Basic Information

Transcription Factor Domain

TF Family: zf-GAGA
Domain: zf-GAGA domain
PFAM: PF09237
TF Group: Zinc-Coordinating Group
Description: Members of this family bind to a 5'-GAGAG-3' DNA consensus binding site, and contain a Cys2-His2 zinc finger core as well as an N-terminal extension containing two highly basic regions. The zinc finger core binds in the DNA major groove and recognises the first three GAG bases of the consensus in a manner similar to that seen in other classical zinc finger-DNA complexes. The second basic region forms a helix that interacts in the major groove recognising the last G of the consensus, while the first basic region wraps around the DNA in the minor groove and recognises the A in the fourth position of the consensus sequence [1].
Hmmscan Out: # of c-Evalue i-Evalue score bias hmm coord from hmm coord to ali coord from ali coord to env coord from env coord to acc

1 5 8.3e-05 0.73 10.0 0.1 16 50 41 75 32 79 0.85

2 5 0.00014 1.3 9.2 0.2 23 45 76 98 72 101 0.89

3 5 0.0012 11 6.2 0.2 20 44 101 125 97 134 0.85

4 5 0.015 1.4e+02 2.7 0.1 21 44 130 153 127 161 0.86

5 5 0.00044 3.9 7.7 0.0 23 45 160 182 154 188 0.91

#	of	c-Evalue	i-Evalue	score	bias	hmm coord from	hmm coord to	ali coord from	ali coord to	env coord from	env coord to	acc
1	5	8.3e-05	0.73	10.0	0.1	16	50	41	75	32	79	0.85
2	5	0.00014	1.3	9.2	0.2	23	45	76	98	72	101	0.89
3	5	0.0012	11	6.2	0.2	20	44	101	125	97	134	0.85
4	5	0.015	1.4e+02	2.7	0.1	21	44	130	153	127	161	0.86
5	5	0.00044	3.9	7.7	0.0	23	45	160	182	154	188	0.91

Coding Sequence: ATGGCCTCGAGAGAGGAATTTGAGGAAGCTATGCCACTGAATGGTGTGGTGGCCATGTATACTTGCAAACGCTGTAACAAGATATTTCCCTGTAAACGTGATCAACTTTTGCACAAAAAAGAAGTTCACTCCCAAACAAAATCTTCATATGAATGTAAAATCTGTACAAAATACTTTTGCAACAGTGGCAATTTGGAACGTCACATGAAGGTCCACAATGATGTACGTCCCTTTGTTTGCCGCATTTGCGGAAAGGCATTTGCCCAATCTGTTAATTTAAATCGTCATTATTCTGTACATAATGGCGAACGTCCCTATCCATGTACGTTTTGTACAAAAACGTTTACACAACAATCGAACATGCAACGCCATCAATTGACACACACCGGAGAGAAACCTTTTCGCTGTAAACGTTGCGGGCGTTATTTTTCTCAGCGCGTTAACCTTAAAAAGCATATTATGGGCCATTTGAATACCAAACCATACACGTGCAAAATCTGTCAAAAGTCATTTATACAATTGGGTAATTTCAAGAAACATTTAAATTCTCATGTCAAAGAAGGTATACAAATGGATATGAAGGCGATTGTGGCCGAGGCTCAGGCTATGGCTAAACAAAGTTTGGAAATGGCCGATGATCAGCCAGTAGGTTTCGAATGTGCTGTTTGTCGTTTGATTTTCAATAATTTCACCGACTTTGAAATGCATGAAAGTGAGTGCAATGAAAATGCACAAGCGGCCATGGAGCAAAAATACAATCCCGATGAACAGCTACAAGAAGTAGTTGTTGAAGAAGTTGAAGATCATGTAGAAGAGCAGATAATTACCCATGATGGTATTGTAACCAGTGGAGACTTTGGTAGTTATGCACCTTTAAAATTTAGTGTTTCACAATTGGATACACATGAAATAATTATTGAAACCAGTCGATAA
Protein Sequence: MASREEFEEAMPLNGVVAMYTCKRCNKIFPCKRDQLLHKKEVHSQTKSSYECKICTKYFCNSGNLERHMKVHNDVRPFVCRICGKAFAQSVNLNRHYSVHNGERPYPCTFCTKTFTQQSNMQRHQLTHTGEKPFRCKRCGRYFSQRVNLKKHIMGHLNTKPYTCKICQKSFIQLGNFKKHLNSHVKEGIQMDMKAIVAEAQAMAKQSLEMADDQPVGFECAVCRLIFNNFTDFEMHESECNENAQAAMEQKYNPDEQLQEVVVEEVEDHVEEQIITHDGIVTSGDFGSYAPLKFSVSQLDTHEIIIETSR

Sequence clustering based on sequence similarity using MMseqs2