Basic Information

Gene Symbol
-
Assembly
GCA_963691955.1
Location
OY829897.1:17238589-17247571[+]

Transcription Factor Domain

TF Family
zf-C2H2
Domain
zf-C2H2 domain
PFAM
PF00096
TF Group
Zinc-Coordinating Group
Description
The C2H2 zinc finger is the classical zinc finger domain. The two conserved cysteines and histidines co-ordinate a zinc ion. The following pattern describes the zinc finger. #-X-C-X(1-5)-C-X3-#-X5-#-X2-H-X(3-6)-[H/C] Where X can be any amino acid, and numbers in brackets indicate the number of residues. The positions marked # are those that are important for the stable fold of the zinc finger. The final position can be either his or cys. The C2H2 zinc finger is composed of two short beta strands followed by an alpha helix. The amino terminal part of the helix binds the major groove in DNA binding zinc fingers. The accepted consensus binding sequence for Sp1 is usually defined by the asymmetric hexanucleotide core GGGCGG but this sequence does not include, among others, the GAG (=CTC) repeat that constitutes a high-affinity site for Sp1 binding to the wt1 promoter [1].
Hmmscan Out
# of c-Evalue i-Evalue score bias hmm coord from hmm coord to ali coord from ali coord to env coord from env coord to acc
1 24 0.0045 0.31 12.0 1.6 3 23 650 671 649 671 0.96
2 24 7.1 4.9e+02 1.9 0.7 4 21 1035 1052 1033 1053 0.87
3 24 0.07 4.8 8.2 0.6 1 21 1061 1081 1061 1082 0.96
4 24 8.2 5.7e+02 1.7 0.2 1 23 1122 1145 1122 1145 0.89
5 24 0.0013 0.092 13.7 0.6 2 21 1155 1174 1154 1175 0.95
6 24 0.29 20 6.3 0.6 2 23 1183 1205 1182 1205 0.93
7 24 0.0034 0.24 12.4 1.2 3 23 1224 1245 1222 1245 0.95
8 24 0.00048 0.033 15.1 0.4 1 23 1250 1273 1250 1273 0.93
9 24 0.085 5.9 8.0 0.0 1 23 1299 1322 1299 1322 0.91
10 24 0.02 1.4 10.0 3.4 1 23 1327 1349 1327 1349 0.97
11 24 0.016 1.1 10.2 0.2 1 23 1355 1378 1355 1378 0.95
12 24 0.018 1.2 10.1 1.2 1 23 1391 1413 1391 1413 0.97
13 24 0.00019 0.013 16.3 1.8 1 23 1469 1492 1469 1492 0.97
14 24 5.4e-05 0.0038 18.0 0.6 1 23 1544 1567 1544 1567 0.96
15 24 0.0022 0.15 13.0 1.5 2 23 1589 1611 1588 1611 0.95
16 24 0.021 1.5 9.9 0.1 2 23 1617 1639 1616 1639 0.94
17 24 0.007 0.48 11.4 0.3 1 21 1682 1702 1682 1703 0.95
