Cten005149.1
Basic Information
- Insect
- Chironomus tentans
- Gene Symbol
- Lztr1
- Assembly
- GCA_963573255.1
- Location
- OY754302.1:55219321-55221924[-]
Transcription Factor Domain
- TF Family
- BTB
- Domain
- zf-C2H2|ZBTB
- PFAM
- PF00651
- TF Group
- Zinc-Coordinating Group
- Description
- The BTB (for BR-C, ttk and bab) [6] or POZ (for Pox virus and Zinc finger) [1] domain is present near the N-terminus of a fraction of zinc finger (Pfam:PF00096) proteins and in proteins that contain the Pfam:PF01344 motif such as Kelch and a family of pox virus proteins. The BTB/POZ domain mediates homomeric dimerisation and in some instances heteromeric dimerisation [1]. The structure of the dimerised PLZF BTB/POZ domain has been solved and consists of a tightly intertwined homodimer. The central scaffolding of the protein is made up of a cluster of alpha-helices flanked by short beta-sheets at both the top and bottom of the molecule [2]. POZ domains from several zinc finger proteins have been shown to mediate transcriptional repression and to interact with components of histone deacetylase co-repressor complexes including N-CoR and SMRT [5, 3, 4]. The POZ or BTB domain is also known as BR-C/Ttk or ZiN.
- Hmmscan Out
-
# of c-Evalue i-Evalue score bias hmm coord from hmm coord to ali coord from ali coord to env coord from env coord to acc 1 4 1.5e-13 1.5e-11 44.7 0.4 2 107 373 504 372 507 0.89 2 4 4.5 4.3e+02 1.3 0.1 77 108 506 537 503 539 0.89 3 4 9.4e-21 9e-19 67.9 0.0 8 105 598 697 592 702 0.85 4 4 4.7 4.5e+02 1.3 0.0 76 100 700 724 690 733 0.83
Sequence Information
- Coding Sequence
- ATGTCGCGAATGAGTCATTCTACCTCGTTAAAGAGCCATAAGTTCTTTTTATCAAGTGAGAAATCGAGTACATCGACCATAGTATCTACAACAGGTAGTGAATTTAACTTTGGTGCCAATATTAatcaatggaaaaaatatcCCGAAGTTGATGAATTTgTGGGTGCAAGACGTAGCAAGCATACTTGTGTATCTTTCAAAGATGCAATCTACATATTCGGAGGTGACAATGGCAAGCAAATGTTAAATGACCTCATTCGATTTGACGTCAAGGACAAGTCGTGGGGTAGAGCATTTTCAACTGGATCACCGCCAGCTCCTCGTTATCATCATTCAGCATGtgtttatgaaaaatcaatgtttatttttggtgGCTATACTGGAGATATCTTTTCCAATTCAAATCTAACAAACAAGAATGACTTATTTGAgtataaattccaaaatggtCAATGGGTTGAACGAAAGTATTTAGGAACAAAGTTTCCAGCAGCTAGAAGTGCTCACGGCAGTGCGGTTTATAATGGCTGTTTATGGATTTATGCTGGTTACGATGGCAATgTAAGACTGAATGACATGTGGAGAATTCCTTTGAATGGAAATGCTATGGAATGGGAGGAAATTAAACAATCTGGGGATGTTCCACCAACATGCTGTAATTTTCCAGTTGCCGTTGCCAGAGGATGTATGTATGTCTTTTCCGGGCAATCTGGTCTCCAAATCACAAATACTCTTTTTGAGTTCAATTTCGAAGAAAGAACTTGGAGAAAAATATCTTCTCATGACTTAATGAGAGGAAGCATTCCTACACGCCGTTATGGACACACTATGGTTCATCATGACCGTTTCCTCTATGTTTTTGGAGGAGCTGCTGATACAGCATTGCCAAATGATCTCTATTCTTTTGATTTAGACTCACAAGTCTGGAATCTTGTGATTCCTGCTCCTGATTCACAATGTCCATCTGGACGTCTTTTTCATGCAGCAGCTGTTATTAACGACTTTATGTGGATTTTTGGAGGAACTATTGAAAGTGGAGGAATGAATATTCGCAGTGGTGACATTTATAGCTTCCAGTTTTCTTCTTATCCAAAATGCACTTTATCTGATGACTTCGGAAAATTCCTtctaaacaaacaattttgtgATATTGTCTTTATTGTTGGACCGGATGAGGTGAAAATTCCAGCACATATTTCTATGGTTGCAGCAAGATCTCAGTACTTGAAAGGCAAAATTCAATCAGCAAAGGAATCTAGAAATGTgcactttgaaaaattatttgggaCAACAGACGTACAATTTTCAGCAGAACTTCCACAGTTAGAGGTCAAACTCCCAGCTGTTCAACCAGATGCTTTCGAAATGGTCCTTTCGTATATCTACACAGATATTATTGACTTTAAGGATCCttttaacaagaaaataattcttcTTATGATGCAAGTCTATTTACTGTCTCAACAATTTGATATTCCACGCTTAGAACAGCTCTGTGTCCAATACCTCGAATTTAAGATTGCCAAAACTAATGTATTAGAAGCTTTACATCATTCCGATAAGATGAATCTTCAATTAATCAAAGACTATTGcttaagttttattattaagGATGATCACTACTTTGATGTAGTAATGAGCAACGAATTTTCCTTGCTTGAGAAAAGCTTGATTGTAGAGACAGTAAGACGAAAATTGATTCCAAATAAATTGGCATCTGATATGAAATACGATAAATCTATCGGAACTACGTTAGAAAATGACATGGCTGTATTTCTAAAATCGACAGGCAaagaattttgtgacattaCACTCGTACTTGATACTCATCAGATTCCTGCTCATAAATCCATTCTAGCTGCTCGATGTGCTTACTTTCAAGCAATGTTTCGATCCTTTAATCCGGCTGATAACATCGTTAATATACAAATAGGAGAAGTAAAACCCAGTTTGGAAGCTTTTAATTCTCTACTGAGATATATTTATTATGGAGAAACGAAAATGCCAACAGAAGACAGCTTGTATTTATTTCAGGCACCATGCTTTTATGGATTCACCAACAATCGACTCCAAGCCTTTTGCAAGCATAATCTCGAGAACAACATCAATTATGAGAATGTTTTGCAAATCTTGGAAGCCTCAGACAAAATGAACGTACCAGACATAAAAAACTATGCATTACGAATGGTTGTACATGATTTTGCATTAGTTGCACGCTTGCCAAAAATGAGGCAGCTATCTCGGGAGCTTTTACTCGATATCATAAATTCAATGGCAGATGTATTGGgtgaagttaaattaaatcaagattTATTGTCATCGATAAGTATACATAGTGATATTTGA
- Protein Sequence
- MSRMSHSTSLKSHKFFLSSEKSSTSTIVSTTGSEFNFGANINQWKKYPEVDEFVGARRSKHTCVSFKDAIYIFGGDNGKQMLNDLIRFDVKDKSWGRAFSTGSPPAPRYHHSACVYEKSMFIFGGYTGDIFSNSNLTNKNDLFEYKFQNGQWVERKYLGTKFPAARSAHGSAVYNGCLWIYAGYDGNVRLNDMWRIPLNGNAMEWEEIKQSGDVPPTCCNFPVAVARGCMYVFSGQSGLQITNTLFEFNFEERTWRKISSHDLMRGSIPTRRYGHTMVHHDRFLYVFGGAADTALPNDLYSFDLDSQVWNLVIPAPDSQCPSGRLFHAAAVINDFMWIFGGTIESGGMNIRSGDIYSFQFSSYPKCTLSDDFGKFLLNKQFCDIVFIVGPDEVKIPAHISMVAARSQYLKGKIQSAKESRNVHFEKLFGTTDVQFSAELPQLEVKLPAVQPDAFEMVLSYIYTDIIDFKDPFNKKIILLMMQVYLLSQQFDIPRLEQLCVQYLEFKIAKTNVLEALHHSDKMNLQLIKDYCLSFIIKDDHYFDVVMSNEFSLLEKSLIVETVRRKLIPNKLASDMKYDKSIGTTLENDMAVFLKSTGKEFCDITLVLDTHQIPAHKSILAARCAYFQAMFRSFNPADNIVNIQIGEVKPSLEAFNSLLRYIYYGETKMPTEDSLYLFQAPCFYGFTNNRLQAFCKHNLENNINYENVLQILEASDKMNVPDIKNYALRMVVHDFALVARLPKMRQLSRELLLDIINSMADVLGEVKLNQDLLSSISIHSDI
Similar Transcription Factors
Sequence clustering based on sequence similarity using MMseqs2
- 100% Identity
- iTF_00199156;
- 90% Identity
- iTF_00319760;
- 80% Identity
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