Basic Information

Insect: Chrysolina americana
Gene Symbol: Hr39
Assembly: GCA_958502065.1
Location: OY293414.1:24018534-24047605[+]

Transcription Factor Domain

TF Family: SF-like
Domain: zf-C4|SF-like
PFAM: AnimalTFDB
TF Group: Zinc-Coordinating Group
Description: The ligand binding domain of nuclear receptor steroidogenic factor 1 (SF-1): SF-1, a member of the nuclear hormone receptor superfamily, is an essential regulator of endocrine development and function and is considered a master regulator of reproduction. Most nuclear receptors function as homodimer or heterodimers, however SF-1 binds to its target genes as a monomer, recognizing the variations of the DNA sequence motif, T/CCA AGGTCA. SF-1 functions cooperatively with other transcription factors to modulate gene expression. Phospholipids have been determined as potential ligands of SF-1. Like other members of the nuclear receptor (NR) superfamily of ligand-activated transcription factors, SF-1 has a central well conserved DNA binding domain (DBD), a variable N-terminal domain, a flexible hinge and a C-terminal ligand binding domain (LBD). [1, 8, 3, 11, 6, 5, 12, 10, 9, 2, 4, 7]
Hmmscan Out: # of c-Evalue i-Evalue score bias hmm coord from hmm coord to ali coord from ali coord to env coord from env coord to acc

1 3 3.9e-08 0.00071 21.1 0.0 1 25 339 363 339 379 0.86

2 3 0.0096 1.7e+02 3.3 0.0 77 117 390 430 362 463 0.74

3 3 3.2e-73 5.8e-69 235.5 0.1 205 408 470 668 446 668 0.96

#	of	c-Evalue	i-Evalue	score	bias	hmm coord from	hmm coord to	ali coord from	ali coord to	env coord from	env coord to	acc
1	3	3.9e-08	0.00071	21.1	0.0	1	25	339	363	339	379	0.86
2	3	0.0096	1.7e+02	3.3	0.0	77	117	390	430	362	463	0.74
3	3	3.2e-73	5.8e-69	235.5	0.1	205	408	470	668	446	668	0.96

