Basic Information

Gene Symbol
-
Assembly
GCA_963573255.1
Location
OY754305.1:629943-630675[-]

Transcription Factor Domain

TF Family
zf-LITAF-like
Domain
zf-LITAF-like domain
PFAM
PF10601
TF Group
Zinc-Coordinating Group
Description
Members of this family display a conserved zinc ribbon structure [3] with the motif C-XX-C- separated from the more C-terminal HX-C(P)X-C-X4-G-R motif by a variable region of usually 25-30 (hydrophobic) residues. Although it belongs to one of the zinc finger's fold groups (zinc ribbon), this particular domain was first identified in LPS-induced tumour necrosis alpha factor (LITAF) which is produced in mammalian cells after being challenged with lipopolysaccharide (LPS)[2]. The hydrophobic region probably inserts into the membrane rather than traversing it. Such an insertion brings together the N- and C-terminal C-XX-C motifs to form a compact Zn2+-binding structure [1].
Hmmscan Out
# of c-Evalue i-Evalue score bias hmm coord from hmm coord to ali coord from ali coord to env coord from env coord to acc
1 2 2.3e-17 1.9e-14 53.8 11.2 1 69 7 73 7 74 0.94
2 2 2.1 1.7e+03 -0.6 0.6 10 24 121 135 114 138 0.81

Sequence Information

Coding Sequence
ATGATAACAAACTTAGGACCAGAACCAACAGCAGTTGTGTGTCCTCATTGCGGAGTGTCAGTGGTCACCAAAATATCTTCAGCAATTCCAAGTTCAACACATATCTGTGCCTGTATTATGTGTATTGTTTTCTTTCCATTATTTTGGATTCCTTATTGTGTTAGTAACGACATAATAAAGCACAGATGCTCAGTGTGTAATGCAACACTCGGAACTTATATTCCGCCATCATCGGAATCTCGTAACAAAATAGCAGACGGACCTGAATATTCCAGTGATAATCCTggttttaatttatcaaataatggTAGCAATCATCTTATCTACCAAACAGACAGCACAACACATCACAGCATGACTCATTGCGTTGATACAAATACAACTGTTATTCATCATACGTCTCATTCTTATGGTGGAGATACTGGAGGAAGTTGGAGTGGGGGTGGGGACTGCGGGGGAGGGGATAGTGGGGGTGGGGACTGCGGGGGAGGGGATAGTGGGGGTGGAGGATCATGTGACTAA
Protein Sequence
MITNLGPEPTAVVCPHCGVSVVTKISSAIPSSTHICACIMCIVFFPLFWIPYCVSNDIIKHRCSVCNATLGTYIPPSSESRNKIADGPEYSSDNPGFNLSNNGSNHLIYQTDSTTHHSMTHCVDTNTTVIHHTSHSYGGDTGGSWSGGGDCGGGDSGGGDCGGGDSGGGGSCD

Similar Transcription Factors

Sequence clustering based on sequence similarity using MMseqs2

100% Identity
-
90% Identity
-
80% Identity
-