Cnem021117.1


Basic Information
Transcription Factor Domain
Sequence Information
Similer Transcription Factors

Basic Information

Insect
Choreutis nemorana
Gene Symbol
egg
Assembly
GCA_949316135.1
Location
OX438625.1:3498298-3520635[+]

Transcription Factor Domain

TF Family
MBD
Domain
MBD domain
PFAM
PF01429
TF Group
Unclassified Structure
Description
The Methyl-CpG binding domain (MBD) binds to DNA that contains one or more symmetrically methylated CpGs [2]. DNA methylation in animals is associated with alterations in chromatin structure and silencing of gene expression. MBD has negligible non-specific affinity for DNA. In vitro foot-printing with MeCP2 showed the MBD can protect a 12 nucleotide region surrounding a methyl CpG pair [2]. MBDs are found in several Methyl-CpG binding proteins and also DNA demethylase [1].
Hmmscan Out
# of c-Evalue i-Evalue score bias hmm coord from hmm coord to ali coord from ali coord to env coord from env coord to acc
1 2 2.3 6e+03 -2.7 0.0 29 38 568 577 542 578 0.68
2 2 2.1e-13 5.6e-10 39.1 0.0 4 74 609 672 606 675 0.88

Sequence Information

Coding Sequence
ATGACAGCGGTGGAACAGGAGTCGTCCCGCGGCTGCAGCGGCTGCATCAACTACAAGTGCATGAGCGCGGGCGACACGCCGCTGCTGTCCGCGAGCGCCGCCGCGCTGGCGTACTACAACGCCAAGCGACGGCGCCGCCCGCATGTGTGCGCGGAATGCCATCGAGTCGTCACTGACAGGACCCAGGCTCTAGTTGAAGGCGTAAAGAATATGACTCCACTCCTCGATCTCGAGATGTGCAGGAACATGGAGGAGCTGGTCGAGATTTCGGATTCCGATTCAGATGATGACTGCGAAGTCAACGTCACGGATAAAATGACAATCGGAGAATCCACCGCTGAATTCCTAAAGGAAAACCTAGTTGAAATAATAAACGAAACATGGTGTAAATACGACATGGACGCAAGACTGTTGGAGACTCAGGAGTCATTGGAATGTCAGATCAATGGTTTGGAGAttGACTGCAAAGAGATCGACACGATGCTGAACGAATGTCAAGTGGCGACTGACAAGCTGAGGAAGGATTTATACGCAACGTTTGAACAGGAGAAGAAAGAAACACCCGGGATACATATATACGATACCGGTGTCACTTTTTCCGTATCTTCAGATGCTACTGATCAAcTGCGTTTCTCGAAAAGGAAATCCTCCACCGGTATCGAACCGCCTGCCAAACGGACCGCGTCATCTGTCAGCGGGTCCCACAATGACGGTGACGGACATCAGGATAACAGAGGTGATGATGATAACGTCGACGTATGCGTGGTGAAGCTGTCCGGGGAATCCGCCCCCGCGGGGCTGCCACCTCCGGGCGAAGCCCCGCGCCCACCACTAAGACCCGGCGTCAGTGTATACGCCATGAGGAACGCGTTCGGCGCGTGGCTTCGAGCTACTGTATTGGAGGTGCAGGCTAAAGGGAACAATGCAACGTACCCTACGTTCACGGTGTGCAAGGTAAAATTCGAGCATAAATCCAAAAACAAAGTGCTGCCGGCTCGATGCCTCGCTTACGAAGTCGCCTGCAACGTCAGGTTGACTATCGGTACTCGGGTGATAGCTCTGTTCAAAGATGACTCGCAGACACACAAAAAGGAGACTTACTACTCTGGAATAGTGGCCGAAATACCTAATCCAGTTAATAACTACAGgtaTCTCGTTTTCTTCGACGATGGATACGCGCAGTACGTTCAGCATAAAGACACGCGGCTCGTTTGCGAATGTTCACCTTTAGTTTGGGAGGAGGTGCATCCGTTTTCGCGTCAATTCGTTCGCGAATATTTGATAGCGTATCCCGAGAGACCGATGGTGAGACTACACGCCAACCAAACCATCAAGACAGAATGGAACGGTAAATGGTGGGTGTCGAAAGTGATGAAAGTGGACGCATCCCTCGTGCAAGTCCACTTTGAAGAGGACGACAGGTCCGAATGGATATACAGGGGCTCTACGAGATTAGCTCCACTATATTTAGAGCTGAAAGCAGCGGAGAGACACCGAGCCAGACCGTTGCCTAGATCTACTAATAATCAGAAACAGCTAAACATGCCGTACGTTGAATACACACGGACAGACGAACAGGGGAACAGCAATAAGGGGGCTCAAAACgagGAGTTGCGTCGTCAACAACAACGCGCCGTCGCGAAGAAATCGACAGCGCAACCCGCGCCGCCGCAACAACAAGTACTACCGAACTCCGATAGCATTACATCTAGAGTCGTTTACTACACTCCAAAGAACGCAGTCCGCCCTCACAAGATGGTGTCGCACACATGCGGGCCGCGCTGCGTTCGATCCGATGTGCTCAAACTGAAAGAACTACGCACTTACAACCCGCTTGCGAAACCACTGCTCAGTGGCTGGGAGAGaCAACTGGTGAGATTCAAAGGCCAAAGAGAGGTGATGTACCGGGCTCCTTGCGGCCGGAGACTGAAAAATATGAAGGAATTACATTATTATCTAAACCTGATCCAGTCCGAGATGTCAGTTGATTTGTTCGACTTCGGTCCGAACACTCACTGCTTAGCCGAGTTCGTGTTGAACAAGTGCCTCGTCAGCAAAAAGgaCCTCTCCCACGGCAAGGAGCGTGTGCCGGTGCCGTGCGTAAATTACTACGACGATTCATTACCTGAGTTCTGTTCTTACAACACTGAACGAACGCCAACAGCTGGCGTGCCTTTGAACCTCGACCCTGAGTTCCTGTGCGGCTGCGATTGTACTGATGACTGCCAGGACAGAAGTAAATGTGCTTGCTGGGCTCTGACGTTCGAGGGTGCTCGTACTATAGGGCTGGATGATAACGTTGGCTACGTGTACAAGAGGTTGCCAGAGCCATTGCCGTCTGGAATATATGAGTGTAACTCTAGatGTAAATGCAAGCAGACATGTTTGAATAGAGTAGCGCAGCATCCTCTGCAATTAAAACTTCagGTATTCAAGACATTGAATCGCGGTTGGGGTATACGCGCCTTAAACGACGTACCAAAAGGTGCGTTCCTATGTGTGTACGCTGGGAACCTGCTGACAGATGCCACCGCCAATCTGGACGGTTTGAACGAAGGCGACGAGTATCTAGCTGAACTGGACTACATCGAGGTCGTGGAGCAGATGAAGGAGGGCTTCGAGGAAGATATACCTGATGCTGACAAGGAACTGGATAAGGAAAGTAAATCCCGTAAGGCGGACGAGAGCGATGATGGAGATGATGATGAGCCGTCATCAACTGATGATGAGAAAGATGACAAAGGTGACAAGTCGGACGGCGACTTCAAACCTGACAGATACGTGGGGGTACAGGATATGAGCAGGAAGACTTTAAGGAAAAGAGAGAAGAAGAAAGAGAAGGAAAGGAAGTCTAAAGCGGAAGATGACTGCATCACCATCAGCGATGATGAAGAAttgaGAGAACCATCTCGGTTCATGGCGGACGCAGAAATGAAGTCAGACACATACATATCGAAATATAAgtcTGTCCGTACGTTGTTCGGCAAAGATGAAGCATGCTACATCATGGACGCAAAAGTACAAGGGAATATAGGgagatatttaaatCACTCCTGCTCTCCGAACGTGTTCGTACAGAACGTCTTTGTAGACAGCCACGATCCGCGCTTTCCATGGGTGGCTTTCTTCGCATCATGTCATATCAAAGCAGGCACCGAGCTGACGTGGAACTACAATTATGATGTAGGCTCGGTACCTGGGAAGGTTTTATACTGCTATTGCGGTGCTCCGAACTGCAGGCGGAGGCTTTTGTAA
Protein Sequence
MTAVEQESSRGCSGCINYKCMSAGDTPLLSASAAALAYYNAKRRRRPHVCAECHRVVTDRTQALVEGVKNMTPLLDLEMCRNMEELVEISDSDSDDDCEVNVTDKMTIGESTAEFLKENLVEIINETWCKYDMDARLLETQESLECQINGLEIDCKEIDTMLNECQVATDKLRKDLYATFEQEKKETPGIHIYDTGVTFSVSSDATDQLRFSKRKSSTGIEPPAKRTASSVSGSHNDGDGHQDNRGDDDNVDVCVVKLSGESAPAGLPPPGEAPRPPLRPGVSVYAMRNAFGAWLRATVLEVQAKGNNATYPTFTVCKVKFEHKSKNKVLPARCLAYEVACNVRLTIGTRVIALFKDDSQTHKKETYYSGIVAEIPNPVNNYRYLVFFDDGYAQYVQHKDTRLVCECSPLVWEEVHPFSRQFVREYLIAYPERPMVRLHANQTIKTEWNGKWWVSKVMKVDASLVQVHFEEDDRSEWIYRGSTRLAPLYLELKAAERHRARPLPRSTNNQKQLNMPYVEYTRTDEQGNSNKGAQNEELRRQQQRAVAKKSTAQPAPPQQQVLPNSDSITSRVVYYTPKNAVRPHKMVSHTCGPRCVRSDVLKLKELRTYNPLAKPLLSGWERQLVRFKGQREVMYRAPCGRRLKNMKELHYYLNLIQSEMSVDLFDFGPNTHCLAEFVLNKCLVSKKDLSHGKERVPVPCVNYYDDSLPEFCSYNTERTPTAGVPLNLDPEFLCGCDCTDDCQDRSKCACWALTFEGARTIGLDDNVGYVYKRLPEPLPSGIYECNSRCKCKQTCLNRVAQHPLQLKLQVFKTLNRGWGIRALNDVPKGAFLCVYAGNLLTDATANLDGLNEGDEYLAELDYIEVVEQMKEGFEEDIPDADKELDKESKSRKADESDDGDDDEPSSTDDEKDDKGDKSDGDFKPDRYVGVQDMSRKTLRKREKKKEKERKSKAEDDCITISDDEELREPSRFMADAEMKSDTYISKYKSVRTLFGKDEACYIMDAKVQGNIGRYLNHSCSPNVFVQNVFVDSHDPRFPWVAFFASCHIKAGTELTWNYNYDVGSVPGKVLYCYCGAPNCRRRLL

Similar Transcription Factors

Sequence clustering based on sequence similarity using MMseqs2

100% Identity
-
90% Identity
-
80% Identity
-