Basic Information

Gene Symbol
PRDM11
Assembly
GCA_905475395.1
Location
FR997755.1:36978457-36993003[-]

Transcription Factor Domain

TF Family
zf-C2H2
Domain
zf-C2H2 domain
PFAM
PF00096
TF Group
Zinc-Coordinating Group
Description
The C2H2 zinc finger is the classical zinc finger domain. The two conserved cysteines and histidines co-ordinate a zinc ion. The following pattern describes the zinc finger. #-X-C-X(1-5)-C-X3-#-X5-#-X2-H-X(3-6)-[H/C] Where X can be any amino acid, and numbers in brackets indicate the number of residues. The positions marked # are those that are important for the stable fold of the zinc finger. The final position can be either his or cys. The C2H2 zinc finger is composed of two short beta strands followed by an alpha helix. The amino terminal part of the helix binds the major groove in DNA binding zinc fingers. The accepted consensus binding sequence for Sp1 is usually defined by the asymmetric hexanucleotide core GGGCGG but this sequence does not include, among others, the GAG (=CTC) repeat that constitutes a high-affinity site for Sp1 binding to the wt1 promoter [1].
Hmmscan Out
# of c-Evalue i-Evalue score bias hmm coord from hmm coord to ali coord from ali coord to env coord from env coord to acc
1 12 4.3 93 4.2 2.5 1 23 263 286 263 286 0.97
2 12 0.00052 0.011 16.5 1.2 1 23 531 553 531 553 0.98
3 12 8.3e-05 0.0018 19.0 1.9 1 23 587 609 587 609 0.98
4 12 0.00075 0.016 16.0 0.9 2 20 615 633 614 635 0.94
5 12 0.036 0.77 10.7 2.5 1 23 645 668 645 668 0.97
6 12 0.00015 0.0033 18.2 0.6 2 23 705 726 704 726 0.95
7 12 1.5 32 5.6 4.7 3 23 733 753 731 753 0.96
8 12 4.9e-05 0.0011 19.7 3.4 1 23 758 780 758 780 0.97
9 12 0.00066 0.014 16.2 5.2 1 23 787 810 787 810 0.95
10 12 0.0012 0.025 15.4 0.3 1 23 817 839 817 839 0.97
11 12 0.0029 0.062 14.2 1.6 2 23 852 874 851 874 0.94
12 12 0.041 0.89 10.5 2.1 1 23 879 902 879 902 0.96