Sequence Information

Coding Sequence: ATGGCTTTATGCCAGAGTCATCAGACCTATGATAACATATGGGtcggtggtatggtggccaaagacaAAGCAGGCAGGGGTAGTACGACGGCTGGGAGGACTGCAAAGACAAGCATGTCTGAGTGCTACCGGAGCCATGAGAACTACTCCAACAGCCGCACTAGAAGTCTTGCTCAACCTGCCACCACTATACACATACACATTCAAGGCGAAGCCAGGTCGGTCACGAGCAGATTACTTAGAGGTCAAACGCCCATAAGCAAGATGCACGGAAGAGACTACAACAAGCTAtatgaagagttggaaaacgaCCTTATCATGAGAATGCCATCAGATGGTATACTCCCGAGATATAGCTTTGACAAATCTTTCAAGATAAGCATAACGAACAGGGGTGCGTGGAAAAAGGGAGCTCCCATCAATGCAGAAATCGCCGTCTACACTGATGGCTCAAAAACCgatgaaggttcaggagccgGCATATACGGAGCCAAGCCGAAGATACAAATCTCACTGAGCTTAGGCAAATATGCGACGATATTCCAAGCGGAAATCGTCGCAATGCATCATTTCGCGCAGGAGTTAATAAGGCAAGAGTTCTCAGGAAAAaccattGGTAGACATATACATAGTATCCACAGTAGCCCTCTTCATCATAACCTACTATATCGAAGTCTCCAAGATGAGAATACACAATATGCTGCCGAACAAGAAGTTCTTGAGGAAACTGAAGATAAAACGGGTCTCTTCCACACATCACTGCCTGCTCAACCTGGAATTTCTAGGCAACAGCTAATAAACAGCCCGTGTCCCATTTGTGGAGACAAAATATCCGGATTCCACTACGGCATTTTTAGTTGTGAGTCGTGTAAAGGATTTTTCAAAAGGACTGTTCAAAATAGAAAGAATTATGTGTGTCTCAGAGGAGCTCAGTGTCCTGTTACGGTTGCCACAAGAAAAAAGTGCCCGGCTTGTCGTTTCGAAAAATGTCTTCAGTGTGGGATGAAACTAGAAGcaATTCGTGAAGACAGAACTCGTGGGGGTAGGTCAACATATCAATGTTCATATTCTTTGCCGCCATCCTTAACCAACCACGCAGAACTCAGGGCGAGTTCGACTGATTTGAGGCAAGGCATGGGTGATGGCCATCCAGGGTTTACTGTAAAACAAGAACCTCCGGATTCCAGTAATCCACATCATAAGAGGACTACATATCCAGGTTCCAGAGGTGTCCCACCATTATTGCAGGAAATAATGGATGTGGAGCACCTATGGCACTACAACGAAATGGAACTAAATAAGCTCAGCACCGAGGGCCACCTGGGCAAAGAGGGATCTAGTGGAGCGGTACACAATCTTTCCACCCATCCACTCTTGGCTGGTACAGCATTGGCTGGATCAACAGATACAAATCCGGATTTTGTGTCGAATCTCTGCAATATTGCTGATCATAGACTTTACAAAATTGTGAAGTGGTGCAAAAGTCTTccattgtttaaaaatatttcgattgaCGACCAGATTTGTTTGCTAATCAATTCCTGGTGTGAGCTGCTGCTATTTTCATGTTGCTTTCGATCAATGTCTACCCCAGGCGAGATAAGAGTCTCGCTTGGAAAAAGTATAACTCTCGTGCAAGCTAGAGAAATGGGGTTGCAGCCTTGTATAGAGAGAATGTTGAATTTTACCGAACAACTAAGAAGGTTGCGGGTGGATCAATatgagtacatagcaatgaaagtcattgttctTCTTACATCTGACACTTCCGAATTGAGAGAGGCAGAGAAAGTGAGAGTCTCACAAGAAAAAGCTTTAAAAGCTCTACAGGATTACACGTTGTCACATTATCCTGAGAGTCCTTCCAAATTTGGAGAATTGCTTCTAAGGATTCCTGAGTTGCAACGAACTTGCCAAgtGGGAAAAGAAATGTTAACAATCAAATCAAAAGATGGCGAAGGACCCAGCTTCAACCTCCTAATGGAACTCCTGAGGGGAGACCACTGA
Protein Sequence: MALCQSHQTYDNIWVGGMVAKDKAGRGSTTAGRTAKTSMSECYRSHENYSNSRTRSLAQPATTIHIHIQGEARSVTSRLLRGQTPISKMHGRDYNKLYEELENDLIMRMPSDGILPRYSFDKSFKISITNRGAWKKGAPINAEIAVYTDGSKTDEGSGAGIYGAKPKIQISLSLGKYATIFQAEIVAMHHFAQELIRQEFSGKTIGRHIHSIHSSPLHHNLLYRSLQDENTQYAAEQEVLEETEDKTGLFHTSLPAQPGISRQQLINSPCPICGDKISGFHYGIFSCESCKGFFKRTVQNRKNYVCLRGAQCPVTVATRKKCPACRFEKCLQCGMKLEAIREDRTRGGRSTYQCSYSLPPSLTNHAELRASSTDLRQGMGDGHPGFTVKQEPPDSSNPHHKRTTYPGSRGVPPLLQEIMDVEHLWHYNEMELNKLSTEGHLGKEGSSGAVHNLSTHPLLAGTALAGSTDTNPDFVSNLCNIADHRLYKIVKWCKSLPLFKNISIDDQICLLINSWCELLLFSCCFRSMSTPGEIRVSLGKSITLVQAREMGLQPCIERMLNFTEQLRRLRVDQYEYIAMKVIVLLTSDTSELREAEKVRVSQEKALKALQDYTLSHYPESPSKFGELLLRIPELQRTCQVGKEMLTIKSKDGEGPSFNLLMELLRGDH

Similar Transcription Factors

Sequence clustering based on sequence similarity using MMseqs2

100% Identity: iTF_00328315;
90% Identity: iTF_00328315;
80% Identity: iTF_00328315;