209 235 204 241 0.83

6 6 1.3 8.5e+02 0.6 0.0 21 43 237 259 230 263 0.74

#	of	c-Evalue	i-Evalue	score	hmm coord from	hmm coord to	ali coord from	ali coord to	env coord from	env coord to	acc
1	6	0.37	2.5e+02	2.3	22	44	98	120	95	124	0.86
2	6	0.032	22	5.7	21	47	125	151	120	156	0.85
3	6	0.047	32	5.1	21	44	153	176	148	180	0.88
4	6	0.012	7.9	7.1	21	47	181	207	177	212	0.86
5	6	0.14	93	3.7	21	47	209	235	204	241	0.83
6	6	1.3	8.5e+02	0.6	21	43	237	259	230	263	0.74

Coding Sequence: ATGGCAAATAATTATTTGTTTATTAATAAAGATAATATTAAAGTTGAAAAAGAATTACATACAGAACTAATTATTAAAAGTGAAATATTAGATGAAACTATTTTAATGGAAGGTGGACACATTACAAATGAAGAAGAAGGCAGCAATGATAGTGATAGTGTTGTGAGTGTAAAACATGAACCTGTTAGTGATGAAAATGATAAACAATTGTACACAATTAATTATGAAAACATTAAACTTGAACAAAAATTACATACAGAACTAATTATTAAAGATGAAACTGTTTTAGAAGAAAAATCATTTGTATGTGATGTTTGTAATAAAACATTTACTCAGAAAAGTAATTTAGTTAAACATAAACGTATTCACACCGGAGAAAAACCATTTTCATGTGATGTTTGTAATAAAACATTTACTCAGAAAGGTGAATTAGTTAGACATAAACGTATTCACAGCGGAGAGAAACCATTTTCATGTGATGTTTGTAATAAAACATTTACTCAGAAAGGTGAATTAGTTAGACATAAACGTATTCACACCGGAGAAAAACCATTTTCATGTGATGTTTGTAATAAAACATTTACTCAGAAAAGTAATTTAGTTAAACATAAACGTATTCACACCGGAGAGAAACCATTTTCATGCGATGTTTGTAATAAAACATTTACTCAGAAAGTTGAATTAGTTAAACATAAACGTATTCACACCGAAGAGAAACCATTTTCATGTGATGTTTGTAATAAAACATTTAATGAGAAAGGTGAATTAGTTAAACATAAACGTATTCACAATCGATAA
Protein Sequence: MANNYLFINKDNIKVEKELHTELIIKSEILDETILMEGGHITNEEEGSNDSDSVVSVKHEPVSDENDKQLYTINYENIKLEQKLHTELIIKDETVLEEKSFVCDVCNKTFTQKSNLVKHKRIHTGEKPFSCDVCNKTFTQKGELVRHKRIHSGEKPFSCDVCNKTFTQKGELVRHKRIHTGEKPFSCDVCNKTFTQKSNLVKHKRIHTGEKPFSCDVCNKTFTQKVELVKHKRIHTEEKPFSCDVCNKTFNEKGELVKHKRIHNR

Sequence clustering based on sequence similarity using MMseqs2