18 24 0.0013 0.09 13.7 0.6 1 23 1713 1735 1713 1735 0.93
19 24 0.00012 0.0079 17.0 0.4 2 23 1821 1843 1820 1843 0.93
20 24 3.5e-07 2.4e-05 24.9 1.4 3 23 1850 1870 1849 1870 0.98
21 24 0.004 0.28 12.1 2.2 1 23 1889 1911 1889 1912 0.95
22 24 0.36 25 6.0 0.0 1 23 1933 1955 1933 1955 0.97
23 24 0.029 2 9.4 0.6 1 23 1961 1984 1961 1984 0.95
24 24 0.00041 0.028 15.3 0.5 1 23 1992 2015 1992 2015 0.96

Sequence Information

Coding Sequence
atgaCTGTGAACTATGATCGTGTTTGTAGACTGTGCTTGTCATCTCGAGGCGAATTACTGCCGATTTTTCCTACCACCAGTTCGGATGAGTTGGAACCTCCCATCCTCGCAAGTAAAATAAAGGACTGTGTGTCAGTACAGATAAACGAAAATGACGAGCTGCCGACGAACGTCTGCAGAAAATGCGTGGATAATGTCAACAACTGGCATTTATTCAAGACTGTTTGTACAAAGGCACAAAACAAACTGTTGTCTCTCTCAAGGAAGGATGGAAGCCTACTAGAAGAGGTCCATGTCAAAAGTGAGCCATTTTCTGATGAGACTTATGATGATGGAGTGGTTATTGATGGACAGTACCCTGAGGCAGAGCCGGCTTCGAAGCTGCAACCAGAAGGTCCTCCCATCCTGGCTTCCCTGGGACTTACACCGCGGAGTGACAAGAAATATGTGGACCCACGGATGGATTGGCACCGAGTGCATGCCATCTTGGGTATGATTGAAGAGAACGAAATTATTGACAAACTACAATCTGTCGAAGAAAGTGATGAAATGCATCGTTCCGAACACAATTCAGAGTCCGAGGCTGAACTTCAAACAGACATAGATGATATCTTTGCTGATAATAAAAGAGGATACCTTTGCAAAAATAGCTCAGTCTTCGCTAAAACTCCCTTTGAAACCCCATATGGAGCTCCAAACCAAACGATTAAAGTGAAGAAACGTAAACTTGAAACTGATAGCCACTGCTTTGATCCTAAACATGCCTGGCAGCTACTGTTCACAGACGACATACTCGATATCATTGTGTCCGcaacaaacaacaaaatagAACACACCGAAGAAAACCCCACTAATGTTGAAGAAATTAAATCTCTTATCGGAATTATGTACCTGAACGGTATAATGCGGCCAACGCATCAGAAATGCAGTGACCTCTGGGACAAAGACTGCGGCGTCCCGTCGGTTATTAACGCAATGACAAACGAACGCTTCAACTTTCTCCTACAAAACATCTGTTTCTGCAGCAACGATGACGACATTATGCAGTACGATACAATGAAACGCATACGCAAGGCGTTTGAAATCTTCGCTATGAACTGCAGATCGACTCACGACGTGGAGGAGTCGGCGGTCGTCGATGAGATCATTGTGCCAGTTTACGGCCCTTGCCCGTTCCGATACGACATTGATAACAAACAGTTGAAGCGTGGCATCAAAATGGTACTTCTGGTCGATCCCAGTAATTTCTTCGTTAGCAATCTCGATGTGATTACTGATCCCTACTTCGGAGCCGATGAGATTGTGAAAAAGGTCACTCAGCACTTGTTCGGTACGGGGAAAACTATAATCATGGACAGCTGGTACTTTTCCACTGATTTAATGGATAGTCTCAAGAGTTGTAAACTGTATAGCATAGGGGCGTTACATCCAACAAGTGATGATATTCCTCCATTGTTCCTATCGCAGTTCAGAAAAAGACAGCCTTATATATCCGGGTATGCTGATAAAGCAATATCACTGACCTCACACTTGAATAAGCAATCTAAAGTAGTGAACATCATTACAAACTTGCCgcaatataacaaaaaagcTGACTCCTACGGTTCGACGTCAGTATCTGCTTACAGGAAAGACCATTCTGTAGTTGAGGTCCTTGATGTGCTAATGCACTACTATACAACCTTGCAAAATTCTAACGACTGGACTTTATCCATCTTCGCCACTCTATTGAACATCGCTTCTGTAAATGCTCAAGTAATATGGAGCGCGAAGAATTCTTCTGGTATGGAAAGTGAGAAAGAGGAAGATGAAGAATATGAAGAGGAAGTGAAAATCCCTGAGCCCGTGAAGGTCCCGCACATGCCGGAGGTGTCGATCACGGTGATGCGGCCCACGGGCGAGACGCTGCAGTCCCGACAAGGTATCCAACAGATCGCCTCCAAGGACTGCCTCATCTGCGGACGCAGCTACCGCTACTCACACAACGCCAGGAGACACGAACTCACCACGCACAAGTTCGACCGctacacaaacaaaataaacaaaccaaAAGTACACACAATGAAAccaaaactacgaccaaaccccTTCAACCCTAAAGCGCGACTCATGCCCAACCCTATAAGCCACAAAATGCAACTACTACCAAAAATAGCACCGAAATTTATGCAACAGCAAACTCAgtttaataagaaaattattacacCACCGAAACCGATACCCATAAAATCAGCGAAAACCCCTCAAAATAATCTGCCTTATCCGCTGCGAATCAAAGCACTCAAAGATTtgcaaataaagaaaaaggaACCGCAAATACTTAAAACTTTGCTCACTTCCAAGCCGGAGGTCTTGGTCTCTGAACCGGAGATATTGAATTCTGGACCTGAGAGTCCCGAGACTCTGATCTCTGAGCCTGAAATTGCCTCCTTCCAAGTGGAAACTATTCTCTCGGAGCCCAATGATTACGATGACAATCAAGACGAAGAAGAAGGAGATGAAATTCACAATAACCAGGGTCAAAACTATGATACTGTTGATATGGACTCCGAACATGAAATAGAAATCGCGCGGCAACAAGAAAGTATCCAGGACAACGAAAAAAATGACGATGCGGAAGATGTACCACAAGATAATGAAGATAACTTTGACGAAGCTGAAAATGCAAGCAAAGAAGAAAATGGCAGTGAAAAAGCGAGTTGCCCTGATACTGCGCAAGTTGATGAAGACTCGCAAAACATGGTTGTTGATGAGGGTGAAGAAACAAAAGACGATGAACAAAaccctgatgatgatgatgaaggaaATGATGATGGAGGCAATGAGGAATTAGACACAACTCAGGAGCCTGGGCAAAATGacgaagaagaagaaattCTCGGACTTACGCCTCAAATTGAAATGAACGAAGAAATGCAAAATAACACTGtgaatactgaaataaatgagGATGAAGAATTAGATGAAACCGCTGATTTTAACAATACCGCTGACGAAGATGGAACTGACGGCGGCATACAGCAAGGCTTTATCACCCCTGCTCAGAGAGATTTTATCAAAAGGTATAGAGATATCATCCTACAGATTAATACTCAAAGATGCCTTTGTTGTGATAAAGAGTATCCCCGTCGAAAAGCAGTTATTCAACATCTTCAGAAAAATGGCTACAAAGTCCCCAAGCATACCTGCTACAATTGTGTCGTTACTTTCACGCACATTGGCGCTCTCCTCAGCCACATGAGGCAGAATAATTGTACTGATTTGTGGAAGATTATATACGATGATAATGGAATTACCAGCGATATGATAGTCGAAGAACCCAAAAGCAAAATACAAGCCAAAGATATTTTCAACGCGAAATCTTACGCATGTAGATTGTGCCCTGCTAAATTTCAACTGAAACAATCTATCATGAAACATGTTGCTGAGTTCCATGAAGATGGTCAGTCGTCGGTTCCATTAACATGCGTCCACTGTGGAGTATCATACAAGGAGAAAACTCTTCTCAAAAAACATATTCGCAACGGCGATTGTACTGTGTACATTCACTGCGATTTATGCTCAGAACAATTCACCAATATGCAAGATTTTAACGATCACGCTTTGTCTGCACATGCTGAGCACTTTGTTAAATCAGAGAATCAAGCTGTTGATGGGCGACTCACCGACTGTTATATTTGTGGAACGAAAACTACCAGTTACTCGAATTTGctcaaacatttcaaatcggaccacgATCAAATCGGGCATCCGTGTCAATTTTGCGGCGCCAAGTTTGAACAGCCGGTCGATCTAAACAAACACATGTATCTGGAACATTCTGGTCAAACTCCCGACATGAGCTCCACCCAACCGGACATGTCGCTTGTCAAAGAAGAGGCTGAAGAATACCATTACTCGTGCACCGAGTGTAACGCAATATTTGAAACTGTCGACGAATGGACTGACCACCAAGTGGCTGAACACAACCAAGTGGCGCATCATTGCGATCAATGCGAAAAGAAATTCTTGAGGCCCTCGGAGCTTGCCGAACACAAGAATACCCACTTGAGGGTTAAGTTCTATCCTTGTAGTGTTTGTTCGAACTCTTACAGCACTCCGCAAAAATTATCCGAGCATGTGCAGAATGCTCACCCCGGTGCCGGTTCCAATGCCAACCCTGAATTCGAATTCTTCTGCGAAACGTGCATACGACCATTCAAGAGTCGTCAGGCTTACTCCAATCATATGCGTATACACGCCAAAGTACCAACCACTAACAGAAAACCCACAGAAAAATCTTTGGGAGCTCCCAAAGAGTTTGATCCTCGTATTATTGGAAAACCTATCAAACAGTTTACAATGGCCAATGTGGCTCAGCCTGCAGTTCTTTTTAAACCTAACGCAAATGTGCCGAACGCACCTTATTCGTGTGATATTTGCGGAAAAGGTTTCATgcataagaaaaatatttggaaACACAAGAAAGTGTTACACGCTGATATTATTAACGATAGAAATGACAGCGAAGAGAACACGATGCATGCTTCCACCGAAGAAGATGAATACAATGGTGATGAAAATGGCTCTATGCTTACGACGCCACAATTCAATAGTTTTGCTTTTCCGATAGAACCTACTCCTTCTATTTTTGAATGTGAACTATGTGGAAAGCAGTTCCCACTGAAATCTAGTTTGATTAAGCACAAGCGTGCCAAGCACGGAATCGTCAATCACGTCAATTCGGAACCACAGACGCCCTCCTCTGAAGGAACCGGTCGGTCCAGTTGTACCATTTGCAAAATAACATTTGCAGATAAAAAGTCCTATTATCGCCACAGAAAGAATGTTCATAAATCAGCTACTCAAATGTGTAAGATTTGTGGAAAACCATTGAACTCCACCCAAGAGCTTTACGAGCATCTAAAGGCAGCCCACTCGAGCTTGCTGCTAGGCTATGACGCTACTCAAAGCGCAAATAAAACTCAGGACATATCACAAGATATCGAACCCGAGTACGACGAGCCTGAACCTGTTAACCCCAGTGTCGAGTACCAGGCGAGATACCCGTGCGATACGTGCGGCAAACAATTTGTAGGTTTGCTATCTTTACAAAACCATCAATGCATAAGTCAGCCACCTACGCAGCCGCAGACTTTCGATTGTGAAATTTGTCACAAAAGCTACACATCCATTGCTGCTTTGAAAAGCCACCGCGGCTGGCATCTTCGATCTCCTGATGGGAAAGCCGCTGCCAACAACAGTGGCCTTTGGATGCCTCAACACAAAGTTACTAGTAAGGTCAGCAAACATGAAGTCTTAGAACCTACCCCGCCGGCACGATCGGTACAACAGTCTGCCTCCATAGCTAAACGGAGGCTACCGCCCGAAGTAGAAGTAACCGTTGTGAACCCTAACAAAAAGATGCGTTCCGACGATTCCGTCGAGATGGAACAAAATAACGAAACGTTGGAAGGTAAATATTGCACCATATGTGATAAAGAGTTCACTAAACGCGCCGCGTACCAACGCCATATGGATGAAGTTCACCAACCGAACTCGGTGTTTTGTCCCGTCTGTGATAAGAGTTTTACGCGAAAATCCACTTTGCTTGTGCATATGAAGAAGCATTACGAAGGTGGCGAAGGTAGTTCTTCAACTGCTCCGGTGGACGAAGAGGAGGGGTTTTCGTGCGAAGTTTGCGGTACGGTGTGCGAAACTGAAAACACGTTGCGAGCGCACAAGATAAGGCATCATGGTGAGGATTCGGCGGATTCTGAGGACGATGGTGAAGTGCCTATGCCGCAGCCCGGCGAGTTCACGTGTGGCCAGTGTGGGGACGGCGTGGCGACCGCGCGCGATCTCATCACGCACCGCGCCATACACTCCACGCAAACCAAATTCTTCTGTAACATTTGCAAAGTGTACTTCGCTAGAGCCTTGGACTTGTCCTCGCACACGCGCGCGCGGCACGCTGACAATGAGAAAGTGTTCTTCCCCTGTGCCATGTGTGATCGCTTTTACATGAACAAGAAAAGTTTGCAACGACACATCGATATGGTTCAttga
Protein Sequence
