Basic Information

Gene Symbol
salm
Assembly
GCA_963573255.1
Location
OY754302.1:2804052-2808311[-]

Transcription Factor Domain

TF Family
zf-C2H2
Domain
zf-C2H2 domain
PFAM
PF00096
TF Group
Zinc-Coordinating Group
Description
The C2H2 zinc finger is the classical zinc finger domain. The two conserved cysteines and histidines co-ordinate a zinc ion. The following pattern describes the zinc finger. #-X-C-X(1-5)-C-X3-#-X5-#-X2-H-X(3-6)-[H/C] Where X can be any amino acid, and numbers in brackets indicate the number of residues. The positions marked # are those that are important for the stable fold of the zinc finger. The final position can be either his or cys. The C2H2 zinc finger is composed of two short beta strands followed by an alpha helix. The amino terminal part of the helix binds the major groove in DNA binding zinc fingers. The accepted consensus binding sequence for Sp1 is usually defined by the asymmetric hexanucleotide core GGGCGG but this sequence does not include, among others, the GAG (=CTC) repeat that constitutes a high-affinity site for Sp1 binding to the wt1 promoter [1].
Hmmscan Out
# of c-Evalue i-Evalue score bias hmm coord from hmm coord to ali coord from ali coord to env coord from env coord to acc
1 28 2.1 1.1e+02 3.7 0.0 2 23 7 28 6 28 0.92
2 28 1.3e-05 0.00071 20.1 2.1 1 23 34 56 34 56 0.96
3 28 6.3e-05 0.0033 18.0 0.0 1 23 62 84 62 84 0.98
4 28 6.5e-05 0.0035 17.9 1.4 1 23 91 113 91 113 0.99
5 28 3.6 1.9e+02 3.0 0.2 2 9 123 130 122 142 0.84
6 28 0.0001 0.0053 17.3 3.9 1 23 148 171 148 171 0.95
7 28 3.1e-05 0.0016 18.9 0.5 1 23 177 199 177 199 0.97
8 28 0.05 2.6 8.9 3.1 1 23 231 254 231 254 0.95
9 28 2.3e-05 0.0012 19.4 1.5 3 23 262 282 261 282 0.98
10 28 1.1e-05 0.00059 20.3 0.6 1 23 326 348 326 348 0.98
11 28 6e-05 0.0032 18.0 2.6 1 23 379 402 379 402 0.96
12 28 0.0011 0.059 14.0 0.2 1 23 408 430 408 430 0.97
13 28 0.0019 0.1 13.3 0.8 2 23 549 571 548 571 0.95
14 28 6.9e-06 0.00037 21.0 3.2 1 23 579 602 579 602 0.95
15 28 0.0024 0.13 13.0 0.2 3 23 607 628 605 628 0.93
16 28 0.0082 0.43 11.3 0.2 2 23 637 659 636 659 0.93
17 28 3.3e-05 0.0017 18.9 1.5 1 23 664 687 664 687 0.95
18 28 2 1.1e+02 3.8 11.3 1 23 693 715 693 716 0.94
19 28 0.0014 0.073 13.8 4.1 1 23 727 750 727 750 0.96
20 28 0.15 7.7 7.4 0.1 2 23 760 782 760 782 0.94
21 28 0.022 1.2 10.0 0.2 2 23 791 812 791 812 0.97
22 28 0.029 1.5 9.6 0.4 1 23 816 838 816 838 0.92
23 28 0.025 1.3 9.8 4.1 1 23 848 870 848 870 0.98
24 28 7.4e-05 0.0039 17.8 3.1 1 23 877 899 877 899 0.97
25 28 1.5e-08 7.9e-07 29.4 0.7 1 23 904 926 904 926 0.98
26 28 3.3e-05 0.0018 18.8 1.7 1 23 932 954 932 954 0.99
27 28 0.084 4.4 8.1 1.4 1 23 961 985 961 985 0.90
28 28 0.0046 0.24 12.1 7.4 1 21 991 1011 991 1014 0.90

