Cv-a012847.1


Basic Information
Transcription Factor Domain
Sequence Information
Similer Transcription Factors

Basic Information

Insect
Chloroclystis v-ata
Gene Symbol
KLHL5
Assembly
GCA_963691955.1
Location
OY829903.1:17081450-17092658[+]

Transcription Factor Domain

TF Family
BTB
Domain
zf-C2H2|ZBTB
PFAM
PF00651
TF Group
Zinc-Coordinating Group
Description
The BTB (for BR-C, ttk and bab) [6] or POZ (for Pox virus and Zinc finger) [1] domain is present near the N-terminus of a fraction of zinc finger (Pfam:PF00096) proteins and in proteins that contain the Pfam:PF01344 motif such as Kelch and a family of pox virus proteins. The BTB/POZ domain mediates homomeric dimerisation and in some instances heteromeric dimerisation [1]. The structure of the dimerised PLZF BTB/POZ domain has been solved and consists of a tightly intertwined homodimer. The central scaffolding of the protein is made up of a cluster of alpha-helices flanked by short beta-sheets at both the top and bottom of the molecule [2]. POZ domains from several zinc finger proteins have been shown to mediate transcriptional repression and to interact with components of histone deacetylase co-repressor complexes including N-CoR and SMRT [5, 3, 4]. The POZ or BTB domain is also known as BR-C/Ttk or ZiN.
Hmmscan Out
# of c-Evalue i-Evalue score bias hmm coord from hmm coord to ali coord from ali coord to env coord from env coord to acc
1 21 7e-10 2.2e-07 31.4 0.0 1 40 68 106 68 115 0.92
2 21 3.7e-08 1.2e-05 25.9 0.0 8 40 129 160 122 169 0.87
3 21 3.7e-08 1.2e-05 25.9 0.0 8 40 183 214 176 223 0.87
4 21 3.7e-08 1.2e-05 25.9 0.0 8 40 237 268 230 277 0.87
5 21 3.7e-08 1.2e-05 25.9 0.0 8 40 291 322 284 331 0.87
6 21 3.7e-08 1.2e-05 25.9 0.0 8 40 345 376 338 385 0.87
7 21 3.7e-08 1.2e-05 25.9 0.0 8 40 399 430 392 439 0.87
8 21 3.7e-08 1.2e-05 25.9 0.0 8 40 453 484 446 493 0.87
9 21 3.7e-08 1.2e-05 25.9 0.0 8 40 507 538 500 547 0.87
10 21 3.7e-08 1.2e-05 25.9 0.0 8 40 561 592 554 601 0.87
11 21 3.7e-08 1.2e-05 25.9 0.0 8 40 615 646 608 655 0.87
12 21 3.7e-08 1.2e-05 25.9 0.0 8 40 669 700 662 709 0.87
13 21 3.7e-08 1.2e-05 25.9 0.0 8 40 723 754 716 763 0.87
14 21 3.7e-08 1.2e-05 25.9 0.0 8 40 777 808 770 817 0.87
15 21 3.7e-08 1.2e-05 25.9 0.0 8 40 831 862 824 871 0.87
16 21 3.7e-08 1.2e-05 25.9 0.0 8 40 885 916 878 925 0.87
17 21 3.7e-08 1.2e-05 25.9 0.0 8 40 939 970 932 979 0.87
18 21 3.7e-08 1.2e-05 25.9 0.0 8 40 993 1024 986 1033 0.87
19 21 3.7e-08 1.2e-05 25.9 0.0 8 40 1047 1078 1040 1087 0.87
20 21 3.7e-08 1.2e-05 25.9 0.0 8 40 1101 1132 1094 1141 0.87
21 21 9.4e-16 3e-13 50.3 0.0 8 105 1155 1249 1148 1253 0.88