MTVNYDRVCRLCLSSRGELLPIFPTTSSDELEPPILASKIKDCVSVQINENDELPTNVCRKCVDNVNNWHLFKTVCTKAQNKLLSLSRKDGSLLEEVHVKSEPFSDETYDDGVVIDGQYPEAEPASKLQPEGPPILASLGLTPRSDKKYVDPRMDWHRVHAILGMIEENEIIDKLQSVEESDEMHRSEHNSESEAELQTDIDDIFADNKRGYLCKNSSVFAKTPFETPYGAPNQTIKVKKRKLETDSHCFDPKHAWQLLFTDDILDIIVSATNNKIEHTEENPTNVEEIKSLIGIMYLNGIMRPTHQKCSDLWDKDCGVPSVINAMTNERFNFLLQNICFCSNDDDIMQYDTMKRIRKAFEIFAMNCRSTHDVEESAVVDEIIVPVYGPCPFRYDIDNKQLKRGIKMVLLVDPSNFFVSNLDVITDPYFGADEIVKKVTQHLFGTGKTIIMDSWYFSTDLMDSLKSCKLYSIGALHPTSDDIPPLFLSQFRKRQPYISGYADKAISLTSHLNKQSKVVNIITNLPQYNKKADSYGSTSVSAYRKDHSVVEVLDVLMHYYTTLQNSNDWTLSIFATLLNIASVNAQVIWSAKNSSGMESEKEEDEEYEEEVKIPEPVKVPHMPEVSITVMRPTGETLQSRQGIQQIASKDCLICGRSYRYSHNARRHELTTHKFDRYTNKINKPKVHTMKPKLRPNPFNPKARLMPNPISHKMQLLPKIAPKFMQQQTQFNKKIITPPKPIPIKSAKTPQNNLPYPLRIKALKDLQIKKKEPQILKTLLTSKPEVLVSEPEILNSGPESPETLISEPEIASFQVETILSEPNDYDDNQDEEEGDEIHNNQGQNYDTVDMDSEHEIEIARQQESIQDNEKNDDAEDVPQDNEDNFDEAENASKEENGSEKASCPDTAQVDEDSQNMVVDEGEETKDDEQNPDDDDEGNDDGGNEELDTTQEPGQNDEEEEILGLTPQIEMNEEMQNNTVNTEINEDEELDETADFNNTADEDGTDGGIQQGFITPAQRDFIKRYRDIILQINTQRCLCCDKEYPRRKAVIQHLQKNGYKVPKHTCYNCVVTFTHIGALLSHMRQNNCTDLWKIIYDDNGITSDMIVEEPKSKIQAKDIFNAKSYACRLCPAKFQLKQSIMKHVAEFHEDGQSSVPLTCVHCGVSYKEKTLLKKHIRNGDCTVYIHCDLCSEQFTNMQDFNDHALSAHAEHFVKSENQAVDGRLTDCYICGTKTTSYSNLLKHFKSDHDQIGHPCQFCGAKFEQPVDLNKHMYLEHSGQTPDMSSTQPDMSLVKEEAEEYHYSCTECNAIFETVDEWTDHQVAEHNQVAHHCDQCEKKFLRPSELAEHKNTHLRVKFYPCSVCSNSYSTPQKLSEHVQNAHPGAGSNANPEFEFFCETCIRPFKSRQAYSNHMRIHAKVPTTNRKPTEKSLGAPKEFDPRIIGKPIKQFTMANVAQPAVLFKPNANVPNAPYSCDICGKGFMHKKNIWKHKKVLHADIINDRNDSEENTMHASTEEDEYNGDENGSMLTTPQFNSFAFPIEPTPSIFECELCGKQFPLKSSLIKHKRAKHGIVNHVNSEPQTPSSEGTGRSSCTICKITFADKKSYYRHRKNVHKSATQMCKICGKPLNSTQELYEHLKAAHSSLLLGYDATQSANKTQDISQDIEPEYDEPEPVNPSVEYQARYPCDTCGKQFVGLLSLQNHQCISQPPTQPQTFDCEICHKSYTSIAALKSHRGWHLRSPDGKAAANNSGLWMPQHKVTSKVSKHEVLEPTPPARSVQQSASIAKRRLPPEVEVTVVNPNKKMRSDDSVEMEQNNETLEGKYCTICDKEFTKRAAYQRHMDEVHQPNSVFCPVCDKSFTRKSTLLVHMKKHYEGGEGSSSTAPVDEEEGFSCEVCGTVCETENTLRAHKIRHHGEDSADSEDDGEVPMPQPGEFTCGQCGDGVATARDLITHRAIHSTQTKFFCNICKVYFARALDLSSHTRARHADNEKVFFPCAMCDRFYMNKKSLQRHIDMVH

Similar Transcription Factors

Sequence clustering based on sequence similarity using MMseqs2

100% Identity
iTF_00698511;
90% Identity
-
80% Identity
-