Sequence Information

Coding Sequence
atggaGATTAAGCAGATTGTTTGTGAAGTTTGCGGTGAATTAGTAGACGAGGATAAGTATAGAAGGCATCTAAATAATGGACATAAAGATAAAAGGGAATTTCGATGTGATTTATGTGGAAAAGAATTTACAAgTAACTATAATCTCCAATATCATGTTGCACATCATTTGAATGAGAGAAATTATGTGTGTACGGAATGTCCTAGAGCGTATAATACAGCAGCAGATTTAGCACAACATTTTAGGATCCATGAAAAGCAGCGAGATCCATACAAGTGTGATTACTGTGGACAAGTCTTCCAAATTAGAAGTAGATATAATACACACATGCGAATACATAAAACTGAGCGTGGAAAAGGCCCAAAAGAATGCCCAATATGTGGGAAAATTGTACAAGATGTTAGAAGACACAATGAAACTGTTCACTTGAATATCCGGAACCATGAATGTGACATTTGTCACAAGAAGTTCAATAAGAAGTCGGGATTAGAAAGACATTTCTTAATGGTACATGAACAGCAAAAGAACTATATTTGTGATTTGTGTGGTAAAGCCTTTGGGGAAAAATCGTTGCTTACAAAACATAAAAGCAGACATAATTCCATTCGAACATCATTCTACTGTACTGTTTGTAAAAAGTATGTTGGTGAGATCAAAAATCATTACGAGACTACTCATGCAGATCTACCATTTGCATGTGAGCACTGCTATCGACGGTTTGCAAAACTTAGAGAATACGATAATCATATGACGTCAAAACATACAAAGTTAAGGAAGTGGCTGTGTGATCTATGTGGAAAGagatttgttgaaaaatatcaactaAAAAGGCATTTTCGGTCTCATATTAATGTCAATGGAATAACAGAAGCTGACATATCTAAACTCAAGCCTATTTATATTGGCGAGGATAGAGACAGAAAGGAACGTAAATCACCTTCTAAAACTCCGTCAAATAAAAGCAAATATAAAAAGTATGAATGCAATTTGTGTGGAAAGAAGTTTGCAGGAAAGACGTTGCTTAAAACTCATCTGATAAGGCATCAGAATAAAAAGGAGAATTATTGTAATATATGCaagatttatgatgaaaatattaaggaaCACTATGAAGCTGAGCATAATGACCTTGAGTACACTTGTGAGTTatgttttaagaaatttgcaAGAAGTTCACAgcttaaaaatcacaattccACAAATCATACAAATATTGGTGAGCATTCCTGTGATGTCTGTGGAAGAATCTTCAATAATCTAGCAGCTATAAAATCTCACGTCATGATTCATGTCAAATACGACAAAATAGAGCAGTCAGATGATGATTACAATGTTTTTGATCAAGGAAACGACTACGAGGATGATGACGAAAGTGATTATTTTGAACGAGAGACCAAACCTAACGATATTGAGAATGTCAATGTAGAAtcaattgttataaaaaaggAACCAGAAGATGAATATGACAATATTTGCTATGAATTTTCTCCAACAGCCTTGTCGATTAAGAGCGAGCATTTATCAGACAATGATGATATCGATGCTTTCGATAATGACTTTACAGACGATATAAAGGATGAAGGAAGATTGGAATCAGAAGTCAAAGTCAAAAATGTggtcaaaaaagaaattgatcaAGGCATTAAATGCAATGTTTGTAATGCAATGTTTCCCTCAAAAGATAAGTTCAAGACTCACTTTATGTCTGAGCATGTAGAGAGCAATAAGACGTCATTCTCGTGCAAGGAATGTGATAAAACATTTAAAGACAAAAAGTCTCTCAACAAtcactttaaaaatgttcacatAAAATTAGATTGTGAATATTGTAGTGAAAAGCTTACGTCTAAATATGAGCTTGAAAAACATGTTAAGGCAGAGCATGAATCTAGTGATAAAGCTTCATTAATGTGCagtttttgtggaaaaattttaatgactgaAAGGAACTTGAAACTTCATATTCAGGCAATTCATAGCGGCGACAGATTTCCATGTacaatttgtgataaaaaattcagctaCAAATCAGCGATGTATAGGCACAGagacAGGGAGCATAAAACTGGCAGAAAACATAAATGCAATAAATGTCCTCAACAATGTGCAACTAAACATGAATTGCGGCTTCATAAAGAGCATCACCATAATGTCAATCGAAAAAATACCTCTCCTGAGCACATGTGTTTTTATTGTGGAGTTTGCTTTCCATCCAGCTACGTTTTATCTCGTCATAGAAGAAGAGTTCACGGCGACGAAGATCCTGAAATTATCCGTGAATGTGGAATTTGTAAGGAAGTACTTAAAGATTTATACTGGAAACGAAAGCATATGGCACAAGTCCACTTAAATGGAAAGAAGTTGAAGAGAACTTGTGGATATTGTAAGACAGAATTTGATCTTTATGAGGAATTCAAGGCACATATTGAATCACATGTTGGACTTTTTATCTGCATAACGTGtggagaattttattttgatgctgAATCCTTAAAGTCTCATCAATACACCCATAAGAAAATCGATTGTAATTTAAGGAAGTACATTTGTGATCATTGTGGACATCGTCTCTTCACGAAACTCCAGCTTTCGATGCACATGCTTAAGCATGTTAAAAGCTTTGAGGTCCATTATTGTGATATTTGTGGCAAAGGATTCAAATTTGCATCGTCACTGTACACACATCGGAAATATCATGGAGAAGGAGAATTCGTCTGTACATATTGTGGGAAGAAGTTTGCTAGAAATTCCGATCTTGTCAATCATATTCGTACGCACACAAATGAAAAACCTTTCAAatgtCAAATTTGCGACCGTGGATTTTCATTAAAGCAGTTACTTCAATATCACCAACAAACTCATCCAGAGACAAGAGTCATgtttaaatgcaaaaagtgTGAGGATCATGtatttgttgataaaaagCAATTGACTATTCACGAAGATCAAGCACATCCTGAATTACGCCCTTATCGTTGCTTCATATGCAACATGTCCTTCAAACATGAGCATAATTTAAGGAAACATAATGCACATAAACATTTGTAA
Protein Sequence
MEIKQIVCEVCGELVDEDKYRRHLNNGHKDKREFRCDLCGKEFTSNYNLQYHVAHHLNERNYVCTECPRAYNTAADLAQHFRIHEKQRDPYKCDYCGQVFQIRSRYNTHMRIHKTERGKGPKECPICGKIVQDVRRHNETVHLNIRNHECDICHKKFNKKSGLERHFLMVHEQQKNYICDLCGKAFGEKSLLTKHKSRHNSIRTSFYCTVCKKYVGEIKNHYETTHADLPFACEHCYRRFAKLREYDNHMTSKHTKLRKWLCDLCGKRFVEKYQLKRHFRSHINVNGITEADISKLKPIYIGEDRDRKERKSPSKTPSNKSKYKKYECNLCGKKFAGKTLLKTHLIRHQNKKENYCNICKIYDENIKEHYEAEHNDLEYTCELCFKKFARSSQLKNHNSTNHTNIGEHSCDVCGRIFNNLAAIKSHVMIHVKYDKIEQSDDDYNVFDQGNDYEDDDESDYFERETKPNDIENVNVESIVIKKEPEDEYDNICYEFSPTALSIKSEHLSDNDDIDAFDNDFTDDIKDEGRLESEVKVKNVVKKEIDQGIKCNVCNAMFPSKDKFKTHFMSEHVESNKTSFSCKECDKTFKDKKSLNNHFKNVHIKLDCEYCSEKLTSKYELEKHVKAEHESSDKASLMCSFCGKILMTERNLKLHIQAIHSGDRFPCTICDKKFSYKSAMYRHRDREHKTGRKHKCNKCPQQCATKHELRLHKEHHHNVNRKNTSPEHMCFYCGVCFPSSYVLSRHRRRVHGDEDPEIIRECGICKEVLKDLYWKRKHMAQVHLNGKKLKRTCGYCKTEFDLYEEFKAHIESHVGLFICITCGEFYFDAESLKSHQYTHKKIDCNLRKYICDHCGHRLFTKLQLSMHMLKHVKSFEVHYCDICGKGFKFASSLYTHRKYHGEGEFVCTYCGKKFARNSDLVNHIRTHTNEKPFKCQICDRGFSLKQLLQYHQQTHPETRVMFKCKKCEDHVFVDKKQLTIHEDQAHPELRPYRCFICNMSFKHEHNLRKHNAHKHL

Similar Transcription Factors

Sequence clustering based on sequence similarity using MMseqs2

100% Identity
iTF_00319906;
90% Identity
-
80% Identity
-