Sequence Information

Coding Sequence
ATGCCAACAATTATTAATTTGGAAAATATTGAAAATGATTTAGGTGCACAAATAAATAATAGTATTGAATATATAAATAAAGGTTGTACATTATGTGGAGGAGATAGTCATAAAATTGAAGAATGTAATATATTAACGAATATCAAGCATATTCATGATAAAAAAATACCAACTAGAGCACGGCTCACATTACCTAGTGAGCTACGAGTCGAAACAATGTCTGATGGAACGTGTAATGTTGTTGCACAAGTGCCATTACCGAAAGGAACAAGATTTGGTCCTTTCGAAGGTAAAAAGATACAAATATTACATCCATTAATTACATTTCCTATAAAATTATTTAAAATCGATGAAAATGACATCGAATATTATTTCGATCCAAGCAACGAGGAAATTGGAAACTGGATGTGTTTTGTTGCAGCTGCAAATGATATTTTGGAACAAAATTTAATTTGTTATCAAATGAAAAATAATATATATTATTCAGCAATACGCGATATAAAAGTAGGAGAATATTTAAAAGTATGGTATGCAGCTTATTATGCGGAAAAAATGGGCACAGCAGTATTAAAACGTGTTGAATCAGATCCACAAAATTATGCTGATGATATTAAAGTCGAAAAACTTGTAAATCAGAAAGTAGCTGAAACATTACCAGCGGAGAATTTAGGTGCAACAACTGATACAAGCATATGGGTTTGTCGATTTTGTAAAACTACAATAAAAAATATTGTATTATTTTCAACACATTTACAGCAACATTATAAAGATCTTGCTGCGAAAACGTTTACGTGTGCAATATGTTATAAACATTGTTTATCGGAAAAGGCATTATTAAGTCATCAAATAACAATACACAATTTAAATGTCGCACAACACAAATTACCATTAATCCAAAAACAAAATGAAATTACAACATCAATTGTTGATACAACATCATCCTCATCGTCAACAAACAATAATTCAATACAGCATTTCTTCAACAATAAAAAAGATGATACAACAGTTGTTGAAGCAACCACTACAACCGTATCGACACCAACCCCAACATCAACAAATCAGCAATTGGATACAAACAATATATTTACAAAAATCAATGTATATGATACCGATTTAGATTTTAGTACAAAAACAATTGTTAATGACAGTTTAGTAGGTGGTCAAACACAAGACCAAATTGATCAAAATACTTCGCTGTTGGATCAATCAACAAATGCGTTGCTGGTTGATAACATTACGTTAAATTATAACCATCACGATTTAAATAATGTTATGCTAACGAAAATCAGTGAATTAAATGAACATTTGAAGTTTGATATCAAAGATACCACAGTATCTGGTAGTGATTTAAACGATAGTTTGAATACGGATTCGTTACATGATATCTTGTGTGAGGATGATTCGAAGGCAAGCAAAATTGCACAAGAGAAAAGTATTGCTGATTTTAGTTTAGATTTTGTTGAGAGTAATGGTCTAAATTTAAACACACCGTCTACCTTAAGTACAAATGACACGAATACAACTGATACAAATAGTAATACGAATATACCGACAAATCAAGATTTGCCACCTCCAGAATCCGGACCACCATATTATTGTGATATATGTCGAAAAGAATTTCAAAATATTGAATATTTAATACGTCACTTGAAAAAACATTCTGGTGAATTTACTTGTATCGATTGTTTTGCGGTATTTGGACGACGAGAAAATTTTTTAAATCATTCATGTAAATGGGATTCAAAGAAGAAAAACACATTTGAATGTATGTACTGCTCAAAAGTATTTAGTGAACAAAAATATTTAAATCGACATGTGCAACGCCACAATAAACAACGTAAAACATGCCCTAAATGTGGTACAGTATTTGAAAATGAAAGTGACTTGGAACATCATGTATGCGATACAACTAAACCGATAGTGGAGAAGAAATTTGAATGTGATATATGTAAAAATAGATATATTAAGAATTCATATTTACGTGGACACATACTAAAATGTCATAAAAAACCAGCTGAACAAGCTGCAGCGGCTGCTGCAAATAAAACTCTAACCGATAATAATTCAACTACTGCAACCGATTCATCTTCATCATCATCAACTTCACAATGTATTTGTTACATGTGCGGGGAATCGTTTAGTAATGCGGCAACCTTAAAATCACATTTATTAATACATCAACCGAAAAAATATGGTTGTGATGTTTGTGATAAAAAATTCCATCGTTCTGAAACTTGTGAACAACATAAATTAACACATACAAATGCAACATTTGACTGTAAAACATGTTCTAAAATGTTTAAATCTCAAAAATCGTTGAAAAAACATCAATTAATACATAACGACGCATCCGAATGTCATAAATGTGAATTTTGTAATCGTATATTTATACAAAAACATAATTTGGAGAAGCATATAAATTTTCAACATTCAGTTGATCAACCGAAATTTCCATGTGATTTATGTACAAACGTCTTTACATCTGCGAATAATTTAAAAGATCATAAAGCTACACATAATTTAACTGATAGTCTGAACAGCAGTAAACAACTTTCATGTGAATATTGTAAAAAGAATTTTACAAAGACAAATTTATTAAAAGCCCATTATGTGACAACACATTTAAACCGTATGTTCTCCTGTCCATATTGTACAACAATTGTAAAACATCGTGCATCAATACGTCGCCATTTAAGTAAAAGTCATCGTGAGAAACGTGGCGAATGGGATAATTCTGATTTTATTGGTAAATTAGTATCACAAAATAAAAAACCACCGGATGAATTAGAACATGACAATTCAACAACATCAACCATTGATATGAACACATCAACACAACATTTAGTTCCTATTGAACCAGTGACATCGTCAACAATGAATCTAACAGATAATCTAACAAATAATAGTACAACAAATACAAATGATTCAACAATCTTACTTCAAAATTCATCCACCGATAATGAAATGGATACAAATGATATTAATCAAAATCATACGTTAATTGTTGAACAACAACAACAACAACAAGAACAACACATGGTACAACAGAATCAACAGCAACAACATTTATTACCTAAAATGTATAATACGATGTCACAAGTGGTTGATTCAACACATCAACTCTTTACAACAACAAATAATGATCAACTAGAATTTCAAAATATTATTTATTTAAAAAATAATCATGATGTTGATCTAGATTTGGAGAAGATCACTGAATATAGTAATTTAGATTCAGCAACAGCTAAATTATCACAATTCTCAGATTTATCATCAACATCATCACAAATACAAGTCACATCACATAATTCACATCAATTACATCAATCAAATAACACAGATAATTTACCAAAATTCACCCGTATTGATCGTTCAAATGATTTTGATATGATGGACATACAGTCATTAATATCAACCGATAGTGGCATGATAGAATTTCCAAATGAGTTGGTCGAACGTACCGATACAACACCTCAATTTACGAATAATATGAATTTGCAGTTACATAATGATCGTGAAGTCACATTAGGTAAGAACGCCTTTATCTTAGATGATGGAACAATTGTGGAACCCCAAGAAGCGGGTAATTTAATGTTTTATGTACTTAACCAATCATAA
Protein Sequence
MPTIINLENIENDLGAQINNSIEYINKGCTLCGGDSHKIEECNILTNIKHIHDKKIPTRARLTLPSELRVETMSDGTCNVVAQVPLPKGTRFGPFEGKKIQILHPLITFPIKLFKIDENDIEYYFDPSNEEIGNWMCFVAAANDILEQNLICYQMKNNIYYSAIRDIKVGEYLKVWYAAYYAEKMGTAVLKRVESDPQNYADDIKVEKLVNQKVAETLPAENLGATTDTSIWVCRFCKTTIKNIVLFSTHLQQHYKDLAAKTFTCAICYKHCLSEKALLSHQITIHNLNVAQHKLPLIQKQNEITTSIVDTTSSSSSTNNNSIQHFFNNKKDDTTVVEATTTTVSTPTPTSTNQQLDTNNIFTKINVYDTDLDFSTKTIVNDSLVGGQTQDQIDQNTSLLDQSTNALLVDNITLNYNHHDLNNVMLTKISELNEHLKFDIKDTTVSGSDLNDSLNTDSLHDILCEDDSKASKIAQEKSIADFSLDFVESNGLNLNTPSTLSTNDTNTTDTNSNTNIPTNQDLPPPESGPPYYCDICRKEFQNIEYLIRHLKKHSGEFTCIDCFAVFGRRENFLNHSCKWDSKKKNTFECMYCSKVFSEQKYLNRHVQRHNKQRKTCPKCGTVFENESDLEHHVCDTTKPIVEKKFECDICKNRYIKNSYLRGHILKCHKKPAEQAAAAAANKTLTDNNSTTATDSSSSSSTSQCICYMCGESFSNAATLKSHLLIHQPKKYGCDVCDKKFHRSETCEQHKLTHTNATFDCKTCSKMFKSQKSLKKHQLIHNDASECHKCEFCNRIFIQKHNLEKHINFQHSVDQPKFPCDLCTNVFTSANNLKDHKATHNLTDSLNSSKQLSCEYCKKNFTKTNLLKAHYVTTHLNRMFSCPYCTTIVKHRASIRRHLSKSHREKRGEWDNSDFIGKLVSQNKKPPDELEHDNSTTSTIDMNTSTQHLVPIEPVTSSTMNLTDNLTNNSTTNTNDSTILLQNSSTDNEMDTNDINQNHTLIVEQQQQQQEQHMVQQNQQQQHLLPKMYNTMSQVVDSTHQLFTTTNNDQLEFQNIIYLKNNHDVDLDLEKITEYSNLDSATAKLSQFSDLSSTSSQIQVTSHNSHQLHQSNNTDNLPKFTRIDRSNDFDMMDIQSLISTDSGMIEFPNELVERTDTTPQFTNNMNLQLHNDREVTLGKNAFILDDGTIVEPQEAGNLMFYVLNQS

Similar Transcription Factors

Sequence clustering based on sequence similarity using MMseqs2

100% Identity
iTF_01061239;
90% Identity
iTF_01061239;
80% Identity
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