Sequence Information

Coding Sequence
atgtgtatgtattcGACAAAAGTCCCAGTTTTTCTACATCAGCACAAAGCCAAGACTGATCTGAGCAAAAGTTTGCTAGTTCCCTATAAAAAGATTCCTGAGGATCGCAGTGGCTCGGAAGGCAGCGAAGGCGAAGCGGAATTGGAATCCGAGGAGTTATCCCTGGTGGACGTGGGAGCGCCCGCGCGCGCGCTCGGAGCGCTGAACGCGCTGCGCAAGTCGCGCCAGCACTACGACGTGGTGCTggtggcgggcggcgcggaggTGCCGGCGCACCGCGCGGTGCTGGCCGCCGCCTCGCCGTACCTGCTGGAGGCGCTGGCGCCCGCCTCGCCGCCCGGCGCGCCCTACAGAGTGCAGGTAAACACTACATCATCTACAGCACGGCAGCACTACGACGTGGTGCTggtggcgggcggcgcggaggTGCCGGCGCACCGCGCGGTGCTGGCCGCCGCCTCGCCGTACCTGCTGGAGGCGCTGGCGCCCGCCTCGCCGCCCGGCGCGCCCTACAGAGTGCAGGTAAACACTACATCATCTACAGCACGGCAGCACTACGACGTGGTGCTggtggcgggcggcgcggaggTGCCGGCGCACCGCGCGGTGCTGGCCGCCGCCTCGCCGTACCTGCTGGAGGCGCTGGCGCCCGCCTCGCCGCCCGGCGCGCCCTACAGAGTGCAGGTAAACACTACATCATCTACAGCACGGCAGCACTACGACGTGGTGCTggtggcgggcggcgcggaggTGCCGGCGCACCGCGCGGTGCTGGCCGCCGCCTCGCCGTACCTGCTGGAGGCGCTGGCGCCCGCCTCGCCGCCCGGCGCGCCCTACAGAGTGCAGGTAAACACTACATCATCTACAGCACGGCAGCACTACGACGTGGTGCTggtggcgggcggcgcggaggTGCCGGCGCACCGCGCGGTGCTGGCCGCCGCCTCGCCGTACCTGCTGGAGGCGCTGGCGCCCGCCTCGCCGCCCGGCGCGCCCTACAGAGTGCAGGTAAACACTACATCATCTACAGCACGGCAGCACTACGACGTGGTGCTggtggcgggcggcgcggaggTGCCGGCGCACCGCGCGGTGCTGGCCGCCGCCTCGCCGTACCTGCTGGAGGCGCTGGCGCCCGCCTCGCCGCCCGGCGCGCCCTACAGAGTGCAGGTAAACACTACATCATCTACAGCACGGCAGCACTACGACGTGGTGCTggtggcgggcggcgcggaggTGCCGGCGCACCGCGCGGTGCTGGCCGCCGCCTCGCCGTACCTGCTGGAGGCGCTGGCGCCCGCCTCGCCGCCCGGCGCGCCCTACAGAGTGCAGGTAAACACTACATCATCTACAGCACGGCAGCACTACGACGTGGTGCTggtggcgggcggcgcggaggTGCCGGCGCACCGCGCGGTGCTGGCCGCCGCCTCGCCGTACCTGCTGGAGGCGCTGGCGCCCGCCTCGCCGCCCGGCGCGCCCTACAGAGTGCAGGTAAACACTACATCATCTACAGCACGGCAGCACTACGACGTGGTGCTggtggcgggcggcgcggaggTGCCGGCGCACCGCGCGGTGCTGGCCGCCGCCTCGCCGTACCTGCTGGAGGCGCTGGCGCCCGCCTCGCCGCCCGGCGCGCCCTACAGAGTGCAGGTAAACACTACATCATCTACAGCACGGCAGCACTACGACGTGGTGCTggtggcgggcggcgcggaggTGCCGGCGCACCGCGCGGTGCTGGCCGCCGCCTCGCCGTACCTGCTGGAGGCGCTGGCGCCCGCCTCGCCGCCCGGCGCGCCCTACAGAGTGCAGGTAAACACTACATCATCTACAGCACGGCAGCACTACGACGTGGTGCTggtggcgggcggcgcggaggTGCCGGCGCACCGCGCGGTGCTGGCCGCCGCCTCGCCGTACCTGCTGGAGGCGCTGGCGCCCGCCTCGCCGCCCGGCGCGCCCTACAGAGTGCAGGTAAACACTACATCATCTACAGCACGGCAGCACTACGACGTGGTGCTggtggcgggcggcgcggaggTGCCGGCGCACCGCGCGGTGCTGGCCGCCGCCTCGCCGTACCTGCTGGAGGCGCTGGCGCCCGCCTCGCCGCCCGGCGCGCCCTACAGAGTGCAGGTAAACACTACATCATCTACAGCACGGCAGCACTACGACGTGGTGCTggtggcgggcggcgcggaggTGCCGGCGCACCGCGCGGTGCTGGCCGCCGCCTCGCCGTACCTGCTGGAGGCGCTGGCGCCCGCCTCGCCGCCCGGCGCGCCCTACAGAGTGCAGGTAAACACTACATCATCTACAGCACGGCAGCACTACGACGTGGTGCTggtggcgggcggcgcggaggTGCCGGCGCACCGCGCGGTGCTGGCCGCCGCCTCGCCGTACCTGCTGGAGGCGCTGGCGCCCGCCTCGCCGCCCGGCGCGCCCTACAGAGTGCAGGTAAACACTACATCATCTACAGCACGGCAGCACTACGACGTGGTGCTggtggcgggcggcgcggaggTGCCGGCGCACCGCGCGGTGCTGGCCGCCGCCTCGCCGTACCTGCTGGAGGCGCTGGCGCCCGCCTCGCCGCCCGGCGCGCCCTACAGAGTGCAGGTAAACACTACATCATCTACAGCACGGCAGCACTACGACGTGGTGCTggtggcgggcggcgcggaggTGCCGGCGCACCGCGCGGTGCTGGCCGCCGCCTCGCCGTACCTGCTGGAGGCGCTGGCGCCCGCCTCGCCGCCCGGCGCGCCCTACAGAGTGCAGGTAAACACTACATCATCTACAGCACGGCAGCACTACGACGTGGTGCTggtggcgggcggcgcggaggTGCCGGCGCACCGCGCGGTGCTGGCCGCCGCCTCGCCGTACCTGCTGGAGGCGCTGGCGCCCGCCTCGCCGCCCGGCGCGCCCTACAGAGTGCAGGTAAACACTACATCATCTACAGCACGGCAGCACTACGACGTGGTGCTggtggcgggcggcgcggaggTGCCGGCGCACCGCGCGGTGCTGGCCGCCGCCTCGCCGTACCTGCTGGAGGCGCTGGCGCCCGCCTCGCCGCCCGGCGCGCCCTACAGAGTGCAGGTAAACACTACATCATCTACAGCACGGCAGCACTACGACGTGGTGCTggtggcgggcggcgcggaggTGCCGGCGCACCGCGCGGTGCTGGCCGCCGCCTCGCCGTACCTGCTGGAGGCGCTGGCGCCCGCCTCGCCGCCCGGCGCGCCCTACAGAGTGCAGGTAAACACTACATCATCTACAGCACGGCAGCACTACGACGTGGTGCTggtggcgggcggcgcggaggTGCCGGCGCACCGCGCGGTGCTGGCCGCCGCCTCGCCGTACCTGCTGGAGGCGCTGGCGCCCGCCTCGCCGCCCGGCGCGCCCTACAGAGTGCAGGTAAACACTACATCATCTACAGCACGGCAGCACTACGACGTGGTGCTggtggcgggcggcgcggaggTGCCGGCGCACCGCGCGGTGCTGGCCGCCGCCTCGCCGTACCTGCTGGAGGCGCTGGCGCCCGCCTCGCCGCCCGGCGCGCCCTACAGAGTGCAGGAAGTGGAAGGCGAGGCTCTACGCGCCCTGGTGGAGTACGCGTACACGGGGCGGCTCGCGGTGCGCGACGCGGCCGACGCGCGCCGCCTCTACCGCGCCGCCTGGCGGCTGCGGCtggaggcggcgcgcgcgcatctCGCTGAACGACTGCTGCTCAGGCTGCAGCCGCAAGATTGTCTGGCCGTGCGCGCGCTGCCCGGACTCGCGGCCGATCAGCTGTTAACTTTGGATAAATATATCGCGGATAATTTCGACGAGCTATGCTCCTGCGGCGCACTAGCCACACTGCCCCAGATCCGCTTAGAAGTAATGAAAGGGGAGGATGGGGCAGGCACGGGTGGGGATGAAACGCCCCTCACGGTGGCGGACGCGGCGCTCGCCTGGCTGCGTGACCAGCCGCACACAGACAGAGATTTCACAGAACTGTGCTCCCGCACGCACCTCGTGTACGTGGACAACCGCGGGCACCTCCGCGACTGCGGCGACCTGCCCGCCGCCAGCGGGGACGCGCCCGAGCTGCAGCTGTACCGCCGCGAgagcgccgcgcgccgccgcgccccgcccgcgccccccgcgccgcgccccctGCCCGCGCTGCACCTGGGACAAAGGACGGACGGAACACAATGCGCAGTGCTGGGCGCGCGCGGCTGCCTGGGCGGTGGGTGccgcgcgctgctggccgtgAACGGGCGGCTGGCCGGCGCGCTGGCCACCTGGTCCGGcgtggcgcgcgccgccgccgcacccAAGGCGGCGCTGCAGGGCGGCGCTAAGCTGGCCAGTCTCAATCATGGACCTAGATGCGCGCTGGGCGCGGCGGCCCTGGGCGCGCGGCTGCTGTGCTGCGGCGGCTACGACCGCGGCCGCGTGCTGCGCGCCGCCGAGCTATACTGCCCGCGCACCAACGTGTGGTCCCCCGCGCCCGACATGCGCCGCGAGCGGGCGCGCTTCGTGGCCGCCAGTCTCGCGGGCACAGTCTACGTGATAGGCGGGAGCGACGGACACGCGGAACTGGATACCGTCGACGCCTACAGTGCGTCCTCTCGCTGGGTCGGCGTGGCGCGCCTGCCCGTGGCCGTGGCGCACGCGGGAGGGGCGGCCGACGAGGCCCGCGGCACGCTGCACGTGGCGGGCGGGTGGTCGCAGGGCGCCTACCTGCGCCGCACCTTCACCTACAGCCCGCAGGGGGACTGCTGGAGCGAGGGCCCGCCGCTCACTACAGgCCGAGCACAATGCGCTGGCGTAATCTACCAGGACCAGATGTGGGTGCTCGGCGGCTGCGACGCTTGGCACTGCCTCGCGTCAACGGAGCgcctccccctcccccctctGGACGGGGCCCCCGCGGAGGCGGCGTGGGCGGCCGGCCCAGCGCTGGGGTCGGCGCGCCGCTCCGTGGGGGGCGCCGTGTGGAGGGGGCGGCTGGTGGCCGTGGGGGGGTCGGACGGGGCCGCCAGTCTGCGGAAGACGGATTGGTTGGAACCGGATTGGGAGCAGCACACTCCTCAGCCAGATGGACAGCAAGAAGGCAGGGGCGTCTGGCAATCCGGTCCTCTGTTAAAGCGTGCCCGCGCCGGTCCCGGCGTAGCGGTGCTGGAGGACACCCTGTACGCCGTGGGCGGGTTCGACGGGAAGGAGTTCCTGGCCTGCGCCGAGTGCCTGCTGCACCCCGACGGCGAGTGGACGGCGCTGGCGGTGCACGCCGCGCCGCAGCGGACCATCAGCAAGGGGGCAGACGACGAGGGGGACAAAAAGGAGAGGGACTCCATTGAGAAGGATTTGGTGAACGATCTCAAGAAGATCGatgttaatttgaaaaattctgaGAACGCATCAGAAAACTTAAATGACCAGCCTATAGCAACCGCGGCGCACTAA
Protein Sequence
MCMYSTKVPVFLHQHKAKTDLSKSLLVPYKKIPEDRSGSEGSEGEAELESEELSLVDVGAPARALGALNALRKSRQHYDVVLVAGGAEVPAHRAVLAAASPYLLEALAPASPPGAPYRVQVNTTSSTARQHYDVVLVAGGAEVPAHRAVLAAASPYLLEALAPASPPGAPYRVQVNTTSSTARQHYDVVLVAGGAEVPAHRAVLAAASPYLLEALAPASPPGAPYRVQVNTTSSTARQHYDVVLVAGGAEVPAHRAVLAAASPYLLEALAPASPPGAPYRVQVNTTSSTARQHYDVVLVAGGAEVPAHRAVLAAASPYLLEALAPASPPGAPYRVQVNTTSSTARQHYDVVLVAGGAEVPAHRAVLAAASPYLLEALAPASPPGAPYRVQVNTTSSTARQHYDVVLVAGGAEVPAHRAVLAAASPYLLEALAPASPPGAPYRVQVNTTSSTARQHYDVVLVAGGAEVPAHRAVLAAASPYLLEALAPASPPGAPYRVQVNTTSSTARQHYDVVLVAGGAEVPAHRAVLAAASPYLLEALAPASPPGAPYRVQVNTTSSTARQHYDVVLVAGGAEVPAHRAVLAAASPYLLEALAPASPPGAPYRVQVNTTSSTARQHYDVVLVAGGAEVPAHRAVLAAASPYLLEALAPASPPGAPYRVQVNTTSSTARQHYDVVLVAGGAEVPAHRAVLAAASPYLLEALAPASPPGAPYRVQVNTTSSTARQHYDVVLVAGGAEVPAHRAVLAAASPYLLEALAPASPPGAPYRVQVNTTSSTARQHYDVVLVAGGAEVPAHRAVLAAASPYLLEALAPASPPGAPYRVQVNTTSSTARQHYDVVLVAGGAEVPAHRAVLAAASPYLLEALAPASPPGAPYRVQVNTTSSTARQHYDVVLVAGGAEVPAHRAVLAAASPYLLEALAPASPPGAPYRVQVNTTSSTARQHYDVVLVAGGAEVPAHRAVLAAASPYLLEALAPASPPGAPYRVQVNTTSSTARQHYDVVLVAGGAEVPAHRAVLAAASPYLLEALAPASPPGAPYRVQVNTTSSTARQHYDVVLVAGGAEVPAHRAVLAAASPYLLEALAPASPPGAPYRVQVNTTSSTARQHYDVVLVAGGAEVPAHRAVLAAASPYLLEALAPASPPGAPYRVQVNTTSSTARQHYDVVLVAGGAEVPAHRAVLAAASPYLLEALAPASPPGAPYRVQEVEGEALRALVEYAYTGRLAVRDAADARRLYRAAWRLRLEAARAHLAERLLLRLQPQDCLAVRALPGLAADQLLTLDKYIADNFDELCSCGALATLPQIRLEVMKGEDGAGTGGDETPLTVADAALAWLRDQPHTDRDFTELCSRTHLVYVDNRGHLRDCGDLPAASGDAPELQLYRRESAARRRAPPAPPAPRPLPALHLGQRTDGTQCAVLGARGCLGGGCRALLAVNGRLAGALATWSGVARAAAAPKAALQGGAKLASLNHGPRCALGAAALGARLLCCGGYDRGRVLRAAELYCPRTNVWSPAPDMRRERARFVAASLAGTVYVIGGSDGHAELDTVDAYSASSRWVGVARLPVAVAHAGGAADEARGTLHVAGGWSQGAYLRRTFTYSPQGDCWSEGPPLTTGRAQCAGVIYQDQMWVLGGCDAWHCLASTERLPLPPLDGAPAEAAWAAGPALGSARRSVGGAVWRGRLVAVGGSDGAASLRKTDWLEPDWEQHTPQPDGQQEGRGVWQSGPLLKRARAGPGVAVLEDTLYAVGGFDGKEFLACAECLLHPDGEWTALAVHAAPQRTISKGADDEGDKKERDSIEKDLVNDLKKIDVNLKNSENASENLNDQPIATAAH

Similar Transcription Factors

Sequence clustering based on sequence similarity using MMseqs2

100% Identity
-
90% Identity
-
80% Identity
-